Dr. Marijana Radić Stojković
HR-10000, Zagreb
Education
B. Sc. Degree: “Method for hard chain typing of monoclonal immunoglobulins”, in research group of Prof. Dr. sc. I. Basic, Biology Department, Faculty of Science and Mathematics, University of Zagreb,1998.
2001-2009 Postgraduate study of Organic Chemistry, Chemistry Department, Faculty of Science and Mathematics, University of Zagreb.
Ph. D. degree: “Synthesis of urea-phenanthridinium derivatives and their interactions with nucleic acids in aqueous media”, Supervisor: Dr.sc. I. Piantanida, 2009.
Projects
HrZZ IP-2018-01-4694 "Molecular recognition of DNA:RNA hybrid and multistranded structures in bioanalytical and in vitro systems"
HAZU 2018 "12 DNA and RNA targets + 6 bio-inspired derivatives of lignans = 1 paper (graduate + scientific (Wos Q1))"
Classes
- 2018/2019 Guest lecturer, course "Physiological Effects of Plant Compounds and Extracts" (with Prof. Dr. Sandra Radić Brkanac); the Graduate University Study of Experimental Biology, Faculty of Science, University of Zagreb
- Postgraduate studies of Chemistry, Course: "Stereochemistry" (Faculty of Science, Organic Chemistry, with Prof. dr. sc. Mladen Žinić)
Publications
Books and book chapters
Book chapters
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Grienke, U., Radić Brkanac, S., Vujčić, V., Urban, E., Ivanković, S., Stojković, R., Rollinger, M., Kralj, J., Brozović, A. & Radić Stojković, M. (2019) Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From Centaurea ragusina L.. U: Hohmann, J., Karolina Kiss, A., Rollinger, J. & Atanasov, A. (ur.) Ethnopharmacology in Central and Eastern Europe in the Context of Global Research Developments. Lausanne, Frontiers Media, str. 20-58 doi:10.3389/fphar.2018.00972.
doiwww.frontiersin.org
Journal articles
Scientific and review papers
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González-García, J., Galiana, C., Dea-Ayuela, M., Radić Stojković, M., López-Molina, S., Galiana-Roselló, C., Blasco, S., Piantanida, I. & García-España, E. (2023) Impact of the zinc complexation of polytopic polyaza ligands on the interaction with double and single stranded DNA/RNA and antimicrobial activity. Dalton transactions, 52, 5478-5485 doi:10.1039/d3dt00395g.
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Matić, J., Tandarić, T., Radić Stojković, M., Šupljika, F., Karačić, Z., Tomašić Paić, A., Horvat, L., Vianello, R. & Tumir, L. (2023) Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme. Beilstein journal of organic chemistry, 19, 550-565 doi:10.3762/bjoc.19.40.
doiwww.beilstein-journals.orgfulir.irb.hr -
Fabijanić, I., Kurutos, A., Tomašić Paić, A., Tadić, V., Kamounah, F., Horvat, L., Brozovic, A., Crnolatac, I. & Radić Stojković, M. (2023) Selenium-Substituted Monomethine Cyanine Dyes as Selective G-Quadruplex Spectroscopic Probes with Theranostic Potential. Biomolecules, 13 (1), 128, 20 doi:10.3390/biom13010128.
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Rep, V., Štulić, R., Koštrun, S., Kuridža, B., Crnolatac, I., Radić Stojković, M., Čipčić Paljetak, H., Perić, M., Matijašić, M. & Raić-Malić, S. (2022) Novel tetrahydropyrimidinyl-substituted benzimidazoles and benzothiazoles: synthesis, antibacterial activity, DNA interactions and ADME profiling. RSC Medicinal Chemistry, 13 (12), 1504-1525 doi:10.1039/d2md00143h.
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Zonjić, I., Kurutos, A., Mihovilović, P., Crnolatac, I., Tumir, L., Tomašić Paić, A., Kralj, J., Horvat, L., Brozovic, A., Stojković, R. & Radić Stojković, M. (2022) Formation of triplex rA/dA-containing nucleic acid helices induced by new thiazole orange analogues and their biological evaluation. H-aggregate formation conditioned by rA sequence. Dyes and pigments, 207, 110715, 14 doi:10.1016/j.dyepig.2022.110715.
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Zonjić, I., Radić Stojković, M., Crnolatac, I., Tomašić Paić, A., Pšeničnik, S., Vasilev, A., Kandinska, M., Mondeshki, M., Baluschev, S., Landfester, K., Glavaš-Obrovac, L., Jukić, M., Kralj, J., Brozovic, A., Horvat, L. & Tumir, L. (2022) Styryl dyes with N-Methylpiperazine and N-Phenylpiperazine Functionality: AT-DNA and G-quadruplex binding ligands and theranostic agents. Bioorganic chemistry, 127, 105999, 15 doi:10.1016/j.bioorg.2022.105999.
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Zonjić, I., Tumir, L., Crnolatac, I., Šupljika, F., Racané, L., Tomić, S. & Radić Stojković, M. (2022) Recognition of ATT Triplex and DNA:RNA Hybrid Structures by Benzothiazole Ligands. Biomolecules, 12 (3), 1600173, 20 doi:10.3390/biom12030374.
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Maračić, S., Grbčić, P., Shanmugam, S., Radić Stojković, M., Pavelić, K., Sedić, M., Kraljević Pavelić, S. & Raić-Malić, S. (2021) Amidine- and amidoxime-substituted heterocycles: Synthesis, antiproliferative evaluations and DNA binding. Molecules, 26 (22), 7060, 22 doi:10.3390/molecules26227060.
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Racané, L., Rep, V., Kraljević Pavelić, S., Grbčić, P., Zonjić, I., Radić Stojković, M., Taylor, M., Kelly, J. & Raić-Malić, S. (2021) Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles. Journal of enzyme inhibition and medicinal chemistry, 36 (1), 1952-1967 doi:10.1080/14756366.2021.1959572.
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Racané, L., Zlatar, I., Perin, N., Cindrić, M., Radovanović, V., Banjanac , M., Shanmugam, S., Radić Stojković, M., Brajša, K. & Hranjec, M. (2021) Biological activity of newly synthesized benzimidazole and benzothizole 2,5‐disubstituted furane derivatives. Molecules, 26 (16), 4935, 21 doi:10.3390/molecules26164935.
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Lončar, B., Perin, N., Mioč, M., Boček, I., Grgić, L., Kralj, M., Tomić, S., Radić Stojković, M. & Hranjec, M. (2021) Novel amino substituted tetracyclic imidazo[4,5-b]pyridine derivatives: Design, synthesis, antiproliferative activity and DNA/RNA binding study. European journal of medicinal chemistry, 217, 113342, 18 doi:10.1016/j.ejmech.2021.113342.
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Bistrović Popov, A., Krstulović, L., Koštrun, S., Jelić, D., Bokulić, A., Radić Stojković, M., Zonjić, I., Taylor, M., Kelly, J., Bajić, M. & Raić-Malić, S. (2020) Design, synthesis, antitrypanosomal activity, DNA/RNA binding and in vitro ADME profiling of novel imidazoline-substituted 2-arylbenzimidazoles. European journal of medicinal chemistry, 207, 112802, 19 doi:10.1016/j.ejmech.2020.112802.
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Tumir, L., Zonjić, I., Žuna, K., Radić Brkanac, S., Jukić, M., Huđek, A., Durgo, K., Crnolatac, I., Glavaš-Obrovac, L., Cardullo, N., Pulvirenti, L., Muccilli, V., Tringali, C. & Radić Stojković, M. (2020) Synthesis, DNA/RNA-interaction and biological activity of benzo[k,l]xanthene lignans. Bioorganic chemistry, 104, 104190, 12 doi:10.1016/j.bioorg.2020.104190.
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Meščić Macan, A., Perin, N., Jakopec, S., Mioč, M., Radić Stojković, M., Kralj, M., Hranjec, M. & Raić-Malić, S. (2020) Synthesis, antiproliferative activity and DNA/RNA-binding properties of mono- and bis-(1,2,3-triazolyl)-appended benzimidazo[1,2-a]quinoline derivatives. European journal of medicinal chemistry, 185, 111845, 11 doi:10.1016/j.ejmech.2019.111845.
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Matić, J., Šupljika, F., Tandarić, T., Dukši, M., Piotrowski, P., Vianello, R., Brozović, A., Piantanida, I., Schmuck, C. & Radić Stojković, M. (2019) DNA/RNA recognition controlled by the glycine linker and the guanidine moiety of phenanthridine peptides. International journal of biological macromolecules, 134, 422-434 doi:10.1016/j.ijbiomac.2019.05.063.
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Panić, M., Radić Stojković, M., Kraljić, K., Škevin, D., Radojčić Redovniković, I., Gaurina Srček, V. & Radošević, K. (2019) Ready-to-use green polyphenolic extracts from food by-products. Food chemistry, 283, 628-636 doi:10.1016/j.foodchem.2019.01.061.
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Grienke, U., Radić Brkanac, S., Vujčić, V., Urban, E., Ivanković, S., Stojković, R., Rollinger, J., Kralj, J., Brozović, A. & Radić Stojković, M. (2018) Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From Centaurea ragusina L.. Frontiers in Pharmacology, 9, 972, 15 doi:10.3389/fphar.2018.00972.
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Radić Stojković, M., Gonzalez-Garcia, J., Šupljika, F., Galiana-Rosello, C., Guijarro, L., Gazze, S., Francis, L., Piantanida, I. & Garcia- Espana, E. (2018) Specific and highly efficient condensation of GC and IC DNA by polyaza pyridinophane derivatives. International journal of biological macromolecules, 109, 143-151 doi:10.1016/j.ijbiomac.2017.11.156.
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Saftić, D., Radić Stojković, M., Žinić, B., Glavaš-Obrovac, L., Jukić, M., Piantanida, I. & Tumir, L. (2017) Impact of linker between triazolyl-uracil and phenanthridine on recognition of DNA and RNA. Recognition of uracil – containing RNA.. New journal of chemistry, 41 (22), 13240-13252 doi:10.1039/C7NJ02699D.
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Vujčić, V., Radić Brkanac, S., Radojčić Redovniković, I., Ivanković, S., Stojković, R., Žilić, I. & Radić Stojković, M. (2017) Phytochemical and Bioactive Potential of in vivo and in vitro Grown Plants of Centaurea ragusina L. – Detection of DNA/RNA Active Compounds in Plant Extracts via Thermal Denaturation and Circular Dichroism. Phytochemical analysis, 28 (6), 584-592 doi:10.1002/pca.2708.
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Knežević Teofilović, N., Bihi, M., Radić Stojković, M., Tumir, L., Ester, K., Kralj, M., Majhen, D., Oršolić, N., Lepur, A., Vrbanec, D., Markotić, A., Dembić, Z., Weber, A., Piantanida, I., Vugrek, O., Diken, M. & Knežević, J. (2017) 1-ethyl-3-(6-methylphenanthridine-8-il) urea modulates TLR3/9 activation and induces selective pro-inflammatory cytokine expression in vitro. Bioorganic & medicinal chemistry letters, 27 (7), 1530-1537 doi:10.1016/j.bmcl.2017.02.048.
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Li, M., Radić Stojković, M., Ehlers, M., Zellermann, E., Piantanida, I. & Schmuck, C. (2016) Use of an Octapeptide-Guanidiniocarbonylpyrrole Conjugate for the Formation of a Supramolecular beta-Helix that Self-Assembles into pH-Responsive Fibers. Angewandte Chemie. International edition, 55 (42), 13015-13018 doi:10.1002/anie.201605522.
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Steiner, I., Stojanović, N., Bolje, A., Brozović, A., Polančec, D., Ambriović-Ristov, A., Radić Stojković, M., Piantanida, I., Eljuga, D., Košmrlj, J. & Osmak, M. (2016) Discovery of ‘click’ 1, 2, 3-triazolium salts as potential anticancer drugs. Radiology and oncology, 50 (3), 280-288 doi:10.1515/raon-2016-0027.
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Radić, S., Vujčić, V., Glogoški, M. & Radić-Stojković, M. (2016) Influence of pH and plant growth regulators on secondary metabolite production and antioxidant activity of Stevia rebaudiana (Bert). Periodicum biologorum, 118 (1), 9-19 doi:10.18054/pb.2016.118.1.3420.
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Matić, J., Tumir, L., Radić Stojković, M. & Piantanida, I. (2016) Advances in peptide-based DNA/RNA-intercalators. Current protein & peptide science, 17 (2), 127-134 doi:10.2174/138920371702160209124439.
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Kaźmierska, A., Gryl, M., Stadnicka, K., Sieroń, L., Eilmes, A., Matković, M., Radić-Stojković, M., Piantanida, I. & Eilmes, J. (2015) Dicationic derivatives of dinaphtotetraaza[14]annulene: Synthesis, crystal structures and the preliminary evaluation of their DNA binding properties. Tetrahedron, 71 (24), 4163-4173 doi:10.1016/j.tet.2015.04.098.
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Gershberg, J., Radić Stojković, M., Škugor, M., Tomić, S., Rehm, T., Rehm, S., Saha-Möller, C., Piantanida, I. & Würthner, F. (2015) Sensing of Double-Stranded DNA/RNA Secondary Structures by Water Soluble Homochiral Perylene Bisimide Dyes. Chemistry - A European Journal, 21 (21), 7886-7895 doi:10.1002/chem.201500184.
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Radić Stojković, M., Piotrowski, P., Schmuck, C. & Piantanida, I. (2015) A Short, rigid linker between pyrene and guanidiniocarbonyl-pyrrole induced new set of spectroscopic responses to ds-DNA secondary structure. Organic & biomolecular chemistry, 13, 1629-1633 doi:10.1039/c4ob02169j.
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Tumir, L., Radić Stojković, M. & Piantanida, I. (2014) Come-back of phenanthridine and phenanthridinium derivatives in 21st century. Beilstein journal of organic chemistry, 10, 2930-2954 doi:10.3762/bjoc.10.312.
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Radić Stojković, M., Škugor, M., Dudek, Ł., Grolik, J., Eilmes, J. & Piantanida, I. (2014) Molecular recognition of AT-DNA sequences by the induced CD pattern of dibenzotetraaza[14]annulene (DBTAA) - adenine derivatives. Beilstein journal of organic chemistry, 10, 2175-2185 doi:10.3762/bjoc.10.225.
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Racane, L., Stojković, R., Tralić- Kulenović, V., Cerić, H., Đaković, M., Ester, K., Mišir Krpan, A. & Radić Stojković, M. (2014) Interactions with polynucleotides and antitumor activity of amidino and imidazolinyl substituted 2-phenylbenzothiazole mesylates. European journal of medicinal chemistry, 86, 406-419 doi:10.1016/j.ejmech.2014.08.072.
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Radić Stojković, M., Škugor, M., Tomić, S., Grabar, M., Smrečki, V., Dudek, Ł., Grolik, J., Eilmes, J. & Piantanida, I. (2013) Dibenzotetraaza[14]annulene – adenine conjugate recognizes complementary poly dT among ss-DNA / ss-RNA sequences. Organic & biomolecular chemistry, 11 (24), 4077-4085 doi:10.1039/c3ob40519b.
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Miljanić, S., Dijanošić, A., Kalac, M., Radić Stojković, M., Piantanida, I., Pawlica, D. & Eilmes, J. (2012) Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides. Croatica chemica acta, 85 (4), 577-584 doi:10.5562/cca2106.
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Rehm, T., Radić Stojković, M., Rehm, S., Škugor, M., Piantanida, I. & Würthner, F. (2012) Interaction of Spermine-Alanine Functionalized Perylene Bisimide Dye Aggregates with ds-DNA/RNA Secondary Structure. Chemical Science, 3 (12), 3393-3397 doi:10.1039/c2sc20825c.
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Miljanić, S., Dijanošić, A., Landeka, K., Radić Stojković, M. & Piantanida, I. (2012) Binding of a phenanthridine-biguanide derivative with DNA/RNA polynucleotides studied by surface-enhanced Raman spectroscopy (SERS). Applied spectroscopy, 66 (1), 82-89 doi:10.1366/11-06411.
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Klemm, K., Radić Stojković, M., Horvat, G., Tomišić, V., Piantanida, I. & Schmuck, C. (2012) Interactions of multicationic bis-guanidiniocarbonyl pyrrole receptors with double stranded nucleic acids. Chemistry : a European journal, 18 (5), 1352-1363 doi:10.1002/chem.201101544.
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Radić Stojković, M., Miljanić, S., Mišković, K., Glavaš-Obrovac, L. & Piantanida, I. (2011) The phenanthridine biguanides efficiently differentiate between dGdC, dAdT and rArU sequences by two independent, sensitive spectroscopic methods. Molecular biosystems, 7 (5), 1753-1765 doi:10.1039/C1MB05030C.
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Radić Stojković, M., Marczi, S., Glavaš-Obrovac, L. & Piantanida, I. (2010) Permanent positive charge strongly influences DNA/RNA binding and antiproliferative activity of urea-phenanthridinium conjugates. European journal of medicinal chemistry, 45 (8), 3281-3292 doi:10.1016/j.ejmech.2010.04.006.
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Radić Stojković, M., Marjanović, M., Pawlica, D., Dudek, L., Eilmes, J., Kralj, M. & Piantanida, I. (2010) Cationic side-chains control DNA/RNA binding properties and antiproliferative activity of dicationic dibenzotetraaza[14]annulene derivatives. New journal of chemistry, 34 (3), 500-507 doi:10.1039/b9nj00490d.
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Pawlica, D., Radić Stojković, M., Dudek, Ł., Piantanida, I., Sieroń, L. & Eilmes, J. (2009) New dicationic derivatives of dibenzotetraaza[14]annulene: tuning of the DNA/RNA binding properties. Tetrahedron, 65 (20), 3980-3989 doi:10.1016/j.tet.2009.03.030.
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Radić Stojković, M. & Piantanida, I. (2008) Tuning urea-phenanthridinium conjugates for DNA/RNA and basepair recognition. Tetrahedron, 64 (33), 7807-7814 doi:10.1016/j.tet.2008.05.142.
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Radić Stojković, M., Piantanida, I., Kralj, M., Marjanović, M., Žinić, M., Pawlica, D. & Eilmes, J. (2007) The dicationic derivatives of DBTAA. Interactions with DNA/RNA and antiproliferative effects on human cell lines. Bioorganic & medicinal chemistry, 15 (4), 1795-1801 doi:10.1016/j.bmc.2006.11.034.
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Pawlica, D., Radić Stojković, M., Sieron, L., Piantanida, I. & Eilmes, J. (2006) Synthesis, crystal structures and the preliminary evaluation of the new dibenzotetraaza[14]annulene-based DNA/RNA binding agents. Tetrahedron, 62 (39), 9156-9165 doi:10.1016/j.tet.2006.07.045.
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Molčanov, K., Radić Stojković, M., Piantanida, I. & Žinić, M. (2006) Conformational axial chirality of phenyl N-[2-(acetylamido)biphenyl-4-yl]carbamate. Acta crystallographica. Section E, Structure reports online, 62 (7), o2666-o2668 doi:10.1107/S1600536806020125.
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Radić, S., Radić-Stojković, M. & Pevalek-Kozlina, B. (2006) Influence of NaCl and mannitol on peroxidase activity and lipid peroxidation in Centaurea ragusina L. roots and shoots. Journal of plant physiology, 163 (12), 1284-1292 doi:10.1016/j.jplph.2005.08.019.
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Membership in professional associations / societies
Croatian Chemical Society