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Laboratory for chemical and biological crystallography

Laboratory for chemical and biological crystallography
<span class="Y2IQFc">The research in the Laboratory for chemical and biological crystallography (LCBC) is focused on using X-ray diffraction for determining crystal structures of smal organic molecules, organo-metalic complexes, biological macromolecules such as proteins (enzymes) and DNA molecules. In addition we are interested in protein-ligand interactions using X-ray diffraction methods, molecular modeling, and spectroscopic methods. 
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  • adoption of new experimental and computational methods in X-ray diffraction by the single crystal method;
  • adoption and adaptation of graphic software for visualization of molecule structure and work with databases;
  • research in the field of molecular enzymology: biochemical, structural, genetic and kinetic research of new bacterial lipases with the aim of understanding biocatalysis;
  • molecular modeling of proteins and their specifics - lipases, intra- and extracellular proteins, auxin receptors;
  • the role and topology of hydrogen bonds in (bio) nano-materials;
  • structural characterization of new compounds and determining the relationship between structure and activity.

Division of Physical Chemistry

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