Laboratory for Personalized Medicine

Laboratory for Personalized Medicine

Research conducted in the LPMed involves the study of molecular and genetic mechanisms underlaying colorectal cancer development and progression as well as pharmacogenetic studies associated with the effectivness and toxicity of cancer therapies.

Head

MD, PhD Sanja Kapitanović

+385 1 456 1108
Fax: +385 1 456 1010
left right

LPMed staff has a long record of research in the field of colorectal cancer tumorigenesis. Since colorectal cancer is by incidence one of the most common cancers in Croatia as well as worldwide this laboratory is an important constituent of the Cancer Research Programme at the IRB.

LPMed has over the years acquired a substantial amount of tumour samples from Croatian patients suffering from sporadic colorectal cancer and has a good collaboration with clinics. These samples are part of the Croatian Tumour and DNA bank at the Department for Molecular Medicine.

In addition, LPMed offers the service of molecular testing for hereditary gastrointestinal cancer (FAP, HNPCC), hereditary and somatic pharmacogenetic markers as well as for the neurofibromatosis type I.

Emilija Zapletal
PhD

senior assistant
+385 1 457 1383
1557 1731

Sanja Kapitanović
MD, PhD

Senior Scientist
+385 1 456 1108
1611 1508

Tamara Čačev
PhD, MBA

Senior research associate
+385 1 457 1383
1557

Tanja Matijević Glavan
PhD

senior assistant
+385 1 457 1384
1558

Tina Catela Ivković
B.Sc.

Assistant, PhD student
+385 1 456 1108
1508

Microsatellite instability (MSI and EMAST) in molecular profiling of sporadic colon cancer (MSIandEMASTinCRC)

Glavni istraživač / voditelj: Sanja Kapitanović

The main goal of this project is to investigate MSI and EMAST microsatellite instability in sporadic colon cancer and to correlate the obtained results with clinico-pathological characteristics of tumors and patients.

more »

Molecular genetics and pharmacogenetics of gastrointestinal tumors

Glavni istraživač / voditelj: Sanja Kapitanović

The main goal of this study is to investigate hereditary and sporadic genetic changes in benign and malignant gastrointestinal tumors in order to elucidate the mechanisms of their development and progression. Another goal of this study is to start with prospective pharmacogenetic study in order to examine the correlation between known polymorpisms and gastrointestinal cancer therapy.

more »
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