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The role of Sirtuin1 in non-small cell lung cancer, NSCLC

The role of Sirtuin1 in non-small cell lung cancer, NSCLC

Potential molecular mechanisms included in the loop (KIAA1967/DBC1 -HIC1 - SIRT1 - p53) dysregulation.

Category
Projekti Hrvatske zaklade za znanost

Principal investigator

Proposed goals of the Project:

a) investigating molecular mehcanisms of dysregulated molecular loop: KIAA1967/DBC1-HIC1-SIRT1-p53, in vitro;

b) Investigating functional consequences of selective SIRT1 silencing, in vitro.