<span class="Y2IQFc">The research in the Laboratory for chemical and biological crystallography (LCBC) is focused on using X-ray diffraction for determining crystal structures of smal organic molecules, organo-metalic complexes, biological macromolecules such as proteins (enzymes) and DNA molecules. In addition we are interested in protein-ligand interactions using X-ray diffraction methods, molecular modeling, and spectroscopic methods.
- adoption of new experimental and computational methods in X-ray diffraction by the single crystal method;
- adoption and adaptation of graphic software for visualization of molecule structure and work with databases;
- research in the field of molecular enzymology: biochemical, structural, genetic and kinetic research of new bacterial lipases with the aim of understanding biocatalysis;
- molecular modeling of proteins and their specifics - lipases, intra- and extracellular proteins, auxin receptors;
- the role and topology of hydrogen bonds in (bio) nano-materials;
- structural characterization of new compounds and determining the relationship between structure and activity.