The main goal of this project is to stimulate the development of novel fusion materials in Croatia; starting with their syntheses and structural characterization to the measurement of mechanical and electrical properties. Selected materials will be evaluated for fusion application by simultaneous bombardment by heavy ions and He ions in advanced Dual-Beam Ion Irradiation Facility for Fusion Materials (DiFU), constructed at our Institute specifically for the study of fusion materials as one of only a dozen worldwide. We will concentrate on the synthesis of materials and study of dual ion beam irradiation effects on: (1) W-based multicomponent alloys (3-6 components), prepared by multi-target magnetron sputtering (MTMS) as high flux materials in fusion reactors; (2) spinel-based dielectric ceramics, prepared by chemical syntheses as functional material and (3) Eurofer steel, which will be purchased as structural material for study in DiFU. Machine learning methods, based on our experimental results, will be applied to optimize the syntheses procedures to obtain the best candidates for fusion application. Advanced techniques will be applied for material characterization, including atomic resolution (S)TEM.Deposition by MTMS, as a high-throughput method, will give us more freedom in choice of the elemental composition and element ratios in multicomponent W-based alloys. Choices of elements to obtain the best properties for fusion application will be made on the basis of a data-driven computational search. A similar approach will be used to select cations to be introduced in the crystalline structure of spinel. Moreover, as a method of choice for the structural study of ceramics, we will install a Raman spectroscopy probe in the DiFU irradiation chamber and validate its functionality to perform in-situ Raman study of ceramics under dual ion beam. If the installation and measurements are successful, it will be the first dual beam irradiation facility with in-situ Raman.