2008 - PhD in Natural Sciences-Biology, Faculty of Science, University of Zagreb
2004 - MSc in Natural Sciences-Biology, Faculty of Science, University of Zagreb
1999 - BSc in Molecular Biology, Faculty of Science, University of Zagreb

Regulation of large-scale endocytosis by IQGAP-related proteins IqgC and IqgD (Croatian Science Foundation)

National award for science in 2019.

RBI award for best papers published in 2019.

Filić, V., Mijanović, L., Putar, D., Talajić, A., Ćetković, H., and Weber, I. (2021). Regulation of the Actin Cytoskeleton via Rho GTPase Signalling in Dictyostelium and Mammalian Cells: A Parallel Slalom. Cells 10, 1592.

Marinović, M., Mijanović, L., Šoštar, M., Vizovišek, M., Junemann, A., Fonović, M., Turk, B., Weber, I., Faix, J., and Filić, V. (2019). IQGAP-related protein IqgC suppresses Ras signaling during large-scale endocytosis. Proc. Natl. Acad. Sci. U.S.A 116, 1289–1298.

Filić, V., Marinović, M., Šoštar, M., and Weber, I. (2018). Modulation of small GTPase activity by NME proteins. Laboratory Investigation 98, 589–601.

Junemann, A., Filić, V., Winterhoff, M., Nordholz, B., Litschko, C., Schwellenbach, H., Stephan, T., Weber, I., and Faix, J. (2016). A Diaphanous-related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis. Proc. Natl. Acad. Sci. U.S.A. 113, E7464–E7473.

Sobočanec, S., Filić, V., Matovina, M., Majhen, D., Šafranko, Ž.M., Hadžija, M.P., Krsnik, Ž., Kurilj, A.G., Šarić, A., Abramić, M., et al. (2016). Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo. Redox Biol 8, 149–159.

Filić, V., Marinović, M., Faix, J., and Weber, I. (2014). The IQGAP-related protein DGAP1 mediates signaling to the actin cytoskeleton as an effector and a sequestrator of Rac1 GTPases. Cell. Mol. Life Sci. 71, 2775–2785.

Filić, V., Marinović, M., Faix, J., and Weber, I. (2012). A dual role for Rac1 GTPases in the regulation of cell motility. J. Cell. Sci. 125, 387–398.

Journal articles

Scientific and review papers

• Filić, V., Mijanović, L., Putar, D., Talajić, A., Ćetković, H. & Weber, I. (2021) Regulation of the Actin Cytoskeleton via Rho GTPase Signalling in Dictyostelium and Mammalian Cells: A Parallel Slalom. Cells, 10 (7), 1592, 39 doi:10.3390/cells10071592.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Bodinier, R., Sabra, A., Leiba, J., Marchetti, A., Lamrabet, O., Ayadi, I., Filić, V., Kawata, T., Weber, I. & Cosson, P. (2021) Role of LrrkA in the Control of Phagocytosis and Cell Motility in Dictyostelium discoideum. Frontiers in cell and developmental biology, 9, 629200, 11 doi:10.3389/fcell.2021.629200.

  doiwww.frontiersin.orgfulir.irb.hr

• Podgorski, I., Pinterić, M., Marčinko, D., Popović Hadžija, M., Filić, V., Ciganek, I., Pleše, D., Balog, T. & Sobočanec, S. (2020) Combination of sirtuin 3 and hyperoxia diminishes tumorigenic properties of MDA-MB-231 cells. Life sciences, 254, 117812, 13 doi:10.1016/j.lfs.2020.117812.

  doi

• Pinterić, M., Podgorski, I., Popović- Hadžija, M., Filić, V., Paradžik, M., Proust, B., Dekanić, A., Ciganek, I., Pleše, D., Marčinko, D., Balog, T. & Sobočanec, S. (2020) Sirt3 Exerts Its Tumor-Suppressive Role by Increasing p53 and Attenuating Response to Estrogen in MCF-7 Cells. Antioxidants, 9 (4), 294, 21 doi:10.3390/antiox9040294.

  doiwww.mdpi.comfulir.irb.hr

• Saidu, N., Filić, V., Thomas, M., Sarabia-Vega, V., Đukić, A., Miljković, F., Banks, L. & Tomaić, V. (2019) PDZ Domain-Containing Protein NHERF-2 Is a Novel Target of Human Papillomavirus 16 (HPV-16) and HPV-18. Journal of virology, 94 (1), e00663-19 doi:10.1128/JVI.00663-19.

  doi

• Buljubašić, M., Hlevnjak, A., Repar, J., Đermić, D., Filić, V., Weber, I., Zahradka, K. & Zahradka, D. (2019) RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli. DNA repair, 83, 102670, 16 doi:10.1016/j.dnarep.2019.102670.

  doi

• Marinović, M., Mijanović, L., Šoštar, M., Vizovišek, M., Junemann, A., Fonović, M., Turk, B., Weber, I., Faix, J. & Filić, V. (2019) IQGAP-related protein IqgC suppresses Ras signaling during large-scale endocytosis. Proceedings of the National Academy of Sciences of the United States of America, 116 (4), 1289-1298 doi:10.1073/pnas.1810268116.

  doi

• Filić, V., Marinović, M., Šoštar, M. & Weber, I. (2018) Modulation of small GTPase activity by NME proteins. Laboratory investigation, 98 (5), 589-601 doi:10.1038/s41374-018-0023-x.

  doi

• Junemann, A., Filić, V., Winterhoff, M., Nordholz, B., Litschko, C., Schwellenbach, H., Stephan, T., Weber, I. & Faix, J. (2016) A Diaphanous-related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis. Proceedings of the National Academy of Sciences of the United States of America, 113 (47), E7464-E7473 doi:10.1073/pnas.1611024113.

  doi

• Marinović, M., Šoštar, M., Filić, V., Antolović, V. & Weber, I. (2016) Quantitative imaging of Rac1 activity in Dictyostelium cells with a fluorescently labelled GTPase-binding domain from DPAKa kinase. Histochemistry and cell biology, 146 (3), 267-279 doi:10.1007/s00418-016-1440-9.

  doi

• Sobočanec, S., Filić, V., Matovina, M., Majhen, D., Šafranko, Ž., Popović Hadžija, M., Krsnik, Ž., Gudan Kurilj, A., Šarić, A., Abramić, M. & Balog, T. (2016) Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo. Redox Biology, 8, 149-159 doi:10.1016/j.redox.2016.01.003.

  doi

• Filić, V., Marinović, M., Faix, J. & Weber, I. (2014) The IQGAP-related protein DGAP1 mediates signaling to the actin cytoskeleton as an effector and a sequestrator of Rac1 GTPases. Cellular and molecular life sciences, 71 (15), 2775-2785 doi:10.1007/s00018-014-1606-3.

  doi

• Antolović, V., Marinović, M., Filić, V. & Weber, I. (2014) A simple optical configuration for cell tracking by dark-field microscopy. Journal of microbiological methods, 104, 9-11 doi:10.1016/j.mimet.2014.06.006.

  doi

• Bursać, S., Cokarić Brdovčak, M., Pfannkuchen, M., Oršolić, I., Golomb, L., Zhu, Y., Katz, C., Daftuar, L., Grabušić, K., Vukelić, I., Filić, V., Oren, M., Prives, C. & Volarević, S. (2012) Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress. Proceedings of the National Academy of Sciences of the United States of America, 109 (50), 20467-20472 doi:10.1073/pnas.1218535109.

  doi

• Filić, V., Marinović, M., Faix, J. & Weber, I. (2012) A dual role for Rac1 GTPases in the regulation of cell motility. Journal of cell science, 125 (2), 387-398 doi:10.1242/jcs.089680.

  doi

• Annesley, S., Bago, R., Herak Bosnar, M., Filić, V., Marinović, M., Weber, I., Mehta, A. & Fisher, P. (2011) Dictyostelim discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis. PLoS One, 6 (10), e26024, 11 doi:10.1371/journal.pone.0026024.

  doiwww.plosone.orgfulir.irb.hr

• Jeličić, B., Traven, A., Filić, V. & Sopta, M. (2005) Mitochondrial dysfunction enhances Gal4 dependent transcription. FEMS microbiology letters, 253 (2), 207-213 doi:10.1016/j.femsle.2005.09.033.

  doi

• Filić, V., Vladić, A., Štefulj, J., Čičin-Šain, L., Balija, M., Sučić, Z. & Jernej, B. (2005) Monoamine Oxidases A and B Gene Polymorphisms in Migraine Patients. Journal of the neurological sciences, 228 (2), 149-153 doi:10.1016/j.jns.2004.11.045.

  doi

Croatian Society of Biochemistry and Molecular Biology, member of Executive Committee

Croatian Microscopy Society