• Deciphering DNA-Protein Crosslink Repair in vivo using zebrafish model - DNAPRO

  01.02.2018 - 01.02.2023 | 246,997.15 EUR

  CroRISIRB

Original scientific paper

• Otten, Cecile; Kutnjak, Marin; Supina-Pavić, Christine; Antičević, Ivan; Medved, Vanna; Popović, Marta | ACRC/GCNA is an essential protease that repairs DNA-protein crosslinks during vertebrate development // Nucleic acids research, 54 (2026), 7; gkag324, 19. doi: 10.1093/nar/gkag324

  doiacademic.oup.comfulir.irb.hr

• Stojanović, Nikolina ; Dekanić, Ana ; Paradžik, Mladen ; Majhen, Dragomira ; Ferenčak, Kresimir ; Ruščic, Jelena ; Bardak, Irena ; Supina, Christine ; Tomičić, Maja T. ; Christmann, Markus et al. | Differential effects of integrin αv knockdown and cilengitide on sensitisation of triple-negative breast cancer and melanoma cells to microtubule poisons // Molecular pharmacology, 94 (2018), 6; 1334-1351. doi: 10.1124/mol.118.113027

  doidoi.orgfulir.irb.hr

Review article (scientific)

• Supina Pavić, Christine; Horvat, Anđela; Tadijan, Ana; Josić, Janja; Deželjin, Martina; Jazvinšćak Jembrek, Maja; Vlašić, Ignacija; Slade, Neda | The p53 Isoforms as Potential Biomarkers in Different Cancer Entities // International journal of molecular sciences, 27 (2026), 12; 1, 5153. doi: 10.3390/ijms27125153

  doi

Conference abstract

• Otten, Cecile ; Supina, Christine ; Dakic, Valentin ; Anticevic, Ivan ; Popovic, Marta | Using the zebra fi sh as an in vivo model to study the role of P97/Vcp and Sprtn in DNA-Protein Crosslink Repair (DPCR) // Book of Abstracts, “At the Intersection of DNA Replication and Genome Maintenance: from Mechanisms to Therapy”. | Udine, 2022. str. 84-84

• Kutnjak, Marin ; Supina Pavić, Christine ; Otten, Cecile ; Popović, Marta | The role of GCNA (ACRC) protein in the DNA-protein crosslink repair in zebrafish // Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology "HDBMB22: From Science to Knowledge". | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2022. str. 99-99

  congress2022.hdbmb.hr

• Antičević, Ivan ; Lončar, Jovica ; Supina, Christine ; Popović, Marta | Uloga tirozil-DNA-fosfodiesteraza u popravku križno vezanja DNA i proteina in vivo // Knjiga sažetaka SSDS PMF 2020. | Zagreb, 2020. str. 85-85

  www.pmf.unizg.hr

• Antičević, Ivan ; Supina, Christine ; Lončar, Jovica ; Popović, Marta | The role of Tyrosyl-DNA-phosphodiesterases in the repair of DNA-protein crosslinks in vivo. | 2019, 19, 1

Conference abstract

• Kutnjak, Marin; Otten, Cecile; Supina Pavić, Christine; Popović, Marta | ACRC (GCNA) is a conserved DNA-protein crosslink repair protease that cleaves multiple substrates during vertebrate development // FEBS Open Bio, 15, S2, 2025. str. 52-52

  febs.onlinelibrary.wiley.com

• Josić, Janja; Horvat, Anđela; Supina, Christine; Vlašić, Ignacija; Slade, Neda | Expression profilling of p53 family isoforms in targeted therapy-resistant primary melanoma cell lines // Oncology insights, 3, 2025. str. 107-107

  www.sdir.ac.rs

• Otten, Cecile ; Supina, Christine ; Dakic, Valentin ; Anticevic, Ivan ; Popovic, Marta | Investigating the role of the P97/Vcp segregase in DNA-protein crosslink repair (DPCR) in vivo using the zebrafish // FEBS Open Bio, 2022. str. 246-246

  febs.onlinelibrary.wiley.com

• Antičević, Ivan ; Lončar, Jovica ; Supina, Christine ; Popović, Marta | The role of Tyrosyl-DNA-phosphodiesterases in the repair of DNA-protein crosslinks in vivo // FEBS Open Bio, 11, Suppl. 1, 2021. str. 279-279

  www.pmf.unizg.hr

• Stojanović, Nikolina ; Dekanić, Ana ; Paradžik, Mladen ; Majhen, Dragomira ; Ferenčak, Krešimir ; Ruščić, Jelena ; Bardak, Irena ; Supina, Christine ; Tomicic, Maja T. ; Christmann, Markus et al. | Differential effects of integrin αV knockdown and cilengitide on sensitisation of triple-negative breast cancer and melanoma cells to microtubule poisons // Libri oncologici : Croatian journal of oncology, 2018. str. 83-83

  hrcak.srce.hr

Unpublished conference paper

• Horvat, Anđela; Vlašić, Ignacija; Supina Pavić, Christine; Josić, Janja; Dulić, Vjekoslav; Slade, Neda. | Overexpression of ΔNp73α activates checkpoint kinases and promotes tetraploidy in response to DNA damage // The international p53/p63/p73 isoforms workshop in cancer and ageing | Dundee, Ujedinjeno Kraljevstvo, 10.06.2025-13.06.2025

• Kutnjak, Marin; Otten, Cecile; Supina Pavić, Christine; Popović, Marta | ACRC (GCNA) is a conserved DNA-protein crosslink repair protease essential in vertebrate development // EMBO Workshop "Evolution and Diversity of the DNA Damage Response" | Indija, 19.02.2024-23.02.2024

• Kutnjak, Marin ; Supina Pavić, Christine ; Otten, Cecile ; Popović, Marta | GCNA (ACRC) is an essential protease that repairs DNA-protein crosslinks during zebrafish embryonic development // EMBO Workshop "Cell and Developmental Systems" | Arolla, Švicarska, 22.08.2022-26.08.2022

• Kutnjak, Marin ; Supina Pavić, Christine ; Otten, Cecile ; Popović, Marta | GCNA (ACRC) is an essential protease that repairs DNA-protein crosslinks during zebrafish embryonic development // EMBO Workshop "The DNA Damage Response, Immunity and Aging" | Singapur, Singapur, 10.10.2022-13.10.2022

Master's thesis (university)

• Kutnjak, Marin | Uloga proteina ACRC u popravku unakrsnih veza DNA-protein u modelnom organizmu zebrici (Danio rerio) / Popović, Marta; Malenica, Nenad (mentor); Supina, Christine (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2021

  repozitorij.pmf.unizg.hr

• Supina, Christine | Kombinirani utjecaj cilengitida i paklitaksela na stanične linije trostruko negativnog tumora dojke i melanoma / Ambriović-Ristov, Andreja (mentor); Dekanić, Ana (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2018

  zir.nsk.hr

Doctoral thesis

• Supina Pavić, Christine | The role of ACRC protease and nucleotide excision repair pathway in the repair of DNA-protein crosslinks (DPCs) / Popović, Marta (mentor). | Zagreb, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2023

  mobi.unios.hr