The EU-funded ENTRANCE project aims to develop and validate a comprehensive user-based toolbox for the risk-based non-intrusive inspection of cross-border freight movements, particularly at the EU Customs Union borders. The aim of this toolbox is to enhance the capabilities of border security practitioners, shielding against a wide range of dangerous and illicit materials with minimum disruption in the cross-border flow of goods. The ENTRANCE toolbox will be validated at the EU Customs Union borders by five practitioner-led field trials that will be chosen for their relevance, strategic position and feasibility.