dr. sc. Maja Sabol
10002 Zagreb
Obrazovanje
1999 – 2004: Sveučilište u Zagrebu, Prirodoslovno-matematički fakultet, Biološki odsjek, dodiplomski studij molekularne biologije
2005 – 2010: Sveučilište u Zagrebu, Prirodoslovno-matematički fakultet, Biološki odsjek, poslijediplomski studij molekularne i stanične biologije
2009 – 2013: Visoka škola za poslovanje i upravljanje "Baltazar Adam Krčelić", specijalistički stručni studij projektnog menadžmenta
sudjelovanje na radionicama:
2015. Phenomin – European Advanced School for Mouse Phenogenomics, Alsace, France
2015. Processing and analysis of Microscopic Images in Biomedicine, Prague, Czech Republic
2012. International Workshop on miRNA and Virus-Associated Cancers, Dubrovnik, Croatia
10th International Summer School on Biophysics, Rovinj, Hrvatska, 19.9. - 1.10. 2009.
DMMC: Epigenetics: From mechanisms to medicines, Dublin, Irska, 24-26. 6. 2007.
MedILS Summer School ’08: Hottest topics in protein research. Split, Hrvatska, 19-26. 7. 2008.
EMBO Practical Course on Ubiquitin and SUMO, MedILS, Split, Hrvatska, 12-19. 9. 2008.
Projekti
2019-2022 HRZZ IP-01-2018-4889 "Regulacija GLI koda u tumorima ovisnim o BRAF/NRAS mutacijama"
Nagrade i priznanja
Rektorova nagrada Sveučilišta u Zagrebu, školske godine 2002/2003.
Nagrada za najbolji poster (3. mjesto) na IV Hrvatskom kongresu humane genetike (Malinska, Hrvatska) 2007.
Nagrada za najbolji poster unutar teme "Čovjek - od stanice do organizma" na ZS3V, IRB (Zagreb, Hrvatska) 2011.
Nastava
asistent u nastavi (dodiplomski studiji):
- “Signalni putevi i interakcije”, Sveučilište u Rijeci, Zavod za biotehnologiju, šk.g. 2009/10.
- “Metode rekombinantne DNA”, Zdravstveno veleučilište u Zagrebu, specijalistički studij sanitarnog inženjerstva, šk.g. 2008/09, 2009/10.
asistent u nastavi (poslijediplomski studiji):
- "Signalni putevi u stanici: onkogeni i tumor supresori" Sveučilište u Zagrebu, PMF, šk.g. 2009/10, 2010/11.
- "Genomska DNA" Molekularne bioznanosti, združeni studij Sveučilišta u Dubrovniku, Sveučilišta u Osijeku i Instituta "Ruđer Bošković", šk.g. 2009/10.
- "Metode istraživanja u molekularnoj onkologiji", Sveučilište u Zagrebu, Medicinski fakultet, šk.g. 2009/10, 2010/11.
Istaknute publikacije
Cretnik M, Musani V, Oreskovic S, Leovic D, Levanat S. The Patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas. Int J Mol Med 2007; 19: 875-883.
Cvok ML, Cretnik M, Musani V, Ozretic P, Levanat S. New sequence variants in BRCA1 and BRCA2 genes detected by high-resolution melting analysis in an elderly healthy female population in Croatia, Clin Chem Lab Med 2008;46(10):1376-1383.
Leovic D, Sabol M, Ozretic P, Musani V, Car D, Marjanovic K, Zubcic V, Sabol I, Sikora M, Grce M, Glavas-Obrovac Lj, Levanat S. Hh-Gli signaling pathway activity in oral and oropharyngeal squamous cell carcinoma. Head Neck 2012, 34(1): 104-12.
Sabol M, Trnski D, Uzarevic Z, Ozretic P, Musani V, Rafaj M, Cindric M, Levanat S. Combination of cyclopamine and tamoxifen promotes survival and migration of breast cancer cells – interaction of Hedgehog-gli and estrogen receptor signaling pathways. PLoS ONE 2014, 9(12):e114510.
Trnski D,Sabol M, Gojević A, Martinić M, Ozretić P, Musani V, Ramić S, Levanat S. GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer – Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation. Biochym Biophys Acta 2015, 1852(12):2574-84.
Levanat S, Sabol M, Musani V, Ozretic P, Trnski D. Hedgehog signaling pathway as genetic and epigenetic target in ovarian tumors. Curr Pharm Des 2017, 23(1):73-94.
Ozretić P, Trnski, D, Musani V, Maurac I, Kalafatić D, Orešković S, Levanat S, Sabol M. Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas. International journal of oncology, 51 (2017), 6; 1869-1877.
Sabol M, Trnski D, Musani V, Ozretić P, Levanat S. Role of GLI transcription factors in pathogenesis and their potential as new therapeutic targets. Int J Mol Sci, 19 (2018), 2562.
Trnski D, Gregorić M, Levanat S, Ozretić P, Rinčić N, Majić Vidaković T, Kalafatić D, Maurac I, Orešković S, Sabol M, Musani V. Regulation of Survivin isoform expression by GLI proteins in ovarian cancer. Cells, 8 (2019) 128.
Publikacije - Uredničke knjige
Zbornik radova s konferencije
HDIR-1 "From bench to clinic" : first meeting with international participation : book of abstracts / Sabol, Maja ; Levanat, Sonja (ur.). Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2010
Publikacije - prilozi u knjigama
Izvorni znanstveni rad
Sobočanec, Sandra ; Šarić, Ana ; Korolija, Marina ; Marjanović, Marko ; Kralj, Marijeta ; Knežević, Jelena ; Čretnik, Maja ; Balog, Tihomir ; Šverko, Višnja ; Kušić, Borka et al. | Native propolis in vivo: On the oxidative/antioxidative effect and the mechanism of the action // Scientific evidence of the Use of Propolis in Ethnomedicine. | Lahti: Research Signpost, 2008. str. 121-131
Čretnik, Maja ; Grbeša, Ivana ; Levanat, Sonja ; Gall-Trošelj, Koraljka | Određivanje metiliranosti DNA obradom DNA bisulfitom te određivanjem slijeda nukleotida // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 376-379
Publikacije - prilozi u časopisima
Izvorni znanstveni rad
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Piteša, Nikolina ; Kurtović, Matea ; Bartoniček, Nenad ; Gkotsi, Danai S ; Čonkaš, Josipa ; Petrić, Tina ; Musani, Vesna ; Ozretić, Petar ; Riobo-Del Galdo, Natalia ; Sabol, Maja | Signaling switching from Hedgehog-GLI to MAPK signaling potentially serves as a compensatory mechanism in melanoma cell lines resistant to GANT-61 // Biomedicines, 11 (2023), 1353, 19. doi: 10.3390/biomedicines11051353
doiwww.mdpi.comfulir.irb.hr -
Kurtović, Matea ; Piteša, Nikolina ; Bartoniček, Nenad ; Ozretić, Petar ; Musani, Vesna ; Čonkaš, Josipa ; Petrić, Tina ; King, Cecile ; Sabol, Maja | RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines // Cancers, 14 (2022), 18; 4540, 20. doi: 10.3390/cancers14184540
doiwww.mdpi.comwww.ncbi.nlm.nih.govfulir.irb.hr -
Radić, Martina ; Vlašić, Ignacija ; Jazvinšćak Jembrek, Maja ; Horvat, Anđela ; Tadijan, Ana ; Sabol, Maja ; Dužević, Marko ; Herak Bosnar, Maja ; Slade, Neda | Characterization of Vemurafenib-Resistant Melanoma Cell Lines Reveals Novel Hallmarks of Targeted Therapy Resistance // International journal of molecular sciences, 23 (2022), 17; 9910, 19. doi: 10.3390/ijms23179910
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Trnski, Diana ; Sabol, Maja ; Tomić, Sanja ; Štefanac, Ivan ; Mrčela, Milanka ; Musani, Vesna ; Rinčić, Nikolina ; Kurtović, Matea ; Petrić, Tina ; Levanat, Sonja et al. | SHH-N non-canonically sustains androgen receptor activity in androgen-independent prostate cancer cells // Scientific reports, 11 (2021), 1; 14880, 11. doi: 10.1038/s41598-021-93971-6
doiwww.nature.comdoi.orgfulir.irb.hr -
Zubčić, Vedran ; Rinčić, Nikolina ; Kurtović, Matea ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja ; Leović, Dinko ; Sabol, Maja | GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3beta // International journal of molecular sciences, 21 (2020), 6410, 13. doi: 10.3390/ijms21176410
doiwww.mdpi.comfulir.irb.hr -
Sabol, Maja ; Akbudak, Aydin A. ; Fricova, Dominika ; Beck, Inken ; Sedlacek, Radislav | Novel TALEN-generated mCitrine-FANCD2 fusion reporter mouse model for in vivo research of DNA damage response // DNA repair, 94 (2020), 102936, 6. doi: 10.1016/j.dnarep.2020.102936
doiwww.sciencedirect.comdoi.org -
Ozretić, Petar ; Hanžić, Nikolina ; Proust, Bastien ; Sabol, Maja ; Trnski, Diana ; Radić, Martina ; Musani, Vesna ; Ciribilli, Yari ; Milas, Ivan ; Puljiz, Zvonimir et al. | Expression profiles of p53/p73, NME and GLI families in metastatic melanoma tissue and cell lines // Scientific reports, 9 (2019), 1; 12470, 13. doi: 10.1038/s41598-019-48882-y
doiwww.nature.comwww.nature.comfulir.irb.hr -
Sušac, Ilona ; Ozretić, Petar ; Gregorić, Maja ; Levačić Cvok, Mirela ; Sabol, Maja ; Levanat, Sonja ; Trnski, Diana ; Eljuga, Domagoj ; Seiwerth, Sven ; Aralica, Gorana et al. | Polymorphisms in survivin (BIRC5 gene) are associated with age of onset in breast cancer patients // Journal of oncology, 2019 (2019), 3483192, 10. doi: 10.1155/2019/3483192
doifulir.irb.hrwww.hindawi.comdoi.org -
Trnski, Diana ; Gregorić, Maja ; Levanat, Sonja ; Ozretić, Petar ; Rinčić, Nikolina ; Majić Vidaković, Tajana ; kalafatić, Držislav ; Maurac, Ivana ; Orešković, Slavko ; Sabol, Maja et al. | Regulation of Survivin Isoform Expression by GLI Proteins in Ovarian Cancer // Cells, 8 (2019), 2; 128, 13. doi: 10.3390/cells8020128
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Ozretić, Petar ; Trnski, Diana ; Musani, Vesna ; Maurac, Ivana ; Kalafatić, Držislav ; Orešković, Slavko ; Levanat, Sonja ; Sabol, Maja | Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas // International journal of oncology, 51 (2017), 6; 1869-1877. doi: 10.3892/ijo.2017.4156
doidoi.orgwww.spandidos-publications.com -
Levanat, Sonja ; Sabol, Maja ; Musani, Vesna ; Ozretić, Petar ; Trnski, Diana | Hedgehog Signaling Pathway as Genetic and Epigenetic Target in Ovarian Tumors // Current pharmaceutical design, 23 (2017), 1; 73-94. doi: 10.2174/1381612822666161006154705
doidx.doi.orgbenthamscience.com -
Trnski, Diana ; Sabol, Maja ; Gojević, Ante ; Martinić, Marina ; Ozretić, Petar ; Musani, Vesna ; Ramić, Snježana ; Levanat, Sonja | GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer — Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation // Biochimica et biophysica acta. Molecular basis of disease, 1852 (2015), 12; 2574-2584. doi: 10.1016/j.bbadis.2015.09.005
doiwww.sciencedirect.com -
Ozretić, Petar ; Bisio, Alessandra ; Musani, Vesna ; Trnski, Diana ; Sabol, Maja ; Levanat, Sonja ; Inga, Alberto | Regulation of human PTCH1b expression by different 5' untranslated region cis-regulatory elements // RNA Biology, 12 (2015), 3; 290-304. doi: 10.1080/15476286.2015.1008929
doiwww.tandfonline.com -
Sabol, Maja ; Trnski, Diana ; Užarević, Zvonimir ; Ozretić, Petar ; Musani, Vesna ; Rafaj, Maja ; Cindrić, Mario ; Levanat, Sonja | Combination of cyclopamine and tamoxifen promotes survival and migration of MCF-7 breast cancer cells – interaction of Hedgehog-Gli and Estrogen receptor signaling pathways // PLoS One, 9 (2014), 12; 1-23. doi: 10.1371/journal.pone.0114510
doijournals.plos.orgfulir.irb.hrurn.nsk.hr -
Musani, Vesna ; Sabol, Maja ; Car, Diana ; Ozretić, Petar ; Kalafatić, Držislav ; Maurac, Ivana ; Orešković, Slavko ; Levanat, Sonja | PTCH1 gene polymorphisms in ovarian tumors: Potential protective role of c.3944T allele // Gene, 517 (2013), 1; 55-59. doi: 10.1016/j.gene.2012.12.089
doiwww.sciencedirect.comdx.doi.org -
Sabol, Maja ; Car, Diana ; Musani, Vesna ; Ozretić, Petar ; Orešković, Slavko ; Weber, Igor ; Levanat, Sonja | The Hedgehog signaling pathway in ovarian teratoma is stimulated by Sonic Hedgehog which induces internalization of Patched // International journal of oncology, 41 (2012), 4; 1411-1418. doi: 10.3892/ijo.2012.1554
doiwww.spandidos-publications.comfulir.irb.hr -
Levanat, Sonja ; Musani, Vesna ; Levačić Cvok, Mirela ; Sušac, Ilona ; Sabol, Maja ; Ozretić, Petar ; Car, Diana ; Eljuga, Domagoj ; Eljuga, Ljerka ; Eljuga, Damir | Three novel BRCA1/BRCA2 mutations in breast/ovarian cancer families in Croatia // Gene, 498 (2012), 2; 169-176. doi: 10.1016/j.gene.2012.02.010
doiwww.sciencedirect.comdx.doi.org -
Maurac, Ivana ; Sabol, Maja ; Musani, Vesna ; Car, Diana ; Ozretić, Petar ; Kalafatić, Držislav ; Orešković, Slavko ; Babić, Damir ; Levanat, Sonja | A low grade ovarian carcinoma case with coincident LOH of PTCH1 and BRCA1, and a mutation in BRCA1 // International journal of gynecological pathology, 31 (2012), 3; 264-271. doi: 10.1097/PGP.0b013e31823b6f0f
doijournals.lww.com -
Musani, Vesna ; Sabol, Maja ; Car, Diana ; Ozretić, Petar ; Orešković, Slavko ; Leović, Dinko ; Levanat, Sonja | LOH of PTCH1 region in BCC and ovarian carcinoma: microsatellite vs. HRM analysis // Frontiers in bioscience (Elite ed.), 4 (2012), 3; 1049-1057. doi: 10.2741/E440
doifulir.irb.hrwww.imrpress.com -
Leović, Dinko ; Sabol, Maja ; Ozretić, Petar ; Musani, Vesna ; Car, Diana ; Marjanović, Ksenija ; Zubčić, Vedran ; Sabol, Ivan ; Sikora, Miroslav ; Grce, Magdalena et al. | Hh-Gli signaling pathway activity in oral and oropharyngeal squamous cell carcinoma // Head and neck-journal for the sciences and specialties of the head and neck, 34 (2012), 1; 104-112. doi: 10.1002/hed.21696
doionlinelibrary.wiley.com -
Ozretić, Petar ; Levačić Cvok, Mirela ; Musani, Vesna ; Sabol, Maja ; Car, Diana ; Levanat, Sonja | In silico analysis of potential structural and functional significance of human breast cancer gene BRCA2 sequence variants found in 5' untranslated region // Periodicum biologorum, 112 (2010), 4; 469-474
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Lof-Ohlin, Zarah ; Levanat, Sonja ; Sabol, Maja ; Sorbe, Bengt ; Nilsson, Torbjorn K. | Promoter methylation in the PTCH gene in cervical epithelial cancer and ovarian cancer tissue as studied by eight novel Pyrosequencing assays // International journal of oncology, 38 (2010), 3; 685-692. doi: 10.3892/ijo.2010.889
doiwww.spandidos-publications.comfulir.irb.hr -
Musani, Vesna ; Čretnik, Maja ; Šitum, Mirna ; Basta-Juzbašić, Aleksandra ; Levanat, Sonja | Gorlin Syndrome Patient with Large Deletion in 9q22.32-q22.33 Detected by Quantitative Multiplex Fluorescent PCR // Dermatology (Basel), 219 (2009), 2; 111-118. doi: 10.1159/000219247
doiwww.karger.com -
Čretnik, Maja ; Poje, Gorazd ; Musani, Vesna ; Krušlin, Božo ; Ozretić, Petar ; Tomas, Davor ; Šitum, Mirna ; Levanat, Sonja | Involvement of p16 and PTCH in pathogenesis of melanoma and basal cell carcinoma // International journal of oncology, 34 (2009), 4; 1045-1050. doi: 10.3892/ijo_00000230
doiwww.spandidos-publications.comdoi.org -
Willems, Petra ; Magri, V. ; Čretnik, Maja ; Fasano, Mauro ; Jakubowska, Ania ; Levanat, Sonja ; Lubinski, J. ; Marras, E. ; Musani, Vesna ; Thierens, Hubert et al. | Characterization of the c.190T>C missense mutation in BRCA1 codon 64 (Cys64Arg) // International journal of oncology, 34 (2009), 4; 1005-1015. doi: 10.3892/ijo_00000226
doiwww.spandidos-publications.comfulir.irb.hr -
Sabol, Ivan ; Čretnik, Maja ; Hadžisejdić, Ita ; Si-Mohammed, Ali ; Matovina, Mihaela ; Grahovac, Blaženka ; Levanat, Sonja ; Grce, Magdalena | A New Approach for the Evaluation of the Human Papillomavirus Type 16 Variability with High Resolution Melting Analysis // Journal of virological methods, 162 (2009), 1-2; 142-147. doi: 10.1016/j.jviromet.2009.07.029
doidx.doi.orgfulir.irb.hr -
Bura, Miljenko ; Musani, Vesna ; Čretnik, Maja ; Botica, Iva ; Levanat, Sonja | Hedgehog-Patched pathway aberrations in a malignant triton tumor case study // Oncology reports, 20 (2008), 2; 347-352. doi: 10.3892/or_00000013
doiwww.spandidos-publications.comfulir.irb.hr -
Levačić Cvok, Mirela ; Čretnik, Maja ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja | New sequence variants in BRCA1 and BRCA2 genes detected by high-resolution melting analysis in an elderly healthy female population in Croatia // Clinical chemistry and laboratory medicine, 46 (2008), 10; 1376-1383. doi: 10.1515/CCLM.2008.307
doiwww.degruyter.comfulir.irb.hr -
Čretnik, Maja ; Musani, Vesna ; Orešković, Slavko ; Leović, Dinko ; Levanat, Sonja | The Patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas // International journal of molecular medicine, 19 (2007), 6; 875-883. doi: 10.3892/ijmm.19.6.875
doiwww.spandidos-publications.comfulir.irb.hr
Pregledni rad (znanstveni)
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Petrić, Tina ; Sabol, Maja | Why 3D in vitro cancer models are the futureof cancer research? // Periodicum biologorum, 124 (2023), 3-4; 69-83. doi: 10.18054/pb.v124i3-4.24697
doihrcak.srce.hrfulir.irb.hr -
Čonkaš, Josipa ; Sabol, Maja ; Ozretić, Petar | ‘Toxic Masculinity’: What Is Known about the Role of Androgen Receptors in Head and Neck Squamous Cell Carcinoma // International journal of molecular sciences, 24 (2023), 4; 3766, 18. doi: 10.3390/ijms24043766
doiwww.mdpi.comfulir.irb.hr -
Petrić, Tina ; Sabol, Maja | Let’s Go 3D! New Generation of Models for Evaluating Drug Response and Resistance in Prostate Cancer // International journal of molecular sciences, 24 (2023), 6; 5293, 22. doi: 10.3390/ijms24065293
doiwww.mdpi.comfulir.irb.hr -
Di Fiore, Riccardo Di ; Suleiman, Sherif ; Ellul, Bridget ; O’Toole, Sharon A. ; Savona-Ventura, Charles ; Felix, Ana ; Napolioni, Valerio ; Conlon, Neil T. ; Erson-Bensan, Ayse Elif ; Kahramanoglu, Ilker et al. | GYNOCARE Update: Modern Strategies to Improve Diagnosis and Treatment of Rare Gynecologic Tumors—Current Challenges and Future Directions // Cancers, 13 (2021), 3; 493, 14. doi: 10.3390/cancers13030493
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Di Fiore, Riccardo ; Suleiman, Sherif ; Pentimalli, Francesca ; O'Toole, Sharon ; O'Leary, John ; Ward, Mark P ; Conlon, Neil T. ; Sabol, Maja ; Ozretić, Petar ; Erson-Bensan, Ayse Elif et al. | Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview // International journal of molecular sciences, 22 (2021), 8; 3822, 26. doi: 10.3390/ijms22083822
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Di Fiore, Riccardo ; Suleiman, Sherif ; Felix, Ana ; O'Toole, Sharon ; O'Leary, John J ; Ward, Mark P ; Beirne, James ; Sabol, Maja ; Ozretić, Petar ; Yordanov, Angel et al. | An Overview of the Role of Long Non-Coding RNAs in Human Choriocarcinoma // International journal of molecular sciences, 22 (2021), 12; 6506, 16. doi: 10.3390/ijms22126506
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Sabol, Maja ; Calleja-Agius, Jean ; Di Fiore, Riccardo ; Suleiman, Sherif ; Ozcan, Sureyya ; Ward, Mark P. ; Ozretić, Petar | (In)Distinctive Role of Long Non-Coding RNAs in Common and Rare Ovarian Cancers // Cancers, 13 (2021), 5040, 36. doi: 10.3390/cancers13205040
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Sabol, Maja ; Trnski, Diana ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja | Role of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets // International journal of molecular sciences, 19 (2018), 9; 2562, 37. doi: 10.3390/ijms19092562
doiwww.mdpi.comfulir.irb.hrwww.mdpi.com -
Car, Diana ; Sabol, Maja ; Musani, Vesna ; Ozretić, Petar ; Levanat, Sonja | Epigenetic regulation of the Hedgehog-Gli signaling pathway in cancer // Periodicum biologorum, 112 (2010), 4; 419-423
hrcak.srce.hr -
Levanat, Sonja ; Čretnik, Maja ; Musani, Vesna | Hh-Gli Signaling Pathway Functions and its Therapeutic Potential in Cancer // Croatica chemica acta, 81 (2008), 1; 1-5
hrcak.srce.hr
Pismo uredniku
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Maurac, Ivana ; Sabol, Maja ; Car, Diana ; Čačev, Tamara ; Levanat, Sonja | In reply // International journal of gynecological pathology, 32 (2013), 2; 177-177. doi: 10.1097/01.pgp.0000427319.75615.d7
doijournals.lww.com
Prikaz, osvrt, kritika
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Musani, Vesna ; Ozretić, Petar ; Trnski, Diana ; Sabol, Maja ; Poduje, Sanja ; Tošić, Mateja ; Šitum, Mirna ; Levanat, Sonja | Potential hot spot for de novo mutations in PTCH1 gene in Gorlin syndrome patients: a case report of twins from Croatia // Croatian medical journal, 59 (2018), 1; 20-24. doi: 10.3325/cmj.2018.59.20
doiwww.ncbi.nlm.nih.govwww.cmj.hr
Publikacije - prilozi sa skupa (u zborniku)
Sažetak izlaganja sa skupa
Užarević, Zvonimir ; Čretnik, Maja ; Car, Diana ; Ozretić, Petar ; Musani, Vesna ; Levanat, Sonja | Hh-Gli signaling pathway activity in breast cancer cell lines // Proceedings of Abstracts of 10th Croatian Biological Congress. | Zagreb: Hrvatsko biološko društvo, 2009. str. 96-97
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Čretnik, Maja ; Musani, Vesna ; Orešković, Slavko ; Leović, Dinko ; Levanat, Sonja | Detection of Loss of Heterozygosity in the Patched Gene by High-resolution Melting Approach // 10th International Summer School on Biophysics : Supramolecular Structure and Function : Book of Abstracts. | Zagreb: Institut Ruđer Bošković, 2009. str. 94-94
www.fens.org Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar ; Levanat, Sonja | Nove nukleotidne promjene gena BRCA1 i BRCA2 u zdravih žena u Hrvatskoj // Zbornik sažetaka znanstvenog simpozija "50 godina molekularne biologije u Hrvatskoj". | Zagreb: Institut Ruđer Bošković, 2009. str. 99-99
Sabol, Ivan ; Čretnik, Maja ; Hadžisejdić, Ita ; Grahovac, Blaženka ; Levanat, Sonja ; Grce Magdalena | Human Papillomavirus (HPV) Type 16 Variability in Croatia Assessed by High Resolution Melting (HRM) Method // Abstract Book 25th International Papillomavirus Conference. | 2009. str. 31:8-31:8
Čretnik, Maja ; Ozretić, Petar ; Orešković, Slavko ; Weber, Igor ; Levanat, Sonja | Hh-Gli signaling affects cell cycle progression in ovarian dermoid primary cell lines. // EMBO Meeting: Cellular Signaling & Molecular Medicine. | Split, 2008. str. 153-153
Musani, Vesna ; Poje, Gorazd ; Čretnik, Maja ; Šitum, Mirna ; Levanat, Sonja | Melanomas and basal cell carcinomas of the skin use Hh-gli signaling for cell cycle regulation // EMBO Meeting Cellular Signaling & Molecular Medicine. | Split: European Molecular Biology Organization (EMBO), 2008. str. 168-169
Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar ; Levanat, Sonja | Nasljedni rak dojke-molekularna genetička analiza // 2. godišnji sastanak Hrvatskog društva za internističku onkologiju HLZ-a i 3. radni sastanak radne grupe za onkološku farmaciju bolničke sekcije HFD-a : Knjiga sažetaka. | Zagreb: Hrvatski liječnički zbor, 2008. str. 44-44
Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar ; Orešković, Slavko ; Weber, Igor ; Levanat, Sonja | Mechanisms of activation of Hh-Gli signaling pathway in ovarian dermoid primary cell lines // Book of Abstracts of the HDBMB2008. | Osijek: Grafika Osijek, 2008. str. 114-114
Ozretić, Petar ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | Računalna analiza mogućih funkcionalnih efekata novih neklasificiranih nukleotidnih promjena gena BRCA1 i BRCA2 pronađenih u zdravih žena u Hrvatskoj // Zbornik sažetaka znanstvenog simpozija "50 godina molekularne biologije u Hrvatskoj". | Zagreb: Institut Ruđer Bošković, 2008. str. 100-100
Ozretić, Petar ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | In Silico Prediction of Potential Functional and Structural Effects of Novel BRCA1 and BRCA2 Unclassified Sequence Variants Found in Healthy Females in Croatia // Book of Abstracts of the HDBMB2008. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2008. str. 118-118
Čretnik, Maja ; Ozretić, Petar ; Orešković, Slavko ; Weber, Igor ; Levanat, Sonja | Expression and localization of Hedgehog-Gli signalling pathway proteins in ovarian dermoids // MedILS Summer School '08: Hottest topics in protein research. | Split, 2008. str. 31-31
Sabol, Ivan ; Matovina, Mihaela ; Grce, Magdalena | Otkriće nove varijante papiloma virusa čovjeka tipa 16 // Zbornik sažetaka znanstvenog simpozija "50 godina molekularne biologije u Hrvatskoj". | Zagreb: Institut Ruđer Bošković, 2008. str. 110-110
Sobočanec, Sandra ; Šarić, Ana ; Korolija, Marina ; Marjanović, Marko ; Kralj, Marijeta ; Knežević, Jelena ; Čretnik, Maja ; Marotti, Tatjana ; | Dvojaka uloga nativnog propolisa in vivo kao posljedica selektivne ekspresije gena // Peti Hrvatski kongres farmakologije i Drugi Kongres hrvatskog društva fiziologa, Osijek 2007. | 2007
Sobočanec, Sandra ; Šarić, Ana ; Korolija, Marina ; Marjanović, Marko ; Kralj, Marijeta ; Knežević, Jelena ; Čretnik, Maja ; Marotti, Tatjana | Dual effect of native propolis in vivo as a consequence of selective gene expression // Workshop on "Functional Genomics and Proteomics in Molecular Medicine. | 2007. str. 77-77
Levanat, Sonja ; Musani, Vesna ; Čretnik, Maja ; Orešković, Slavko | Signal transduction in tumors: HH-GLI interactions and therapeutic potential // International Journal of Molecular Medicine. | Atena: Lychnia, 2006. str. S13-x
Levanat, Sonja ; Musani, Vesna ; Cretnik, Maja ; Oresković, Slavko | HH-GLI interactions in different tumors and therapeutic potential // EMBO Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells. | Rim: European Molecular Biology Organization (EMBO), 2006. str. 1-3-x
Marković, Maja ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | Mutation in SMO might not be responsible for impaired signal transduction in human BCC // 9th International Summer School on Biophysics: Supramolecular Structure and Function - Book of Abstracts. | Zagreb: Institut Ruđer Bošković, 2006. str. 147-147
Marković, Maja ; Čretnik, Maja ; Musani, Vesna ; Levanat, Sonja | Mutations in SMO in human BCC might contribute to impaired signal transduction // FEBS Special Meeting Cellular Signaling : Program and Abstracts. | Zagreb: Institut Ruđer Bošković, 2006. str. 99-100
Musani, Vesna ; Čretnik, Maja ; Orešković, Slavko ; Levanat, Sonja | Methylation status of PTCH promoter in tumors with alterations in Hh-Gli signaling pathway // Book of Abstracts of the HDBMB 2006. | Zagreb, 2006. str. 80-80
Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | Polymorphisms of BRCA1 and BRCA2 genes in normal population // Congress of the Croatian Society of Biochemistry and Molecular Biology on the occasion of the 30th anniversary with international participation : book of abstracts. | Zagreb: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB), 2006. str. 82-82
Toševski, Vinko ; Čretnik, Maja ; Levanat, Sonja | Immortalisation of primary tumor cells by transformation with hTERT telomerase gene // Book of Abstracts of the HDBMB 2006. | Zagreb, 2006. str. 142-142
Čretnik, Maja ; Tomasović, Ana ; Blažević, Sofija ; Orešković, Slavko ; Levanat, Sonja | Primary cultures - a model for expression analysis of HH-GLI signaling pathway // Book of Abstracts of the HDBMB 2006. | Zagreb, 2006. str. 94-94
Levanat, Sonja ; Musani, Vesna ; Levačić Cvok, Mirela ; Čretnik, Maja | Molecular signaling in breast cancer // Book of abstracts : XIV S.I.S. World congress on breast diseases. | Zagreb: Medimond International Proceedings, 2006. str. 7-12
Publikacije - prilozi sa skupa (u časopisu)
Sažetak izlaganja sa skupa
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Ozretić, Petar ; Musani, Vesna ; Sabol, Maja ; Car, Diana ; Levanat, Sonja | Computational Analysis of Novel BRCA1 and BRCA2 Genes Unclassified Sequence Variants Found in Healthy Females in Croatia // The FEBS journal, 2010. str. 18-18
febs.onlinelibrary.wiley.com Ozretić, Petar ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | High-Resolution Melting Analysis of BRCA1 and BRCA2 Sequence Variants in Healthy Women in Croatia and Computational Analysis of New Variants of Unknown Clinical Significance // Paediatria Croatica. Supplement, 2009. str. 12-12
Levanat, Sonja ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar | Sequence variants in BRCA1 and BRCA2 genes detected by high-resolution melting analysis as a tool in molecular genetic analysis of inherited breast cancers // European journal of cancer. Supplement (1990), 2009. str. 315-315
Levanat, Sonja ; Čretnik, Maja ; Musani, Vesna ; Ozretić, Petar ; Orešković, Slavko | Hedgehog-Gli signaling pathway interactions and therapeutic potential in proliferative tumors of the ovary // International journal of molecular medicine, 2009. str. S9-S9
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Levanat, Sonja ; Cretnik, Maja ; Musani, Vesna ; Oreskovic, Slavko | Interactions and therapeutic potential of Hedgehog-Gli signaling pathway genes in ovarian tumors // The FEBS journal, 2009. str. 68-68
febs.onlinelibrary.wiley.com -
Ozretić, Petar ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | Computational analysis of 5' and 3' untranslated regions of breast cancer genes BRCA1 and BRCA2 // The FEBS journal, 2009. str. 116-116
febs.onlinelibrary.wiley.com -
Musani, Vesna ; Čretnik, Maja ; Levačić Cvok, Mirela ; Ozretić, Petar ; Šitum, Mirna ; Leović, Dinko ; Levanat Sonja | Mutations of Hh-Gli Signaling Pathway Genes in Basal Cell Carcinomas (BCCs) // European journal of human genetics, 2009. str. 167-167
www.eshg.org Sabol, Ivan ; Čretnik, Maja ; Grce, Magdalena | Potential Application of High Resolution Melting Analysis in HPV Variants Determination // Central European journal of public health, 2008. str. S57-S57
Levanat, Sonja ; Levačić Cvok, Mirela ; Čretnik, Maja, Musani, Vesna ; Ozretić, Petar | BRCA1 and BRCA2 sequence variants in healthy women in Croatia analyzed by high-resolution melting and in silico analysis of variants of unknown clinical significance // European journal of cancer. Supplement (1990), 2008. str. 98-98
Levanat, Sonja ; Čretnik, Maja ; Ozretić, Petar ; Weber, Igor ; Orešković, Slavko | Hh-Gli signaling in tumors ; Hh-Gli activation and effects on cell cycle progression // European journal of cancer. Supplement (1990), 2008. str. 95-95
Willems, P. ; Levanat, Sonja ; Magri, V. ; Jakubowska, A. ; Vandersickel, V. ; Musani, Vesna ; Čretnik, Maja ; Marras, E. ; Perletti, G. ; Vral, A. | Molecular and genetic characterization of the T309C missense transversion in BRCA1 codon 64 (C64R) // International journal of molecular medicine, 2008. str. S23-S23
Ozretić, Petar ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | In Silico Analysis of BRCA1 and BRCA2 Sequence Variants of Unknown Clinical Significance: Application to Variants Found in Healthy Women in Croatia // European journal of human genetics, 2008. str. 206-207
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Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar ; Levanat, Sonja | BRCA1 and BRCA2 sequence variants in healthy women in Croatia // European journal of human genetics, 2008. str. 367-368
www.eshg.org Levanat, Sonja ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar | Molecular diagnostics of inherited breast cancers // Clinical chemistry and laboratory medicine, 2008, A241, 1
Levanat, Sonja ; Čretnik, Maja ; Musani, Vesna ; Orešković, Slavko | Interactions and therapeutic potential of Hh-Gli pathway genes in different tumors // International journal of molecular medicine, 2007. str. 42-42
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Musani, Vesna ; Levačić Cvok, Mirela ; Čretnik, Maja ; Ozretić, Petar ; Godan, Ana ; Marković, Maja ; Levanat, Sonja | BRCA1 and BRCA2 sequence variability in normal population in Croatia // European journal of human genetics, 2007, P0505, 1
www.eshg.org Čretnik, Maja ; Blažević, Sofia Ana ; Tomasović, Ana ; Orešković, Slavko ; Levanat, Sonja | Expression analyses of Hh-Gli signaling pathway related genes in ovarian dermoid primary cultures // The FEBS journal, 2007. str. 176-176
Ozretić, Petar ; Konjevoda, Paško ; Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Levanat, Sonja | Statistical evaluation of experimental data based on the high-resolution melting approach - application to BRCA1 polymorphisms // Paediatria Croatica, 2007. str. 164-164
Musani, Vesna ; Čretnik, Maja ; Leović, Dinko ; Levanat, Sonja | Hedgehog signaling pathway and basal cell carcinomas (BCC) // Paediatria Croatica, 2007. str. 163-163
Levačić Cvok, Mirela ; Musani, Vesna ; Čretnik, Maja ; Ozretić, Petar ; Levanat, Sonja | BRCA1 and BRCA2 polymorphism screening in healthy women in Croatia // Paediatria Croatica, 2007. str. 163-163
Čretnik, Maja ; Musani, Vesna ; Orešković, Slavko ; Levanat, Sonja | Genetic and epigenetic regulation of Hh-Gli signaling pathway in ovarian tumors // Paediatria Croatica, 2007. str. 162-162
Čretnik, Maja ; Musani, Vesna ; Levačić Cvok, Mirela ; Ozretić, Petar ; Levanat, Sonja | BRCA1 and BRCA2 polymorphisms in Croatia-frequencies in healthy population // International journal of molecular medicine, 2007. str. 42-42
Čretnik, Maja ; Musani, Vesna ; Levanat, Sonja | Methylation status of PTCH promoter in tumors with alterations in HH-GLI signaling pathway // International journal of molecular medicine, 2006, S14, 1
Musani, Vesna ; Levačić Cvok, Mirela ; Čretnik, Maja ; Levanat, Sonja | Physiological significance of polymorphisms in BRCA1 and BRCA2. Difference in melting profile reflecting polymorphic or mutational variability // International journal of molecular medicine, 2006, S13, 1
Publikacije - prilozi sa skupa (neobjavljeni)
Neobjavljeni prilog sa skupa
Čretnik, Maja ; Ozretić, Petar ; Orešković, Slavko ; Weber, Igor ; Levanat, Sonja | Hh-Gli activation in dermoid cells: different effects on cell cycle and protein localization // Hedgehog signaling in development and disease | Palo Alto (CA), Sjedinjene Američke Države; Stanford (CA), Sjedinjene Američke Države, 20.06.2008-22.06.2008
Levanat, Sonja ; Čretnik, Maja ; Poje, Gorazd ; Musani, Vesna ; Orešković, Slavko | Different tumors require Hh-Gli signaling through cell cycle regulation // Hedgehog signaling in development and disease | Palo Alto (CA), Sjedinjene Američke Države; Stanford (CA), Sjedinjene Američke Države, 20.06.2008-22.06.2008
Publikacije - ocjenski radovi
Diplomski rad (sveučilišni)
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Brtan, Lucija | Konstrukcija i validacija vektora za ekspresiju represorskog oblika proteina GLI3 u stanicama čovjeka / Sabol, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2023
repozitorij.pmf.unizg.hr -
Vučemilo, Nikolina | Uspostava trodimenzionalne sferoidne kulture stanica tumora glave i vrata / Sabol, Maja ; Blažević, Sofia Ana (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2022
urn.nsk.hr -
Brtan, Ana | Karakterizacija i validacija sojeva stanične linije melanoma dobivenih ugradnjom sekvence SHH u genom / Sabol, Maja ; Blažević, Sofia Ana (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2021
urn.nsk.hr -
Čonkaš, Josipa | Konstrukcija vektora za ekspresiju proteina SHH u staničnoj liniji melanoma čovjeka CHL-1 / Sabol, Maja ; Blažević, Sofia Ana (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2021
urn.nsk.hr -
Rinčić, Nikolina | Izrada "knock out" stanične linije za gen GLI1 primjenom sustava CRISPR/Cas9 / Sabol, Maja ; Blažević, Sofia Ana (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2018
urn.nsk.hr
Doktorski rad
Piteša, Nikolina | Interakcija signalnih puteva RAS/RAF/MAPK i Hedgehog-GLI u rezistenciji na lijekove u staničnim linijama melanoma čovjeka / Maja Sabol (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, 2023
Publikacije - druge vrste radova
Izvještaj
Sabol, Maja | 1. kongres Hrvatskog društva za istraživanje raka // Medix : specijalizirani medicinski dvomjesečnik (1331-3002) 91 (2011) ; 25, 2011
Članstva u profesionalnim udrugama / društvima
Hrvatsko društvo za humanu genetiku /HDHG) - član
Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB) - član
Hrvatsko društvo za istraživanje raka (HDIR) - rizničar
Sudjelovanje u Otvorenim danima IRB-a 2005, 2008 i 2010.
Član organizacijskog odbora MedILS-ove međunarodne ljetne škole “Hottest topics in protein research” 2008.
Asistent na radionici “EMBO Practical Course on Ubiquitin and SUMO” 2008.
Član organizacijskog odbora HDIR-1, HDIR-2 i HDIR-4 "From Bench to Clinic" - prve, druge i četvrte konferencije Hrvatskog društva za istraživanje raka, te HDIR-5 "Translating Science to Medicine: Targets and Therapeutics", pete konferencije Hrvatskog društva za istraživanje raka
Jedan od prevoditelja brošura u izdanju EuroGenTest-a (s engleskog na hrvatski jezik)
Član Vijeća asistenata IRB-a 2007-2011.