Dr. Maja Kesić
Bijenička 54
HR-10000 Zagreb
Education
- 2016: PhD in biology, Faculty of Science, University of Zagreb, Croatia
- 2009: BSc in Molecular Biology, Faculty of Science, University of Zagreb, Croatia
- 2009: Profesor of Biology and Chemistry, Faculty of Science, University of Zagreb, Croatia
Awards and Achievements
- 2013. - Stipend awarded by Austrian Pharmacological Society (APHAR) for attending: 18th Scientific Symposium of the APHAR, Joint Meeting with the Croatian, Serbian and Slovenian Pharmacological Societies, Graz, Austria
- 2011. – Stipend awarded by Croatian Neuroscience Society for attending SNC´11, Central European FENS Featured Regional Meeting, Ljubljana, Slovenia
Classes
- Biological Psychology I (leader: J. Štefulja), BSc study in Psychology, Croatian Catholic University (2012/2013, 2013/2014)
- Biomembranes (leader: M. Ilakovac Kveder), study of Molecular Biology, Faculty of Sciences, University of Zagreb (2010/11, 2011/2012)
- Biophysic of the cell (leader: M. Ilakovac Kveder), study of Chemistry, Faculty of Sciences, University of Zagreb (2010/2011)
Featured Publications
Blažević SA, Horvatiček M, Kesić M, Zill P, Hranilović D, Ivanišević M, Desoye G, Štefulj J (2017) Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus. PLoS ONE 12(6): e0179934. https://doi.org/10.1371/journal.pone.0179934
Erjavec I, Bordukalo-Nikšić T, Brkljačić J, Grčević D, Mokrović G,Kesić M, Rogić D, Zavadoski W, Paralkar V, Grgurević L, Trkulja V, Čičin-Šain L, Vukičević S (2016) Constitutively elevated blood serotonin is associated with bone loss and type 2 diabetes in rats. PLoS One. 11(2);e0150102. Doi: 10.1371/journal.pone.0150102. eCollection 2016.
Kesić M, Tvrdeić A, Kolarić D, Stojković R, Čičin-Šain L (2015)Serotonergic modulation of pain and analgesic responses: A study in rats with constitutionally altered serotonin transporters. Eur J Pain 19: 508-15
Publications - journal articles
Izvorni znanstveni rad
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Kesić, Maja ; Baković, Petra ; Farkaš, Vladimir ; Bagarić, Robert ; Kolarić, Darko ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Constitutive Serotonin Tone as a Modulator of Brown Adipose Tissue Thermogenesis: A Rat Study // Life, 13 (2023), 7; 1436, 21. doi: 10.3390/life13071436
doiwww.mdpi.com -
Baković, Petra ; Kesić, Maja ; Kolarić, Darko ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Metabolic and Molecular Response to High-Fat Diet Differs between Rats with Constitutionally High and Low Serotonin Tone // International journal of molecular sciences, 24 (2023), 3; 2169, 23. doi: 10.3390/ijms24032169
doiwww.mdpi.comfulir.irb.hr -
Horvatiček, Marina ; Perić, Maja ; Bečeheli, Ivona ; Klasić, Marija ; Žutić, Maja ; Kesić, Maja ; Desoye, Gernot ; Nakić Radoš, Sandra ; Ivanišević, Marina ; Hranilovic, Dubravka et al. | Maternal Metabolic State and Fetal Sex and Genotype Modulate Methylation of the Serotonin Receptor Type 2A Gene (HTR2A) in the Human Placenta // Biomedicines, 10 (2022), 2; 467, 19. doi: 10.3390/biomedicines10020467
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Kesić, Maja ; Mokrović, Gordana ; Tvrdeić, Ante ; Miše, Branko ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Constitutive serotonin tone modulates molecular and behavioral response to chronic fluoxetine treatment: a study on genetic rat model // Frontiers in psychiatry, 12 (2021), 741222, 12. doi: 10.3389/fpsyt.2021.741222
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Baković, Petra ; Kesić, Maja ; Perić, Maja ; Bečeheli, Ivona ; Horvatiček, Marina ; George, Meekha ; Čičin-Šain, Lipa ; Desoye, Gernot ; Wadsack, Christian ; Panzenboeck, Ute et al. | Differential Serotonin Uptake Mechanisms at the Human Maternal–Fetal Interface // International journal of molecular sciences, 22 (2021), 15; 7807, 17. doi: 10.3390/ijms22157807
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Kesić, Maja ; Baković, Petra ; Stojković, Ranko ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Metabolic disturbances in rat sublines with constitutionally altered serotonin homeostasis // International journal of molecular sciences, 22 (2021), 10; 5400, 20. doi: 10.3390/ijms22105400
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Kesić, Maja ; Baković, Petra ; Horvatiček, Marina ; Proust, Bastien Lucien Jean ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis // Frontiers in neuroscience, 14 (2020), 219, 14. doi: 10.3389/fnins.2020.00219
doiwww.frontiersin.orgfulir.irb.hr -
Blažević, Sofia Ana ; Horvatiček, Marina ; Kesić, Maja ; Zill, Peter ; Hranilović, Dubravka ; Ivanišević, Marina ; Desoye, Gernot ; Štefulj, Jasminka | Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus // PLoS One, 12 (2017), 6; e0179934-e0179934. doi: 10.1371/journal.pone.0179934
doijournals.plos.orgwww.ncbi.nlm.nih.govfulir.irb.hr -
Erjavec, Igor ; Bordukalo-Nikšić, Tatjana ; Brkljačić, Jelena ; Grčević, Danka ; Mokrović, Gordana ; Kesić, Maja ; Rogić, Dunja ; Zavadoski, William ; Paralkar, Vishwas ; Grgurević, Lovorka et al. | Constitutively elevated blood serotonin is associated with bone loss and type 2 diabetes in rats // PLoS One, 11 (2016), 2; 0150102-0150102. doi: 10.1371/journal.pone.0150102
doijournals.plos.orgwww.ncbi.nlm.nih.gov -
Kesić, Maja ; Tvrdeić, Ante ; Kolarić, Darko ; Stojković, Ranko ; Čičin-Šain, Lipa | Serotonergic modulation of pain and analgesic responses : a study in rats with constitutionally altered serotonin transporters // European journal of pain, 19 (2015), 4; 508-515. doi: 10.1002/ejp.574
doionlinelibrary.wiley.com
Publications - conference proceedings
Sažetak izlaganja sa skupa
Tvrdeić, Ante ; Poljak, Ljiljana ; Miše, Branko ; Pavić, Josip ; Kesić, Maja ; Čičin-Šain, Lipa | DIFFERENCES AMONG SUBLINES OF WZ-5HT RATS IN THE EMERGENCE TEST, AUTOGROOMING AND REARING BEHAVIOUR DURING THE OPEN FIELD TEST // Abstract Book of 9th Croatian Congress of Pharmacology with International Participation. | Zagreb: Hrvatsko društvo farmakologa, 2019. str. 121-121
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Horvatiček, Marina ; Baković, Petra ; Kesić, Maja ; Kolarić, Darko ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Thermogenic and molecular response to beta-3 adrenergic receptor agonist treatment in rats with constitutionally altered serotonin homeostasis // Congress of the Croatian Society of Biochemistry and Molecular Biology "Crossroads in Life Sciences", Book of Abstract. | Zagreb: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB), 2019. str. 89-89
www.hdbmb2019.imi.hr Baković, Petra ; Kesić, Maja ; Lucien Jean Proust, Bastien ; Štefulj, Jasminka ; Čičin- Šain, Lipa | Effect of high-fat diet on glucose and lipid metabolism in rats with constitutionally altered serotonin homeostasis // Book of Abstract of the Congress of the Croatian Society of Biochemistry and Molecular Biology "Crossroads in Life Sciences". | 2019. str. 67-67
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Baković, Petra ; Kesić, Maja ; Lucien Jean Proust, Bastien ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Wistar-Zagreb serotonin (WZ-5HT) rats - a new animal model of obesity // Pokusne životinje u znanstvenim istraživanjima 2018, 3. znanstveno-stručni simpozij Hrvatskoga društva za znanost o laboratorijskim životinjama, 2. zajednički skup CroLASA-e i SLAS-a s međunarodnim sudjelovanjem : knjiga sažetaka. | 2018. str. 34-34
www.crolasa.com Baković, Petra ; Kesić, Maja ; Proust, Bastien Lucien Jean ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Functional and molecular response of rats with constitutionally altered serotonin homeostasis to high-fat diet // FEBS3+ Conference: From Molecules to Living Systems : Final Programme & Book of Abstracts. | Veszprém, 2018. str. 220-220
Kesić, Maja ; Kolarić, Darko ; Baković, Petra ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Brown adipose tissue thermogenesis: relation to constitutive differences in serotonin homeostasis // FEBS3+ Conference: From Molecules to Living Systems : Final Programme & Book of Abstracts. | Veszprém, 2018. str. 217-217
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Kesić, Maja ; Baković, Petra ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Endogenous serotonergic tone as a modulator of metabolic homeostasis and response to metabolic challenge // 19th Meeting of International Society for Serotonin Research Serotonin on the Wild Atlantic Way : Book of Abstracts. | 2018. str. 90-90
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Zandl-Lang, Martina ; Kesić, Maja ; Albrecher, Nicole Maria ; Panzenboeck, Ute ; Čičin-Šain, Lipa ; Štefulj, Jasminka | Expression of amyloid precursor protein (APP) and its processing enzymes in overweight/obese rats with altered serotonergic homeostasis // 6th Croatian Neuroscience Congress : Abstracts. | Zagreb, 2017. str. 86-86
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Tvrdeić, Ante ; Poljak, Ljiljana ; Babacanli, A ; Kesić, Maja ; Čičin-Šain Lipa | Marble burying behaviour: comparison of mice and rats // 6th Croatian Neuroscience Congress with International Participation˝ : Book of Abstracts. | Zagreb, 2017. str. 98-98
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Baković, Petra ; Štefulj, Jasminka ; Kesić, Maja ; Čičin-Šain, Lipa | Glucose dysregulation in obesity: studies in rats with constitutionally altered serotonin homeostasis // 6th Croatian Neuroscience Congress with International Participation˝ : Book of Abstracts. | Zagreb, 2017. str. 73-73
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Kesić, Maja ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Involvement of BDNF in fluoxetine-induced changes in body weight: studies in Wistar Zagreb-5HT rat model // 6th Croatian Neuroscience Congress with International Participation˝ : Book of Abstracts. | Zagreb, 2017. str. 97-97
www.hdn.hr Štefulj, Jasminka ; Blazević, Sofia Ana ; Horvatiček, Marina ; Kesić, Maja ; Ivanišević, Marina ; Hranilović, Dubravka ; Zill, Peter | Placental DNA methylation of the serotonin transporter gene is associated with maternal gestational diabetes // Game of Epigenomics conference. | Zagreb: Institut Ruđer Bošković, 2016. str. 55-56
Štefulj, Jasminka ; Kesić, Maja ; Čičin-Šain, Lipa | Expression profiling of obesity/adipogenesis- related genes in rats with altered serotonergic homeostasis // Book of Abstracts 5th Croatian Congress of Neuroscience. | 2015. str. 44-44
Kesić, Maja ; Kolarić, Darko ; Mokrović, Gordana ; Čičin-Šain, Lipa | Relationship between thermoregulation, obesity and serotonergic homeostasis: a study in Wistar-Zagreb 5HT rat model // Book of Abstracts 5th Croatian Congress of Neuroscience. | 2015. str. 50-51
Kesić, Maja ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Expression of adipokines and their receptors in brain and adipose tissue of rats with genetically altered serotonergic homeostasis // Book of Abstracts 5th Croatian Congress of Neuroscience. | 2015. str. 48-48
Kesić, Maja; Mokrović, Gordana; Čičin-Šain, Lipa | Behavioral Response on Wistar-Zagreb 5HT Model of Rats with Constitutionally Altered Serotonin Transporter // Drugi simpozij Hrvatskog društva za znanost o laboratorijskim životinjama s međunarodnim sudjelovanjem "Pokusne životinje u znanstvenim istraživanjima" : knjiga sažetaka / Bubić Špoljar, Jadranka; Erhardt, Julija; Lang Balija, Maja et al. (ur.). | Zagreb: Hrvatsko društvo za znanost o laboratorijskim životinjama, 2014. str. 58-59
Kesić, Maja ; Orešković, Darko ; Čičin-Šain, Lipa | Obesity phenotype of rats with constitutional hyperactivity of serotonin transporter // HDBMB2014 ˝The Interplay of Biomolecules˝. | Zagreb, 2014. str. 104-104
Bordukalo Nikšić, Tatjana ; Erjavec, Igor ; Brkljačić, Jelena ; Kesić, Maja ; Grčević, Danka ; Grgurević, Lovorka ; Čičin-Šain, Lipa ; Vukičević, Slobodan | Molecular mechanisms of serotonin effect on bone // 7. hrvatski kongres o osteoporozi - knjiga sažetaka. | 2013. str. 6-x
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Erjavec, Igor ; Bordukalo Nikšić, Tatjana ; Brkljačić, Jelena ; Pauk, Martina ; Grgurević, Lovorka ; Thompson, David D. ; Paralkar, Vishwas M. ; Čičin-Šain, Lipa ; Vukičević, Slobodan ; Mokrović, Gordana et al. | Elevated levels of serotonin decrease bone volume by direct effects on bone turnover in rats // Bone Abstracts. | Lisabon: bioscientifica, 2013. str. 100-x
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Erjavec, Igor ; Bordukalo Nikšić, Tatjana ; Brkljačić, Jelena ; Grčević, Danka ; Pauk, Martina ; Grgurević, Lovorka ; Mokrović, Gordana ; Kesić, Maja ; Đurđević, Dragan ; Rogić, Dunja et al. | Elevated blood serotonin decreases bone volume via a mechanism involving insulin and calcitriol // European Calcified Tissue Society Congress (ECTS 2014) : Abstracts Book ; u: Bone Abstracts 3 (2014). | Prag: BioScientifica, 2014. str. 68-68
www.bone-abstracts.orgwww.bone-abstracts.org Kesić, Maja ; Čicin-Šain, Lipa ; Desoye, Gernot ; Wadsack, Christian ; Panzenboeck, Ute ; Štefulj, Jasminka | Biochemical and pharmacological characterisation of the serotonin transporter (SERT) in primary trophoblasts of the human placentas // Book of Abstracts 4th Croatian Congres of Neuroscience /. | Zagreb: Hrvatsko društvo za neuroznanost ; Hrvatski institut za istraživanje mozga Medicinskog fakulteta Sveučilišta u Zagrebu, 2013. str. 39-39
Štefulj, Jasminka ; Kesić, Maja ; Čičin-Šain, Lipa | Differential expression of obesity-related genes in hypothalamus of Wistar-Zagreb 5HT rats // Book of Abstracts 4th Croatian Congres of Neuroscience /. | Zagreb: Hrvatsko društvo za neuroznanost ; Hrvatski institut za istraživanje mozga Medicinskog fakulteta Sveučilišta u Zagrebu, 2013. str. 49-49
Kesić, Maja ; Štefulj, Jasminka ; Mokrović, Gordana ; Čičin-Šain, Lipa | The effect of chronic fluoxetine on anxiety- like behavior and expression of 5HT-related proteins in rats with constitutionally altered 5HT homeostasis // BMC Pharmacology and Toxicology. | 2012
Kesić, Maja ; Bordukalo-Nikšić, Tatjana ; Mokrović, Gordana ; Čičin-Šain, Lipa | Effect of acute injection of fluoxetine in rats with constitutional upregulation/downregulation of platelet serotonin transporter // SiNAPSA Neuroscience Conference '11 - Book of Abstracts. | Ljubljana: Slovenian Neuroscience Association, 2011. str. 87-x
Publications - Conference journals
Sažetak izlaganja sa skupa
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Horvatiček, Marina ; Baković, Petra ; Ercegovac, Zvonimir ; Kesić, Maja ; Čičin-Šain, Lipa ; Starčević, Mirta ; Ivanišević, Marina ; Štefulj, Jasminka. | Serotonin uptake into human cord blood platelets: modulation by maternal metabolic state // FEBS Open Bio, 2021. str. 205-206
2021.febscongress.orgfebs.onlinelibrary.wiley.com -
Kesić, Maja ; Baković, Petra ; Kolarić, Darko ; Štefulj, Jasminka ; Čičin-Šain, Lipa | Adaptive thermogenesis in brown adipose tissue is affected by constitutive serotonergic tone: study on Wistar-Zagreb 5HT rat model // Obesity Facts, 2019. str. 96-96
www.karger.comwww.karger.com Kesić, Maja ; Tvrdeić, Ante ; Čičin-Šain, Lipa | Pain sensitivity and analgesis response in Wistar- Zagreb 5HT rats with constitutionally altered serotonin transporter // Periodicum biologorum, 2013. str. 71-71
Publications - Graded papers
Diplomski rad
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Surić, Lucija | Ekspresija gena za serotoninski receptor tip 2C u podlinijama štakora Wistar-Zagreb 5HT / Štefulj, Jasminka (mentor); Kesić, Maja (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2018
zir.nsk.hr Kesić, Maja | Cjelovitost DNA u stanicama lista i korijena boba kao pokazatelj genotoksičnosti talijeva(I) acetata / Pavlica, Mirjana (mentor); Cvjetko, Petra (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009
Doktorska disertacija
Kesić, Maja | Neurokemijski, molekularni i bihevioralni odgovor na farmakološku aktivaciju serotoninskoga sustava u štakora s promijenjenom homeostazom serotonina / Čičin-Šain, Lipa ; Štefulj, Jasminka (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2016
Membership in professional associations / societies
- Member of Croatian Society for Neuroscience (CSFN) - member of FENS
- Croatian Genetic Society
- Croatian Society of Biochemistry and Molecular Biology
- Croatian Laboratory Animal Science Association