Sunday, September 14^th

G. KLEBE

Institute of Pharm.Chem. Germany

 From hit to lead to drug candidate: new approaches in structure-based drug design

Y. ENGELBORGHS

University of Leuven, Belgium

Time resolved fluorescence applied to the study of molecular interactions

Monday, September 15^th

G. KLEBE

Institute of Pharm.Chemistry, Germany

Understanding ligand binding affinity and selectivity

N. BAN

ETH, Switzerland

X-ray crystallographic structure determination of large asymmetric macromolecular assemblies

M. EIGEN

MPI, Germany

Concepts of molecular evolution: Information space, quasi species, error threshold and antiviral strategy I

T. JOVIN

MPI, Germany

Fluorescence expression and other probes of protein-protein interactions in the cell

Y.ENGELBORGHS

University of Leuven, Belgium

Time resolved fluorescence of proteins

F. SEPAROVIC

University of Melbourne, Australia

Biological solid state NMR: an introdution

Tuesday, September 16^th

N. BAN

ETH, Switzerland

Ribosome architecture and functional aspects of protein synthesis

N. BAN

ETH, Switzerland

Protein synthesis, trans-translation and beyond

M. EIGEN

MPI, Germany

Concepts of molecular evolution: Information space, quasi species, error threshold and antiviral strategy II

T. JOVIN

MPI, Germany

Fluorescence spectroscopy in the microscope: Förster resonance energy transfer (FRET) and fluorescence / phosphorescence lifetimes (FLIM)

I. PECHT

Weizmann Institute, Israel

Allosteric control of the intra-protein electron transfer. The cd1 cytochrome nitrite reductase case

F. SEPAROVIC

University of Melbourne, Australia

Solid-state NMR studies of biological membranes

Wednesday, September 17^th

G. KLEBE

Institute of Pharm.Chemistry, Germany

Differences in binding of stereoisomers to protein active sites

T. JOVIN

MPI, Germany

Fluorescence microscopy as a biochemical and cell biological tool

M. EIGEN

MPI, Germany

Concepts of molecular evolution: Information space, quasi species, error threshold and antiviral strategy III

I. PECHT

Weizmann Institute, Israel

Real-time analysis of ligand binding to the T-cell antigen receptor; A consecutive multi-step process promoted by primary association with CD8

F. HILLENKAMP

University of Münster, Germany

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS): Principles and techniques I

F. SEPAROVIC

University of Melbourne, Australia

NMR stucture determination of membrane associated proteins and peptides

R. RIGLER

Karolinska Institute, Sweden

Basic introduction to fluorescence correlation spectroscopy (FCS) and single molecule spectroscopy

Thursday, September 18^th

W. F. van GUNSTEREN

ETH, Switzerland

Computer simulations of biomolecular systems: Advances in methods and applications

F. HILLENKAMP

University of Münster, Germany

Analysis of ologonucleotides by MALDI-MS

C.R. CANTOR

Sequenom Inc., USA

Mass spectrometry of DNA comes of age: Pushing the frontiers of quantitation and sensitivity

I. PECHT

Weizmann Institute, Israel

Regulation of mast cell secretion of inflammatory mediators: Inhibitory molecules and desensitization processes

G. VERKHIVKER

Pfizer, USA

Simulating disorder-order transitions in molecular recognition of unstructured proteins: Where folding meets binding

J. PETER-KATALINIĆ

University of Münster, Germany

Identification of protein structure and modification by Electrospray Mass Spectrometry in Proteomics

Friday, September 19^st

W.  Van GUNSTEREN

ETH, Switzerland

Advances in the computation of free energy and binding constants for biomolecular complexes

C.R. CANTOR

Sequenom Inc., USA

Finding the genes responsible for complex human diseases

C.R. CANTOR

Sequenom Inc., USA

Engineered regulatory networks: Can cells be taught to behave like electronic circuits?

G. VERKHIVKER

Pfizer, USA

Computational engineering of protein-protein interfaces for structure-based drug design: From detecting binding sites and identifying hot spots on protein surfaces to designing novel inhibitor scaffolds and specificities

R. RIGLER

Karolinska Institute, Sweden

Gene analysis at the single molecule level

J. PETER-KATALINIĆ

University of Münster, Germany

Accurate mass determination for biopolymers by Fourier Transform Ion Cyclotron Resonance Mass Spectroscopy at 9.4 T

Y.ENGELBORGHS

University of Leuven, Belgium

Using fluorescence correlation spectroscopy to study molecular interactions. Application to HIV-1 integrase and tubulin

Saturday, September 20^th

W. Van GUNSTEREN

ETH, Switzerland

Computer simulation of peptide folding: Analysis of solvent effects and the interpretation of experimental data

R. RIGLER

Karolinska Institute, Sweden

Memory landscape of single enzyme molecules

A. GRÄSLUND

Stockholm University, Sweden

NMR and three-dimensional structure of biological macromolecules in solution

H. RÜTERJANS

University of Frankfurt, Germany

Structures, functions and dynamics of proteins as described by NMR-spectroscopy   

A. GRÄSLUND

Stockholm University, Sweden

NMR studies of protein dynamics

J.L. ARRONDO

University of Basque Country, Spain

Infrared spectroscopy of membranes. Lipid

domains and proteins

J.P.G. BUTLER

MRC; UK

Genetic modification: The techniques underlying sequencing, protein production and much else

Monday, September 22^nd

A. TRAMONTANO

University of Rome, Italy

Protein evolution and structural divergence

A: ENGEL

University of Basel, Switzerland

The art of 2D crystallization

H. VOGEL

Swiss Fed. Institute of Tech., Switzerland

Selfassembly of biopolymers at interfaces

F. HILLENKAMP

University of Münster, Germany

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS): Principles and techniques II

C. OTTO

University of Twente, The Netherlands

Raman spectroscopy and microscopy of biomolecules and cells

N. BURNETTE

USA

The fallout of 9/11: business opportunity for biomedical and biophysical technologies in chemical and biological defense

Tuesday, September 23^rd

E. EVANS

Boston University, USA

Probing the relation between force – time chemistry at the level of single molecules

J.L. ARRONDO

University of Basque Country, Spain

Two dimensional infrared spectroscopy

H. J. STEINHOFF

University of Osnabrück, Germany

Watching membrane proteins move using time resolved EPR spectroscopy

J. PENNISTON

Myo Clinic, USA

Calcium, calmodulin, pumps amd memory

H. VOGEL

Swiss Fed. Institute of Tech., Switzerland

Bioanalytics in the micro- and nanometer range

Wednesday, September 24^th                                       

M. RADMAN

University of Paris, France

The genesis of mutation

M. RADMAN

University of Paris, France

Mutation and recombination in evolution and disease

C. OTTO

University of Twente, The Netherlands

Coherent ani-Stokes Raman spectroscopy and microscopy of biomolecules and cells

H. VOGEL

Swiss Fed. Institute of Tech., Switzerland

Investigating neuroreceptors by spectroscopic techniques

J.L. ARRONDO

University of Basque Country, Spain

Infrared studies of lipoproteins

E. EVANS

Boston University, USA

Probing the relation between force – time chemistry at the level of single molecules

A. TRAMONTANO

University of Rome, Italy

Methods for protein structure prediction

Thursday, September 25^th                                           

A: ENGEL

University of Basel, Switzerland

Electron crystallography, a solid tool for membrane structure analysis

J.P.G. BUTLER

MRC; UK

Analytical centrifugation: Looking at aggregation in free solution

E. EVANS

Boston University, USA

Using dynamic tension spectroscopy to probe protein insertion in membranes

A: ENGEL

University of Basel, Switzerland

Atomic force microscopy of native membrane machines: I

E. EVANS

Boston University, USA

Chemical kinetics

A. TRAMONTANO

University of Rome, Italy

Assessement of the quality of present modelling techniques

Friday, September 26th

C. OTTO

University of Twente, The Netherlands

Single molecule optical microscopy to visualize biomolecular interactions

M. RADMAN

University of Paris, France

Fidelity of biosynthetic processes

H. J. STEINHOFF

University of Osnabrück, Germany

High-field EPR Spectroscopy of membrane proteins

J.P.G. BUTLER

MRC; UK

Human Immunodeficiency Virus (HIV): The life cycle and control of a complex virus