Lipa Čičin-Šain

Lipa Čičin-Šain

Dr. sc.

Senior scientist
+385 1 456 1045


Krilo 4/11B

Laboratory of Neurochemistry and Molecular Biology, Department of Molecular Biology,
Rudjer Boškovic Institute, Bijenicka 54, HR-10000 Zagreb, Croatia



1981. Faculty of Natural Sciences, University of Zagreb, BSc in Biology

1984. Faculty of Natural Sciences, University of Zagreb, MSc in Experimental Biology

1988. University of Zagreb, PhD in Neurobiology

1990. King's College, London, postdoctoral fellow


"Serotonergic mechanisms in alcoholism", Ministry of Science, Education and Sport, Republic of Croatia, 2007-


"Animal models in biological psychiatry", doctoral study in Neuroscience, Medical Faculty, University of Zagreb

"Saturation kinetics of synaptic enzymes, transporter and receptors", doctoral study in Neuroscience, Medical Faculty, University of Zagreb

Featured Publications


Cicin-Sain L, Jernej B. Wistar-Zagreb 5HT rats: A rodent model with constitutional upregulation/downregulation of serotonin transporter. In: AV Kalueff, J Laporte (ed) Experimental models in serotonin transporter research, Cambridge University Press, 2010, Cambridge, pp 214-243

Bordukalo-Niksic T, Mokrovic G, Stefulj J, Zivin M, Jernej B, Cicin-Sain L. 5HT-1A receptors and anxiety-like behaviours: studies in rats with constitutionally upregulated / downregulated serotonin transporter. Behavioral Brain Research 213(2010)238-245.

Banović M, Bordukalo-Niksic T, Balija M, Cicin-Sain L, Jernej B Kinetics of platelet serotonin transporter (5HTt): study of physiological characteristics on a large human population. Platelets 21 (2010) 429-438  

Hranilovic D, Bujas-Petkovic Z, Tomičić M, Bordukalo-Niksic T, Blazevic S, Cicin-Sain L. Hyperserotoninemia in autism: activity of 5HT-associated platelet proteins. J Neural Transmission (2009) 493-501

Cicin-Sain L, Simaga S, Froebe A, Abramic M. Central aminopeptidase and serotonin system activities:possible relationship. Neuropeptides 42 (2008) 435-440.

Cicin-Sain L, Matosic A, Mokrovic G, Balija M, Marusic S, Jernej B. Platelet monoamine oxidase kinetics, alcoholism subtypes and cigarette smoking. Neuropsychobiology 56 (2007) 138-145.

Hranilovic D, Cicin-Sain L, Bordukalo-Niksic T, Jernej B. Rats with constitutionally upregulated/downregulated platelet 5HT transporter: differences in anxiety-related behavior. Behav Brain Res 165 (2005) 271-277.

Cicin-Sain L, Froebe A, Bordukalo-Niksic T, Jernej B. Serotonin transporter kinetics in rats selected for extreme values of platelet serotonin level. Life Sciences 77 (2005) 452-461.

Bordukalo-Niksic T, Cicin-Sain L, Jernej B. Expression of brain and platelet serotonin transporters in sublines of rats with constitutionally altered serotonin homeostasis. Neurosci Lett 369 (2004) 44-49.

Cicin-Sain L, Mimica N, Hranilovic D, Balija M, Ljubin T, Makaric G, Folnegovic-Smalc V, Jernej B. Posttraumatic stress disorder and platelet serotonin measures. J Psychiat Res 34 (2000) 155-161.

Jernej B, Froebe A, Hranilovic D, Cicin-Sain L. Platelet serotonin transporter: ex vivo monitoring of kinetic parameters in the individual rat. Neurosci Res Comm 24 (1999) 163-172.

Cicin-Sain L, Froebe A, Jernej B. Physiological characteristics of serotonin transporter on rat platelets. Comp Biochem Phys A 120 (1998) 723-729.

Romero L, Jernej B, Bel N, Cicin-Sain L, Cortes R, Artigas F. Basal and stimulated extracellular serotonin concentration in the brain of rats with altered serotonin uptake. Synapse 28 (1998) 313-321.

Jernej B, Cicin-Sain L. Platelet serotonin level in rats is under genetic control. Psychiat Res 32 (1990) 167-174

Membership in professional associations / societies

Croatian Biological Society, Croatian Pharmacological Society; Croatian Society for

Neuroscience, Serotonin Club - International Group of Biomedical Scientists (1990- ), The

Federation of European Pharmacological Societies (EPHAR), International Union of Basic and

Clinical Pharmacology (IUPHAR)