David Matthew Smith

David Matthew Smith

Dr.

Senior Scientist
Divisional Head
+385 1 456 1182

1382

+385 1 456 1182

Krilo 6/203

Division of Physical Chemistry
Ruder Boskovic Institute
Bijenička cesta 54, P.P. 180,
HR-10002 Zagreb
Croatia

CV__Pubs_DMS_May16.pdf 246.59 kB

Education

  • 01.96. – 03.00. PhD at the Research School of Chemistry, Australian National University, Canberra, ACT, Australia. Supervisor: Professor Leo Radom  Thesis : Theoretical Studies of Coenzyme-B12-Dependent Reactions. Deans Prize for the best thesis in Chemistry at the Australian National University in 2000.
  • 03.95. – 11.95. Awarded first class honours in chemistry from the Department of Chemistry, Australian National University. Supervisor: Dr. Gad Fischer Thesis: An Ab Initio Study of the Electronic Spectrum of the Triazine Molecules
  • 03.91. – 11.94. BSc (Bachelor of Science), Australian National University, Canberra, Australia.
  • 03.91. – 11.94. BEc (Bachelor of Economics), Australian National University, AU.

Projects

  • 06.15 – 09.16. Principal investigator of the project entitled "Network for professional training of young scientists in interdisciplinary research of innovative surfaces and materials", funded by the European Social Fund (ESF) and valued at 2 000 000 HRK.
  • 07.14 – 07.18. Principal investigator of the scientific research project entitled "Computational Solutions in the Life Sciences: The Importance of Molecular Flexibility", funded by the Croatian Science Foundation (CSF) and valued at 900 000 HRK.
  • 12.14 – 12.18. Mentor in a Career Development Project for Young Researchers - The Training of New Doctors of Science, financed by the Croatian Science Foundation (CSF) to cover the salary of a PhD student.
  • 10.13 – 10.15. Co-worker for a project within the Research Cooperability, Crossing Borders Programme, entitled "Time resolved photoelectron spectroscopy as a probe for ultrafast excited state dynamics", funded by the Unity through Knowledge Fund (UKF) and valued at 185 000 EUR.
  • 09.13 – 09.16 Project Manager and Work Package leader of a project within the Seventh Framework Programme, entitled "InnoMol" (FP7- REGPOT-2012-2013-1) valued at 4.7 million EUR.
  • 10.10. – 10.13. Co-investigator of a project within the Research Group Linkage Programme, entitled "Computational Life Sciences on Open Shell Intermediates", funded by the Alexander von Humboldt Foundation (AvH) and valued at 50 000 EUR for a period of three years.
  • 04.07 – 04.10. Coordinator of a project within the Sixth Framework Programme, entitled "Reinforcement of the Centre for Computational Solutions in the Life Sciences" (EU-FP6-043749-ReCompSoLS), funded by the European Commission and valued at 380 000 EUR for a period of three years.
  • 01.07 –. Principle investigator of the scientific research project entitled "Computational Studies of Protein Structure and Function" (098-0982933-2937), funded by the Ministry of Science, Education and Sport of the Republic of Croatia and valued at 90 000 HRK per year.
  • 04.05 –.12.06. Principle investigator of the scientific research project entitled "Computational Studies of Protein Structure and Function" (0098151), funded by the Ministry of Science, Education and Sport of the Republic of Croatia and valued at 30 000 HRK per year.

Awards and Achievements

  • 11.08. Recipient of the 2008 Lavoslav (Leopold) Ruzicka Award of the Croatian Chemical Society for Young Scientists
  • 04.04. – 04.05. Return Fellowship for Research Fellows of the Alexander von Humboldt Foundation in Central and Eastern Europe to be carried out at the Ruđer Bošković Institute, Zagreb, Croatia
  • 01.05. Recipient of an equipment donation from the Alexander von Humboldt Foundation in the form of a computer cluster valued at 20 000 EUR.
  • 11.03. – 02.04. Postdoctoral Fellowship from the DFG (German Research Organization) to work at the Department of Chemistry, Ludwig-Maximilians-University, Munich, Germany
  • 03.02. – 10.03., Research Fellowship from the Alexander von Humboldt Foundation (AvH) carried out at the Department of Chemistry, Ludwig-Maximilians-University, Munich, Germany
  • 04.01. Winner of the Dean’s Prize in Chemistry for the best PhD thesis in 2000 at the Research School of Chemistry, Australian National University, Canberra, Australia.
  • 01.96. – 09.99. Australian Postgraduate Award for PhD students
  • 05.97. – 07.97.Partnerships for Excellence: British Council Postgraduate Bursary to collaborate with Professor Bernard Golding at the Department of Chemistry, University of Newcastle upon Tyne, England
  • 03.95. – 11.95. Research School of Chemistry Honours Year Scholarship for talented students
  • 12.94. – 03.95. Research School of Chemistry Summer Research Scholarship

Classes

  • 11.11. – Lecturer for the Masters level course: Computational Chemistry as part of the curriculum of Medicinal Chemistry at the University of Rijeka, Croatia.
  • 09.07. and 09.09 Presenter of “hands-on” practical computational sessions in Molecular Dynamics and QM/MM Calculations at conferences in Opatija and Primošten (see organized conferences below)
  • 03.95. – 10.98. Teaching assistant, Course: Chemistry A11 (introductory course for first-year students), Department of Chemistry, Australian National University.
  • 03.95 – 10.97. Personal tutor for numerous high school students in the areas of Chemistry, Mathematics, Physics, and Economics.

Featured Publications

Smith, D. M.; Golding, B. T.; Radom*, L. J. Am. Chem. Soc. 121 (1999), 9388-9399. Understanding the Mechanism of B12-Dependent Methlymalonyl-CoA Mutase: Partial-Proton-Transfer in Action.

Smith, D. M.; Golding, B. T.; Radom*, L. J. Am. Chem. Soc. 123 (2001), 1664-1675. Understanding the Mechanism of B12-Dependent Diol Dehydratase: A Synergistic Retro-Push-Pull Proposal.

Smith, D. M.; Buckel, W.; Zipse*, H. Angew. Chem. Int. Ed. 42 (2003), 1867-1870. Enhanced Acidity of Enoxy Radicals: Theoretical Validation of a 50 Year Old Mechanistic Proposal.

Čondić-Jurkić, K.; Perchyonok, V. T.; Zipse, H.; Smith*, D. M. J. Comput. Chem. 29 (2008), 2425–2433. On the Modeling of Arginine-Bound Carboxylates: A Case Study with Pyruvate Formate-Lyase.

Sandala*, G. M.; Smith*, D. M.; Radom*, L. Acc. Chem. Res. 43 (2010), 642-651. Modeling the Reactions Catalyzed by Coenzyme B12 Dependent Enzymes.

Bucher*, D.; Sandala*, G. M.; Durbeej, B.; Radom*, L.; Smith*, D. M. J. Am. Chem. Soc. 134 (2012), 1591-1599.  The Elusive 5'-Deoxyadenosyl Radical in Coenzyme-B12-Mediated Reactions.

Dragičević, I.; Barić*, D.; Kovačević, B.; Golding, B. T.; Smith*, D. M. Chem. Eur. J. 21 (2015), 6132-6143. Non-enzymatic Ribonucleotide Reduction in the Prebiotic Context.

Membership in professional associations / societies

  • 05. –                Member of the American Chemical Society.
  • 04. –                Member of the World Association of Theoretically Oriented Chemists.
  • 04. –                Member of the Croatian Chemical Society
  • 96. – 03.           Member of the Royal Australian Chemical Institute.

Miscellaneous

WORK EXPERIENCE AS INDEPENDENT RESEARCHER

06.16 – Divisional Head and Senior Scientist in the Division of Physical Chemistry at the Ruđer Bošković Institute in Zagreb, Croatia

03.16 – 05.16. Acting Head and Senior Scientist in the Division of Physical Chemistry at the Ruđer Bošković Institute in Zagreb, Croatia

02.14 – 02.16  Senior Scientist in the Division of Organic Chemistry and Biochemistry at the Ruđer Bošković Institute in Zagreb, Croatia

10.09 – 01.14  Assistant Director of the Ruđer Bošković Institute, responsible for International Collaboration and Projects

09.08. – 02.16. Group Leader of the Group for Quantum Organic Chemistry at the Division of Organic Chemistry and Biochemistry at the Ruđer Bošković Institute in Zagreb, Croatia

02.08. –  Senior Research Associate in the Division of Organic Chemistry and Biochemistry at the Ruđer Bošković Institute in Zagreb, Croatia

03.04. – 02.08 Research Associate in the Division of Organic Chemistry and Biochemistry at the Ruđer Bošković Institute in Zagreb, Croatia

POSTDOCTORAL EXPERIENCE

10.01. – 01.03.  Alexander von Humboldt/Postdoctoral Fellowship in the Quantum

06.03. – 02.04.  Chemistry Group at the Department of Chemistry, Ludwig-Maximilians-University, Munich, Germany. Project Leader: Professor H. Zipse.

04.00 – 08.01. Postdoctoral Fellowship in the Quantum Chemistry Group at the Institute Ruđer Bošković, Zagreb, Croatia. Project Leader: Professor Z. B. Maksić

PROFESSIONAL EXCHANGE

01.14. – 09.14. Sabbatical Stay at the Excellence Cluster: Engineering of Advanced Materials, Universität Erlangen-Nürnberg, Germany

10.09. –  Visiting Professorship at the Excellence Cluster: Engineering of Advanced Materials, Universität Erlangen-Nürnberg, Germany

10.08. – 12.08.  Visiting Fellowship at the School of Chemistry, University of Sydney, Sydney, Australia

04.08. – 05.08.  Visiting Fellowship at the School of Chemistry, University of Sydney, Sydney, Australia

02.05. – 05.05.  Visiting Fellowship at the School of Chemistry, University of Sydney, Sydney, Australia

02.03. – 05.03.  Visiting Fellowship at the Research School of Chemistry, Australian National University, Canberra, Australia

05.97. – 07.97. Partnerships for Excellence: British Council Postgraduate Bursary to collaborate with Professor Bernard Golding at the Department of Chemistry, University of Newcastle upon Tyne, England