Multiplex is a project gathering together the prominent research institution at the intersection within Network Science, Complex Systems. Algorithms, Statistical Physics and so forth. The main aim of this project is oriented to use the mathematical framework of Complex Networks and Algorithmics to establish a theoretical basis for the understanding, prediction and possibly control of the Complex Systems. This would be obtained by reconstructing their Dynamics from the huge and heterogeneous datasets available at different levels. The methods used will be derived from the approach developed in Graph Theory, Algorithmics and Statistical Physics. Validated Models will also be proposed.