Dr. Saša Kazazić
Bijenička 54
HR-10000 Zagreb
Education
- 1995 B.Sc. (Chemistry), Faculty of Science, University of Zagreb
- 1999 M.Sc. (Chemistry), Faculty of Science, University of Zagreb
- 2003 Ph.D. (Chemistry), Faculty of Science, University of Zagreb
Publications
Journal articles
Scientific and review papers
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Ban, Ž., Barišić, A., Crnolatac, I., Kazazić, S., Škulj, S., Savini, F., Bertoša, B., Barišić, I. & Piantanida, I. (2023) Highly selective preparation of N-terminus Horseradish peroxidase-DNA conjugate with fully retained enzymatic activity: HRP-DNA structure – activity relation. Enzyme and microbial technology, 168, 110257, 11 doi:10.1016/j.enzmictec.2023.110257.
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Habinovec, I., Mikulandra, I., Pranjić, P., Kazazić, S., Čipčić Paljetak, H., Bertoša, B., Barišić, A., Bukvić, M. & Novak, P. (2022) Screening of novel antimicrobial diastereomers of azithromycin-thiosemicarbazone conjugates: A combined LC-SPE/cryo NMR, LC-MS/MS and molecular modelling approach,. Antibiotics, 11 (12), 1738, 15 doi:10.3390/antibiotics11121738.
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Banić, M., Butorac, K., Čuljak, N., Leboš Pavunc, A., Novak, J., Bellich, B., Kazazić, S., Kazazić, S., Cescutti, P., Šušković, J., Zucko, J. & Kos, B. (2022) The Human Milk Microbiota Produces Potential Therapeutic Biomolecules and Shapes the Intestinal Microbiota of Infants. International journal of molecular sciences, 23, 14382, 22 doi:10.3390/ijms232214382.
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Šarić, E., Quinn, G., Nalpas, N., Paradžik, T., Kazazić, S., Filić, Ž., Šemanjski, M., Herron, P., Hunter, I., Maček, B. & Vujaklija, D. (2022) Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production. mSystems, 7 (5), 1-20 doi:10.1128/msystems.00199-22.
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Kurtović, T., Ravlić, S., Štimac, A., Mateljak Lukačević, S., Hećimović, A., Kazazić, S. & Halassy, B. (2022) Efficient and Sustainable Platform for Preparation of a High-Quality Immunoglobulin G as an Urgent Treatment Option During Emerging Virus Outbreaks. Frontiers in Immunology, 13, 889736, 11 doi:10.3389/fimmu.2022.889736.
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Wojtyś, M., Jaźwiec, R., Kazazić, S., Leščić Ašler, I., Knežević, P., Aleksić Sabo, V., Luić, M., Jagusztyn- Krynicka, E. & Bzowska, A. (2021) A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori. Applied microbiology and biotechnology, 105, 7949-7967 doi:10.1007/s00253-021-11510-9.
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Habinovec, I., Mikulandra, I., Sekula, L., Gašperov, J., Kazazić, S. & Novak, P. (2021) Rapid Structure Determination of Bioactive 4''-tetrahydrofurfuryl Macrozone Reaction Mixture Components by LC/SPE/Cryo NMR and MS. Molecules, 26 (6316), 26206316, 11 doi:10.3390/molecules26206316.
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Matić, S., Kekez, I., Tomin, M., Bogár, F., Šupljika, F., Kazazić, S., Hanić, M., Jha, S., Brkić, H., Bourgeois, B., Madl, T., Gruber, K., Macheroux, P., Matković-Čalogović, D., Matovina, M. & Tomić, S. (2021) Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process. Journal of biomolecular structure & dynamics, 39 (18), 6870-6881 doi:10.1080/07391102.2020.1804455.
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Ljubić, I., Cvitaš, M., Grazioli, C., Coreno, M., Kazazić, S. & Novak, I. (2020) Vibrationally resolved valence and core photoionization and photoexcitation spectra of an electron-deficient trivalent boron compound: the case of catecholborane. PCCP. Physical chemistry chemical physics, 22, 25396-25407 doi:10.1039/D0CP04822D.
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Benković, T., Kontrec, D., Kazazić, S., Chiş, V., Miljanić, S. & Galić, N. (2020) Diverse coordination of aroylhydrazones toward iron(III) in solid state and in solution: spectrometric, spectroscopic and computational study. Molecular diversity, 24, 1253-1263 doi:10.1007/s11030-019-09989-6.
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Medić, A., Stojanović, K., Izrael- Živković, L., Beškoski, V., Lončarević, B., Kazazić, S. & Karadžić, I. (2019) A comprehensive study of conditions of the biodegradation of a plastic additive 2,6-di-tert-butylphenol and proteomic changes in the degrader Pseudomonas aeruginosa san ai. RSC Advances, 9 (41), 23696-23710 doi:10.1039/c9ra04298a.
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Babić, D., Kazazić, S. & Smith, D. (2019) Resolution of protein hydrogen/deuterium exchange by fitting amide exchange probabilities to the peptide isotopic envelopes. RCM. Rapid communications in mass spectrometry, 33 (15), 1248-1257 doi:10.1002/rcm.8460.
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Tranfić Bakić, M., Klarić, D., Espinosa, M., Kazazić, S., Frkanec, L., Babay, P. & Galić, N. (2019) Syntheses of ester and amide derivatives of calix[6]arene and their complexation affinities towards La3+, Eu3+, and Yb3+. Supramolecular chemistry, 31, GSCH 1650179, 20 doi:10.1080/10610278.2019.1650179.
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Agić, D., Brkić, H., Kazazić, S., Tomić, A. & Abramić, M. (2019) Aprotinin interacts with substrate-binding site of human dipeptidyl peptidase III. Journal of Biomolecular Structure and Dynamics, 37 (14), 3596-3606 doi:10.1080/07391102.2018.1521343.
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Izrael-Živković, L., Rikalović, M., Gojgić-Cvijović, G., Kazazić, S., Vrvić, M., Brčeski, I., Beškoski, V., Lončarević, B., Gopčević, K. & Karadžić, I. (2018) Cadmium specific proteomic responses of a highly resistant Pseudomonas aeruginosa san ai. RSC Advances, 8 (19), 10549-10560 doi:10.1039/c8ra00371h.
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Bartkiewicz, M., Kazazić, S., Krasowska, J., Clark, P., Wielgus-Kutrowska, B. & Bzowska, A. (2018) Non-fluorescent mutant of green fluorescent protein sheds light on the mechanism of chromophore formation. FEBS letters, 592 (9), 1516-1523 doi:10.1002/1873-3468.13051.
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Štefanić, Z., Narczyk, M., Mikleušević, G., Kazazić, S., Bzowska, A. & Luić, M. (2018) Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Scientific Reports, 8, 15427, 13 doi:10.1038/s41598-018-33723-1.
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Kazazić, S., Karačić, Z., Sabljić, I., Agić, D., Tomin, M., Abramić, M., Dadlez, M., Tomić, A. & Tomić, S. (2018) Conservation of the conformational dynamics and ligand binding within M49 enzyme family. RSC Advances, 8 (24), 13310-13322 doi:10.1039/c7ra13059g.
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Banić, M., Uroić, K., Leboš Pavunc, A., Novak, J., Zorić, K., Durgo, K., Petković, H., Jamnik, P., Kazazić, S., Kazazić, S., Radović, S., Scalabrin, S., Hynӧnen, U., Šušković, J. & Kos, B. (2018) Characterization of S-layer proteins of potential probiotic starter culture Lactobacillus brevis SF9B isolated from sauerkraut. LWT-Food Science and Technology, 93, 257-267 doi:10.1016/j.lwt.2018.03.054.
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Gašparović, B., Penezić, A., Frka, S., Kazazić, S., Lampitt, R., Holhuin, F., Sudasinghe, N. & Schaub, T. (2018) Particulate sulfur-containing lipids: production and cycling from the epipelagic to the abyssopelagic zone. Deep-sea research. Part 1. Oceanographic research papers, 134 (1), 12-22 doi:10.1016/j.dsr.2018.03.007.
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Ljubić, I., Kivimäki, A., Coreno, M., Kazazić, S. & Novak, I. (2018) Characterisation of the electronic structure of galvinoxyl free radical by variable energy UPS, XPS and NEXAFS spectroscopy. PCCP. Physical chemistry chemical physics, 20 (4), 2480-2491 doi:10.1039/C7CP07266J.
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Hromić-Jahjefendić, A., Jajčanin Jozić, N., Kazazić, S., Grabar Branilović, M., Karačić, Z., Schrittwieser, J., Das, K., Tomin, M., Oberer, M., Gruber, K., Abramić, M. & Tomić, S. (2017) A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain. PLoS One, 12 (11), e0188915, 27 doi:10.1371/journal.pone.0188915.
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Čadež, V., Škapin, S., Leonardi, A., Križaj, I., Kazazić, S., Salopek-Sondi, B. & Sondi, I. (2017) Formation and morphogenesis of a cuttlebone's aragonite biomineral structures for the common cuttlefish (Sepia officinalis) on the nanoscale : Revisited. Journal of colloid and interface science, 508, 95-104 doi:10.1016/j.jcis.2017.08.028.
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Gundić, M., Tomić, A., Wade, R., Matovina, M., Karačić, Z., Kazazić, S. & Tomić, S. (2016) Human DPP III – Keap1 Interactions : A Combined Experimental And Computational study. Croatica chemica acta, 89 (2), 217-228 doi:10.5562/cca2916.
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Kazazić, S., Bertoša, B., Luić, M., Mikleušević, G., Tarnowski, K., Dadlez, M., Narczyk, M. & Bzowska, A. (2016) New insights into active site conformation dynamics of E. coli PNP revealed by combined H/D exchange approach and molecular dynamics simulations. Journal of the American Society for Mass Spectrometry, 27 (1), 73-82 doi:10.1007/s13361-015-1239-2.
doi Babić, D., Kazazić, S. & Smith, D. (2013) Kinetics of H/D Exchange by Mass Spectrometry. I. Analysis of a Single Exchange Profile. MATCH : communications in mathematical and in computer chemistry, 70 (3), 801-827. (https://www.bib.irb.hr/654177).
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Klasinc, L., Srzić, D., Kazazić, S. & Rožman, M. (2010) 50 Years of Mass Spectrometry at Ruđer Bošković Institute. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 59 (12), 591-597.
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Kazazić, S., Zhang, H., Schaub, T., Emmett, M., Hendrickson, C., Blakney, G. & Marshall, A. (2010) Automated data reduction for hydrogen/deuterium exchange experiments, enabled by high-resolution Fourier transform ion cyclotron resonance mass spectrometry. Journal of the American Society for Mass Spectrometry, 21 (4), 550-558 doi:10.1016/j.jasms.2009.12.016.
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Turčić, P., Bradamante, M., Houra, K., Štambuk, N., Kelava, T., Konjevoda, P., Kazazić, S., Vikić-Topić, D. & Pokrić, B. (2009) Effects of α-Melanocortin Enantiomers on Acetaminophen-Induced Hepatotoxicity in CBA Mice. Molecules, 14 (12), 5017-5026 doi:10.3390/molecules14125017.
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Kazazić, S., Kazazić, S. & Srzić, D. (2009) Gas-phase Ligation of Cr+/Fe+/Ni+ Ions with Iodine. Croatica chemica acta, 82 (4), 841-843.
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Zhang, H., Kazazić, S., Schaub, T., Tipton, J., Emmett, M. & Marshall, A. (2008) Enhanced Digestion Efficiency, Peptide Ionization Efficiency, and Sequence Resolution for Protein Hydrogen/Deuterium Exchange Monitored by FT-ICR Mass Spectrometry. Analytical chemistry, 80 (23), 9034-9041 doi:10.1021/ac801417d.
doi Emmett, M., Kazazić, S., Marshall, A., Chen, W., Shi, S., Bolanos, B. & Greig, M. (2006) Hydrogen/deuterium back exchange in solution-phase hydrogen/deuterium exchange with mass spectrometric analysis. Analytical Chemistry, 78 (19), 7058-7060.
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Kazazić, S., Kazazić, S., Klasinc, L., Rožman, M. & Srzić, D. (2006) Gas phase ligation of U+. Comparison of pyrene, phenanthridine and phenanthrene as ligands. Croatica chemica acta, 79 (1), 125-128.
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Kazazić, S., Kazazić, S., Klasinc, L., Rožman, M. & Srzić, D. (2005) Gas phase ligation kinetics of metal monocations with pyrene. Croatica chemica acta, 78 (2), 269-274.
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Kazazić, S., Kazazić, S., Klasinc, L., McGlynn, S. & Srzić, D. (2004) Gas-phase reactions of Nb+ and Fe+ with perfluoronaphthalene and perfluoroanthracene. RCM. Rapid communications in mass spectrometry, 18 (19), 2354-2356 doi:10.1002/rcm.1616.
doi Kazazić, S., Klasinc, L., McGlynn, S., Srzić, D. & Vicente, M. (2004) Gas-phase metallation reactions of porphyrins with metal monocations. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 108 (50), 10997-11000.
Kazazić, S. & Martinović, S. (2004) Chemical ionization mass spectrometry. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 53 (6), 265-272.
Kazazić, S., Klasinc, L., Rožman, M., Srzić, D. & von Knop, J. (2004) Isotope effect in the gas phase reaction of pyrene-D10 with Nb+ ions. Croatica chemica acta, 77 (1-2), 321-324.
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Rožman, M., Kazazić, S., Klasinc, L. & Srzić, D. (2003) Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan. RCM. Rapid communications in mass spectrometry, 17 (24), 2769-2772 doi:10.1002/rcm.1261.
doi Srzić, D., Kazazić, S., Kralj, B., Klasinc, L., Marsel, J., Güsten, H. & McGlynn, S. (2003) The niobium and tantalum riddle: gas-phase monocation reactions with pyrene and pyrene-D10. International Journal of Mass Spectrometry, 230 (2-3), 135-140.
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Kazazić, S., Klasinc, L., Kovač, B. & Srzić, D. (2003) Gas phase ligation of Cr+ and Fe+ with 4, 9-diazapyrene. RCM. Rapid communications in mass spectrometry, 17 (20), 2361-2363 doi:10.1002/rcm.1204.
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Kazazić, S., Kazazić, P., Klasinc, L., McGlynn, S. & Pryor, W. (2002) Proton affinities of N-O anions and their protonated forms. Journal of Physical Organic Chemistry, 15 (10), 728-731 doi:10.1002/poc.536.
doi Cvitaš, T., Kazazić, S., Kazazić, S., Kezele, N., Klasinc, L., Srzić, D. & Budzikiewicz, H. (2001) Gas phase kinetics of metal ion ligation by pyrene. Croatica Chemica Acta, 74 (3), 725-733.
Kazazić, S., Kazazić, S., Klasinc, L., McGlynn, S. & Pryor, W. (2001) On the proton affinity of peroxynitrite and peroxynitrous acid. Croatica Chemica Acta, 74 (2), 271-275.
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Eckert-Maksić, M., Kazazić, S., Kazazić, S., Kirin, S., Klasinc, L., Srzić, D. & Žigon, D. (2001) Electron ionisation induced fragmentation of fused norbornene analogues containing SiMe2 or GeMe2 and oxygen bridges. Migration of SiMe2 and GeMe2 groups. RCM. Rapid communications in mass spectrometry, 15 (7), 462-465 doi:10.1002/rcm.256.
doi Srzić, D., Kazazić, S., Martinović, S., Paša-Tolić, L., Kezele, N., Vikić-Topić, D., Pečur, S., Vrančić, A. & Klasinc, L. (2000) FTMS of natural polymers. Croatica Chemica Acta, 73 (1), 69-80.
Rožman, M. & Kazazić, S. (2000) LDI/FTMS study of the H/D exchange of gramicidin S with D2S. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 49 (1), 1-5.
Friedman, M., Kazazić, S., Kezele, N., Klasinc, L., McGlynn, S., Pečur, S. & Pryor, W. (2000) Role of nitrogen oxides in ozone toxicity. Croatica chemica acta, 73, 1141-1151.
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Budzikiewicz, H., Cvitaš, T., Kazazić, S., Klasinc, L. & Srzić, D. (1999) Gas phase reaction rate measurements in Fourier transform mass spectrometry. RCM. Rapid communications in mass spectrometry, 13 (12), 1109-1111 doi:10.1002/(SICI)1097-0231(19990630)13:123.0.CO ; 2-N.
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Srzić, D., Kazazić, S., Klasinc, L. & Budzikiewicz, H. (1997) Gas-phase Synthesis and Reactions of Complexes of Polycyclic Aromatics with Metallic Positive Ions. RCM. Rapid communications in mass spectrometry, 11 (10), 1131-1133 doi:10.1002/(SICI)1097-0231(19970630)11:103.0.CO ; 2-D.
doi Srzić, D., Kazazić, S., Klasinc, L., Güsten, H. & McGlynn, S. (1997) An FTMS Investigation of the Competition between Uranium Oxidation and Ligation Reactions. Croatica chemica acta, 70 (1), 223-228.
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Mlinarić-Majerski, K., Kazazić, S., Vinković, M. & Kragol, G. (1996) Solvent and temperature effects in Pi-route cyclization. Croatica chemica acta, 69 (4), 1339-1345.
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Srzić, D., Kazazić, S. & Klasinc, L. (1996) Deuterium labeling study of the gas-phase reaction of Fe^+/Cr^+ with Pyrene by FTMS. Croatica chemica acta, 69 (4), 1449-1454.
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Srzić, D., Kazazić, S. & Klasinc, L. (1996) Gas-phase Reaction of Iron Fe+ Ions with Phenanthrene and 9-Azaphenanthrene in a Laser Desorption/Ionization Fourier-transform Mass Spectrometry Experiment. RCM. Rapid communications in mass spectrometry, 10 (6), 688-690 doi:10.1002/(SICI)1097-0231(199604)10:63.0.CO ; 2-D.
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Srzić, D., Martinović, S., Paša-Tolić, L., Kezele, N., Kazazić, S., Senković, L., Shevchenko, S. & Klasinc, L. (1996) Laser Desorption Fourier Transform Mass Spectrometry of Natural Polymers. RCM. Rapid communications in mass spectrometry, 10 (5), 580-582 doi:10.1002/(SICI)1097-0231(19960331)10:53.0.CO ; 2-8.
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Theses
Doctoral dissertation
Kazazić, S. (2003) 'Formation of singly charged metal complexes in the gas phase', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.
Master thesis
Kazazić, S. (1999) 'ICR FTMS Investigation of the Reactions of Metal Ions with Pyrene', magistarski rad, Prirodoslovno-matematički fakultet, Zagreb.
Membership in professional associations / societies
Croatian Chemical Society
American Society for Mass Spectrometry