Dr. Ana Tomašić Paić
Division of Organic Chemistry and Biochemistry
Laboratory for Protein Biochemistry and Molecular Modelling
10000 Zagreb
Croatia
Education
- 2016 higher expert associate
- 2015 postdoctoral researcher on ESF (European Social Fund) project "Strengthening capacity in medicinal chemistry and the study of bioactive systems", Laboratory for Study of Interactions of Biomacromolecules, Institute Rudjer Boskovic
- 2013 Senior Research Associate in the field of Molecular Biotechnology, Faculty of Food Technology and Biotechnology, University of Zagreb (Croatia)
- 2011 Research Associate in the field of Molecular Biotechnology, Faculty of Food Technology and Biotechnology, University of Zagreb (Croatia)
- 2010 PhD thesis : "The Role of proteins TLP40 and TROL in the regulatory mechanisms of oxygenic photosynthesis" (mentor: Prof Dr Hrvoje Fulgosi, Institute Rudjer Boskovic)
- 2006-2015 Laboratory for electronic microscopy (Institute Rudjer Boskovic, Zagreb)
- 2004-2006 Laboratory for chemical biology (Institute Rudjer Boskovic, Zagreb)
- 2002-2004 Doctoral studies in Nutrition (Food toxicology), Faculty of Food Technology and Biotechnology, University of Zagreb (Croatia)
- 2002 Master of Biotechnology Thesis : "Interaction between Dodecylammonium Chloride and i-Carrageenan" (thesis was performed at the Institute Rudjer Boskovic)
- Master’s degree studies in Biotechnology, Faculty of Food Technology and Biotechnology, University of Zagreb (Croatia)
Awards and Achievements
- November 2, 2011: Poster Presentation Prize of the Bayer Crop Science at the Conference “Plant Organellar Signaling” from 31/August – 3/November 2011 in Primošten, Croatia
Featured Publications
Puthiyaveetil, S., Ibrahim, I. M, Jelicic, B., Tomasic, A., Fulgosi, H., Allen, J. F. (2010) Transcriptional control of photosynthesis genes: the evolutionarily conserved regulatory mechanism in plastid genome function.Genome biology and evolution. 2; 888-896
Lepedus, H., Tomasic, A., Juric, S., Katanic, Z., Cesar, V., Fulgosi, H. (2009) Photochemistry of PSII in CYP38 Arabidopsis thaliana Mutant.Food Technol. Biotechnol47(3): 275-280
Juric, S., Hazler-Pilepic, K., Tomasic, A., Lepedus, H., Jelicic, B., Puthiyaveetil, S., Bionda, T., Vojta, L., Allen, J. F., Schleiff, E., Fulgosi, H. (2009) Tethering of ferredoxin:NADP+ oxidoreductase to thylakoid membranes is mediated by novel chloroplast protein TROL.PlantJ. 60(5): 783-794
Tomasic, A., Bertosa B., Tomic, S., Soskic M., Magnus V. (2007) Binding behavior of amino acid conjugates of indole-3-acetic acid to immobilized human serum albumin. J. Chromatogr. A.1154: 240–249
Publications
Journal articles
Scientific and review papers
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Matić, J., Tandarić, T., Radić Stojković, M., Šupljika, F., Karačić, Z., Tomašić Paić, A., Horvat, L., Vianello, R. & Tumir, L. (2023) Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme. Beilstein journal of organic chemistry, 19, 550-565 doi:10.3762/bjoc.19.40.
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Fabijanić, I., Kurutos, A., Tomašić Paić, A., Tadić, V., Kamounah, F., Horvat, L., Brozovic, A., Crnolatac, I. & Radić Stojković, M. (2023) Selenium-Substituted Monomethine Cyanine Dyes as Selective G-Quadruplex Spectroscopic Probes with Theranostic Potential. Biomolecules, 13 (1), 128, 20 doi:10.3390/biom13010128.
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Karačić, Z., Šupljika, F., Tomić, A., Brkljačić, L., Tomašić Paić, A., Ćehić, M. & Tomić, S. (2022) Neuropeptides, substrates and inhibitors of human dipeptidyl peptidase III, experimental and computational study — A new substrate identified. International journal of biological macromolecules, 220, 1390-1401 doi:10.1016/j.ijbiomac.2022.09.119.
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Zonjić, I., Kurutos, A., Mihovilović, P., Crnolatac, I., Tumir, L., Tomašić Paić, A., Kralj, J., Horvat, L., Brozovic, A., Stojković, R. & Radić Stojković, M. (2022) Formation of triplex rA/dA-containing nucleic acid helices induced by new thiazole orange analogues and their biological evaluation. H-aggregate formation conditioned by rA sequence. Dyes and pigments, 207, 110715, 14 doi:10.1016/j.dyepig.2022.110715.
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Zonjić, I., Radić Stojković, M., Crnolatac, I., Tomašić Paić, A., Pšeničnik, S., Vasilev, A., Kandinska, M., Mondeshki, M., Baluschev, S., Landfester, K., Glavaš-Obrovac, L., Jukić, M., Kralj, J., Brozovic, A., Horvat, L. & Tumir, L. (2022) Styryl dyes with N-Methylpiperazine and N-Phenylpiperazine Functionality: AT-DNA and G-quadruplex binding ligands and theranostic agents. Bioorganic chemistry, 127, 105999, 15 doi:10.1016/j.bioorg.2022.105999.
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Matić, S., Tomašić Paić, A., Sobočanec, S., Pinterić, M., Pipalović, G., Martinčić, M., Matovina, M. & Tomić, S. (2022) Interdisciplinary study of the effects of dipeptidyl-peptidase III cancer mutations on the KEAP1-NRF2 signaling pathway. International journal of molecular sciences, 23 (4), 1994, 15 doi:10.3390/ijms23041994.
doiwww.mdpi.comwww.ncbi.nlm.nih.govfulir.irb.hr -
Vojta, L., Tomašić Paić, A., Horvat, L., Rac, A., Lepeduš, H. & Fulgosi, H. (2019) Complex lumenal immunophilin AtCYP38 influences thylakoid remodelling in Arabidopsis thaliana. Journal of plant physiology, 243, 153048, 5 doi:10.1016/j.jplph.2019.153048.
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Ban, Ž., Žinić, B., Matković, M., Tomašić Paić, A., Crnolatac, I. & Piantanida, I. (2019) Pyrrolocytosine-pyrene conjugates as fluorescent and CD probes for a fine sensing of ds- polynucleotide secondary structure and specific recognition of poly G. New journal of chemistry, 43, 8204-8214 doi:10.1039/C8NJ05286G.
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Sabljić, I., Tomin, M., Matovina, M., Sučec, I., Tomašić Paić, A., Tomić, A., Abramić, M. & Tomić, S. (2018) The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity. PLoS One, 13 (2), e0192488, 25 doi:10.1371/journal.pone.0192488.
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Kurutos, A., Orehovec, I., Tomašić Paić, A., Crnolatac, I., Horvat, L., Gadjev, N., Piantanida, I. & Deligeorgiev, T. (2018) New series of non-toxic DNA intercalators, mitochondria targeting fluorescent dyes. Dyes and pigments, 148, 452-459 doi:10.1016/j.dyepig.2017.09.049.
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Tomašić Paić, A. & Fulgosi, H. (2016) Chloroplast immunophilins. Protoplasma, 253 (2), 249-258 doi:10.1007/s00709-015-0828-z.
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Tomašić Paić, A. (2012) Properties of cannabinoid receptors in medicinal plant Cannabis sativa. Medicinski vjesnik, 44 (1-4), 147-162.
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Zechmann, B., Liou, L., Koffler, B., Horvat, L., Tomašić Paić, A., Fulgosi, H. & Zhang, Z. (2011) Subcellular distribution of glutathione and its dynamic changes under oxidative stress in the yeast Saccharomyces cerevisiae. Fems yeast research, 11 (8), 631-642 doi:10.1111/j.1567-1364.2011.00753.x.
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Puthiyaveetil, S., Ibrahim, I., Jeličić, B., Tomašić, A., Fulgosi, H. & Allen, J. (2010) Transcriptional control of photosynthesis genes: the evolutionarily conserved regulatory mechanism in plastid genome function. Genome biology and evolution, 2, 888-896 doi:10.1093/gbe/evq073.
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Zechmann, B., Tomašić, A., Horvat, L. & Fulgosi, H. (2010) Subcellular distribution of glutathione and cysteine in cyanobacteria. Protoplasma, 246 (1-4), 65-72 doi:10.1007/s00709-010-0126-8.
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Jurić, S., Hazler-Pilepić, K., Ana Tomašić, A., Lepeduš, H., Jeličić, B., Puthiyaveetil, S., Bionda, T., Vojta, L., Allen, J., Schleiff, E. & Fulgosi, H. (2009) Tethering of ferredoxin : NADP+ oxidoreductase to thylakoid membranes is mediated by novel chloroplast protein TROL. Plant journal, 60 (5), 783-794 doi:10.1111/j.1365-313X.2009.03999.x.
doi Lepeduš, H., Tomašić, A., Jurić, S., Katanić, Z., Cesar, V. & Fulgosi, H. (2009) Photochemistry of PSII in CYP38 Arabidopsis thaliana deletion mutant. Food Technology and Biotechnology, 47 (3), 275-280.
Tomašić, A., Bertoša, B., Tomić, S., Šoškić, M. & Magnus, V. (2007) Binding behavior of amino acid conjugates of indole-3-acetic acid to immobilized human serum albumin. Journal of Chromatography. A, 1154 (1-2), 240-249.
Tomašić, V., Tomašić, A., Šmit, I. & Filipović-Vinceković, N. (2005) Interactions in Mixed Cationic Surfactants and Dextran Sulfate Aqueous Solutions. Journal of colloid and interface science, 285, 342-350.
Gojmerac, T., Pleadin, J., Palković, M. & Tomašić, A. (2004) Anabolics in animal breeding. Veterinarska stanica, 35 (4), 159-165.
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Tomašić, V., Tomašić, A. & Filipović-Vinceković, N. (2002) Interactions between Dodecylammonium Chloride and Jota-Carrageenan. Journal of colloid and interface science, 256, 462-471 doi:10.1006/jcis.2002.8687.
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Conference proceedings papers
Scientific conference proceedings papers
Fulgosi, H., Jurić, S., Tomašić, A. & Lepeduš, H. (2009) Deficiency of TROL protein causes changes in chloroplast morphogenesis. U: Pabst, M. & Zellnig, G. (ur.)Proceedings from the First Joint Meeting of Dreiländertagung and Multinational Congress on Microscopy, Vol.2.
Gojmerac, T., Koršić, M., Žurić, M., Tomašić, A., Barač, I. & Vinković, B. (2004) SERUM LH AND FSH RESPONSE TO SINGLE INTRAVENOUS ADMINISTRATION OF GnRH IN GILTS. U: Bossow, H., Blaha, T. & Pahlitzsch, C. (ur.)Proceedings of the 18th International Pig Veterinary Society Congress..
Membership in professional associations / societies
- Croatian Society of Biochemistry and Molecular Biology
- 2012 DAAD stipendy entitled “Research grant for doctoral candidates and young academics and scientists” at the Christian –Albrechts University of Kiel
- 2011 associate on DAAD or Croatian-German bilateral project: „Control of plant growth and senescence by the energy status of chloroplasts”