Abstract: Within this project we propose the use of a catalytic system containing a coordination cage host and a chiral guest. The working hypothesis is that the transmission of chirality from the chiral guest to the achiral cage host can induce enantioselectivity of a catalytic reaction outside of the cage. The host-guest chemistry of these coordination cages will be studied by experimental and computational methods in order to identify the most suitable guests for particular cages.
PI: Srećko Kirin; assistants: Marija Bakija, Filip Grdović (since 10.2024.), Alen Martinko (since 01.2026.), Dario Šušnić (since 12.2024.); associates: Nikola Biliškov (until 12.2025.), Ines Despotović, Zoran Kokan, Berislav Perić, Tomislav Portada, Đani Škalamera; collaborators from abroad: Eszter Barath, Kevin Cariou, Gilles Gasser, Saša Opačak (since 02.2025.), Sergey Tin
Scientific papers.
3. M. Bakija, B. Perić, T. Rinkovec, E. Sanders, Z. Kokan, Z. Štefanić, R. Vianello, S. I. Kirin*: "Induction of helical chirality in tetrahedral transition metal complexes with non-bridging monodentate oxazolines", Dalton Trans. 2025, 54, 17083-17101; [Q1, IF2024 = 3.3]. Doi: 10.1039/d5dt02399h
2. M. Bakija, S. Opačak, B. Perić, S. Chakrabortty, A. Dell’Acqua, E. Barath, J. G. de Vries, S. Tin,* S. I. Kirin*: "Supramolecular bidentate rhodium(I) or iridium(I) phosphine and oxazoline amino acid bioconjugates as selective catalysts for enantioselective reactions", Dalton Trans. 2025, 54, 1021-1037; [Q1, IF2024 = 3.3]. Doi: 10.1039/d4dt02519a
1. M. Bakija, B. Perić, S. I. Kirin*: "Oxazoline amino acid bioconjugates: One-pot synthesis and analysis of supramolecular interactions", New J. Chem. 2024, 48, 8702-8719; [Q3, IF2024 = 2.5]. Doi: 10.1039/d4nj00995a
Conference contributions.
15. M. Bakija: The story about turn catalysts: supramolecular bidentate metal complexes, Workshop on supramolecular chemistry, Zagreb, 26.-27.09.2025.; oral presentation.
14. D. Šušnić, B. Perić, Z. Kokan: Benzene-1,3,5-tricarboxamide systems: host-guest interactions, photoswitching, and ion coordination, 29th Croatian Meeting of Chemists and Chemical Engineers and 7th Symposium Vladimir Prelog, Book of abstracts, Split, 02.-05.09.2025., str. 190; poster.
13. F. Grdović, Z. Kokan, S. Kirin: Enantioselective Transition Metal Catalysis with Self-assembled Host-Guest Systems, 29th Croatian Meeting of Chemists and Chemical Engineers and 7th Symposium Vladimir Prelog, Book of abstracts, Split, 02.-05.09.2025., str. 123; poster.
12. D. Šušnić, B. Perić, Z. Kokan: Acyl-hydrazone benzene-1,3,5-tricarboxamides: supramolecular interactions and coordination properties, Solid-State Science & Research Meeting, Zagreb, 02.-04.07.2025., Book of Abstracts and Programme, P45, str. 109; poster.
11. R. Ilijov, M. Bakija, B. Perić, S. I. Kirin: "Synthesis and characterization of bivalent metal complexes of monodentate oxazoline ligands", Solid-State Science & Research Meeting, Zagreb, 02.-04.07.2025. Book of Abstracts and Programme, P11, p. 75; poster.
10. M. Bakija, R. Ilijov, B. Perić, S. I. Kirin: "Late transition metal complexes containing amino acid bioconjugates of monodentate oxazolines", 17th International Symposium on Applied Bioinorganic Chemistry, Uppsala, Švedska, 15.-18.06.2025., P6-084, str. 219; poster.
9. F. Grdović, Z. Kokan, N. Biliškov, I. Despotović, B. Perić, S. I. Kirin: "Towards chiral coordination cages: Ligand, guest design and complexation studies with transition metals", 2nd Global Action Meeting (CA 22131), Zadar, 28.-29.04.2025., Book of Abstracts, P14, str. 48; poster.
8. M. Bakija, T. Rinkovec, B. Perić, E. Sanders, Z. Štefanić, R. Vianello, S. I. Kirin: "Helical chirality in tetrahedral transition metal complexes of 2-aryl-(4S)-phenyl oxazolines", 2nd Global Action Meeting (CA 22131), Zadar, 28.-29.04.2025., Book of Abstracts, C20, str. 27; oral presentation.
7. S. Opačak, M. Bakija, B. Perić, S. Chakrabortty, A. Dell’Acqua, E. Barath, J. G. de Vries, S. Tin, S. I. Kirin: "Backdoor induction of chirality and its application to hydrogenation and hydroformylation reactions utilising naturally available amino acid building blocks", Symposium on Renewable Resources and C1 Catalysis, Shanghai Jiao Tong University, Kina, 05.12.2024.; oral presentation.
6. B. Perić, M. Bakija, S. I. Kirin: "DFT Calculation and nmr spectroscopy of an oxazoline amino acid bioconjugate: supramolecular dimers vs. monomers", Central European NMR Symposium & Bruker Users’ Meeting, Rijeka, 18.-19.09.2024., Book of Abstracts, p. 45; poster.
5. M. Bakija, B. Perić, R. Vianello, S. I. Kirin: "Group 11 metal complexes of chiral monodentate oxazoline ligands", 8th EuChems Conference on Nitrogen Ligands, Cassis, Francuska, 03.06.-07.06.2024., Book of Abstracts, p. 96; poster.
4. M. Bakija, B. Perić, R. Vianello, S. I. Kirin: "Synthesis and characterization of transition metal complexes with chiral monodenate oxazoline ligands", 14th Inorganic & Bioinorganic Chemistry Conference, Lisabon, Portugal, 16.-18.05.2024., Abstract Book, p. 29; oral presentation.
3. S. I. Kirin: "Metallated Amino Acid Bioconjugates: Supramolecular Chemistry and Catalysis", Global Action Meeting (CA 22131), Abano Terme (Padova), Italija, 18.-19.04.2024., Abstract Book, str. 46.; poster.
2. M. Bakija, S. Opačak, S. Chakrabortty, A. Dell’Acqua, E. Barath, J. de Vries, S. Tin, S. I. Kirin: "Amino acid bioconjugate P- and N-ligands and iridium or rhodium catalyzed asymmetric hydrogenation" 26.-27.04.2024., 8. Simpozij studenata doktorskih studija PMF-a, Zagreb, Book of Abstracts, str. 28; oral presentation.
1. M. Bakija, B. Perić, S. I. Kirin: "One-pot synthesis and supramolecular interaction analysis of oxazoline amino acid bioconjugates", 15. Susret mladih kemijskih inženjera, Zagreb, 22.-23.02.2024., Book of Abstracts, str. 93; poster.
