Dr. Zrinka Karačić
Ruđer Bošković Institute
Bijenička 54
HR-10000 Zagreb
Awards and Achievements
2015 FEBS Short-Term Fellowship, for project „Investigation of function of dipeptidyl peptidases III in moss Physcomitrella patens using targeted gene knockouts“
Featured Publications
Karačić, Z., Ban, Ž. & Macheroux, P. (2017) A novel member of the dipeptidyl peptidase III family from Armillariella tabescens. Current Topics in Peptide & Protein Research, 18, 41-48.
Karačić, Z., Vukelić, B., Ho, G., Jozić, I., Sučec, I., Salopek-Sondi, B., Kozlović, M., Brenner, S., Ludwig-Müller, J. & Abramić, M. (2017) A novel plant enzyme with dual activity: an atypical Nudix hydrolase and a dipeptidyl peptidase III. Biological chemistry, 398 (1), 101-112 doi:10.1515/hsz-2016-0141.
Karačić, Z., Špoljarić, J., Rožman, M. & Abramić, M. (2012) Molecular determinants of human dipeptidyl peptidase III sensitivity to thiol modifying reagents. Biological chemistry, 393 (12), 1523-1532 doi:10.1515/hsz-2012-0181.
Publications
Journal articles
Scientific and review papers
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Grgić, I., Cetinić, K., Karačić, Z., Previšić, A. & Rožman, M. (2023) Fate and effects of microplastics in combination with pharmaceuticals andendocrine disruptors in freshwaters: Insights from a microcosm experiment. Science of the total environment, 859, 160387, 12 doi:10.1016/j.scitotenv.2022.160387.
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Karačić, Z., Šupljika, F., Tomić, A., Brkljačić, L., Tomašić Paić, A., Ćehić, M. & Tomić, S. (2022) Neuropeptides, substrates and inhibitors of human dipeptidyl peptidase III, experimental and computational study — A new substrate identified. International journal of biological macromolecules, 220, 1390-1401 doi:10.1016/j.ijbiomac.2022.09.119.
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Ban, Ž., Karačić, Z., Tomić, S., Amini, H., Marder, T. & Piantanida, I. (2021) Triarylborane Dyes as a Novel Non‐Covalent and Non‐Inhibitive Fluorimetric Markers for DPP III Enzyme. Molecules, 26, 4816, 20 doi:10.3390/molecules26164816.
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Agić, D., Karnaš, M., Šubarić, D., Lončarić, M., Tomić, S., Karačić, Z., Bešlo, D., Rastija, V., Molnar, M., Popović, B. & Lisjak, M. (2021) Coumarin derivatives act as novel inhibitors of human dipeptidyl peptidase III: combined in vitro and in silico study. Pharmaceuticals, 14 (6), 540, 19 doi:10.3390/ph14060540.
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Ćehić, M., Suć Sajko, J., Karačić, Z., Piotrowski, P., Šmidlehner, T., Jerić, I., Schmuck, C., Piantanida, I. & Tomić, S. (2020) The guanidiniocarbonylpyrrole - fluorophore conjugates as theragnostic tools for DPP III monitoring and inhibition. Journal of biomolecular structure & dynamics, 38 (13), 3790-3800 doi:10.1080/07391102.2019.1664936.
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Kazazić, S., Karačić, Z., Sabljić, I., Agić, D., Tomin, M., Abramić, M., Dadlez, M., Tomić, A. & Tomić, S. (2018) Conservation of the conformational dynamics and ligand binding within M49 enzyme family. RSC Advances, 8 (24), 13310-13322 doi:10.1039/c7ra13059g.
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Šmidlehner, T., Karačić, Z., Tomić, S., Schmuck, C. & Piantanida, I. (2018) Fluorescent cyanine-guanidiniocarbonyl-pyrrole conjugate with pH-dependent DNA/RNA recognition and DPP III fluorescent labelling and inhibition properties. Monatshefte für Chemie, 149 (7), 1307-1313 doi:10.1007/s00706-018-2192-0.
doi Karačić, Z., Ban, Ž. & Macheroux, P. (2017) A novel member of the dipeptidyl peptidase III family from Armillariella tabescens. Current Topics in Peptide & Protein Research, 18, 41-48. (https://www.bib.irb.hr/922418).
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Hromić-Jahjefendić, A., Jajčanin Jozić, N., Kazazić, S., Grabar Branilović, M., Karačić, Z., Schrittwieser, J., Das, K., Tomin, M., Oberer, M., Gruber, K., Abramić, M. & Tomić, S. (2017) A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain. PLoS One, 12 (11), e0188915, 27 doi:10.1371/journal.pone.0188915.
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Matovina, M., Agić, D., Abramić, M., Matić, S., Karačić, Z. & Tomić, S. (2017) New findings about human dipeptidyl peptidase III based on mutations found in cancer. RSC Advances, 7 (58), 36326-36334 doi:10.1039/C7RA02642K.
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Karačić, Z., Vukelić, B., Ho, G., Jozić, I., Sučec, I., Salopek-Sondi, B., Kozlović, M., Brenner, S., Ludwig-Müller, J. & Abramić, M. (2017) A novel plant enzyme with dual activity: an atypical Nudix hydrolase and a dipeptidyl peptidase III. Biological chemistry, 398 (1), 101-112 doi:10.1515/hsz-2016-0141.
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Agić, D., Brkić, H., Tomić, S., Karačić, Z., Špoljarević, M., Lisjak, M., Bešlo, D. & Abramić, M. (2017) Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: experimental and computational approach. Chemical biology & drug design, 89 (4), 619-627 doi:10.1111/cbdd.12887.
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Gundić, M., Tomić, A., Wade, R., Matovina, M., Karačić, Z., Kazazić, S. & Tomić, S. (2016) Human DPP III – Keap1 Interactions : A Combined Experimental And Computational study. Croatica chemica acta, 89 (2), 217-228 doi:10.5562/cca2916.
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Abramić, M., Karačić, Z., Šemanjski, M., Vukelić, B. & Jajčanin-Jozić, N. (2015) Aspartate 496 from the subsite S2 drives specificity of human dipeptidyl peptidase III. Biological chemistry, 396 (4), 359-366 doi:10.1515/hsz-2014-0247.
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Karačić, Z., Špoljarić, J., Rožman, M. & Abramić, M. (2012) Molecular determinants of human dipeptidyl peptidase III sensitivity to thiol modifying reagents. Biological chemistry, 393 (12), 1523-1532 doi:10.1515/hsz-2012-0181.
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Theses
Doctoral dissertation
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Karačić, Z. (2018) 'Biochemical characterization of a dual enzymatic activity hydrolase from moss Physcomitrella patens', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.
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