Precipitation mechanisms of inorganic biocompatible and related materials

Each of the model systems (carbonates, phosphates and oxalates of calcium, magnesium ammonium phosphates, layered double hydroxides – LDH) that is supposed to be studied can precipitate in the form of polymorphs, hydrates or chemically different compounds. Apart from their inherent aptness for the pure academic studies, these systems are also of practical importance because of their potential application. It is to be expected that the results of proposed investigations of calcium carbonate interactions with natural acid glycoproteins and synthetic analogues (acid poly-amino acids) will contribute to the development of new preparation method of composite biomaterials with exceptional mechanical properties. Likewise, the studies of porous calcium carbonate, hydroxyapatite and LDH, into which different classes of model organic molecules (polysaccharides, polypeptides, nucleic acids) are absorbed, will contribute to the development of organic/inorganic systems for a controlled release of active molecules in body. Besides, cognition on the conditions at which precipitation and transformation of calcium oxalates and magnesium (ammonium) phosphates take place (constituents of urinary calculi), will be a theorethical base and supplement to the clinical and epidemiological studies.

Project category
Znanstveni projekti Ministarstva znanosti, obrazovanja i športa
Project code
098-0982904-2951
Project leader / principal investigator

Associates

Dr. sc. Vesna Babić-Ivančić, viša znanstvena suradnica

Dr. sc. Ljerka Brečević, znanstvena savjetnica, umirovljena

Dr. sc. Jasminka Kontrec, znanstvena suradnica

Dr. sc. Cleo Kosanović, znanstvena savjetnica

Dr. sc. Damir Kralj, viši znanstveni suradnik

Dr. sc. Siniša Širac, istraživač

Dr. sc. Branka Njegić Džakula, asistentica

B. Sc. Marko Ukraincyzk, asistent

Project start date
01/02/2007
Project end date
31/12/2011