Croatian healthcare system is faced with the lack of access to smart digital solutions for health data management and AI-based support for informed decision-making, as well as a shortage of digitally empowered medical staff capable of using AI-based digital health solutions. To address this gap, AI4Health.Cro will offer a comprehensive support to businesses and public entities with advanced AIbased services and technologies, addressing the current needs of the healthcare and public health systems for digital transformation. Specifically, AI4Health.Cro will offer services related to (i) digital health innovation development, (ii) testing of AI-based solutions and standards in strategic topics in digital healthcare, (iii) providing education in AI and HPC for healthcare and medicine, as well as in business and innovation skills. Furthermore, through networking, AI4Health.Cro will actively collaborate with other EDIHs, relevant networks, initiatives and other stakeholders to facilitate digital transformation of healthcare system and organizations, SMEs and small mid-caps, through digital skills training and improved access to advanced digital services, ensuring the needed support throughout the EU. In this way, AI4Health.Cro will play a brokering role between health organizations and companies to develop and uptake AI-based digital health solutions. This role is further supported by the Digital Transformation Accelerator (DTA) for matchmaking, training and capacity building.