Dr. Vilko Smrečki
NMR Centre
Bijenička 54
HR-10000 Zagreb
Croatia
Education
Qualification awarded: Ph. D. in Chemistry
Organisation providing education: University of Zagreb
Date: July 07, 1998
Qualification awarded: M. Sc. in Chemistry
Organisation providing education: Faculty of Science, University of Zagreb
Date: December 20, 1994
Qualification awarded: B. Sc. in Chemistry
Organisation providing education: Faculty of Science, University of Zagreb
Date: July 03, 1990
Projects
2022-2025: PI of a project for RBI (Horizon Europe - HORIZON-INFRA; 101058595): Remote NMR: Moving NMR infrastructures to remote access capabilities - R-NMR
2018-2022: collaborator in a project Multichromophore probes for recognition of particular DNA, RNA and protein structures (CSF 5475, PI: I. Piantanida)
2014-2018: collaborator in a project Multifunctional molecular sensing of DNA/RNA secondary structure by chemical sensors (CSF 1477, PI: I. Piantanida)
2010-2011: collaborator in a bilateral Slovenian-Croatian project NMR Study of the Interactions of Angiotensin II Receptor Antagonists (MSES/MHEST, PI: M. Vinković)
2008-2009: PI of a bilateral Austrian-Croatian project Multi-Field Experimental High Resolution NMR Studies with Applications to Bioactive Compounds (MSES/ÖAD)
2007-2013: collaborator in a project NMR Spectroscopy and Modelling of Bioactive Molecules (MSES 098-0982929-2917, PI: D. Plavšić)
2006-2007: collaborator in a bilateral Austrian-Croatian project NMR Methods for Structural Analysis of Peptidoconjugates (MSES/ÖAD, PI: D. Vikić-Topić)
2004-2005: PI of a bilateral Austrian-Croatian project Spectroscopic and Quantum Chemical Study of Models for Biomolecular Interactions (MSES/ÖAD)
2003-2004: collaborator in an IT project Web Server with Individual Approach to Data Base and Separated Local Network with Applications for Providing Services to NMR (MSES, PI: M. Stipčević)
2003: PI of a bilateral Austrian-Croatian project Multi-Dimensional Nuclear Magnetic Resonance Spectroscopy of Biomolecules (MSES/ÖAD)
2002-2006: collaborator in a project Nuclear Magnetic Resonance and Calculations of Bioorganic Molecules (MSES 0098059, PI: D. Vikić-Topić)
2002-2003: PI of a project Structural Dependence of Nuclear Magnetic Resonance Chemical Shift Anisotropy in Proteins by Quantum Chemical Simulations in the Meitner programme of the Austrian Science Fund (FWF) (M 677)
1998: PI of a project Spectroscopic Study of Push-Pull Stilbenes
(MST 098403, project for young scientists)
1997-1998: collaborator in a bilateral USA-Croatian project Vibrational Analysis of Stilbene and Its Derivatives in Relation to Their Photophysics and Photochemistry (MST/NSF JF-124, PI: G. Baranović)
1996-2000: collaborator in a bilateral Hungarian-Croatian project Investigation of Molecular Structure and Dynamics using Spectroscopic and Quantum-Chemical Methods (CASA 10, PI: Z. Meić)
1996-2000: collaborator in a project Isotope labelling and molecular spectroscopies
(MST 00980802, PI: Z. Meić)
1991-1995: collaborator in a bilateral Hungarian-Croatian project Investigation of Chemical Structure using Spectroscopic and Theoretical Methods (CASA 10, PI: Z. Meić)
1991-1995: collaborator in a project Isotope Effects on Molecular Structure and Dynamics
(MST 1-07-139, PI: Z. Meić)
Awards and Achievements
2020: Ruđer Bošković Institute Award for the best scientific papers published in 2019
Classes
2009-now: Doctoral Study in Chemistry, Analytical Chemistry (Faculty of Science, University of Zagreb) Modern Methods in Structural NMR (elective course, teacher)
2017-now: Postgraduate University (Doctoral) Study of Chemistry of the Mediterranean Environment (Faculty of Chemistry and Technology, University of Split) NMR Spectroscopy in Structure Elucidation of Natural Compounds (elective course, teacher)
2013-2015: Graduate Study in Chemistry (Faculty of Science, University of Zagreb) Organic Chemistry Laboratory 2 (mandatory course, exercise leader)
2012-2013: Undergraduate Study in Molecular Biology (Faculty of Science, University of Zagreb) Organic Chemistry (mandatory course, exercise leader)
2012-2013: Integral Undergraduate and Graduate Study of Physics (Faculty of Science, University of Zagreb) Cell Biophysics (elective course, exercise leader)
1992-1995: Undergraduate Study in Chemistry (Faculty of Science, University of Zagreb) General Chemistry Laboratory 1 (mandatory course, assistant)
Featured Publications
- V. Smrečki, N. Müller, D. Vikić-Topić, P. Vujanić and Z. Meić: "Isotope Effects in 13C NMR Spectra of Monodeuteriated trans-N-Benzylideneaniline", J. Mol. Struct., 348 (1995) 69-72.
- V. Smrečki, P. Novak, D. Vikić‑Topić, T. Hrenar, and Z. Meić: "Deuterium Isotope Effects in 13C NMR Spectra of trans‑N‑Salicylideneaniline Isotopomers", Croat. Chem. Acta, 75 (2002) 41-49.
- V. Sychrovský, N. Müller, B. Schneider, V. Smrečki, V. Špirko, J. Šponer, and L. Trantírek: "Sugar Pucker Modulates the Cross-Correlated Relaxation Rates Across the Glycosidic Bond in DNA", J. Am. Chem. Soc., 127 (2005) 14663-14667.
- W. Schoefberger, V. Smrečki, D. Vikić-Topić, and N. Müller: "Homonuclear Long-Range Correlation Spectra from HMBC-Experiments by Covariance Processing", Magn. Reson. Chem., 45 (2007) 583-589.
- J. Mastelić, I. Jerković, I. Blažević, M. Poljak-Blaži, S. Borović, I. Ivančić-Bace, V. Smrečki, N. Žarković, K. Brčić-Kostić, D. Vikić-Topić, and N. Müller: "A Comparative Study on the Antioxidant and Biological Activities of Carvacrol, Thymol and Eugenol Derivatives", J. Agric. Food Chem., 56 (2008) 3989-3996.
- M. Nausner, J. Schlagnitweit, V. Smrečki, X. Yang, A. Jerschow, and N. Müller: "Nonlinearity and frequency shifts of nuclear magnetic spin-noise", J. Magn. Reson., 198 (2009) 73-79.
- I. Kopriva, I. Jerić, and V. Smrečki: "Extraction of multiple pure component 1H and 13C NMR spectra from two mixtures: novel solution obtained by sparse component analysis-based blind decomposition", Anal. Chim. Acta, 653 (2009) 143-153.
- C. Kosanović, K. Havancsák, B. Subotić, V. Svetličić, T. Mišić Radić, Á. Cziráki, G. Huhn, I. Buljan, and V. Smrečki: "Study of the mechanism of formation of nano-crystalline zeolite X in heterogeneous system",Micropor. Mesopor. Mater., 142 (2011) 139-146.
- A. Maršavelski, V. Smrečki, R. Vianello, M. Žinić, A. Moguš-Milanković, and A. Šantić: "Supramolecular Ionic-Liquid Gels with High Ionic Conductivity", Chem. Eur. J., 21 (2015) 12121-12128.
- S. Bosnar, T. Antonić Jelić, J. Bronić, M. Dutour Sikirić, S. Šegota, V. Čadež, V. Smrečki, A. Palčić and B. Subotić: „Deep Insights into the Processes Occurring during Early Stages of the Formation and Room‑Temperature Evolution of the Core (Amorphous SiO2)@Shell (Organocations) Nanoparticles“, J. Phys. Chem. C, 122 (2018) 9441−9454.
- K. Vlahoviček-Kahlina, M. Vazdar, A. Jakas, V. Smrečki and I. Jerić: „Synthesis of Glycomimetics by Diastereoselective Passerini reaction“, J. Org. Chem., 83 (2018) 13146-13156.
- S. Bosnar, M. Dutour Sikirić, V. Smrečki, J. Bronić, S. Šegota, V. Strasser, T. Antonić Jelić, A. Palčić and B. Subotić: „Controlled aggregation of the core(amorphous silica)@shell(TPA+-polysilicates) nanoparticles at room temperature by selective removal of TPA+ ions from the nanoparticle shell“, Inorg. Chem. Front., 6 (2019) 1639-1653.
- D. Jakšić, M. Šegvić Klarić, I. Crnolatac, N. Šijaković Vujičić, V. Smrečki, M. Górecki, G. Pescitelli and I. Piantanida: “Unique Aggregation of Sterigmatocystin in Water Yields Strong and Specific Circular Dichroism Response Allowing Highly Sensitive and Selective Monitoring of Bio-Relevant Interactions”, Mar. Drugs, 17 (2019) 629-645.
- S. Opačak, D. Babić, B. Perić, Ž. Marinić, V. Smrečki, B. Pem, I. Vinković Vrček and S. I. Kirin: „A ferrocene-based pseudopeptide chiroptical switch“, Dalton Trans., 50 (2021) 4504-4511.
- D. Raljević, J. Parlov Vuković, V. Smrečki, Lj. Marinić Pajc, P. Novak, T. Hrenar, T. Jednačak, L. Konjević, B. Pinević, T. Gašparac: „Machine learning approach for predicting crude oil stability based on NMR spectroscopy“, Fuel, 305 (2021) 121561(1-7).
Publications
Books and book chapters
Book chapters
Novak, P., Vikić-Topić, D., Smrečki, V. & Meić, Z. (2000) Isotope effects in NMR spectra as a structural tool for organic molecules. U: Atta-Ur-Rahman (ur.) New advances in analytical chemistry. Amsterdam, Hrvatska akademija znanosti i umjetnosti (HAZU), str. 135-168.
Journal articles
Scientific and review papers
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Raljević, D., Parlov Vuković, J., Smrečki, V., Marinić Pajc, L., Novak, P., Hrenar, T., Jednačak, T., Konjević, L., Pinević, B. & Gašparac, T. (2021) Machine learning approach for predicting crude oil stability based on NMR spectroscopy. Fuel (Guildford), 305, 121561, 7 doi:10.1016/j.fuel.2021.121561.
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Opačak, S., Babić, D., Perić, B., Marinić, Ž., Smrečki, V., Pem, B., Vinković Vrček, I. & Kirin, S. (2021) A ferrocene-based pseudopeptide chiroptical switch. Dalton transactions, 13, 4504-4511 doi:10.1039/D1DT00508A.
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Parlov Vuković, J., Novak, P., Jednačak, T., Kveštak, M., Kovačević, D., Smrečki, V., Mikulandra, I., Djetelić Ibrahimpašić, M., Glanzer, S. & Zangger, K. (2020) Magnetic field influence on asphaltene aggregation monitored by diffusion NMR spectroscopy: Is aggregation reversible at high magnetic fields?. Journal of dispersion science and technology, 41 (2), 179-187 doi:10.1080/01932691.2018.1561302.
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Jakšić, D., Šegvić Klarić, M., Crnolatac, I., Šijaković Vujičić, N., Smrečki, V., Górecki, M., Pescitelli, G. & Piantanida, I. (2019) Unique Aggregation of Sterigmatocystin in Water Yields Strong and Specific Circular Dichroism Response Allowing Highly Sensitive and Selective Monitoring of Bio-Relevant Interactions. Marine drugs, 17 (11), 629, 17 doi:10.3390/md17110629.
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Bosnar, S., Dutour Sikirić, M., Smrečki, V., Bronić, J., Šegota, S., Strasser, V., Antonić Jelić, T., Palčić, A. & Subotić, B. (2019) Controlled aggregation of the core(amorphous silica)@shell(TPA+ - polysilicates) nanoparticles at room temperature by selective removal of TPA+ ions from the nanoparticle shell. Inorganic Chemistry Frontiers, 6 (7), 1639-1653 doi:10.1039/c9qi00200f.
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Vlahoviček-Kahlina, K., Vazdar, M., Jakas, A., Smrečki, V. & Jerić, I. (2018) Synthesis of Glycomimetics by Diastereoselective Passerini Reaction. Journal of organic chemistry, 83 (21), 13146-13156 doi:10.1021/acs.joc.8b01874.
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Bosnar, S., Antonić Jelić, T., Bronić, J., Dutour Sikirić, M., Šegota, S., Čadež, V., Smrečki, V., Palčić, A. & Subotić, B. (2018) Deep Insights into the Processes Occurring during Early Stages of the Formation and Room-Temperature Evolution of the Core (Amorphous SiO2)@Shell (Organocations) Nanoparticles. Journal of physical chemistry. C, 122 (17), 9441-9454 doi:10.1021/acs.jpcc.8b00024.
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Maršavelski, A., Smrečki, V., Vianello, R., Žinić, M., Moguš-Milanković, A. & Šantić, A. (2015) Supramolecular Ionic-Liquid Gels with High Ionic Conductivity. Chemistry : a European journal, 21 (34), 12121-12128 doi:10.1002/chem.201500887.
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Djaković, S., Kodrin, I., Smrečki, V., Novak, P., Mihalić, Z., Žiher, D., Lapić, J. & Rapić, V. (2014) 1'-Acetylferrocene Amino Acid Esters and Amides. A simple model for parallel beta-helical peptides. Tetrahedron, 70 (14), 2330-2342 doi:10.1016/j.tet.2014.02.047.
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Veljković, J., Antol, I., Basarić, N., Smrečki, V., Molčanov, K., Müller, N. & Mlinarić-Majerski, K. (2013) Atropisomerism in 1-(2-Adamantyl)naphthalene Derivatives. Journal of molecular structure, 1046, 101-109 doi:10.1016/j.molstruc.2013.04.027.
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Radić Stojković, M., Škugor, M., Tomić, S., Grabar, M., Smrečki, V., Dudek, Ł., Grolik, J., Eilmes, J. & Piantanida, I. (2013) Dibenzotetraaza[14]annulene – adenine conjugate recognizes complementary poly dT among ss-DNA / ss-RNA sequences. Organic & biomolecular chemistry, 11 (24), 4077-4085 doi:10.1039/c3ob40519b.
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Reith, L., Schlagnitweit, J., Smrečki, V., Knoer, G., Mueller, N. & Schoefberger, W. (2011) Determination of 3J(1H3′-31P) couplings in a DNA oligomer with enhanced sensitivity employing a constant-time TOCSY difference experiment. Magnetic resonance in chemistry, 49 (3), 125-128 doi:10.1002/mrc.2729.
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Kosanović, C., Havenscak, K., Subotić, B., Svetličić, V., Mišić Radić, T., Cziraki, A., Huhn, G., Buljan, I. & Smrečki, V. (2011) Study of the mechanism of formation of nano-crystalline zeolite X in heterogeneous system. Microporous and mesoporous materials, 142 (1), 139-146 doi:10.1016/j.micromeso.2010.11.027.
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Biljan, I., Cvjetojević, G., Smrečki, V., Novak, P., Mali, G., Plavec, J., Babić, D., Mihalić, Z. & Vančik, H. (2010) Nitrosobenzene Cross-dimerization: Structural Selectivity in Solution and in Solid State. Journal of molecular structure, 979 (1-3), 22-26 doi:10.1016/j.molstruc.2010.05.034.
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Nausner, M., Schlagnitweit, J., Smrečki, V., Yang, X., Jerschow, A. & Müller, N. (2009) Nonlinearity and frequency shifts of nuclear magnetic spin-noise. Journal of magnetic resonance (San Diego, Calif.), 198 (1), 73-79 doi:10.1016/j.jmr.2009.01.019.
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Novak, P., Pičuljan, K., Hrenar, T. & Smrečki, V. (2009) Structure and Hydrogen Bonding Interactions in Methoxysalicylaldehyde Thiosemicarbazone Derivatives in Solution by NMR and DFT Methods. Croatica chemica acta, 82 (2), 477-483.
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Halasz, I., Biljan, I., Novak, P., Meštrović, E., Plavec, J., Mali, G., Smrečki, V. & Vančik, H. (2009) Cross-dimerization of nitrosobenzenes in solution and in solid state. Journal of molecular structure, 918 (1-3), 19-25 doi:10.1016/j.molstruc.2008.07.035.
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Kopriva, I., Jerić, I. & Smrečki, V. (2009) Extraction of multiple pure component 1H and 13C NMR spectra from two mixtures: novel solution obtained by sparse component analysis-based blind decomposition. Analytica chimica acta, 653 (2), 143-153 doi:10.1016/j.aca.2009.09.019.
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Mastelić, J., Jerković, I., Blažević, I., Poljak-Blaži, M., Borović, S., Ivančić-Baće, I., Smrečki, V., Žarković, N., Brčić-Kostić, K., Vikić-Topić, D. & Mueller, N. (2008) A comparative study on the antioxidant and biological activities of carvacrol, thymol and eugenol derivatives. Journal of agricultural and food chemistry, 56 (11), 3989-3996 doi:10.1021/jf073272v.
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Jakas, A., Vinković, M., Smrečki, V., Šporec, M. & Horvat, Š. (2008) Fructose induced N-terminal glycation of enkephalins and related peptides. Journal of Peptide Science, 14 (8), 936-945 doi:10.1002/psc.1029.
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Schoefberger, W., Smrečki, V., Vikić- Topić, D. & Müller, N. (2007) Homonuclear long-range correlation spectra from HMBC experiments by covariance processing. Magnetic resonance in chemistry, 45 (7), 583-589 doi:10.1002/mrc.2013.
doi Sychrovsky, V., Mueller, N., Schneider, B., Smrečki, V., Špirko, V., Šponer, J. & Trantirek, L. (2005) Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA. Journal of the American Chemical Society, 127 (42), 14663-14667.
Steindl, C., Schäffer, C., Smrečki, V., Messner, P. & Müller Norbert (2005) The secondary cell wall polymer of Geobacillus tepidamans GS5-97(T): structure of different glycoforms. Carbohydrate research, 340 (14), 2290-2296. (https://www.bib.irb.hr/202669).
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Smrečki, V., Novak, P., Vikić-Topić, D., Hrenar, T. & Meić, Z. (2002) Deuterium isotope effects in C-13 NMR spectra of trans-N-salicylideneaniline isotopomers. Croatica chemica acta, 75 (1), 41-49. (https://www.bib.irb.hr/83822).
fulir.irb.hrhrcak.srce.hr Stepanić, V., Baranović, G. & Smrečki, V. (2001) Structure and vibrational spectra of conjugated acids of trans- and cis-azobenzene. Journal of molecular structure, 569, 89-109.
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Novak, P., Meić, Z., Vikić-Topić, D., Smrečki, V. & Plavec, J. (1998) Structural dependence of isotope effects in H-1 and C-13 NMR spectra of the trans-N-benzylideneaniline imino group. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 54 (2), 327-333 doi:10.1016/S1386-1425(97)00241-2.
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Vikić-Topić, D., Novak, P., Smrečki, V. & Meić, Z. (1997) Deuterium Isotope Effects in C-13 NMR Spectra of trans-Azobenzene. Journal of molecular structure, 410, 5-7 doi:10.1016/S0022-2860(96)09665-2.
doi Smrečki, V., Baranović, G., Keresztury, G. & Meić, Z. (1997) Near-Infrared Fourier Transform Raman Spectra of Protonated and Deuterated trans-Azobenzene Isotopomers. Journal of molecular structure, 408, 405-408.
Meić, Z., Baranović, G., Smrečki, V., Novak, P., Keresztury, G. & Holly, S. (1997) Vibrational Coupling in Trans-Azobenzene and Its Isotopomers. Journal of molecular structure, 408, 399-403.
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Meić, Z., Novak, P., Vikić-Topić, D. & Smrečki, V. (1996) Deuterium Isotope Effects on C-13 Chemical Shifts in cis-Stilbene. Magnetic resonance in chemistry, 34 (1), 36-41 doi:10.1002/(SICI)1097-458X(199601)34:13.0.CO ; 2-9.
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Smrečki, V., Vikić-Topić, D., Meić, Z. & Novak, P. (1996) Deuterium Isotope Effects and Their Nonadditivity in C-13 NMR Spectra of Polydeuteriated trans-N-Benzylideneaniline Isotopomers. Croatica chemica acta, 69 (4), 1501-1509.
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Conference proceedings papers
Scientific conference proceedings papers
Haeubl, M., Nausner, M., Trantírek, L., Smrečki, V., Müller, N. & Schoefberger, W. (2007) NMR Investigations and Supporting ab initio Calculations on Oligonucleotide-Porphyrin Complexes. U: Hochreiter, S., Kueng, J., Palkoska, J. & Wagner, R. (ur.)1st International Conference on Bioinformatics Research and Development.
Meić, Z., Baranović, G., Smrečki, V. & Keresztury, G. (1996) Vibrational Analysis of the Protonated Azo Group. Raman Spectra and Normal Coordinates of Protonated trans-Azobenzene and Its Isotopomers. U: Asher, S. & Stein, P. (ur.)XV International Conference on Raman Spectroscopy. (https://www.bib.irb.hr/7391).
Membership in professional associations / societies
Croatian Chemical Society (since 1987)
American Chemical Society (since 2009)