Dr. Dubravka Švob Štrac
Division of Molecular Medicine
Laboratory for Molecular Neuropsychiatry
Bijenicka 54
10000 Zagreb, Croatia
Education
1998. - B. Sc. degree in Molecular Biology, Faculty of Science, University of Zagreb, Croatia
2004. - M.Sc. degree in Molecular and Cell Biology, Faculty of Science, University of Zagreb, Croatia
2007. - Ph.D. degree in Molecular and Cell Biology, Faculty of Science, University of Zagreb, Croatia
2011. - Specialist of Project Management, Accredited College of Business and Management, Zapresic, Croatia
Projects
2009. –present - project financed by Croatian Ministry od Science, Education and Sports - “Stress, GABA-A and mechanisms of neuropsychoactive drugs”
Classes
associate in “Neuroimmunology” classes at Faculty of Science, University of Zagreb, Croatia
Featured Publications
- Pericic D, Svob D, Jazvincak M, Mirkovic K: Anticonvulsive effect of swim stress in mice. Pharmacol. Biochem. Behav. 66 (4): 879-886 (2001)
- Pericic D, Svob D: Interaction of stress and noradrenergic drugs in the control of picrotoxin-induced seizures. Epilepsy Res. 51 (1-2): 179-187 (2002)
- Pericic D, Svob Strac D, Jazvinscak Jembrek M, Rajcan I: Prolonged exposure to gamma-aminobutyric acid up-regulates stably expressed recombinant alpha1beta2gamma2s GABAA receptors: Eur. J. Pharmacol. 482: 117-125 (2003)
- Pericic D, Svob Strac D, Vlainic J: Zimelidine decreases seizure susceptibility in stressed mice. J. Neural Transm. 113 (12): 1863-1871 (2006)
- Pericic D, Svob Strac D: The role of 5-HT7 receptors in the control of seizures. Brain Res. 1141: 48-55 (2007)
- Pericic D, Svob Strac D, Jazvinscak Jembrek M, Vlainic J: Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with α1β2γ2S subunits of GABAA receptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 375 (3): 177-187 (2007)
- Pericic D, Svob Strac D, Vlainic J: Interaction of diazepam and swim stress. Brain Res. 1184C: 81-87 (2007)
- Jazvinscak Jembrek M, Svob Strac D, Vlainic J, Pericic D: The role of transcriptional and translational mechanisms in flumazenil-induced up-regulation of recombinant GABAA receptors. Neurosci. Res. 61 (3): 234-241 (2008)
- Svob Strac D, Vlainic J, Jazvinscak Jembrek M, Pericic D: Differentail effects of diazepam treatment and withdrawal on recombinant GABAA receptor expression and functional coupling. Brain Res. 1246: 29-40 (2008)
Publications
Books and book chapters
Book chapters
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Tudor, L., Konjevod, M., Nikolac Perković, M., Švob Štrac, D., Nedić Erjavec, G., Uzun, S., Kozumplik, O., Šagud, M., Kovačić Petrović, Z. & Pivac, N. (2020) Genetic variants of the brain-derived neurotrophic factor and metabolic indices inveterans with posttraumatic stress disorder. U: Frye, R., Rose, S., Martorell, L. & Boles, R. (ur.) Metabolic ad Immune Disorders Associated with Psychiatric Disease: Potential Etiology and Pathway for Treatment. Lausanne, Frontiers Media SA, str. 5-17 doi:10.3389/fpsyt.2018.00637.
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Šagud, M., Tudor, L., Uzun, S., Nikolac Perković, M., Živković, M., Konjevod, M., Kozumplik, O., Vuksan Ćusa, B., Švob Štrac, D., Radoš, I., Mimica, N., Mihaljević Peleš, A., Nedić Erjavec, G. & Pivac, N. (2020) Haplotypic and genotypic association of catechol-o-methyltransferase rs4680 and rs4818 polymorphisms and treatment resistance in schizophrenia. U: Manchia, M. & Carpiniello, B. (ur.) Decreasing the impact of treatment resistance in schizophrenia: Identifying novel molecular targets/pathways to increase treatment efficacy. Lausanne, Frontiers Media SA, str. 8-21 doi:10.3389/fphar.2018.00705.
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Nedić Erjavec, G., Nikolac Perković, M., Tudor, L., Švob Štrac, D. & Pivac, N. (2020) Neurotransmitter and neurotrophic biomarkers in combat related PTSD. U: Updesh, K. (ur.) The Routledge International Handbook of Military Psychology and Mental Health. London, Routledge Taylor & Francis Group, str. 467-481 doi:10.4324/9780429281266-31.
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Nedić Erjavec, G., Švob Štrac, D., Tudor, L., Konjevod, M., Šagud, M. & Pivac, N. (2019) Genetic Markers in Psychiatry. U: Kim, Y. (ur.) Frontiers in Psychiatry: Artificial Intelligence, Precision Medicine, and Other Paradigm Shifts. Singapore, Springer, str. 53-93 doi:10.1007/978-981-32-9721-0_4.
doi Nedić Erjavec, G., Nikolac Perković, M., Švob Štrac, D. & Pivac, N. (2017) Biomarkers of treatment response in depression. U: Yong-Ku, K. (ur.) Major Depressive Disorder: Risk Factors, Characteristics and Treatment Options. New York, NOVA SCI Publishers, str. 181-233.
Svob Strac, D., Samardzic, J., Erhardt, J., Krsnik, Z., Martinovic, J., Drakulic, D., Tudor, L., Nikolac Perkovic, M., Nedic Erjavec, G. & Pivac, N. (2017) In Vitro and In Vivo Studies of Prolonged DHEA(S) Treatment. U: Berhardt, L. (ur.) Advances in Medicine and Biology. Volume 117. New York, NOVA Science Publishers, str. 69-98.
Pivac, N., Nikolac Perković, M. & Švob Štrac, D. (2017) The genetics of obesity. U: Štimac, D. (ur.) Debljina-klinički pristup. Zagreb, Medicinska naklada, str. 69-81.
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Samardžić, J., Švob Štrac, D. & van den Anker, J. (2017) The Benefit and Future of Pharmacogenetics. U: Absalom, A. & Mason, K. (ur.) Total Intravenous Anesthesia and Target Controlled Infusions. A Comprehensive Global Anthology. Switzerland, Springer International Publishing, str. 697-711 doi:10.1007/978-3-319-47609-4_38.
doi Samardžić, J. & Švob Štrac, D. (2016) Benzodiazepines and Anxiety Disorders: From Laboratory to Clinic. U: Durbano, F. & Marchesi, B. (ur.) New Developments in Anxiety Disorders., InTech, str. 23-45.
Pivac, N., Svob Strac, D., Nikolac Perkovic, M. & Nedic Erjavec, G. (2015) How laboratory can help us in the selection of antipsychotics. U: Mihaljević Peleš, A. & Šagud, M. (ur.) Klinička primjena antipsihotika. Zagreb, Medicinska naklada, str. 21-38.
Švob Štrac, D., Nikolac Perković, M., Nedić Erjavec, G., Kiive, E., Dodig-Ćurković, K., Ćurkovic, M., Kocijan Hercigonja, D., Harro, J., Muck-Šeler, D. & Pivac, N. (2014) Biomarkers of Impulsivity. U: Olmstead, C. (ur.) Psychology of Impulsivity: New Research. New York, Nova Science Publishers, Inc., str. 93-140.
Švob Štrac, D., Muck Šeler, D. & Pivac, N. (2014) The effects of GABA and GABAergic drugs on the HPA axis activity. U: Vlainić, J. & Jazvinšćak Jembrek, M. (ur.) Gamma-aminobutyric Acid (GABA): biosynthesis, medicinal uses and health effects. New York, Nova Science Publishers, str. 71-92.
Vlainić, J., Švob Štrac, D. & Jazvinšćak Jembrek, M. (2014) The effects of persistent activation of GABA-A receptors by neurotransmitter GABA. U: Vlainić, J. & Jazvinšćak Jembrek, M. (ur.) Gamma-aminobutyric Acid (GABA): biosynthesis, medicinal uses and health effects. New York, Nova Science Publishers, str. 29-48.
Švob Štrac, D., Mustapić, M., Šagud, M., Uzun, S., Kozumplik, O., Presečki, P., Nikolac, M., Mimica, N., Nedić, G., Mihaljević Peleš, A., Pavlović, M., Marčinko, D., Pivac, N. & Mück-Šeler, D. (2013) Lipid levels in neuropsychiatric disorders. U: Araujo, C. & Perez, D. (ur.) Tryglicerides : chemical structure, biosynthesis and role in disease. New York, NOVA Science Publisher, Inc., str. 1-79.
Švob Štrac, D., Vlainić, J., Jazvinšćak Jembrek, M., Muck-Šeler, D. & Pivac, N. (2012) The Effects of Benzodiazepines during Prolonged Administration and Under the Conditions of Stress. U: Soto, A. & Reyes, C. (ur.) Benzodiazepine: Abuse and Therapeutic Uses, Pharmacology and Health Effects. New York, USA, Nova Science Publishers, Inc., str. 1-54.
Pivac, N., Nedić, G., Nikolac, M., Mustapić, M., Švob Štrac, D., Jazvinšćak Jembrek, M. & Muck-Šeler, D. (2011) Molecular mechanisms of traumatic brain injury. U: Wiederhold, B. (ur.) Traumatic brain injury. Wounds of war III.. Amsterdam, IOS Press, str. 81-111.
Journal articles
Scientific and review papers
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Nikolac Perkovic, M., Borovecki, F., Filipcic, I., Vuic, B., Milos, T., Nedic Erjavec, G., Konjevod, M., Tudor, L., Mimica, N., Uzun, S., Kozumplik, O., Svob Strac, D. & Pivac, N. (2023) Relationship between Brain-Derived Neurotrophic Factor and Cognitive Decline in Patients with Mild Cognitive Impairment and Dementia. Biomolecules, 13 (3), 570, 14 doi:10.3390/biom13030570.
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Vuić, B., Miloš, T., Tudor, L., Konjevod, M., Nikolac Perković, M., Jazvinšćak Jembrek, M., Nedić Erjavec, G. & Švob Štrac, D. (2022) Cannabinoid CB2 Receptors in Neurodegenerative Proteinopathies: New Insights and Therapeutic Potential. Biomedicines, 10 (12), 3000, 31 doi:10.3390/biomedicines10123000.
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Nedić Erjavec, G., Grubor, M., Živković, M., Božina, N., Šagud, M., Nikolac Perković, M., Mihaljević-Peleš, A., Pivac, N. & Švob Štrac, D. (2022) SLC6A3, HTR2C and HTR6 Gene Polymorphisms and the Risk of Haloperidol-Induced Parkinsonism. Biomedicines, 10 (12), 3237, 16 doi:10.3390/biomedicines10123237.
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Babić Leko, M., Nikolac Perković, M., Španić, E., Švob Štrac, D., Pleić, N., Vogrinc, Ž., Gunjača, I., Bežovan, D., Nedić Erjavec, G., Klepac, N., Borovečki, F., Zemunik, T., Pivac, N., Hof, P. & Šimić, G. (2022) Serotonin receptor gene polymorphisms are associated with cerebrospinal fluid, genetic, and neuropsychological biomarkers of Alzheimer’s disease. Biomedicines, 10 (12), 3118, 13.
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Konjevod, M., Sáiz, J., Nikolac Perković, M., Nedić Erjavec, G., Tudor, L., Uzun, S., Kozumplik, O., Barbas, C., Žarkovic, N., Pivac, N. & Švob Štrac, D. (2022) Plasma lipidomics in subjects with combat posttraumatic stress disorder. Free radical biology & medicine, 189, 169-177 doi:10.1016/j.freeradbiomed.2022.07.012.
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Domitrović Spudić, S., Nikolac Perković, M., Uzun, S., Nedić Erjavec, G., Kozumplik, O., Švob Štrac, D., Mimica, N. & Pivac, N. (2022) Reduced plasma BDNF concentration and cognitive decline in veterans with PTSD. Psychiatry research, 316, 114772, 10 doi:10.1016/j.psychres.2022.114772.
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Vuić, B., Konjevod, M., Tudor, L., Milos, T., Nikolac Perković, M., Nedić Erjavec, G., Pivac, N., Uzun, S., Mimica, N. & Švob Štrac, D. (2022) Tailoring the therapeutic interventions for behavioral and psychological symptoms of dementia. Expert Review of Neurotherapeutics, 22 (8), 707-720 doi:10.1080/14737175.2022.2112668.
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Tudor, L., Konjevod, M., Nedić Erjavec, G., Nikolac Perković, M., Uzun, S., Kozumplik, O., Zoldos, V., Lauc, G., Švob Štrac, D. & Pivac, N. (2022) Genetic and Epigenetic Association of Hepatocyte Nuclear Factor-1α with Glycosylation in Post-Traumatic Stress Disorder. Genes, 13 (6), 1063, 20 doi:10.3390/genes13061063.
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Repovečki, S., Nedić Erjavec, G., Uzun, S., Tudor, L., Nikolac Perković, M., Konjevod, M., Kozumplik, O., Švob Štrac, D., Kovačić Petrović, Z., Mimica, N. & Pivac, N. (2022) Reduced Platelet MAO-B Activity Is Associated with Psychotic, Positive, and Depressive Symptoms in PTSD. Biomolecules, 12 (5), 736, 18 doi:10.3390/biom12050736.
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Nedic Erjavec, G., Tudor, L., Nikolac Perkovic, M., Podobnik, J., Dodig Curkovic, K., Curkovic, M., Svob Strac, D., Cusek, M., Bortolato, M. & Pivac, N. (2022) Serotonin 5-HT 2A receptor polymorphisms are associated with irritability and aggression in conduct disorder. Progress in neuro-psychopharmacology & biological psychiatry, 117, 110542, 5 doi:10.1016/j.pnpbp.2022.110542.
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Pivac, N., Nedić Erjavec, G., Šagud, M., Nikolac Perković, M., Tudor, L., Uzun, S., Kovačić Petrović, Z., Konjevod, M., Dvojković, A., Kozumplik, O., Svob Strac, D., Peraica, T., Mimica, N., Živković, M., Hirasawa-Fujita, M. & Domino, E. (2022) The association between BDNF C270T genetic variants and smoking in patients with mental disorders and in healthy controls. Progress in neuro-psychopharmacology & biological psychiatry, 113, 110452, 10 doi:10.1016/j.pnpbp.2021.110452.
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Babić Leko, M., Nikolac Perković, M., Nedić Erjavec, G., Klepac, N., Švob Štrac, D., Borovečki, F., Pivac, N., Hof, P. & Šimić, G. (2021) Association of the MAOB rs1799836 single nucleotide polymorphism and APOE ɛ4 allele in Alzheimer's disease. Current Alzheimer research, 18 (7), 585-594 doi:10.2174/1567205018666210917162843.
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Nedić Erjavec, G., Bektić Hodžic, J., Repovecki, S., Nikolac Perković, M., Uzun, S., Kozumplik, O., Tudor, L., Mimica, N., Švob Štrac, D. & Pivac, N. (2021) Alcohol-related phenotypes and platelet serotonin concentration. Alcohol (Fayetteville, N.Y.), 97, 41-49 doi:10.1016/j.alcohol.2021.09.001.
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Švob Štrac, D., Konjevod, M., Sagud, M., Nikolac Perković, M., Nedić Erjavec, G., Vuić, B., Šimić, G., Vukić, V., Mimica, N. & Pivac, N. (2021) Personalizing the Care and Treatment of Alzheimer’s Disease: An Overview. Pharmacogenomics and Personalized Medicine, 14, 631-653 doi:10.2147/pgpm.s284615.
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Nedić Erjavec, G., Nikolac Perković, M., Tudor, L., Uzun, S., Kovačić Petrović, Z., Konjevod, M., Šagud, M., Kozumplik, O., Švob Štrac, D., Peraica, T., Mimica, N., Havelka Meštrović, A., Žilić, D. & Pivac, N. (2021) Moderating effects of BDNF genetic variants and smoking on cognition in PTSD veterans. Biomolecules, 11 (5), 641, 20 doi:10.3390/biom11050641.
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Nikolac Perković, M., Videtić Paska, A., Konjevod, M., Kouter, K., Švob Štrac, D., Nedić Erjavec, G. & Pivac, N. (2021) Epigenetics of Alzheimer’s Disease. Biomolecules, 11 (2), 195, 38 doi:10.3390/biom11020195.
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Nedić Erjavec, G., Šagud, M., Nikolac Perković, M., Švob Štrac, D., Konjevod, M., Tudor, L., Uzun, S. & Pivac, N. (2021) Depression: Biological markers and treatment. Progress in neuro-psychopharmacology & biological psychiatry, 105, 110139, 21 doi:10.1016/j.pnpbp.2020.110139.
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Konjevod, M., Nikolac Perković, M., Sáiz, J., Švob Štrac, D., Barbas, C. & Rojo, D. (2021) Metabolomics analysis of microbiota-gut-brain axis in neurodegenerative and psychiatric diseases. Journal of pharmaceutical and biomedical analysis, 194, 113681, 20 doi:10.1016/j.jpba.2020.113681.
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Dvojković, A., Nikolac Perković, M., Šagud, M., Nedić Erjavec, G., Mihaljević Peleš, A., Švob Štrac, D., Vuksan Ćusa, B., Tudor, L., Kušević, Z., Konjevod, M., Živković, M., Jevtović, S. & Pivac, N. (2021) Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry, 105, 110016, 30 doi:10.1016/j.pnpbp.2020.110016.
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Podobnik, J., Nikolac Perković, M., Nedić Erjavec, G., Dodig Ćurković, K., Ćurkovic, M., Kovač, V., Švob Štrac, D., Čusek, M., Bortolato, M. & Pivac, N. (2020) Detention in Juvenile Correctional Facilities Is Associated with Higher Platelet Monoamine Oxidase B Activity in Males. Biomolecules, 10 (11), 1555, 13 doi:10.3390/biom10111555.
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Havelka Meštrović, A., Tudor, L., Nedić Erjavec, G., Nikolac Perković, M., Švob Štrac, D., Kovačić Petrović, Z. & Pivac, N. (2020) The impact of BDNF Val66Met on cognitive skills in veterans with posttraumatic stress disorder. Neuroscience letters, 735, 135235, 4 doi:10.1016/j.neulet.2020.135235.
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Konjevod, M., Nedić Erjavec, G., Nikolac Perković, M., Sáiz, J., Tudor, L., Uzun, S., Kozumplik, O., Švob Štrac, D., Žarković, N. & Pivac, N. (2020) Metabolomics in posttraumatic stress disorder: Untargeted metabolomic analysis of plasma samples from Croatian war veterans. Free radical biology & medicine, 162, 636-641 doi:10.1016/j.freeradbiomed.2020.11.024.
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Sreter, K., Popović-Grle, S., Lampalo, M., Konjevod, M., Tudor, L., Nikolac Perković, M., Jukić, I., Bingulac-Popović, J., Safić Stanić, H., Markeljević, J., Pivac, N. & Švob Štrac, D. (2020) Plasma Brain-Derived Neurotrophic Factor (BDNF) concentration and BDNF/TrkB gene polymorphisms in Croatian adults with asthma. Journal of personalized medicine, 10 (4), 189, 20 doi:10.3390/jpm10040189.
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Culjak, M., Nikolac Perković, M., Uzun, S., Švob Štrac, D., Nedić Erjavec, G., Babić Leko, M., Šimić, G., Tudor, L., Konjevod, M., Kozumplik, O., Mimica, N. & Pivac, N. (2020) The association between TNF-alpha, IL-1 alpha and IL-10 with Alzheimer's disease. Current Alzheimer research, 17 (11), 972-984 doi:10.2174/1567205017666201130092427.
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Babić Leko, M., Nikolac Perković, M., Klepac, N., Švob Štrac, D., Borovečki, F., Pivac, N., Hof, P. & Šimić, G. (2020) IL-1beta, IL-6, IL-10, and TNFalpha single nucleotide polymorphisms in human influence the susceptibility to Alzheimer’s disease pathology. Journal of alzheimers disease, 75 (3), 1029-1047 doi:10.3233/JAD-200056.
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Konjevod, M., Nikolac, M., Svob Strac, D., Uzun, S., Nedic Erjavec, G., Kozumplik, O., Tudor, L., Mimica, N., Hirasawa-Fujita, M., Domino, F. & Pivac, N. (2020) Significant association of mu-opioid receptor 1 haplotype with tobacco smoking in healthy control subjects but not in patients with schizophrenia and alcohol dependence. Psychiatry research, 291, 113278, 7 doi:10.1016/j.psychres.2020.113278.
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Nikolac Perković, M., Šagud, M., Živković, M., Uzun, S., Nedić Erjavec, G., Kozumplik, O., Švob Štrac, D., Mimica, N., Mihaljević Peleš, A. & Pivac, N. (2020) Catechol-O-methyltransferase rs4680 and rs4818 haplotype association with treatment response to olanzapine in patients with schizophrenia. Scientific reports, 10 (1), 10049, 11 doi:10.1038/s41598-020-67351-5.
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Jakšić, N., Tudor, L., Nedić Erjavec, G., Nikolac Perković, M., Konjevod, M., Švob Štrac, D., Pivac, N., Uzun, S., Kozumplik, O. & Repovecki, S. (2020) Childhood trauma types and symptom severity in Croatian war veterans suffering from posttraumatic stress disorder (PTSD).. Psychiatry research, 284, 112762, 5 doi:10.1016/j.psychres.2020.112762.
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Švob Štrac, D., Konjevod, Marcela, Nikolac Perković, Matea, Tudor, L., Nedić Erjavec Gordana & Pivac, N. (2020) Dehydroepiandrosterone (DHEA) and its Sulphate (DHEAS) in Alzheimer's Disease.. Current alzheimer research, 7, 141-157 doi:10.2174/1567205017666200317092310.
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Grubor, M., Živković, M., Šagud, M., Nikolac Perković, M., Mihaljević-Peleš, A., Pivac, N., Muck-Šeler, D. & Švob Štrac, D. (2020) HTR1A, HTR1B, HTR2A, HTR2C and HTR6 Gene Polymorphisms and Extrapyramidal Side Effects in Haloperidol-Treated Patients with Schizophrenia.. International journal of molecular sciences, 21 (7), 2345, 15 doi:10.3390/ijms21072345.
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Babić Leko, M., Nikolac Perković, M., Klepac, N., Švob Štrac, D., Borovečki, F., Pivac, N., Hof, P. & Šimić, G. (2020) Relationships of cerebrospinal fluid Alzheimer's disease biomarkers and COMT, DBH, and MAOB single nucleotide polymorphisms. Journal of alzheimers disease, 73 (1), 135-145 doi:10.3233/JAD-190991.
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Tudor, L., Nedić Erjavec, G., Nikolac Perkovic, M., Konjevod, M., Švob Štrac, D., Uzun, S., Kozumplik, O., Jovanovic, T., Lauc, G. & Pivac, N. (2019) N-glycomic Profile in Combat Related Post- Traumatic Stress Disorder. Biomolecules, 9 (12), E834, 16 doi:10.3390/biom9120834.
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Šustar, A., Nikolac Perković, M., Nedić Erjavec, G., Švob Štrac, D. & Pivac, N. (2019) Association between reduced brain-derived neurotrophic factor concentration & coronary heart disease. Indian journal of medical research, 150 (1), 43-49 doi:10.4103/ijmr.IJMR_1566_17.
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Kovačić Petrović, Z., Nedić Erjavec, G., Nikolac Perković, M., Švob Strac, D., Peraica, T., Tudor, L. & Pivac, N. (2019) The association between serotonin transporter polymorphism, platelet serotonin concentration and insomnia in non-depressed veterans with posttraumatic stress disorder. Psychiatria Danubina, 31 (1), 78-87 doi:10.24869/psyd.2019.78.
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Švob Štrac, D., Nedić Erjavec, G., Nikolac Perković, M., Nenadić-Šviglin, K., Konjevod, M., Grubor, M. & Pivac, N. (2019) The association between HTR1B gene rs13212041 polymorphism and onset of alcohol abuse. Neuropsychiatric Disease and Treatment, 15, 339-347 doi:10.2147/NDT.S191457.
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Tudor, L., Konjevod, M., Nikolac Perković, M., Švob Štrac, D., Nedić Erjavec, G., Uzun, S., Kozumplik, O., Šagud, M., Kovačić Petrović, Z. & Pivac, N. (2018) Genetic Variants of theBrain-Derived Neurotrophic Factorand Metabolic Indices in Veterans With Posttraumatic Stress Disorder. Frontiers in psychiatry, 9, 637, 12 doi:10.3389/fpsyt.2018.00637.
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Šagud, M., Tudor, L., Nikolac Perković, M., Uzun, S., Živković, M., Konjevod, M., Kozumplik, O., Vuksan Ćusa, B., Švob Štrac, D., Mihaljević-Peleš, A., Radoš, I., Mimica, N., Nedić Erjavec, G. & Pivac, N. (2018) Haplotypic and genotypic association of catechol-O- methyltransferase rs4680 and rs4818 polymorphisms and treatment resistance in schizophrenia. Frontiers in Pharmacology, 9, 705, 14 doi:10.3389/fphar.2018.00705.
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Šagud, M., Vlatković, S., Švob Štrac, D., Sviben, Mario, živković, Maja, Vilibić, M., Vuksan-Ćusa, B. & Mihaljević- Peleš, Alma, Pivac, Nela (2018) Latent Toxoplasma Gondii infection is associated with decreased serum triglyceride to high-density lipoprotein cholesterol ratio in male patients with schizophrenia. Comprehensive psychiatry, 82, 115-120 doi:.org/10.1016/j.comppsych.2018.02.002.
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Havelka Mestrović, A., Tudor, L., Nikolac Perković, M., Nedić Erjavec, G., Kovačić Petrović, Z., Švob Štrac, D., Konjevod, M. & Pivac, N. (2018) Significant association between catechol-O- methyltransferase (COMT) Val158/108Met polymorphism and cognitive function in veterans with PTSD. Neuroscience letters, 666, 38-43 doi:10.1016/j.neulet.2017.12.033.
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Nikolac Perković, M., Švob Štrac, D., Tudor, L., Konjevod, M., Nedić Erjavec, G. & Pivac, N. (2018) Catechol-O-methyltransferase, Cognition and Alzheimer's Disease. Current Alzheimer research, 15 (5), 408-419 doi:10.2174/1567205015666171212094229.
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Nedić Erjavec, G., Konjevod, M., Nikolac Perković, M., Švob Štrac, D., Tudor, L., Barbas, C., Grune, T., Žarković, N. & Pivac, N. (2018) Short overview on metabolomic approach and redox changes in psychiatric disorders. Redox Biology, 14, 178-186 doi:10.1016/j.redox.2017.09.002.
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Samardzic, J., Hencic, B., Jancic, J., Jadzic, D., Djuric, M. & Obradovic, I Dragan, Svob Strac, Dubravka (2017) Neurosteroid dehydroepiandrosterone improves active avoidance retrieval and induces antidepressant-like behavior in rats. Neuroscience letters, 660, 17-21 doi:10.1016/j.neulet.2017.09.013.
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Hirasawa-Fujita, M., Tudor, L., Nikolac Perković, M., Kozumplik, O., Nedić Erjavec, G., Uzun, S., Švob Štrac, D., Konjevod, M., Mimica, N., Domino, E. & Pivac, N. (2017) Genotypic and haplotypic associations of catechol-O-methyltransferase (COMT) rs4680 and rs4818 with salivary cortisol in patients with schizophrenia. Psychiatry research, 259, 262-264 doi:10.1016/j.psychres.2017.10.037.
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Nedić Erjavec, G., Uzun, S., Nikolac Perković, M., Kozumplik, O., Švob Strac Dubravka, Mimica, N., Hirasawa-Fujita, M., Domino, E. & Pivac, N. (2017) Cortisol in schizophrenia : No association with tobacco smoking, clinical symptoms or antipsychotic medication. Progress in neuro-psychopharmacology & biological psychiatry, 77, 228-235 doi:10.1016/j.pnpbp.2017.04.032.
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Nikolac Perković, M., Nedić Erjavec, G., Švob Štrac, D., Uzun, S., Kozumplik, O. & Pivac, N. (2017) Theranostic Biomarkers for Schizophrenia. International journal of molecular sciences, 18 (4), 733, 37 doi:10.3390/ijms18040733.
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Erhardt, J. & Švob Štrac, D. (2016) Non-Pharmacological Tools for Neuroenhancement Neuroethical Issues. Synthesis philosophica, 31 (1), 181-194 doi:10.21464/sp31113.
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Di Giovanni, G., Švob Štrac, D., Sole, M., Unzeta, M., Tipton, K., Muck Šeler, D., Bolea, I., Della Corte, L., Nikolac Perković, M., Pivac, N., Smolders, I., Stasiak, A., Fogel, W. & De Deurwaerdère, P. (2016) Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases. Frontiers in Neuroscience, 10, 541-1 doi:10.3389/fnins.2016.00541.
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Svob Strac, D., Pivac, N., Smolders, I., Fogel, W., De Deurwaerdere, P. & Di Giovanni, G. (2016) Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs. Frontiers in Neuroscience, 10, 492-1 doi:10.3389/fnins.2016.00492.
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Erhardt, J. & Švob Štrac, D. (2016) New Tools For Neuroenhancement - What About Ethics. Croatian medical journal, 57 (4), 392-394 doi:10.3325/cmj.2016.57.392.
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Šagud, M., Nikolac Perković, M., Vuksan-Ćusa, B., Maravić, A., Švob Štrac, D., Mihaljević Peleš, A., Živković, M., Kušević, Z. & Pivac, N. (2016) A prospective, longitudinal study of platelet serotonin and plasma brain-derived neurotrophic factor concentrations in major depression: effects of vortioxetine treatment. Psychopharmacology, 233 (17), 3259-3267 doi:10.1007/s00213-016-4364-0.
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Švob Štrac, D., Pivac, N. & Mück-Šeler, D. (2016) The serotonergic system and cognitive function. Translational Neuroscience, 7 (1), 35-49 doi:10.1515/tnsci-2016-0007.
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Švob Štrac, D., Kovačić Petrović, Z., Nikolac Perković, M., Umolac, D., Nedić Erjavec, G. & Pivac, N. (2016) Platelet monoamine oxidase type B, MAOB intron 13 and MAOA-uVNTR polymorphism and symptoms of posttraumatic stress disorder. Stress, 19 (4), 362-373 doi:10.1080/10253890.2016.1174849.
doi Šustar, A., Nikolac Perković, M., Nedić Erjavec, G., Švob Štrac, D. & Pivac, N. (2016) A protective effect of the BDNF Met/Met genotype in obesity in healthy Caucasian subjects but not in patients with coronary heart disease. European review for medical and pharmacological sciences, 20 (16), 3417-3426.
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Nikolac Perković, M., Švob Štrac, D., Nedić Erjavec, G., Uzun, Suzana, Podobnik, Josip, Kozumplik, O., Vlatković, S. & Pivac, N. (2016) Monoamine oxidase and agitation in psychiatric patients.. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 69, 131-146 doi:10.1016/j.pnpbp.2016.02.002.
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Švob Štrac, D., Vlainić, J., Samardžić, J., Erhardt Julija & Krsnik, Z. (2016) Effects of acute and chronic administration of neurosteroid dehydroepiandrosterone sulfate on neuronal excitability in mice.. Drug Design Development and Therapy, 10, 1201-1215 doi:10.2147/DDDT.S102102.
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Švob Štrac, D., Nedić Erjavec, G., Nikolac Perković, M., Nenadić Šviglin, K., Borovečki, F. & Pivac, N. (2015) Association of GABA-A receptor α2 subunit gene (GABRA2) with alcohol dependence-related aggressive behavior. Progress in neuro-psychopharmacology & biological psychiatry, 63, 119-125 doi:10.1016/j.pnpbp.2015.06.010.
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Švob Štrac, D., Muck-Šeler, D. & Pivac, N. (2015) Neurotransmitter measures in the cerebrospinal fluid of patients with Alzheimer's disease : a review. Psychiatria Danubina, 27 (1), 14-24.
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Babić, M., Švob Štrac, D., Muck- Šeler, D., Pivac, N., Stanić, G., Hof, P. & Šimić, G. (2014) Update on the core and developing cerebrospinal fluid biomarkers for Alzheimer disease. Croatian medical journal, 55 (4), 347-365 doi:10.3325/cmj.2014.55.347.
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Samardžić, J., Švob Štrac, D., Obradović, M., Oprić, D. & Obradović, D. (2012) DMCM, a benzodiazepine site inverse agonist, improves active avoidance and motivation in the rat.. Behavioural brain research, 235 (2), 195-199 doi:10.1016/j.bbr.2012.07.032.
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Švob Štrac, D., Muck-Šeler, D. & Pivac, N. (2012) The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic pituitary-adrenal axis activity in female rats.. Croatian medical journal, 53 (3), 212-221 doi:10.3325/cmj.2012.53.214.
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Vlainić, J., Švob Štrac, D., Jazvinšćak Jembrek, M., Vlainić, T. & Peričić, D. (2012) The effects of zolpidem treatment on GABAA receptors in cultured cerebellar granule cells: Changes in functional coupling. Life sciences, 90 (23-24), 889-894 doi:10.1016/j.lfs.2012.04.021.
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Švob Štrac, D., Jazvinšćak Jembrek, M., Erhardt, J., Mirković Kos, K. & Peričić, D. (2012) Modulation of recombinant GABA-A receptors by neurosteroid dehydroepiandrosterone sulphate. Pharmacology, 89 (3/4), 163-171 doi:10.1159/000336058.
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Vlainić, J., Jazvinšćak Jembrek, M., Vlainić, T., Švob Štrac, D. & Peričić, D. (2012) Differential effects of short- and long-term zolpidem treatment on recombinant alpha 1 beta 2 gamma 2s subtype of GABA(A) receptors in vitro. Acta pharmacologica Sinica, 33 (12), 1469-1476 doi:10.1038/aps.2012.89.
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Vlainić, J., Jazvinšćak Jembrek, M., Švob Štrac, D. & Peričić, D. (2010) The effects of zolpidem treatment and withdrawal on the in vitro expression of recombinant alpha1beta2gamma2s GABA-A receptors expressed in HEK 293 cells. Naunyn-Schmiedeberg's archives of pharmacology, 382 (3), 201-212 doi:10.1007/s00210-010-0539-0.
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Švob Štrac, D., Vlainić Lazić, J., Jazvinšćak Jembrek, M. & Peričić Danka (2008) Differential effects of diazepam treatment and withdrawal on recombinant GABAA receptor expression and functional coupling. Brain research, 1246, 29-40 doi:10.1016/j.brainres.2008.09.093.
doi Jazvinšćak Jembrek, M., Švob Štrac, D., Vlainić Lazić, J. & Peričić, D. (2008) The role of transcriptional and translational mechanisms in flumazenil-induced up-regulation of recombinant GABAA receptors. Neuroscience Research, 61 (3), 234-241.
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Peričić, D., Vlainić Lazić, J. & Švob Štrac Dubravka (2008) Sedative and anticonvulsant effects of zolpidem in adult and aged mice. Journal of neural transmission, 115 (6), 795-802 doi:10.1007/s00702-008-0020-0.
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Peričić, D., Švob Štrac, D. & Vlainić Lazić, J. (2007) Interaction of diazepam and swim stress. Brain research, 1184, 81-87 doi:10.1016/j.brainres.2007.09.039.
doi Peričić, D. & Švob Štrac, D. (2007) The role of 5-HT7 receptors in the control of seizures. Brain Research, 1141, 48-55.
Peričić, D., Švob Štrac, D., Jazvinšćak Jembrek, M. & Vlainić Lazić, J. (2007) Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1 beta2 gamma2s subunits of GABA-A receptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 375 (3), 177-187.
Peričić, D., Švob Štrac, D. & Vlainić (Lazić), J. (2006) Zimelidine decreases seizure susceptibility in stressed mice. Journal of Neural Transmission, 113 (12), 1863-1871.
Peričić, D., Lazić, J. & Švob Štrac, D. (2005) Chronic treatment with flumazenil enhances binding sites for convulsants at recombinant alpha1 beta2 gamma2s GABA-A receptors. Biomedicine & pharmacotherapy, 59 (7), 408-414.
Peričić, D., Lazić, J. & Švob Štrac, D. (2005) Anticonvulsant effects of acute and repeated fluoxetine treatment in unstressed and stressed mice. Brain research, 1033 (1), 90-95.
Peričić, D., Lazić, J., Jazvinšćak Jembrek, M. & Švob Štrac, D. (2005) Stimulation of 5-HT1A receptors increases the seizure threshold for picrotoxin in mice. European Journal of Pharmacology, 527 (1-3), 105-110.
Peričić, D., Jazvinšćak Jembrek, M., Švob Štrac, D., Vlainić (Lazić), J. & Rajčan Špoljarić, I. (2005) Enhancement of benzodiazepine binding sites following chronic treatment with flumazenil. European Journal of Pharmacology, 507 (1-3), 7-13.
Peričić, D., Lazić, J., Jazvinšćak Jembrek, M., Švob Štrac, D. & Rajčan, I. (2004) Chronic exposure of cells expressing recombinant GABA A receptors to benzodiazepine antagonist flumazenil enhances the maximum number of benzodiazepine binding sites. Life Sciences, 76 (3), 303-317.
Peričić, D., Švob Štrac, D., Jazvinšćak Jembrek, M. & Rajčan, I. (2003) Prolonged exposure to gamma-aminobutyric acid up-regulates stably expressed recombinant alpha1 beta2 gamma2s GABA A receptors. European Journal of Pharmacology, 482, 117-125.
Peričić, D. & Švob, D. (2002) Interaction of stress and noradrenergic drugs in the control of picrotoxin-induced seizures. Epilepsy Research, 51 (1-2), 179-187.
Peričić, D., Švob, D., Jazvinšćak Jembrek, M. & Mirković Kos, K. (2001) The involvement of alpha(2)-adrenoceptors in the anticonvulsive effect of swim stress in mice. Psychopharmacology, 158 (1), 87-93.
Peričić, D., Jazvinšćak, M., Švob, D. & Mirković, K. (2001) Swim stress alters the behavioural response of mice to GABA-related and some GABA-unrelated convulsants. Epilepsy research, 43 (2), 145-152.
Peričić, D., Jazvinšćak, M., Švob, D. & Mirković, K. (2000) Beta-1 adrenoceptor antagonists potentiate the anticonvulsive effect of swim stress in mice. Pharmacology Biochemistry and Behavior, 67 (3), 507-510.
Peričić, D., Švob, D., Jazvinšćak, M. & Mirković, K. (2000) Anticonvulsive effect of swim stress in mice. Pharmacology biochemistry and behavior, 66 (4), 879-886.
Conference proceedings papers
Scientific conference proceedings papers
Švob Štrac, D., Čačev, T. & Žarković, N. (2014) Project of Stress Center Establishment. U: Šiber, G. (ur.)Scientific and Professional Conference with International Participation Management- Conference Proceedings.
Babić, M., Švob Štrac, D., Mück- Šeler, D., Pivac, N. & Šimić, G. (2014) Pathogenesis and early diagnosis of Alzheimer’s disease: involvement of the monoaminergic system. U: Di Giovanni, G. (ur.)Xjenza.
Theses
Doctoral dissertation
Švob Štrac, D. (2007) 'Plasticity of GABA-A receptors: Adaptive changes of recombinant GABA-A receptors in cell culture as a response to chronic exposure to diazepam', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.
Master thesis
Švob Štrac, D. (2004) 'Regulation of recombinant GABA A receptors in cell culture by chronic drug treatment', magistarski rad, Prirodoslovno-matematički fakultet, Zagreb.
Membership in professional associations / societies
Croatian Pharmacological Society
Croatian Society for Biochemistry and Molecular Biology
Croatian Biological Society
Croatian Society for Neuroscience
Croatian Laboratory Animal Science Association