The DATACROSS project of the Scientific Center of Excellence for Data Science and Cooperative Systems explores advanced methods and technologies in data science and cooperative systems within the horizontal theme ICT of the Croatian S3 in order to support the development of innovation and competitiveness of the Croatian economy in all five thematic priority areas of the S3. By employing more than 40 new research projects, it will enable the implementation of globally relevant scientific research and the transfer of knowledge and technologies with a long-term contribution to the Croatian research sector, the economy and society as a whole.