Maja Sabol

Maja Sabol

PhD

research associate
+385 1 456 1110

1849
1510

Krilo 5/306

Bijenicka 54
10002 Zagreb
Croatia

CV SABOL M 11.2018.docx 81.39 kB

Education

1999 –  2004: Univeristy of Zagreb, Faculty of Science, Department of Biology, graduate study of molecular biology

2005 –  2010: University of Zagreb, Faculty of Science, Department of Biology, postgraduate study of molecular and cell biology

2009 – 2013: Accredited private college for business and administration “Baltazar Adam Krčelić” – specialist study of project management (MBA equivalent)

workshops:

2015.     Phenomin – European Advanced School for Mouse Phenogenomics, Alsace, France

2015.     Processing and analysis of Microscopic Images in Biomedicine, Prague, Czech Republic

2012.     International Workshop on miRNA and Virus-Associated Cancers, Dubrovnik, Croatia

10th International Summer School on Biophysics, Rovinj, Croatia, September 19 - October 1, 2009

DMMC: Epigenetics: From mechanisms to medicines, Dublin, Ireland, June 24-26, 2007

MedILS Summer School ’08: Hottest topics in protein research. Split, Croatia, July 19-26, 2008

EMBO Practical Course on Ubiquitin and SUMO, MedILS, Split, Croatia, September 12-19, 2008

Specific research interests

hedgehog signaling pathway, ovarian cancer, gene editing

Awards and Achievements

Rector's award from the University of Zagreb in academic year 2002/2003

Best poster award (3rd place) at the IV Croatian Conference on Human Genetics, Malinska, Croatia 2007.

Best poster award at the Rudjer Boskovic Institute ZS3V festival (“Znanstveni susreti treće vrste”, eng. “Scientific Encounters of the Third Kind”), in the “Human – From Cell to Organism” topic

Classes

Teaching assistant in graduate courses:

- “Signaling pathways and interactions”, Division of Biotechnology, University of Rijeka 2009/10

- “Recombinant DNA methodology”, University of Applied Health Studies, Specialist study of environmental health engineering 2008/09, 2009/10

Teaching assistant in postgraduate courses:

- Signaling pathways in the cell (oncogenes and tumor suppressors), University of Zagreb, Faculty of Science 2009/10, 2010/11

- Genomic DNA, Molecular Biosciences, joint course of University of Dubrovnik, University of Osijek and Rudjer Boskovic Institute 2009/10

- Research methods in molecular oncology, University of Zagreb, School of Medicine 2009/10, 2010/11

Featured Publications

Cretnik  M, Musani V, Oreskovic S, Leovic D, Levanat S. The Patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas. Int J Mol Med 2007; 19: 875-883.

Cvok ML, Cretnik M, Musani V, Ozretic P, Levanat S. New sequence variants in BRCA1 and BRCA2 genes detected by high-resolution melting analysis in an elderly healthy female population in Croatia, Clin Chem Lab Med 2008;46(10):1376-1383.

Leovic D, Sabol M, Ozretic P, Musani V, Car D, Marjanovic K, Zubcic V, Sabol I, Sikora M, Grce M, Glavas-Obrovac Lj, Levanat S. Hh-Gli signaling pathway activity in oral and oropharyngeal squamous cell carcinoma. Head Neck 2012, 34(1): 104-12.

Sabol M, Trnski D, Uzarevic Z, Ozretic P, Musani V, Rafaj M, Cindric M, Levanat S. Combination of cyclopamine and tamoxifen promotes survival and migration of breast cancer cells – interaction of Hedgehog-gli and estrogen receptor signaling pathways. PLoS ONE 2014, 9(12):e114510.

Levanat S,Sabol M, Musani V, Ozretic P, Trnski D. Hedgehog signaling pathway as genetic and epigenetic target in ovarian tumors. Curr Pharm Des 2017,  23(1):73-94.

Trnski D,Sabol M, Gojević A, Martinić M, Ozretić P, Musani V, Ramić S, Levanat S. GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer – Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation. Biochym Biophys Acta 2015, 1852(12):2574-84.

Membership in professional associations / societies

Member of HGD (Croatian Society of Human Genetics) – affiliate of ESHG (European Society of Human Genetics)

Member of HDBMB (Croatian Society of Biochemistry and Molecular Biology) – affiliate of FEBS (Federation of the Societies of Biochemistry and Molecular Biology)

Treasurer of HDIR (Croatian Association for Cancer Research) – affiliate of EACR (European Association of Cancer Research)

Miscellaneous

Participation in RBI Open Days in 2005, 2008 and 2010

Member of the organizing committee of MedILS Summer School 2008  “Hottest topics in protein research”

Assistant on a workshop “EMBO Practical Course on Ubiquitin and SUMO”  2008

Member of the Organizing Committee of the HDIR-1, HDIR-2 and HDIR-4 “From Bench to Clinics” – first, second and fourth meeting of the Croatian Association for Cancer Research 2010

One of the translators of EuroGenTest official brochures (English to Croatian)

Member of the Assistants Council at Rudjer Boskovic Institute 2007-2011

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