The main goal of this project is to investigate MSI and EMAST microsatellite instability in sporadic colon cancer and to correlate the obtained results with clinico-pathological characteristics of tumors and patients.

The main goal of this study is to investigate hereditary and sporadic genetic changes in benign and malignant gastrointestinal tumors in order to elucidate the mechanisms of their development and progression. Another goal of this study is to start with prospective pharmacogenetic study in order to examine the correlation between known polymorpisms and gastrointestinal cancer therapy.