Associate, CSF project:

Integrin αVβ5-associated Focal and Reticular Adhesions in Melanoma (AdMeFoRe ) - Ruđer Bošković Institute (irb.hr)

• Integrin alpha V beta 5-associated Focal and Reticular Adhesions in Melanoma - AdMeFoRe

  01.02.2020 - 31.01.2024 | 132,722.81 EUR

  CroRISIRB

Rac, A., Lončarić, M., Stojanović, N., Fatima, M., Rešetak, M., Hršak, D., Humphries, JD., Humphries, M., Ambriović-Ristov, A. Regulation of reticular adhesions by KANK2 and talin2 in two melanoma cell lines. Cell Commun Signal (2026). https://doi.org/10.1186/s12964-026-02904-1

Stojanović, N., Rac, A., Lončarić, M., Tadijan, A., Paradžik, M., Acman, M., Humphries, JD., Humphries, M., Ambriović-Ristov, A. KANK2 at focal adhesions regulates their maintenance and dynamics, while at fibrillar adhesions it influences cell migration via microtubule-dependent mechanism. Cell Commun Signal 24, 224 (2026). https://doi.org/10.1186/s12964-026-02771-w

Lončarić, M.; Stojanović, N.; Rac-Justament, A.; Coopmans, K.; Majhen, D.; Humphries, J.; Humphries, M.; Ambriović Ristov, A. (2023) Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line. Cellular & molecular biology letters, 28, 56, https://doi.org/10.1186/s11658-023-00473-6

Paradžik, M; Humphries, J D. ; Stojanović, N ; Nestić, D ; Majhen, D ; Dekanić, A ; Samaržija, I ; Sedda, D ; Weber, I ; Humphries, M J.; Ambriović-Ristov, A  KANK2 links αVβ5 focal adhesions to microtubules and regulates sensitivity to microtubule poisons and cell migration  Frontiers in cell and developmental biology, 8 (2020), 125, 17. doi: 10.3389/fcell.2020.00125

Stojanović, N; Dekanić, A; Paradžik, M; Majhen, D; Ferenčak, K; Ruščic, J; Bardak, I; Supina, C; Tomičić, M T. ; Christmann, M; Osmak, M; Ambriović-Ristov, A  Differential effects of integrin αv knockdown and cilengitide on sensitisation of triple-negative breast cancer and melanoma cells to microtubule poisons  Molecular pharmacology, 94 (2018), 6; 1334-1351. doi: 10.1124/mol.118.113027

Stojanović, N; Brozovic, A; Majhen, D; Herak Bosnar, M; Fritz, G; Osmak, M; Ambriović-Ristov, A  Integrin αvβ3 Expression in Tongue Squamous Carcinoma Cells Cal27 Confers Anticancer Drug Resistance Through Loss of pSrc(Y418)  Biochimica et biophysica acta. Molecular cell research, 1863 (2016), 8; 1969-1978. doi: 10.1016/j.bbamcr.2016.04.019