Ana Čipak Gašparović

PhD

senior research associate
+385 1 456 1017

1520
1705

Biologija 2/19

Ruđer Bošković Institute
Bijenička cesta 54
10000 Zagreb
Croatia

Education

  • October, 1996. – April, 2001. – Molecular biology, Faculty of Natural Sciences in Zagreb (2nd April 2001. – Diploma thesis – "Effects of 4-hydroxynonenal on rat liver cells dr.sc. Neven Žarković)
  • October 2001. – University  of Salzburg
  • September – October, 2002. – Karl-Franzens University, Graz
  • June 2003. – Karl-Franzens University, Graz
  • June 2004. – Karl-Franzens University, Graz
  • September - October 2004 - University of New South Wales, Sydney, Australia
  • September 2005 - Karl-Franzens University, Graz
  • September – October, 2006 - Karl-Franzens University, Graz
  • since 2008 - specialist studies in project management, joint study of the Rudjer Boskovic Institute and the College for business and management «Baltazar Adam Krcelic» – master study
  • June 2009, PhD thesis "Saccharomyces cerevisiae as a novel model in lipid peroxidation research", Faculty of Natural Sciences in Zagreb  Neven Žarković)

Projects

Croatian-Austrian bilateral project: "Effects of oxidatively modified collagen on breast cancer stem cell growth and differentiation"(Austrian partner:dr.uni.med. Marija Balic University Clinic of Internal Medicine, Graz)

Classes

  • Associate on ‘Cell and tissue culture for biomedicine researches’ – University of Osijek, Rudjer Boskovic Institute and University of Dubrovnik – PhD Program - Molecular Biosciences
  • Associate on 'Experimental oncology: persistent oxidative stress in malignant diseases' – Medical Faculty, University of Zagreb – PhD Program
  • 'Oxidative stress in carcinogenesis – models and methods' – University of Osijek, Rudjer Boskovic Institute and University of Dubrovnik – PhD Program - Molecular Biosciences

Featured Publications

  1. Cipak A, Hasslacher M, Tehlivets O, Collinson EJ, Zivkovic M, Matijevic T, Wonisch W, Waeg G, Dawes IW, Zarkovic N, Kohlwein SD. Saccharomyces cerevisiae strain expressing a plant fatty acid desaturase produces polyunsaturated fatty acids and is susceptible to oxidative stress induced by lipid peroxidation. Free Radical Biology and Medicine 40 (5) (2006), 897-906.
  2. Čipak A, Jaganjac M, Tehlivets O, Kohlwein SD, Žarković N. Adaptation to oxidative stress induced by polyunsaturated fatty acids in yeast. Biochimica et Biophysica Acta 1781 (2008); 283-287.
  3. Marquez-Quiñones A, Čipak Gašparović A, Žarković K, Fattel-Fazenda S, Villa-Treviño S, Waeg G, Žarković N, Gueraud F, HNE-protein adducts formation in different pre-carcinogenic stages of hepatitis in LEC rats, Free Radical Research (2010), 44(2):119-127.
  4. Custovic Z, Zarkovic K, Cindric M, Cipak A, Jurkovic I, Sonicki Z, Uchida K, Zarkovic N, Lipid peroxidation product acrolein as predictive biomarker of prostate carcinoma relapse after radical surgery, Free Radical Research 2010;44(5):497-504.
  5. Augustyniak A, Bartosz G, Čipak A, Duburs A, Horáková L, Łuczaj W, Majekova M, Odysseos AD, Rackova L, Skrzydlewska E, Stefek M, Štrosová M, Tirzitis G, Rimantas Venskutonis P, Viskupicova J, Vraka PS, Žarković N, Natural and synthetic antioxidants – an updated overview, Free Radical Research, 2010, 44(10):1216-1262. pregledni članak.
  6. Gueraud F, Atalay M, Bresgen N, Čipak A, Eckl PM, Huc L, Jouanin I, Siem W, Uchida K, Chemistry and biochemistry of lipid peroxidation products Free Radical Research, 2010, 44(10):1098-1124. pregledni članak.
  7. Cipak A, Mrakovcic L, Ciz M, Lojek A, Mihaylova B, Goshev I, Jaganjac M, Cindric M, Sitic S, Margaritoni M, Waeg G, Balic M, Zarkovic N, Growth suppression of human breast carcinoma stem cells by lipid peroxidation product 4-hydroxy-2-nonenal and hydroxyl radical-modified collagen Acta Biochimica Polonica, 2010, 52(2):165-171.
  8. Cipak A, Borovic S, Jaganjac M, Bresgen N, Kirac I, Grbesa I, Mrakovcic L, Cindric M, Scukanec-Spoljar M, Gall-Troselj K, Coric M, Eckl P, Zarkovic N, Influence of 4-hydroxynonenal and spleen cells on primary hepatocyte culture and a novel liver-derived cell line resembling hepatocyte stem cells Acta Biochimica Polonica, 2010, 52(2): 185-191.
  9. Cindric M, Cipak A, Serly J, Plotniece A, JaganjacM, Mrakovcic L, Lovakovic T, Dedic A, Soldo I, Duburs G, Zarkovic N,  Joseph Molnar, Reversal of multidrug resistance in murine lymphoma cells by amphiphilic dihydropyridine antioxidant derivative enhancing anticancer effects of doxorubicin, Anticancer Research, 2010 (30): 4063-407.

Membership in professional associations / societies

  • Croatian Association for Cancer Research (CACR)
  • Croatian Society for Biochemistry and Molecular Biology (HDBMB)
  • Society for Free Radical Research (SFRR)
  • The International HNE-Club
  • COST B35 Action
  • COST TD0901 HypoxiaNet Action

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