Ksenija Zahradka

Ksenija Zahradka

Ph.D.

+385 1 456 0971

1546
Senior Research Associate

Krilo 5/102

Department of Molecular Biology
Ruđer Bošković Institute
Bijenička 54
10000 Zagreb
Croatia

Education

1991   B.Sc. in Molecular Biology, Faculty of Science, University of Zagreb, Croatia

1994   M.Sc. in Molecular and Cellular Biology, Faculty of Science, University of Zagreb, Croatia

1999   Ph.D. in Biology, Faculty of Science, University of Zagreb, Croatia

2002   Postdoctoral training in the group of Prof. Miroslav Radman, Faculté de Médecine Necker, Université de Paris-Descartes, Paris, France 

Research Areas

Biochemistry and Molecular Biology, Biology, Genetics, Evolution and Phylogenetics, Microbiology, Natural Sciences

Specific research interests

dna recombination and repair, genome stability and dynamics, molecular mechanisms of radiation resistance

Awards and Achievements

2002    Necker Institute postdoctoral fellowship, Paris, France

2006    Excellence in science grant, Croatian Ministry of Science, Education and Sports 

2007    Croatian Annual Science Award

Classes

2005 - 2008: Graduate course “Human genetics”, Faculty of Pharmacy and Biochemistry, University of Zagreb

2008 -  :  Course “Genetic recombination and DNA repair”, PhD studies in Biology, Faculty of Science, University of Zagreb

2008 -  : Course “Mechanisms of DNA damage and repair”, PhD studies in Molecular Bioscience, University of Osijek, University of Dubrovnik and Ruđer Bošković Institute, Zagreb

Featured Publications

Buljubašić, M., Zahradka, D., Zahradka, K. (2013) RecQ helicase acts before RuvABC, RecG and XerC proteins during recombination in recBC sbcBC mutants of Escherichia coli. Research in Microbiology 164: 987-997.

Repar, J., Briški, N., Buljubašić, M., Zahradka, K., Zahradka, D. (2013) Exonuclease VII is involved in “reckless” DNA degradation in UV-irradiated Escherichia coli. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 750:96-104.

Zahradka, K., Zahradka, D. (2013) Reckless DNA Degradation. In: S. Maloy, K. Hughes (eds). Brenner's Encyclopedia of Genetics, 2nd edition, Vol. 6. San Diego: Academic Press, p. 72-74.

Buljubašić, M., Repar, J., Zahradka, K., Đermić, D., Zahradka, D. (2012) RecF recombination pathway in Escherichia coli cells lacking RecQ, UvrD and HelD helicases. DNA Repair 11: 419-430.

Repar, J., Cvjetan, S., Slade, D., Radman, M., Zahradka, D., Zahradka, K. (2010) RecA protein assures fidelity of DNA repair and genome stability in Deinococcus radiodurans. DNA Repair 9: 1151-1161.

Zahradka, K., Buljubašić, M., Petranović, M., Zahradka, D. (2009) Roles of ExoI and SbcCD nucleases in "reckless" DNA degradation in recA mutants of Escherichia coliJournal of Bacteriology 191: 1677-1687.

Petranovic, D., Michelsen, O., Zahradka, K., Silva, C., Petranovic, M., Jensen, P. R., Mijakovic, I. (2007) Bacillus subtilis strain deficient for the protein-tyrosine kinase PtkA exhibits impaired DNA replication. Molecular Microbiology 63: 1797-1805.

Zahradka, K., Slade, D., Bailone, A., Sommer, S., Averbeck, D., Petranovic, M., Lindner, A. B., Radman, M. (2006) Reassembly of shattered chromosomes in Deinococcus radiodurans. Nature 443: 569-573.

Zahradka, K., Šimić, S., Buljubašić, M., Petranović, M., Đermić, D., Zahradka, D. (2006) sbcB15 and delsbcB mutations activate two types of RecF recombination pathway in Escherichia coli. Journal of Bacteriology 188: 7562-7571. 

Membership in professional associations / societies

Croatian Genetic Society

Croatian Society for Biochemistry and Molecular Biology

Croatian Microbiological Society

Miscellaneous

Mentor of three diploma students and two PhD students (University of Zagreb)

Reviewer for international scientific journals (PLoS Genetics, Journal of Molecular Biology, BMC Molecular Biology, FEMS Microbiology Letters, Archives of Microbiology, Radiation Physics and Chemistry)

Member of Organizing and/or Scientific Committee of several scientific meetings

President of the Organizing Committee of the Scientific Symposium “50 Years of Molecular Biology in Croatia”, Zagreb, Croatia (2008)

Co-leader of the research group "Life under extreme conditions", Mediterranean Institute for Life Sciences (MedILS), Split, Croatia (2007-2010)

Member of the research group "Biology of robustness", Mediterranean Institute for Life Sciences (MedILS), Split, Croatia (since 2011)

Vice-chair of the Knowledge and Invention Program, Adris Foundation, Croatia