Dr. Tana Tandarić
Ruđer Bošković Institute
Bijenička 54
HR-10000 Zagreb
Education
Faculty of Science, University of Zagreb 2016 - 2021
- PhD in chemistry, Chemistry department
- Doctoral thesis: "Computational investigation of the mechanism of the irreversibleinhibition of the monoamine oxidase B enzyme", thesis supervisor Dr. Robert Vianello
Faculty of Pharmacy and Biochemistry, University of Zagreb 2011 - 2016
- Master od medicinal chemistry
- Master thesis: "Mechanism of chlorination reaction between 5-fluorouracil." thesis supervisor Dr. Valerije Vrček
- Student practice at Department of Medicinal Chemistry, University Hospital for Tumors, Zagreb (Croatia)
XV. gymnasium Zagreb 2007.-2011.
Elemetary school OŠ Murterski škoji Murter 1999.-2007.
Awards and Achievements
- 2021: Scholarship of the Austrian Academy of Arts and Sciences (JESH - Croatia) for a stay of six months in Max Perutz labs (Vienna, Austria)
- Annual Ruđer Bošković Institute award for published scientific paper in 2019 and 2020
- 09/2019: Thiene poster award, 16th European Symposium of Organic Reactivity, Dubrovnik
- 2019: French Government Scholarship for a one-month stay at the Sorbonne University (Paris, France).
- Recipient of the Annual Dean's Award for Scientific Work "Chlorination of N-Methylacetamide and Amide-Containing Pharmaceuticals. Quantum- Chemical Study of the Reaction Mechanism. " published in scientific Journal of Physical Chemistry A for the academic year 2013/2014.
- Recipient of the Annual Dean's Award for Student Research "The chemical fate of antiepileptics neutrophile. In silico research of reaction mechanism with hypochlorous acid ." for the academic year 2014/2015.
Classes
General chemistry with stoichiometry, seminars, Faculty of Pharmacy and Biochemistry, University of Zagreb, 2019/2020.
Publications
Journal articles
Scientific and review papers
-
Matić, J., Tandarić, T., Radić Stojković, M., Šupljika, F., Karačić, Z., Tomašić Paić, A., Horvat, L., Vianello, R. & Tumir, L. (2023) Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme. Beilstein journal of organic chemistry, 19, 550-565 doi:10.3762/bjoc.19.40.
doiwww.beilstein-journals.orgfulir.irb.hr -
Pantalon Juraj, N., Tandarić, T., Tadić, V., Perić, B., Moreth, D., Schatzschneider, U., Brozovic, A., Vianello, R. & Kirin, S. (2022) Tuning the coordination properties of chiral pseudopeptide bis(2-picolyl)amine and iminodiacetamide ligands in Zn(II) and Cu(II) complexes. Dalton transactions, 51 (44), 17008-17021 doi:10.1039/d2dt02895f.
doi -
Poje, G., Pessanha de Carvalho, L., Held, J., Moita, D., Prudêncio, M., Perković, I., Tandarić, T., Vianello, R. & Rajić, Z. (2022) Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents. European journal of medicinal chemistry, 238, 114408, 15 doi:10.1016/j.ejmech.2022.114408.
doi -
Marinović, M., Poje, G., Perković, I., Fontinha, D., Prudêncio, M., Held, J., Pessanha de Carvalho, L., Tandarić, T., Vianello, R. & Rajić, Z. (2021) Further investigation of harmicines as novel antiplasmodial agents: synthesis, structure-activity relationship and insight into the mechanism of action. European journal of medicinal chemistry, 224, 113687, 20 doi:10.1016/j.ejmech.2021.113687.
doi -
Matić, J., Jukić, M., Ismaili, H., Saftić, D., Ban, Ž., Tandarić, T., Vianello, R., Opačak-Bernardi, T., Glavaš-Obrovac, L. & Žinić, B. (2021) 6-Morpholino- and 6-amino-9-sulfonylpurine derivatives. Synthesis, computational analysis, and biological activity. Nucleosides, nucleotides & nucleic acids, 40 (4), 470-503 doi:10.1080/15257770.2021.1896001.
doi -
Marinović, M., Perković, I., Fontinha, D., Prudêncio, M., Held, J., Pessanha de Carvalho, L., Tandarić, T., Vianello, R., Zorc, B. & Rajić, Z. (2020) Novel Harmicines with Improved Potency against Plasmodium. Molecules, 25 (19), 4376, 19 doi:10.3390/molecules25194376.
doiwww.mdpi.comfulir.irb.hr -
Tandarić, T., Prah, A., Stare, J., Mavri, J. & Vianello, R. (2020) Hydride Abstraction as the Rate-Limiting Step of the Irreversible Inhibition of Monoamine Oxidase B by Rasagiline and Selegiline: A Computational Empirical Valence Bond Study. International journal of molecular sciences, 21 (17), 6151, 13 doi:10.3390/ijms21176151.
doifulir.irb.hrwww.mdpi.com -
Rimac, H., Tandarić, T., Vianello, R. & Bojić, M. (2020) Indomethacin increases quercetin affinity for human serum albumin: a combined experimental and computational study and its broader implications. International journal of molecular sciences, 21 (16), 5740, 14 doi:10.3390/ijms21165740.
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Perković, I., Raić-Malić, S., Fontinha, D., Prudêncio, M., Pessanha de Carvalho, L., Held, J., Tandarić, T., Vianello, R., Zorc, B. & Rajić, Z. (2020) Harmicines − harmine and cinnamic acid hybrids as novel antiplasmodial hits. European journal of medicinal chemistry, 187, 111927, 16 doi:10.1016/j.ejmech.2019.111927.
doi -
Tandarić, T., Hok, L. & Vianello, R. (2019) From Hydrogen Peroxide-Responsive Boronated Nucleosides Towards Antisense Therapeutics – A Computational Mechanistic Study. Croatica chemica acta, 92 (2), 287-295 doi:10.5562/cca3592.
doihrcak.srce.hrdoi.orgfulir.irb.hr -
Toma, M., Božičević, L., Lapić, J., Djaković, S., Šakić, D., Tandarić, T., Vianello, R. & Vrček, V. (2019) Transacylation in Ferrocenoyl-Purines. NMR and Computational Study of the Isomerization Mechanism. Journal of organic chemistry, 84 (19), 12471-12480 doi:10.1021/acs.joc.9b01944.
doi -
Tandarić, T. & Vianello, R. (2019) Computational Insight into the Mechanism of the Irreversible Inhibition of Monoamine Oxidase Enzymes by the Antiparkinsonian Propargylamine Inhibitors Rasagiline and Selegiline. ACS Chemical Neuroscience, 10 (8), 3532-3542 doi:10.1021/acschemneuro.9b00147.
doifulir.irb.hr -
Matić, J., Šupljika, F., Tandarić, T., Dukši, M., Piotrowski, P., Vianello, R., Brozović, A., Piantanida, I., Schmuck, C. & Radić Stojković, M. (2019) DNA/RNA recognition controlled by the glycine linker and the guanidine moiety of phenanthridine peptides. International journal of biological macromolecules, 134, 422-434 doi:10.1016/j.ijbiomac.2019.05.063.
doifulir.irb.hr -
Hok, L., Ulm, L., Tandarić, T., Krivohlavek, A., Šakić, D. & Vrček, V. (2018) Chlorination of 5-fluorouracil: Reaction mechanism and ecotoxicity assessment of chlorinated products. Chemosphere, 207 (18), 612-619 doi:10.1016/j.chemosphere.2018.05.140.
doiwww.sciencedirect.com -
Tandarić, T. & Vianello, R. (2018) Design of Exceptionally Strong Organic Superbases Based on Aromatic Pnictogen Oxides: Computational DFT Analysis of the Oxygen Basicity in the Gas Phase and Acetonitrile Solution. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 122 (5), 1464-1471 doi:10.1021/acs.jpca.7b11945.
doi -
Dabić, D., Brkljačić, L., Tandarić, T., Žinić, M., Vianello, R., Frkanec, L. & Kobetić, R. (2018) The Metal effect on self-assembling of oxalamide gelators explored by mass spectrometry and DFT calculations. Journal of the American Society for Mass Spectrometry, 28 (1), 103-113 doi:10.1007/s13361-017-1834-5.
doi -
Tandarić, T., Vrček, V. & Šakić, D. (2016) Quantum Chemical Study of HOCl-Induced Transformations of Carbamazepine. Organic & biomolecular chemistry, 14, 10866-10874 doi:10.1039/C6OB02166B.
doi -
Šakić, D., Šonjić, P., Tandarić, T. & Vrček, V. (2014) Chlorination of N-Methylacetamide and Amide-Containing Pharmaceuticals : Quantum-Chemical Study of the Reaction Mechanism. The journal of physical chemistry. A, 118 (12), 2367-2376 doi:10.1021/jp5012846.
doi
Theses
Doctoral dissertation
-
Tandarić, T. (2021) 'Computational investigation of the mechanism of the irreversible inhibition of the monoamine oxidase B enzyme', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.
repozitorij.pmf.unizg.hr
Membership in professional associations / societies
Croatian Chemical Society 2016- present