Dr. Saša Kazazić
Bijenička 54
HR-10000 Zagreb
Education
- 1995 B.Sc. (Chemistry), Faculty of Science, University of Zagreb
- 1999 M.Sc. (Chemistry), Faculty of Science, University of Zagreb
- 2003 Ph.D. (Chemistry), Faculty of Science, University of Zagreb
Publications
Journal articles
Scientific and review papers
Habinovec, I., Mikulandra, I., Pranjić, P., Kazazić, S., Čipčić Paljetak, H., Bertoša, B., Barišić, A., Bukvić, M. & Novak, P. (2022) Screening of novel antimicrobial diastereomers of azithromycin-thiosemicarbazone conjugates: A combined LC-SPE/cryo NMR, LC-MS/MS and molecular modelling approach,. Antibiotics, 11 (12), 1738, 15. (https://www.bib.irb.hr/1241662).
-
Banić, M., Butorac, K., Čuljak, N., Leboš Pavunc, A., Novak, J., Bellich, B., Kazazić, S., Kazazić, S., Cescutti, P., Šušković, J., Zucko, J. & Kos, B. (2022) The Human Milk Microbiota Produces Potential Therapeutic Biomolecules and Shapes the Intestinal Microbiota of Infants. International journal of molecular sciences, 23, 14382, 22 doi:10.3390/ijms232214382.
doiwww.mdpi.comfulir.irb.hr -
Šarić, E., Quinn, G., Nalpas, N., Paradžik, T., Kazazić, S., Filić, Ž., Šemanjski, M., Herron, P., Hunter, I., Maček, B. & Vujaklija, D. (2022) Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production. mSystems, 7 (5), 1-20 doi:10.1128/msystems.00199-22.
doijournals.asm.orgfulir.irb.hr -
Kurtović, T., Ravlić, S., Štimac, A., Mateljak Lukačević, S., Hećimović, A., Kazazić, S. & Halassy, B. (2022) Efficient and Sustainable Platform for Preparation of a High-Quality Immunoglobulin G as an Urgent Treatment Option During Emerging Virus Outbreaks. Frontiers in Immunology, 13, 889736, 11 doi:10.3389/fimmu.2022.889736.
doiwww.frontiersin.org -
Wojtyś, M., Jaźwiec, R., Kazazić, S., Leščić Ašler, I., Knežević, P., Aleksić Sabo, V., Luić, M., Jagusztyn- Krynicka, E. & Bzowska, A. (2021) A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori. Applied microbiology and biotechnology, 105, 7949-7967 doi:10.1007/s00253-021-11510-9.
doilink.springer.comdoi.orgfulir.irb.hr -
Habinovec, I., Mikulandra, I., Sekula, L., Gašperov, J., Kazazić, S. & Novak, P. (2021) Rapid Structure Determination of Bioactive 4''-tetrahydrofurfuryl Macrozone Reaction Mixture Components by LC/SPE/Cryo NMR and MS. Molecules, 26 (6316), 26206316, 11 doi:10.3390/molecules26206316.
doiwww.mdpi.comwww.mdpi.comdoi.orgfulir.irb.hr -
Matić, S., Kekez, I., Tomin, M., Bogár, F., Šupljika, F., Kazazić, S., Hanić, M., Jha, S., Brkić, H., Bourgeois, B., Madl, T., Gruber, K., Macheroux, P., Matković-Čalogović, D., Matovina, M. & Tomić, S. (2021) Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process. Journal of biomolecular structure & dynamics, 39 (18), 6870-6881 doi:10.1080/07391102.2020.1804455.
doi -
Ljubić, I., Cvitaš, M., Grazioli, C., Coreno, M., Kazazić, S. & Novak, I. (2020) Vibrationally resolved valence and core photoionization and photoexcitation spectra of an electron-deficient trivalent boron compound: the case of catecholborane. PCCP. Physical chemistry chemical physics, 22, 25396-25407 doi:10.1039/D0CP04822D.
doi -
Benković, T., Kontrec, D., Kazazić, S., Chiş, V., Miljanić, S. & Galić, N. (2020) Diverse coordination of aroylhydrazones toward iron(III) in solid state and in solution: spectrometric, spectroscopic and computational study. Molecular diversity, 24, 1253-1263 doi:10.1007/s11030-019-09989-6.
doi -
Medić, A., Stojanović, K., Izrael- Živković, L., Beškoski, V., Lončarević, B., Kazazić, S. & Karadžić, I. (2019) A comprehensive study of conditions of the biodegradation of a plastic additive 2,6-di-tert-butylphenol and proteomic changes in the degrader Pseudomonas aeruginosa san ai. RSC Advances, 9 (41), 23696-23710 doi:10.1039/c9ra04298a.
doi -
Babić, D., Kazazić, S. & Smith, D. (2019) Resolution of protein hydrogen/deuterium exchange by fitting amide exchange probabilities to the peptide isotopic envelopes. RCM. Rapid communications in mass spectrometry, 33 (15), 1248-1257 doi:10.1002/rcm.8460.
doi -
Tranfić Bakić, M., Klarić, D., Espinosa, M., Kazazić, S., Frkanec, L., Babay, P. & Galić, N. (2019) Syntheses of ester and amide derivatives of calix[6]arene and their complexation affinities towards La3+, Eu3+, and Yb3+. Supramolecular chemistry, 31, GSCH 1650179, 20 doi:10.1080/10610278.2019.1650179.
doi -
Agić, D., Brkić, H., Kazazić, S., Tomić, A. & Abramić, M. (2019) Aprotinin interacts with substrate-binding site of human dipeptidyl peptidase III. Journal of Biomolecular Structure and Dynamics, 37 (14), 3596-3606 doi:10.1080/07391102.2018.1521343.
doifulir.irb.hrdoi.orgwww.tandfonline.com -
Izrael-Živković, L., Rikalović, M., Gojgić-Cvijović, G., Kazazić, S., Vrvić, M., Brčeski, I., Beškoski, V., Lončarević, B., Gopčević, K. & Karadžić, I. (2018) Cadmium specific proteomic responses of a highly resistant Pseudomonas aeruginosa san ai. RSC Advances, 8 (19), 10549-10560 doi:10.1039/c8ra00371h.
doi -
Bartkiewicz, M., Kazazić, S., Krasowska, J., Clark, P., Wielgus-Kutrowska, B. & Bzowska, A. (2018) Non-fluorescent mutant of green fluorescent protein sheds light on the mechanism of chromophore formation. FEBS letters, 592 (9), 1516-1523 doi:10.1002/1873-3468.13051.
doi -
Štefanić, Z., Narczyk, M., Mikleušević, G., Kazazić, S., Bzowska, A. & Luić, M. (2018) Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Scientific Reports, 8, 15427, 13 doi:10.1038/s41598-018-33723-1.
doiwww.nature.comfulir.irb.hr -
Kazazić, S., Karačić, Z., Sabljić, I., Agić, D., Tomin, M., Abramić, M., Dadlez, M., Tomić, A. & Tomić, S. (2018) Conservation of the conformational dynamics and ligand binding within M49 enzyme family. RSC Advances, 8 (24), 13310-13322 doi:10.1039/c7ra13059g.
doipubs.rsc.orgpubs.rsc.orgfulir.irb.hr -
Banić, M., Uroić, K., Leboš Pavunc, A., Novak, J., Zorić, K., Durgo, K., Petković, H., Jamnik, P., Kazazić, S., Kazazić, S., Radović, S., Scalabrin, S., Hynӧnen, U., Šušković, J. & Kos, B. (2018) Characterization of S-layer proteins of potential probiotic starter culture Lactobacillus brevis SF9B isolated from sauerkraut. LWT-Food Science and Technology, 93, 257-267 doi:10.1016/j.lwt.2018.03.054.
doi -
Gašparović, B., Penezić, A., Frka, S., Kazazić, S., Lampitt, R., Holhuin, F., Sudasinghe, N. & Schaub, T. (2018) Particulate sulfur-containing lipids: production and cycling from the epipelagic to the abyssopelagic zone. Deep-sea research. Part 1. Oceanographic research papers, 134 (1), 12-22 doi:10.1016/j.dsr.2018.03.007.
doi -
Ljubić, I., Kivimäki, A., Coreno, M., Kazazić, S. & Novak, I. (2018) Characterisation of the electronic structure of galvinoxyl free radical by variable energy UPS, XPS and NEXAFS spectroscopy. PCCP. Physical chemistry chemical physics, 20 (4), 2480-2491 doi:10.1039/C7CP07266J.
doi -
Hromić-Jahjefendić, A., Jajčanin Jozić, N., Kazazić, S., Grabar Branilović, M., Karačić, Z., Schrittwieser, J., Das, K., Tomin, M., Oberer, M., Gruber, K., Abramić, M. & Tomić, S. (2017) A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain. PLoS One, 12 (11), e0188915, 27 doi:10.1371/journal.pone.0188915.
doifulir.irb.hr -
Čadež, V., Škapin, S., Leonardi, A., Križaj, I., Kazazić, S., Salopek-Sondi, B. & Sondi, I. (2017) Formation and morphogenesis of a cuttlebone's aragonite biomineral structures for the common cuttlefish (Sepia officinalis) on the nanoscale : Revisited. Journal of colloid and interface science, 508, 95-104 doi:10.1016/j.jcis.2017.08.028.
doi -
Gundić, M., Tomić, A., Wade, R., Matovina, M., Karačić, Z., Kazazić, S. & Tomić, S. (2016) Human DPP III – Keap1 Interactions : A Combined Experimental And Computational study. Croatica chemica acta, 89 (2), 217-228 doi:10.5562/cca2916.
doihrcak.srce.hr -
Kazazić, S., Bertoša, B., Luić, M., Mikleušević, G., Tarnowski, K., Dadlez, M., Narczyk, M. & Bzowska, A. (2016) New insights into active site conformation dynamics of E. coli PNP revealed by combined H/D exchange approach and molecular dynamics simulations. Journal of the American Society for Mass Spectrometry, 27 (1), 73-82 doi:10.1007/s13361-015-1239-2.
doi Babić, D., Kazazić, S. & Smith, D. (2013) Kinetics of H/D Exchange by Mass Spectrometry. I. Analysis of a Single Exchange Profile. MATCH : communications in mathematical and in computer chemistry, 70 (3), 801-827. (https://www.bib.irb.hr/654177).
-
Klasinc, L., Srzić, D., Kazazić, S. & Rožman, M. (2010) 50 Years of Mass Spectrometry at Ruđer Bošković Institute. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 59 (12), 591-597.
hrcak.srce.hrfulir.irb.hr -
Kazazić, S., Zhang, H., Schaub, T., Emmett, M., Hendrickson, C., Blakney, G. & Marshall, A. (2010) Automated data reduction for hydrogen/deuterium exchange experiments, enabled by high-resolution Fourier transform ion cyclotron resonance mass spectrometry. Journal of the American Society for Mass Spectrometry, 21 (4), 550-558 doi:10.1016/j.jasms.2009.12.016.
doi -
Turčić, P., Bradamante, M., Houra, K., Štambuk, N., Kelava, T., Konjevoda, P., Kazazić, S., Vikić-Topić, D. & Pokrić, B. (2009) Effects of α-Melanocortin Enantiomers on Acetaminophen-Induced Hepatotoxicity in CBA Mice. Molecules, 14 (12), 5017-5026 doi:10.3390/molecules14125017.
doidoi.orgfulir.irb.hr -
Kazazić, S., Kazazić, S. & Srzić, D. (2009) Gas-phase Ligation of Cr+/Fe+/Ni+ Ions with Iodine. Croatica chemica acta, 82 (4), 841-843.
hrcak.srce.hr -
Zhang, H., Kazazić, S., Schaub, T., Tipton, J., Emmett, M. & Marshall, A. (2008) Enhanced Digestion Efficiency, Peptide Ionization Efficiency, and Sequence Resolution for Protein Hydrogen/Deuterium Exchange Monitored by FT-ICR Mass Spectrometry. Analytical chemistry, 80 (23), 9034-9041 doi:10.1021/ac801417d.
doi Emmett, M., Kazazić, S., Marshall, A., Chen, W., Shi, S., Bolanos, B. & Greig, M. (2006) Hydrogen/deuterium back exchange in solution-phase hydrogen/deuterium exchange with mass spectrometric analysis. Analytical Chemistry, 78 (19), 7058-7060.
-
Kazazić, S., Kazazić, S., Klasinc, L., Rožman, M. & Srzić, D. (2006) Gas phase ligation of U+. Comparison of pyrene, phenanthridine and phenanthrene as ligands. Croatica chemica acta, 79 (1), 125-128.
hrcak.srce.hr -
Kazazić, S., Kazazić, S., Klasinc, L., Rožman, M. & Srzić, D. (2005) Gas phase ligation kinetics of metal monocations with pyrene. Croatica chemica acta, 78 (2), 269-274.
hrcak.srce.hr -
Kazazić, S., Kazazić, S., Klasinc, L., McGlynn, S. & Srzić, D. (2004) Gas-phase reactions of Nb+ and Fe+ with perfluoronaphthalene and perfluoroanthracene. RCM. Rapid communications in mass spectrometry, 18 (19), 2354-2356 doi:10.1002/rcm.1616.
doi Kazazić, S., Klasinc, L., McGlynn, S., Srzić, D. & Vicente, M. (2004) Gas-phase metallation reactions of porphyrins with metal monocations. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 108 (50), 10997-11000.
Kazazić, S. & Martinović, S. (2004) Chemical ionization mass spectrometry. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 53 (6), 265-272.
Kazazić, S., Klasinc, L., Rožman, M., Srzić, D. & von Knop, J. (2004) Isotope effect in the gas phase reaction of pyrene-D10 with Nb+ ions. Croatica chemica acta, 77 (1-2), 321-324.
-
Rožman, M., Kazazić, S., Klasinc, L. & Srzić, D. (2003) Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan. RCM. Rapid communications in mass spectrometry, 17 (24), 2769-2772 doi:10.1002/rcm.1261.
doi Srzić, D., Kazazić, S., Kralj, B., Klasinc, L., Marsel, J., Güsten, H. & McGlynn, S. (2003) The niobium and tantalum riddle: gas-phase monocation reactions with pyrene and pyrene-D10. International Journal of Mass Spectrometry, 230 (2-3), 135-140.
-
Kazazić, S., Klasinc, L., Kovač, B. & Srzić, D. (2003) Gas phase ligation of Cr+ and Fe+ with 4, 9-diazapyrene. RCM. Rapid communications in mass spectrometry, 17 (20), 2361-2363 doi:10.1002/rcm.1204.
doi -
Kazazić, S., Kazazić, P., Klasinc, L., McGlynn, S. & Pryor, W. (2002) Proton affinities of N-O anions and their protonated forms. Journal of Physical Organic Chemistry, 15 (10), 728-731 doi:10.1002/poc.536.
doi Cvitaš, T., Kazazić, S., Kazazić, S., Kezele, N., Klasinc, L., Srzić, D. & Budzikiewicz, H. (2001) Gas phase kinetics of metal ion ligation by pyrene. Croatica Chemica Acta, 74 (3), 725-733.
Kazazić, S., Kazazić, S., Klasinc, L., McGlynn, S. & Pryor, W. (2001) On the proton affinity of peroxynitrite and peroxynitrous acid. Croatica Chemica Acta, 74 (2), 271-275.
-
Eckert-Maksić, M., Kazazić, S., Kazazić, S., Kirin, S., Klasinc, L., Srzić, D. & Žigon, D. (2001) Electron ionisation induced fragmentation of fused norbornene analogues containing SiMe2 or GeMe2 and oxygen bridges. Migration of SiMe2 and GeMe2 groups. RCM. Rapid communications in mass spectrometry, 15 (7), 462-465 doi:10.1002/rcm.256.
doi Srzić, D., Kazazić, S., Martinović, S., Paša-Tolić, L., Kezele, N., Vikić-Topić, D., Pečur, S., Vrančić, A. & Klasinc, L. (2000) FTMS of natural polymers. Croatica Chemica Acta, 73 (1), 69-80.
Rožman, M. & Kazazić, S. (2000) LDI/FTMS study of the H/D exchange of gramicidin S with D2S. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 49 (1), 1-5.
Friedman, M., Kazazić, S., Kezele, N., Klasinc, L., McGlynn, S., Pečur, S. & Pryor, W. (2000) Role of nitrogen oxides in ozone toxicity. Croatica chemica acta, 73, 1141-1151.
-
Budzikiewicz, H., Cvitaš, T., Kazazić, S., Klasinc, L. & Srzić, D. (1999) Gas phase reaction rate measurements in Fourier transform mass spectrometry. RCM. Rapid communications in mass spectrometry, 13 (12), 1109-1111 doi:10.1002/(SICI)1097-0231(19990630)13:123.0.CO ; 2-N.
doi -
Srzić, D., Kazazić, S., Klasinc, L. & Budzikiewicz, H. (1997) Gas-phase Synthesis and Reactions of Complexes of Polycyclic Aromatics with Metallic Positive Ions. RCM. Rapid communications in mass spectrometry, 11 (10), 1131-1133 doi:10.1002/(SICI)1097-0231(19970630)11:103.0.CO ; 2-D.
doi Srzić, D., Kazazić, S., Klasinc, L., Güsten, H. & McGlynn, S. (1997) An FTMS Investigation of the Competition between Uranium Oxidation and Ligation Reactions. Croatica chemica acta, 70 (1), 223-228.
-
Mlinarić-Majerski, K., Kazazić, S., Vinković, M. & Kragol, G. (1996) Solvent and temperature effects in Pi-route cyclization. Croatica chemica acta, 69 (4), 1339-1345.
hrcak.srce.hr -
Srzić, D., Kazazić, S. & Klasinc, L. (1996) Deuterium labeling study of the gas-phase reaction of Fe^+/Cr^+ with Pyrene by FTMS. Croatica chemica acta, 69 (4), 1449-1454.
hrcak.srce.hr -
Srzić, D., Kazazić, S. & Klasinc, L. (1996) Gas-phase Reaction of Iron Fe+ Ions with Phenanthrene and 9-Azaphenanthrene in a Laser Desorption/Ionization Fourier-transform Mass Spectrometry Experiment. RCM. Rapid communications in mass spectrometry, 10 (6), 688-690 doi:10.1002/(SICI)1097-0231(199604)10:63.0.CO ; 2-D.
doi -
Srzić, D., Martinović, S., Paša-Tolić, L., Kezele, N., Kazazić, S., Senković, L., Shevchenko, S. & Klasinc, L. (1996) Laser Desorption Fourier Transform Mass Spectrometry of Natural Polymers. RCM. Rapid communications in mass spectrometry, 10 (5), 580-582 doi:10.1002/(SICI)1097-0231(19960331)10:53.0.CO ; 2-8.
doi
Theses
Doctoral dissertation
Kazazić, S. (2003) 'Formation of singly charged metal complexes in the gas phase', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.
Master thesis
Kazazić, S. (1999) 'ICR FTMS Investigation of the Reactions of Metal Ions with Pyrene', magistarski rad, Prirodoslovno-matematički fakultet, Zagreb.
Membership in professional associations / societies
Croatian Chemical Society
American Society for Mass Spectrometry