Exciting news! Our latest data reveal new mechanism of DNA-protein crosslink repair in vivo, shedding new light on understanding DPC-related diseases and identifying potential chemotherapeutic targets. Check our pre-print 'Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA-protein crosslinks in vivo’ at: https://www.biorxiv.org/content/10.1101/2023.03.01.530659v1.
Exciting news! Our latest data reveal new mechanism of DNA-protein crosslink repair in vivo, shedding new light on understanding DPC-related diseases and identifying potential chemotherapeutic targets. Check our pre-print 'Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA-protein crosslinks in vivo’ at: https://www.biorxiv.org/content/10.1101/2023.03.01.530659v1.