Global warming and the associated climate changes are a serious threat to agricultural production and biodiversity in the world. Drought and heat stress tend to occur together and pose the greatest obstacles to crop production and food security. It is therefore crucial to understand the mechanisms of plant tolerance to abiotic stress. This project focuses on the role that Brassicaceae-specific modifications of indole metabolism, including auxins and indole glucosinolates, play in tolerance to abiotic stresses (drought and heat, individually and combined). Both indole metabolites are involved in the response to abiotic stress, although their role in tolerance mechanisms has not yet been systematically investigated. The project will integrate field research, functional genetics, physiology, biochemistry, transcriptomics and targeted metabolomics. We expect to identify genes and metabolites, responsible for the enhanced tolerance of wild Brassica species to climate changes and contribute to a better understanding of the complex mechanisms of stress tolerance.