• Diagnostic probe for labeling biomolecules in living systems

  01.04.2024 - 31.05.2025 | 66,345.70 EUR

  CroRISIRB

• Natural product-inspired organocatalytic dearomatization strategies - OCADA

  29.12.2023 - 28.12.2027 | 182,719.43 EUR

  CroRISIRB

• RESET principles in design of chiral cyclopentadienyl ligands with adjustable steric elements - RESET

  01.07.2023 - 30.06.2026 | 597,007.08 EUR

  CroRISIRB

• Building and testing the LED-NMR device for monitornig photochemical reactions inside the NMR spectrometer

  24.10.2022 - 23.10.2023 | 265.45 EUR

  CroRISIRB

Original scientific paper

• Purić, Marko; Duplić, Filip; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Zr-Mediated Cyclization of Alkynes as a Transferable Protocol for Constructing C2-Symmetric and Other Chiral Multisubstituted Cyclopentadienyl Ligands // ACS Organic & Inorganic Au, XXXX (2026), XXX; 5c00123, 7. doi: 10.1021/acsorginorgau.5c00123

  doi

• Petrić, Karlo; Čikoš, Ana; Nikšić-Franjić, Ivana; Lloyd-Jones, Guy C.; Gredičak, Matija; Topolovčan, Nikola | Reaction profiling of visible-light-mediated [2+1] dearomatization vs alkylation of electron-rich arenes with aryldiazoacetates: real-time NMR monitoring, kinetics, and computational analysis // Organic chemistry frontiers, 13 (2026), 9; 2794-2804. doi: 10.1039/d6qo00072j

  doipubs.rsc.org

• Gobin, Marko; Topolovčan, Nikola | Design, Synthesis, and Structural Analysis of Binaphthyl‐Based Chiral Benzindenes // Advanced synthesis & catalysis, 368 (2026), 9; e70478, 7. doi: 10.1002/adsc.70478

  doiadvanced.onlinelibrary.wiley.comfulir.irb.hr

• Belovari, Mateja; Pašalić, Lea; Pem, Barbara; Jurković, Marta; Topolovčan, Nikola; Gredičak, Matija; Piantanida, Ivo; Bakarić, Danijela | Search for the smallest switch-on, water soluble and a phase-sensitive fluorimetric probe for lipid membranes: N-aryl isoindolin-1-one core // Microchemical journal, 208 (2025), 112335, 10. doi: 10.1016/j.microc.2024.112335

  doilinkinghub.elsevier.com

• Gobin, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Catalytic haloallylation/Zr-mediated dienyne cyclization/isomerization sequence for tailored cyclopentadiene substitution // Organic chemistry frontiers, 12 (2025), 3; 808-815. doi: 10.1039/d4qo02020k

  doipubs.rsc.orgfulir.irb.hr

• Beriša, Arben; Duplić, Filip; Purić, Marko; Gredičak, Matija; Topolovčan, Nikola | Exploiting 3‐Methyleneisoindolinones as In Situ Generated Reactive Intermediates in the Synthesis of Tetrasubstituted Carbon Center // Asian Journal of Organic Chemistry, 14 (2025), 8; e00562, 5. doi: 10.1002/ajoc.202500562

  doiaces.onlinelibrary.wiley.comfulir.irb.hr

• Topolovčan, Nikola ; Degač, Marina ; Čikoš, Ana ; Gredičak, Matija | Chemoselective and Regioselective Synthesis of Spiroisoindolinone Indenes via an Intercepted Meyer-Schuster Rearrangement/Intramolecular Friedel-Crafts Alkylation Relay // Journal of organic chemistry, 87 (2022), 3712-3717. doi: 10.1021/acs.joc.1c02647

  doipubs.acs.orgdoi.org

• Topolovčan, Nikola ; Duplić, Filip ; Gredičak, Matija | Influence of N-Substitution in 3-Alkyl-3- hydroxyisoindolin-1-ones on the Stereoselectivity of Brønsted Acid-Catalyzed Synthesis of 3- Methyleneisoindolin-1-ones // European journal of organic chemistry, 2021 (2021), 28; 3920-3924. doi: 10.1002/ejoc.202100400

  doichemistry-europe.onlinelibrary.wiley.comfulir.irb.hr

• Topolovčan, Nikola; Hudlický, Tomáš; Nardangeli, Nolan; Thomson, Jared | Total Synthesis of Methyl 1,5,8-Trimethoxy-1H-isochromene-3-carboxylate and Its Derivatives via Palladium-Catalyzed Annulation of 2-Alkynylbenzaldehydes // Synthesis, 53 (2021), 21; 4110-4116. doi: 10.1055/a-1532-8656

  doi

• Glavač, Danijel ; Topolovčan, Nikola ; Gredičak, Matija | Organocatalytic Synthesis of α-Triphenylmethylamines from Diarylketimines and Phenols // Journal of organic chemistry, 85 (2020), 21; 14253-14261. doi: 10.1021/acs.joc.0c02225

  doipubs.acs.orgdoi.org

Review article (scientific)

• Topolovčan, Nikola ; Gredičak, Matija | Synthesis and stereoselective catalytic transformations of 3-hydroxyisoindolinones // Organic & biomolecular chemistry, 19 (2021), 4637-4651. doi: 10.1039/d1ob00164g

  doipubs.rsc.orgdoi.org

Short communication

• Purić, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | An alternative approach to chiral BINOL-Cp ligand synthesis: modification of stereoelectronic properties // Book of Abstracts of 9th Faculty of Science PhD Student Symposium / Petrović, Petra (ur.). | Zagreb: Sveučilište u Zagrebu Prirodoslovno-matematički fakultet, 2025. str. 54-54

  drive.google.com

• Gobin, Marko; Topolovčan, Nikola | Development of chiral benzindenyl ligands // Book of Abstracts of 9th Faculty of Science PhD Student Symposium / Petrović, Petra (ur.). | Zagreb: Sveučilište u Zagrebu Prirodoslovno-matematički fakultet, 2025. str. 45-45

  drive.google.com

• Purić, Marko; Topolovčan, Nikola | Development of method for the synthesis of chiral multisubstituted cyclopentadienyl ligands // Book of Abstracts Summer Conference of Croatian Chemical Society Rijeka - Pula 2024 / Rezić Meštrović, Iva; Vidović, Nikolina; Petković Didović, Mirna et al. (ur.). | Rijeka: Croatian Chemical Society, 2024. str. 15-15

  rijeka-pula-chem.hkd.hrfulir.irb.hr

• Gobin, Marko; Topolovčan, Nikola | Customized multisubstituted cyclopentadienes: innovations in design and synthesis // Book of Abstracts Summer Conference of Croatian Chemical Society Rijeka - Pula 2024 / Rezić Meštrović, Iva; Vidović, Nikolina; Petković Didović, Mirna et al. (ur.). | Rijeka: Croatian Chemical Society, 2024. str. 21-21

  rijeka-pula-chem.hkd.hr

Conference abstract

• Purić, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Chiral multisubstituted BINOL Cp-ligands and their complexes: synthesis and computational analysis // XLIX “A. “Corbella”International Summer School on Organic Synthesis, ISOS 2025: Book of Abstracts. | Gargnano: Società Chimica Italiana (SCI), 2025. str. 160-160

  corbellasummerschool.unimi.it

• Knežević, Marin; Sanderes, Ernest; Gobin, Marko; Topolovčan, Nikola; Barešić, Luka; Čikoš, Ana; Perić, Berislav; Hrenar, Tomica; Kirin, Srećko | Synthesis and characterization of ferrocene peptides // Solid-State Science & Research 2025: Book of Abstracts and Programme / Torić, Filip; Ivšić, Trpimir (ur.). | Zagreb: Ruđer Bošković Institute, 2025. str. 83-83

• Purić, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Chiral Multisubstituted BINOL–Cyclopentadienyl Ligands and Their Complexes with Transition Metals // 29th Croatian Meeting of Chemists and Chemical Engineers with international participationand : 7th Symposium Vladimir Prelog : Book of abstracts / Cindro, Nikola; Kokan, Zoran; Namjesnik, Danijel et al. (ur.). | Zagreb: Croatian Chemical Society, 2025. str. 72-72

  29hskiki.hkd.hr

• Gobin, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Next-gen ligands: precision desgin of chiral benzindenyl frameworks // XLIX “A. “Corbella”International Summer School on Organic Synthesis, ISOS 2025: Book of Abstracts. | Gargnano: Società Chimica Italiana (SCI), 2025. str. 114-114

  corbellasummerschool.unimi.it

• Nikšić-Franjić, Ivana; Purić, Marko; Topolovčan, Nikola | In search for descriptors in chiral Cp-catalysts // Solutions in Chemistry 2024: Book of Abstracts / Kassal, Petar; Meštrović, Ernest; Namjesnik, Danijel et al. (ur.). | Zagreb: Hrvatsko kemijsko društvo, 2024. str. 88-88

  solutionsinchemistry.hkd.hr

• Čikoš, Ana; Petrić, Karlo; Gredičak, Matija; Topolovčan, Nikola | Shedding light on dearomatization of transformable electron-rich arenes with LED-NMR // EUROMAR 2023 : the 19th European Magnetic Resonance Congress 2023, 9-13 July, Glasgow : programme & abstract book / EUROMAR (ur.). | Glasgow: EUROMAR, 2023. str. 477-477

  euromar2023.org

Unpublished conference paper

• Purić, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Chiral Multisubstituted Cyclopentadienyl Ligands for Stereoselective Organometallic Transformations: Design, Synthesis, and Computational Analysis // European Winter School on Physical Organic Chemistry | Bressanone, Italija, 01.02.2026-06.02.2026

• Nikšić-Franjić, Ivana; Lukač, Josip; Purić, Marko; Topolovčan, Marko | Computational Design of Chiral Catalysts // School on Machine Learning for Molecules and Materials Research | Zadar, Hrvatska, 09.06.2025-13.06.2025

• Purić, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | New Insights in Design and Synthesis of Chiral BINOL-Cp Ligands // 25th Tetrahedron Symposium | Brugge, Belgija, 01.07.2025-04.07.2025

• Gobin, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Design of next-generation chiral benzindenyl ligands // European Symposium on Organic Chemistry | Kopenhagen, Danska, 29.06.2025-03.07.2025

• Nikšić-Franjić, Ivana; Purić, Marko; Topolovčan, Marko | Computational Insights into Substituent Effects on the Chiral Cyclopentadienyl Ligand Framework // 22nd International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis | Kyoto, Japan, 01.09.2025-05.09.2025

• Knežević, Marin; Gobin, Marko; Topolovčan, Nikola; Hrenar, Tomica; Kirin, Srećko I. | 1,n’-Ferrocene as turn inducer in amino acid foldamers // International Symposium on Foldamers | London, Ujedinjeno Kraljevstvo, 01.09.2025-03.09.2025

• Knežević, Marin; Gobin, Marko; Topolovčan, Nikola; Kirin, Srećko I. | Ferrocene peptides as models for selective catalysts // 10th Symposium of Chemistry Students | Zagreb, Hrvatska, 10.10.2025-11.10.2025

• Purić, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Alternative Approach to Design and Synthesis of Chiral Multisubstituted BINOL-Cp Ligands // Liblice 2024 – 58th Advances in Organic, Bioorganic and Pharmaceutical Chemistry | Špindlerův Mlýn, Češka Republika, 07.11.2024-09.11.2024

• Gobin, Marko; Nikšić-Franjić, Ivana; Topolovčan, Nikola | Design and Synthesis of Chiral Benzindenyl Ligands // Liblice 2024 – 58th Advances in Organic, Bioorganic and Pharmaceutical Chemistry | Špindlerův Mlýn, Češka Republika, 07.11.2024-09.11.2024

Master's thesis (university)

• Ćaćić, Katarina | Nekovalentne interakcije u regioselektivnom alkiliranju indola / Topolovčan, Nikola (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2025

  repozitorij.pmf.unizg.hr

• Purić, Marko | Razvoj metode za pripravu kiralnih višesupstituiranih ciklopentadienilnih liganada / Topolovčan, Nikola (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2024

  repozitorij.pmf.unizg.hr

• Marko Gobin | Priprava višesupstituiranih ciklopentadiena cirkonocenom potpomognutom ciklizacijom dienina / Nikola Topolovčan (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2023

  repozitorij.pmf.unizg.hr

• Šterpin, David | Priprava višesupstituiranih indena i spiroindena / Topolovčan, Nikola (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2022

  repozitorij.pmf.unizg.hr

• Petrić, Karlo | Stereoselektivna fotokemijska dearomatizacija elektronima bogatih arena / Topolovčan, Nikola (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2022

  repozitorij.pmf.unizg.hr

• Duplić, Filip | Utjecaj veličine supstituenta na stereoselektivnost priprave derivata 3-metilenizoindolinona / Gredičak, Matija (mentor); Topolovčan, Nikola (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2022

  repozitorij.pmf.unizg.hrzir.nsk.hr