Potential molecular mechanisms included in the loop (KIAA1967/DBC1 -HIC1 - SIRT1 - p53) dysregulation.
Proposed goals of the Project:
a) investigating molecular mehcanisms of dysregulated molecular loop: KIAA1967/DBC1-HIC1-SIRT1-p53, in vitro;
b) Investigating functional consequences of selective SIRT1 silencing, in vitro.
Other associates
Koraljka Gall Trošelj, Ph.D.
Ruben Pio Oses, Ph.D.
Luis Montuenga Badia, Ph.D.