dr. sc. Marina Ilakovac Kveder
Obrazovanje
1981. diplomirala fiziku na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu; 1985. magistrirala iz područja medicinske fizike na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu ;1988. stekla stupanj doktora prirodnih znanosti iz područja fizike na Sveučilištu u Zagrebu;
Usavršavanje:
1986.-1988. Institut J.Stefan, Sveučilište u Ljubljani, Slovenija: primjena metoda nuklearne mgnetske rezonancije (NMR grupa Prof. Roberta Blinca ) i elektronske paramagnetske rezonancije (EPR grupa Prof. Milana Schare) u izučavanju bioloških sistema;
1992.-1994. Alexander von Humboldt poslijedoktorska stipendija na Goethe Univerzitetu Frankfurt, Njemačka s projektom: Višedimenzionalna NMR spektroskopija FABP (proteina koji veže masne kiseline, grupa Prof. Heinz Rueterjansa);
Zaposlenje i dužnosti:
od 1982.- zaposlena u Institutu Ruđer Bošković
1982. zaposlena kao asistent postdiplomand;
1985. izabrana u znanstveno zvanje znanstvenog asistenta;
1988 izabrana u znanstveno zvanje višeg asistenta;
1998. izabrana u znanstveno zvanje znanstveni suradnik;
2003. izabrana u znanstveno zvanje i na radno mjesto višeg znanstvenog suradnika;
2006. izabrana u znanstveno zvanje znanstvenog savjetnika; 2006. izabrana u naslovno znanstveno-nastavno zvanje docenta, PMF;
2008. izabrana na radno mjesto znanstvenog savjetnika;
2012. izabrana u naslovno znanstveno-nastavno zvanje naslovnog izvanrednog profesora, PMF;
2013. izabrana u znanstvenog savjetnika, trajno zvanje.
2018. izabrana u naslovno zvanje redovitog profesora na Sveučilištu u Zagrebu, PMF, i Sveučilištu u Osijeku
Projekti
Voditeljica HRZZ projekta SPES (2018-2022)
Voditeljica HRZZ projekta DESiRe (2013-2017)
Alexander von Humboldt research group linkage project entitled The study of soft condensed matter by EPR: dynamics in glassy and crystalline matrices (2011-2014);
Predstavnik Hrvatske u MC odborima COST akcija:
CA15128 Molecular Spintronics, 2016. – 2020.
MP1302 NanoSpectroscopy (2013-2017)
CM1005 Supramolecular chemistry in water (2011-2015).
dugogodišnji član organizacijskog odbora serije International Summer School on Biophysics: Supramolecular structure and Function, Rovinj;
Nagrade i priznanja
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Nastava
- sudjelovanje u dodiplomskoj (PMF) i poslijediplomskoj nastavi (PMF, MOBI, Medicinski fakultet):
1.) od 1999. nositelj kolegija «Biomembrane», Molekularna biologija, PMF, Sveučilište u Zagrebu;
2.) od 2009.-2016. sunositelj kolegija «Biofizika stanice», PMF - diplomski studij fizike i kemije
3.) od 2000. nositelj kolegija «Spinsko označavanje u biofizici» PMF - doktorski studij, Sveučilište u Zagrebu;
4.) sunositelj koelgija «EPR spektroskopija» i «Fluorescencijska spektroskopija», Biofizika- doktorski studij , PMF, Sveučilište u Zagrebu;
5.) od 2006. sunositelj kolegija «Osnove metoda magentske rezonancije» i «Supramolekularne strukture i oksidacijski stres» na poslijediplomskom interdisciplinarnom doktorskom studiju Molekularne bioznanosti (MOBI) kojeg zajednički izvode Sveučilište Josipa Jurja Strossmayera u Osijeku, Sveučilište u Dubrovniku i Institut Ruđer Bošković;
6.) od 2006. nositelj kolegija: «Biomembrane: međudjelovanje lipida i proteina» na doktorskom poslijediplomskom studiju Neuroznanost, Medicinski fakultet, Sveučilište u Zagrebu.
Istaknute publikacije
M.Kveder, Ž.Bajzer: Theoretical approach to discrimination of atrial and ventricular septal defects when the left-to-right cardiac shunt is diagnosed by radionuclide angiography, Phys.Med.Biol. 31 (1986) 663-68
M.Kveder, G.Lahajnar, R.Blinc, I.Zupančič: Non-Brownian water self-diffusion in lung tissue, Magn. Reson. Med. 6 (1988) 194-98
D.Carić, V.Tomišić, M.Kveder, N.Galić, G.Pifat, V. Magnus, M.Šoškić: Absorption and fluorescence spectra of ring-substituted indole-3-acetic acids, Biophys. Chem. 111 (2004) 247-257
M.Kveder, A.Kriško, G.Pifat, H.-J. Steinhoff: The study of structural accessibility of free thiol groups in human low-density lipoproteins, Biochim. Biophys. Acta 1631(3) (2003) 239-245
M. Kveder, Ž, Marinić, A. Kriško, D. Vikić-Topić, G. Pifat: Lipid-Protein Interactions in Human Plasma LDL Evidenced by Magnetic Resonance. Chem. Phys. Lipids 141 (2006) 225-229
M. Kveder, D. Merunka, M Jokić, B. Rakvin: Low temperature electron-spin relaxation in the crystalline and glassy states of solid ethanol. Phys. Rev. B 77 (2008) 094202
M. Kveder, D. Merunka, M Jokić, J. Makarević, B. Rakvin: Electron spin-lattice relaxation in solid ethanol: Effect of nitroxyl radical hydrogen bonding and matrix disorder. Phys. Rev. B 80 (2009) 052201
M. Kveder, M. Jokić, B. Rakvin: Fast motion in molecular solids at low temperatures: evidence from a pulsed EPR study of nitroxyl radical relaxation. J. Chem. Phys. 134 044531 (2011).
M. Kveder, D. Merunka, A. Ilakovac, B. Rakvin: A multi-frequency EPR spectroscopy approach in the detection of boson peak excitations. J. Magn. Reson. 213 (2011) 26-31.
M. Kveder, M. Jokić, B. Rakvin: Fast motion in molecular solids at low temperatures: evidence from a pulsed EPR study of nitroxyl radical relaxation. J. Chem. Phys. 134 (2011) 044531.
M. Kveder, I. Šarić, D. Merunka, M. Jokić, S. Valić, B. Rakvin: The anhydrous solid trehalose: low-temperature EPR study of glassy and boson peak modes. J. Non-Crys. Solids. 375 (2013) 19-24.
M. Kveder, B. Rakvin, Jokić, E. Reijerse: A comparative study of electron spin decoherence at X- and W- band frequencies as a function of local disorder. J. Non-Crys. Solids. 414 (2015) 27-32.
J. Jurec, B. Rakvin, M. Jokić, M. Kveder: Electron spin decoherence as a measure of nuclear spin bath frustration. J. Non-Crys. Solids. 471 (2017) 435-438. IF = 2.12.
E.I. Baibekov, J. Jurec, B. Rakvin, M. Kveder: Rabi oscillations as a tool to detect strong coupling of paramagnetic center with the nuclear spin bath. J. Non-Crys. Solids. 519 (2019) 119440. IF = 2.12.
J. You, D. Carić, B. rakvin, Z. Štefanić, K. Užarević, M. Kveder: matrix material structure depenedence of the embedded electron spin decoherence. J. Chem. Phys. 150 (2019) 164124-9.
Publikacije
Radovi u časopisima
Znanstveni i pregledni radovi
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Rakvin, B., Carić, D. & Kveder, M. (2022) CW-EPR spectra of P1 centers in HPHT diamond in the vicinity of Rabi resonance: possible standard for B1 evaluation in EPR and DNP enhanced NMR spectroscopies. Journal of magnetic resonance open, 10-11, 100039, 9 doi:10.1016/j.jmro.2022.100039.
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Horvat, G., Kveder, M. & You, J. (2021) Inter-pulse delay optimization for dynamical decoupling pulse sequences with up to six refocusing pulses. European physical journal plus, 136 (8), 842, 16 doi:10.1140/epjp/s13360-021-01832-y.
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Rakvin, B., Carić, D. & Kveder, M. (2020) Detection of the spin coherence time of P1 centers in Diamond by Double Modulation EPR spectroscopy. Applied physics letters, 117 (15), 153503, 6 doi:10.1063/5.0025833.
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Kveder, M., Rakvin, B. & You, J. (2019) A quantum many body model for the embedded electron spin decoherence in organic solids. The Journal of chemical physics, 151 (6), 164124, 9 doi:10.1063/1.5124561.
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Baibekov, E., Jurec, J., Rakvin, B. & Kveder, M. (2019) Rabi oscillations as a tool to detect strong coupling of paramagnetic center with the nuclear spin bath. Journal of non-crystalline solids, 519, 119440-- doi:10.1016/j.jnoncrysol.2019.05.016.
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You, J., Carić, D., Rakvin, B., Štefanić, Z., Užarević, K. & Kveder, M. (2019) Matrix material structure dependence of the embedded electron spin decoherence. The Journal of chemical physics, 150 (16), 164124, 9 doi:10.1063/1.5090215.
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Šaric, I., Jurec, J., Reijerse, E., Maltar-Strmečki, N., Rakvin, B. & Kveder, M. (2018) Impact of disorder on formation of free radicals by gamma-irradiation: Multi-frequency EPR studies of trehalose polymorphs. Journal of physics and chemistry of solids, 123, 124-132 doi:10.1016/j.jpcs.2018.07.013.
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Rakvin, B., Carić, D. & Kveder Marina (2018) Enhanced accuracy of the microwave field strength measurement in a CW-EPR by pulsed modulation technique. Journal of magnetic resonance (San Diego, Calif.), 287, 123-127 doi:10.1016/j.jmr.2018.01.006.
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Jurec, J., Rakvin, B., Jokić, M. & Kveder, M. (2017) Electron spin decoherence as a measure of nuclear spin bath frustration. Journal of non-crystalline solids, 471 (1), 435-438 doi:10.1016/j.jnoncrysol.2017.06.037.
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Cardona, M., Kveder, M., Baisch, U., Probert, M. & Magri, D. (2016) Water-soluble beta-aminobisulfonate building blocks for pH and Cu2+ indicators. RSC Advances, 6, 84712-84721 doi:10.1039/c6ra17791c.
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Carić, D., Rakvin, B., Kveder, M., Junker, K., Walde, P. & Reijerse, E. (2015) A multifrequency EPR study of poly(PADPA) synthesized with Trametes versicolor laccase from the aniline dimer p-aminodiphenylamine (PADPA) in the presence of anionic vesicles. Current applied physics, 15 (11), 1516-1520 doi:10.1016/j.cap.2015.08.023.
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Vojta, L., Carić, D., Cesar, V., Antunović Dunić, J., Lepeduš, H., Kveder, M. & Fulgosi, H. (2015) TROL-FNR interaction reveals alternative pathways of electron partitioning in photosynthesis. Scientific reports, 5, 10085, 9 doi::10.1038/srep10085.
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Kveder, M., Rakvin, B., Jokić, M. & Reijerse, E. (2015) A comparative study of electron spin decoherence at X- and W- band frequencies as a function of local disorder. Journal of non-crystalline solids, 414, 27-32 doi:10.1016/j.jnoncrysol.2015.02.003.
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Šarić, I., Jokić, M., Rakvin, B., Kveder, M. & Maltar-Strmečki, N. (2014) The effect of thermal treatment on radiation-induced EPR signals of different polymorphic forms of trehalose. Applied radiation and isotopes, 83 (Part A), 41-46 doi:10.1016/j.apradiso.2013.10.012.
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Kveder, M., Rakvin, B., Jokić, M. & Reijerse, E. (2013) Frozen-in disorder probed by low-temperature electron spin relaxation. Solid state communications, 167, 23-26 doi:10.1016/j.ssc.2013.04.034.
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Kveder, M., Šarić, I., Merunka, D., Jokić, M., Valić, S. & Rakvin, B. (2013) The anhydrous solid trehalose: low-temperature EPR study of glassy and boson peak modes. Journal of non-crystalline solids, 375, 19-24 doi:10.1016/j.jnoncrysol.2013.05.016.
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Merunka, D., Kveder, M., Jokić, M. & Rakvin, B. (2013) Effect of glassy modes on electron spin-lattice relaxation in solid ethanol. Journal of magnetic resonance (San Diego, Calif.), 228, 50-58 doi:10.1016/j.jmr.2012.12.016.
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Andreis, M., Carić, D., Šijaković Vujičić, N., Jokić, M., Žinić, M. & Kveder, M. (2012) Self-assembly of gelator molecules in liquid crystals by ESR. Chemical physics, 403, 81-88 doi:10.1016/j.chemphys.2012.05.013.
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Kveder, M., Merunka, D., Ilakovac, A. & Rakvin, B. (2011) A multi-frequency EPR spectroscopy approach in the detection of boson peak excitations. Journal of magnetic resonance (San Diego, Calif.), 213 (1), 26-31 doi:10.1016/j.jmr.2011.08.029.
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Merunka, D., Kveder, M. & Rakvin, B. (2011) Effect of thermally activated dynamics on electron spin-lattice relaxation in glasses. Chemical physics letters, 515 (1/3), 19-22 doi:10.1016/j.cplett.2011.08.088.
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Kveder, M., Jokić, M. & Rakvin, B. (2011) Fast motion in molecular solids at low temperatures: evidence from a pulsed EPR study of nitroxyl radical relaxation. The Journal of chemical physics, 134 (4), 044531, 8 doi:10.1063/1.3533798.
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Gavella, M., Kveder, M. & Lipovac, V. (2010) Modulation of ROS production in human leukocytes by ganglioside micelles. Brazilian journal of medical and biological research, 43 (10), 942-949 doi:10.1590/S0100-879X2010007500092.
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Kveder, M., Merunka, D., Jokić, M., Makarević, J. & Rakvin, B. (2009) Electron spin-lattice relaxation in solid ethanol: the effect of nitroxyl radical hydrogen bonding and matrix disorder. Physical Review B - Condensed Matter and Materials Physics, 80 (5), 052201-1 doi:10.1103/PhysRevB.80.052201.
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Kveder, M., Merunka, D., Jokić, M. & Rakvin, B. (2008) EPR study of crystalline and glassy ethanol. Journal of Non-Crystalline Solids, 354 (47-51), 5201-5203 doi:10.1016/j.jnoncrysol.2008.05.062.
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Kveder, M., Merunka, D., Jokić, M. & Rakvin, B. (2008) Low temperature electron-spin relaxation in the crystalline and glassy states of solid ethanol. Physical Review B, 77 (9), 094202-1 doi:10.1103/PhysRevB.77.094202.
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Gavella, M., Kveder, M., Lipovac, V., Jurašin, D. & Filipović-Vinceković, N. (2007) Antioxidant properties of ganglioside micelles. Free Radical Research, 41 (10), 1143-1150 doi:10.1080/10715760701618245.
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Kveder, M., Andreis, M., Makarević, J., Jokić, M. & Rakvin, B. (2006) EPR study of low molecular weight organogels by means of a nitroxide spin probe. Chemical Physics Letters, 420 (4-6), 443-447 doi:10.1016/j.cplett.2006.01.010.
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Kveder, M., Marinić, Ž., Kriško, A., Vikić-Topić, D. & Pifat, G. (2006) Lipid-Protein Interactions in Human Plasma LDL Evidenced by Magnetic Resonance. Chemistry and Physics of Lipids, 141 (1-2), 225-229 doi:10.1016/j.chemphyslip.2006.02.014.
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Kveder, M., Merunka, D., Ilakovac, A., Makarević, J., Jokić, M. & Rakvin, B. (2006) Direct evidence for the glass-crystalline transformation in solid ethanol by means of a nitroxide spin probe. Chemical Physics Letters, 419, 91-95 doi:10.1016/j.cplett.2005.11.055.
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Kriško, A., Piantanida, I., Kveder, M., Pifat, G., Lee, A., Greilberger, J., Kipmen-Korgun, D. & Jürgens, G. (2006) The effect of heparin on structural and functional properties of low density lipoproteins. Biophysical chemistry, 119, 234-239 doi:10.1016/j.bpc.2005.09.011.
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Gavella, M., Kveder, M., Lipovac, V., Rakoš, R. & Pifat, G. (2005) Trisialoganglioside GT1b prevents increase in sperm membrane molecular ordering induced by in vitro lipid peroxidation. Journal of andrology, 26 (6), 724-731 doi:10.2164/jandrol.05038.
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Kriško, A., Kveder, M. & Pifat, G. (2005) Effect of caffeine on oxidation susceptibility of human plasma low density lipoproteins. Clinica chimica acta, 355 (1-2), 47-53 doi:10.1016/j.cccn.2004.12.001.
doi Kriško, A., Kveder, M., Pečar, S. & Pifat, G. (2005) The study of caffeine binding to human serum albumin. Croatica chemica acta, 78, 71-77.
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Kveder, M., Rakoš, R., Gavella, M., Lipovac, V., Pifat, G., Pečar, S. & Schara, M. (2004) EPR Investigation of Cell Membrane Fluidity upon External Oxidative Stimulus. Applied magnetic resonance, 27 (1-2), 77-86 doi:10.1007/BF03166303.
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Kriško, A., Piantanida, I., Kveder, M. & Pifat, G. (2004) The analysis of beta-carotene absorbance for studying structural properties of human plasma low density lipoproteins. Analytical biochemistry, 331 (1), 177-182 doi:10.1016/j.ab.2004.03.048.
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Carić, D., Tomišić, V., Kveder, M., Galić, N., Pifat, G., Magnus, V. & Šoškić, M. (2004) Absorption and fluorescence spectra of ring-substituted indole-3-acetic acids. Biophysical chemistry, 111 (3), 247-257 doi:10.1016/j.bpc.2004.06.006.
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Kveder, M., Kriško, A., Pifat, G. & Steinhoff, H. (2003) The study of structural accessibility of free thiol groups in human low-density lipoproteins. Biochimica et Biophysica Acta, 1631 (3), 239-245 doi:10.1016/S1388-1981(03)00022-2.
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Kveder, M., Pifat, G., Gavella, M. & Lipovac, V. (2003) Effect of gangliosides on the copper-induced oxidation of human low-density lipoproteins. Biophysical chemistry, 104 (1), 45-54 doi:10.1016/S0301-4622(02)00337-X.
doi Schara, M., Nemec, M., Falnoga, I., Kobal, A., Kveder, M. & Svetek, J. (2001) The action of mercury on cell membranes. Cellular & molecular biology letters, 6, 299-304.
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Brnjas-Kraljević, J., Kveder, M., Pifat, G., Pečar, S. & Schara, M. (2001) The ESR kinetic study of lipid phase in HDL. Croatica chemica acta, 74 (1), 147-160.
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Antolić, S., Kveder, M., Klaić, B., Magnus, V. & Kojić-Prodić, B. (2001) Recognition of the folded conformation of plant hormone (auxin, IAA) conjugates with glutamic and aspartic acids and their amides. Journal of molecular structure, 560 (1-3), 223-237 doi:10.1016/S0022-2860(00)00771-7.
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Kveder, M., Pifat, G., Vukelić, B., Pečar, S. & Schara, M. (2000) Structural aspects of thiol-specific spin labeling of human plasma low density lipoprotein. Biopolymers, 57 (6), 336-343 doi:10.1002/1097-0282(2000)57:63.0.CO ; 2-1.
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Vass, E., Hollosi, M., Kveder, M., Kojić-Prodić, B., Čudić, M. & Horvat, Š. (2000) Spectroscopic evidence of beta-turn in N-glycated peptidomimetics related to leucine-enkephalin. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 56 (12), 2479-2489 doi:10.1016/S1386-1425(00)00336-X.
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Kveder, M., Pifat, G., Jelovečki, A., Klaić, B., Pečar, S. & Schara, M. (2000) EPR study of LDL perturbed by alcohols with different molecular architecture. Alcohol, 21 (2), 141-147 doi:10.1016/S0741-8329(00)00082-3.
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Kojić-Prodić, B., Antolić, S., Kveder, M., Žigrović, I., Kidrič, J. & Horvat, Š. (1999) Conformational studies in solid state and solution of protected C-terminal dipeptide fragment (Boc-Phe-Pro-HN2) of morphiceptin. Croatica chemica acta, 72 (2-3), 259-277.
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Kveder, M., Šentjurc, M. & Schara, M. (1998) Spin probe reduction in cells and tissues. Magnetic resonance in medicine, 8 (3), 241-247 doi:10.1002/mrm.1910080302.
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Kveder, M., Pifat, G., Pečar, S. & Schara, M. (1998) The influence of lower alcohols on the surface lipid monolayer in LDL. Croatica chemica acta, 71 (1), 189-198.
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Kveder, M., Pifat-Mrzljak, G., Pečar, S., Schara, M., Ramos, P. & Esterbauer, H. (1997) Nitroxide reduction with ascorbic acid in spin labeled human plasma LDL and VLDL. Chemistry and physics of lipids, 85 (1), 1-12 doi:10.1016/S0009-3084(96)02636-9.
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Kveder, M., Pifat-Mrzljak, G., Pečar, S., Schara, M., Ramos, P. & Esterbauer, H. (1997) The interaction of lower alcohols with apoB in spin labeled human plasma low density lipoproteins (LDL). Chemistry and physics of lipids, 87 (2), 125-135 doi:10.1016/S0009-3084(97)00035-2.
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Lassen, D., Lucke, C., Kveder, Marina, Mesgarzadeh, A., Schmidt, J., Specht, B., Lezius, A., Spener, F. & Ruterjans, H. (1995) Three‐Dimensional Structure of Bovine Heart Fatty‐acid‐binding Protein with Bound Palmitic Acid, Determined by Multidimensional NMR Spectroscopy. European Journal of Biochemistry, 230 (1), 266-280 doi:10.1111/j.1432-1033.1995.0266i.x.
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Kveder, M., Pifat, G. & Pečar, Slavko, Schara, Milan (1994) The ESR characterization of molecular mobility in the lipid surface-layer of human serum-lipoproteins. Chemistry and Physics of Lipids, 70 (1), 101-108 doi:10.1016/0009-3084(94)90052-3.
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Kveder, M., Pifat Mrzljak, G., Pečar, S. & Schara, M. (1992) Molecular-dynamics of surface lipids in human serum lipoproteins studied by ESR. Croatica Chemica Acta, 65 (1), 201-209.
hrcak.srce.hr Kveder, M., Pecar, S., Nemec, M. & Schara, M. (1991) Nitroxide radicals as a model system for biotransformations of radicals in tissues. Acta pharmaceutica Iugoslavica, 41, 391-400.
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Demsar, F., Kveder, M., Rugelj, S., Blinc, A., Šentjurc, M. & Pečar, S. (1991) Hydroxylamines as oxygen-sensitive procontrast agents for in vivo magnetic resonance imaging. Journal of magnetic resonance (San Diego, Calif.), 95 (2), 281-285 doi:10.1016/0022-2364(91)90218-I.
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Kveder, M., Lahajnar, G., Blinc, R. & Zupančič, I. (1988) Non-Brownian water self-diffusion in lung tissue. Magnetic resonance in medicine, 6 (2), 194-198 doi:10.1002/mrm.1910060207.
doi Sentjurc, M., Schara, M., Auersperg, M., Jezernik, M. & kveder, M. (1988) Characterization of malignant tissues by EPR. Studia biophysica, 136, 201-208.
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Kveder, M., Bajzer, Ž. & Zadro, M. (1987) Theoretical aspects of multiple deconvolution analysis for quantification of left to right cardiac shunts. Physics in medicine and biology, 32 (10), 1237-1243 doi:10.1088/0031-9155/32/10/003.
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Kveder, M., Bajzer, Ž. & Nosil, J. (1985) A mathematical model for the quantitative study of left to right cardiac shunt. Physics in medicine and biology, 30 (3), 207-215 doi:10.1088/0031-9155/30/3/001.
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Članstva u profesionalnim udrugama / društvima
Croatian Society for Biophysics
Croatian Physical Society
Croatian Humboldt Club
Croatian-Austrian Society
Neposredno pridonijela sa cca. 120.000 USD u nabavci znastvene opreme u IRB/LMR (Alexander von Humboldt donacija za EPR instrumentaciju i participacija za nabavku fluorimetra i spektrofotometra iz sredstava NIH projekta).