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Dr. Anamaria Brozović

President of the Ethics Committee
Senior scientist

A

B

Telephone
+385 1 456 1145
Internal phone number
1545
1877
Academic title
Assistant Professor
Address
Rudjer Boskovic Institute
Bijenicka 54
10000 Zagreb
Croatia

Education

  • 1999-2002 Ph.D., Molecular Biology, Faculty of Science, University of Zagreb, Zagreb, Croatia
  • 1997-1999 M.S., Faculty of Science, University of Zagreb, Zagreb, Croatia
  • 1992-1996 Biology, University of Zagreb, Faculty of Science, Zagreb, Croatia
Additional, certificate education:
  • 2013 Stanford Advanced Project Management Certificate Program, Stanford University, Stanford, USA
  • 2013 Stanford Ignite, Stanford Graduate School of Business-Academic Program for Innovation and Entrepreneurship, Stanford University, Stanford, USA
Research experience
  • 2023- Senior Scientist, Ruđer Bošković Institute, Zagreb, Croatia
  • 2019 Institute of Toxicology, University of Düsseldorf, Germany (invited scientist-COST Action STSM)
  • 2018 Max Planck Institute for Infectious Biology (visiting scientist, EMBO Fellowship), Berlin, Germany
  • 2014-2023 Senior Research Associate, Ruđer Bošković Institute, Zagreb, Croatia
  • 2011-2014 Consulting Assistant Professor, Stanford University, USA
  • 2008-2013 Research Associate, Ruđer Bošković Institute, Zagreb, Croatia
  • 2002-2007 Senior Research Assistant, Ruđer Bošković Institute, Zagreb, Croatia
  • 2002 Postdoctoral stay at the Department of Applied Toxicology, University of Mainz, Germany
  • 1999-2001 PhD student at the Department of Applied Toxicology, University of Mainz, Germany
  • 1997-1999 M.Sc. student, Ruđer Bošković Institute, Zagreb, Croatia

Research Areas

Specific research interests

Projects

Project leader:

  • 2023-2027 "ACAIS-The orchestration of acquired ovarian cancer invasiveness in a stem cell-supporting environment"-Croatian Science Foundation
  • 2023-2025 "Application of core-shell structured nano drug carrier in the multimodal therapy of ovarian cancer"-Large-Scale Croatian-Chinese Scientific Cooperation, Ministry of Science and Education (co-leader Prof. Dr. Wei Zhang, Dalian University of Technology, China)
  • 2017-2021 "DEvOuT-Drug-induced epithelial-mesenchymal transition in ovarian cancer therapy"- Croatian Science Foundation
  • 2018-2019 "Fishing „the miRNA“ in order to target drug-induced epithelial-mesenchymal transition in ovarian cancer"- Bilateral scientific-research cooperation of the Ministry of Science and Education (co-leader Prof. Dr. Zoran Culig University Innsbruck)
  • 2018-2019 "When old drugs get new shape: cisplatin and statin"- Bilateral scientific-research cooperation of the Ministry of Science and Education (co-leader Prof. Dr. Janez Košmrlj University Ljubljana)
  • 2018 "Ovarian cancer organoids as a model for investigation of drug-induced epithelial-mesenchymal transition" EMBO
  • 2016 "Novel organometallic compounds - potential antitumor drugs"- Terry Fox Foundation-donation
  • 2012-2014 "Complexes of platinum and diazecarboxamide as potential cytostatics"- Bilateral scientific-research cooperation of the Ministry of Science, Education and Sports (co-leader Prof. Dr. Janez Košmrlj University Ljubljana)

Project associate:

  • 2018-2022 "Molecular recognition of DNA:RNA hybrid and multistranded structures in bioanalytical and in vitro systems"-Croatian Science Foundation (leader: PhD Marijana Radić Stojković)
  • 2007-2011 "Cell response to cytotoxic agents and resistance development"-Ministry of Science, Education and Sports (leader: PhD Maja Osmak)
  • 2002-2006 "Cellular response to physical, chemical and biological noxes"-Ministry of Science, Education and Sports (leader: PhD Maja Osmak)
  • 1996-2002 "Cell response to genotoxic agents"-Ministry of Education (leader: PhD Maja Osmak)
  • 2012-2013 "Platinum compounds: cellular response and mechanisms of resistance"-Bilateral scientific-research cooperation of the Ministry of Science and Education (leaders: PhD Maja Osmak and Prof. Dr. Gerhard Fritz, University Düsseldorf, Germany)
  • 2010-2011 "Comparison of the effects of ZD0473 and cisplatin"-Bilateral scientific-research cooperation of the Ministry of Science and Education (leaders: PhD Maja Osmak and Doc. Dr. Beate Köberle, University in Mainz, Germany)
  • 2009-2010 "Diaryltriazene-a new group of potential antitumor drugs"-Bilateral scientific-research cooperation of the Ministry of Science and Education (leaders: PhD Maja Osmak and Prof. Dr. Janez Košmrlj, University in Ljubljana, Slovenia)
  • 2008-2009 "Molecular mechanisms determining cellular sensitivity to platinum compounds"-Bilateral scientific-research cooperation of the Ministry of Science and Education (leaders: PhD Maja Osmak and Prof. Dr. Bernd Kaina, University in Mainz, Germany)

COST Actions:

  • CA22125 (2023-2027)- COST Action “Precision medicine in biliary tract cancer”-secondary proposer
  • CA21154 (2022-2026)- COST Action TRANSLACORE “Translational control in cancer European Network”-member
  • CA18117 (2019-2023)- COST Action GYNOCARE “European network for gynaecological rare cancer research: From Concept to Cure”-member
  • CA17104 (2018-2022)- COST Action STRATAGEM  "New diagnostic and therapeutic tools against multidrug resistant tumors"-MC member

Awards and Achievements

  • 2020 Annual Award of Ruđer Bošković Institute for a best scientific paper 2019, Croatia
  • 2018 Annual Award of Ruđer Bošković Institute for a best scientific paper 2017, Croatia
  • 2012 Annual Award of Ruđer Bošković Institute for a patent US 8,217,022, Croatia
  • 2004 Prize “Željko Trgovčević” for the best young scientist publication of the year, Croatia
  • 2004 Poster Prize, ELSO 2004, Nice, France

Classes

  • 2021- External Associate, Medical Studies, Croatian Catholic University, Croatia (principal lecturer Prof. Dr. Tomislav Domazet Lošo)
  • 2017- Principal Lecturer Assistant Professor, Interdisciplinary Postgraduate Study of Molecular Biosciences, University of Osijek, Osijek, Croatia
  • 2017- External Associate, Faculty of Dental Medicine, University of Zagreb, Croatia (principal lecturer Prof. Dr. Ivana Miletić)
  • 2015- Principal Lecturer, Faculty of Science, University of Zagreb, Croatia

Publications

Stručni rad

  • Ambriović Ristov, Andreja ; Brozović, Anamaria | Trajne kulture stanica // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 71-77-x

  • Brozović, Anamaria ; Ambriović Ristov, Andreja | Kloniranje i odabir stanica // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 78-83-x

  • Brozović, Anamaria | Metoda elektroforeze pojedinačne stanice u agaroznom gelu (Comet Assay) // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 216-220-x

  • Brozović, Anamaria | Metode određivanja koncentracije proteina // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 555-560-x

  • Brozović, Anamaria | Višestruko korištenje membrane za imunodetekciju // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 594-595-x

  • Brozović, Anamaria | Utvrđivanje apoptoze korištenjem fluorescein diacetata i propidij jodida // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 793-795-x

  • Brozović, Anamaria ; Furčić, Ivana | Metoda određivanja kompleksa DNA i proteina na temelju zaostajanja u gelu (EMSA) // Metode u molekularnoj biologiji / Ambriović Ristov, Andreja ; Brozović, Anamaria ; Bruvo Mađarić, Branka et al. (ur.). Zagreb: Institut Ruđer Bošković, 2007. str. 220-228

Ostalo

Izvorni znanstveni rad

Izvorni znanstveni rad

Pregledni rad (znanstveni)

Pismo uredniku

Sažetak izlaganja sa skupa

Izvorni znanstveni rad

Ostalo

  • Zonjić, Iva; Tumir, Lidija-Marija; Kralj, Juran; Brozović, Anamaria; Radić Stojković, Marijana | RECOGNITION OF DNA STRUCTURES BY A SERIES OF PHENANTHRIDINE DERIVATIVES // IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry: Book of Abstracts. Louvain-la-Neuve, Wallonia, Belgium: European Federation for Medicinal chemistry and Chemical biology (EFMC), 2023. str. 350-350

  • Zonjić, Iva; Tumir, Lidija-Marija; Kralj, Juran; Brozović, Anamaria; Radić Stojković, Marijana | RECOGNITION OF DNA STRUCTURES BY A SERIES OF PHENANTHRIDINE DERIVATIVES // 10th EFMC Young Medicinal Chemist`s Symposium: Book of Abstracts. Louvain-la-Neuve, Belgium: European Federation for Medicinal chemistry and Chemical biology (EFMC), 2023. str. 108-108

Patents

Theses

Doctoral dissertation

  • Brozović, A. (2002) 'Molecular mechanisms of apoptosis and DNA damage repair involved in cell-sensitivity to cisplatin', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.

Master thesis

  • Brozović, A. (1999) 'Induction of Heat shock proteins in cells after treatment with cytostatics or hyperthermia', magistarski rad, Prirodoslovno-matematički, Zagreb.

Membership in professional associations / societies

  • Croatian Association for Cancer Research
  • American Association for Cancer Research
  • Croatian Society of Biochemistry and Molecular Biology
  • Croatian Genetic Society
Awarded grants, fellowships and specializations:
  • 2019 Cost Action CA17104-STSM
  • 2018 EMBO Scholarship
  • 1999-2000 German Academic Exchange Service (DAAD) Scholarship
  • 1999-2000 Karlovac County Scholarship
  • 1997-2010 Several travel scholarships (granted from: ECDO, FEBS, ELSO, MZOŠ)
  • 1994-1996 University of Zagreb Scholarship (PhD scholarship)
  • 1994-1996 Scholarship of City Karlovac
  • 2019 Institute for Toxicology, University of Düsseldorf, Düsseldorf, Germany (invited scientist, 6 weeks)
  • 2018 Max Planck Institute for Infection Biology, Berlin, Germany (visitor scientist; two months)
  • 2017 Institute of Toxicology University of Düsseldorf, Germany (visitor scientist; one month)
  • 2011-2014 Department of Oncology Stanford University, USA (Consulting Assistant Professor)
  • 2008-2011 several one-month stays (bilateral HR-DE projects)
  • 2002 Institute of Toxicology University of Mainz, Germany (postdoc)
  • 1992-2001 Institute of Toxicology University of Mainz, Germany (PhD)
Organization skills, committees and boards:
  • 2023- Member of the Committee of Doctoral Study Molecular Biosciences, University of Osijek
  • 2021- Member of the Ethical Committee, Ruđer Bošković Institute
  • 2018- Member of the Committee of Doctoral Study of Biology, Faculty of Science, University of Zagreb
  • 2018-2022 Member of the Management Committee COST Action CA17104 STRATAGEM
  • 2011- Member of the Advisory Board of the Croatia Scholarship Fund (USA)
  • 2015-2016 Member of the Committee for RBI Doctoral Study establishment
  • 2016- OnkoLab business consultant j.d.o.o.
  • 2016-2018 Technical and technological monitoring consultant within IRCRO program No. IR_2015_27 (HAMAG-BICRO) BioGnost d.o.o.
  • 2007 One of the editors of the book "Methods in Molecular Biology", published by the Ruđer Bošković Institute, Zagreb
  • 2004 Editor of the abstract book "2nd Scientific Symposium with International Participation 45 Years of Molecular Biology in Croatia 50 Years of Double Helix", Zagreb
  • 2002-2008 Representative of researchers up to 33 years of age Division of Molecular Biology Council, RBI
  • 1998-1999 Head of the Croatian Natural History Society's section "Young Researchers"

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