Faculty of Science, University of Zagreb 2016 - 2021

• PhD in chemistry, Chemistry department
• Doctoral thesis: "Computational investigation of the mechanism of the irreversibleinhibition of the monoamine oxidase B enzyme", thesis supervisor Dr. Robert Vianello

Faculty of Pharmacy and Biochemistry, University of Zagreb 2011 - 2016

• Master od medicinal chemistry
• Master thesis: "Mechanism of chlorination reaction between 5-fluorouracil." thesis supervisor Dr. Valerije Vrček
• Student practice at Department of Medicinal Chemistry, University Hospital for Tumors, Zagreb (Croatia)

XV. gymnasium Zagreb 2007.-2011. 

Elemetary school OŠ Murterski škoji Murter 1999.-2007.

• 2021: Scholarship of the Austrian Academy of Arts and Sciences (JESH - Croatia) for a stay of six months in Max Perutz labs (Vienna, Austria)
• Annual Ruđer Bošković Institute award for published scientific paper in 2019 and 2020
• 09/2019: Thiene poster award, 16th European Symposium of Organic Reactivity, Dubrovnik
• 2019: French Government Scholarship for a one-month stay at the Sorbonne University (Paris, France).
• Recipient of the Annual Dean's Award for Scientific Work "Chlorination of N-Methylacetamide and Amide-Containing Pharmaceuticals. Quantum- Chemical Study of the Reaction Mechanism. " published in scientific Journal of Physical Chemistry A for the academic year 2013/2014.
• Recipient of the Annual Dean's Award for Student Research "The chemical fate of antiepileptics neutrophile. In silico research of reaction mechanism with hypochlorous acid ." for the academic year 2014/2015.

General chemistry with stoichiometry, seminars, Faculty of Pharmacy and Biochemistry, University of Zagreb, 2019/2020.

Izvorni znanstveni rad

• Šakić, Davor ; Šonjić, Pavica ; Tandarić, Tana ; Vrček, Valerije | Chlorination of N-Methylacetamide and Amide-Containing Pharmaceuticals : Quantum-Chemical Study of the Reaction Mechanism // The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical, 118 (2014), 12; 2367-2376. doi: 10.1021/jp5012846

  doipubs.acs.orgpubs.acs.org

• Tandarić, Tana ; Vrček, Valerije ; Šakić, Davor | Quantum Chemical Study of HOCl-Induced Transformations of Carbamazepine // Organic & biomolecular chemistry, 14 (2016), 10866-10874. doi: 10.1039/C6OB02166B

  doipubs.rsc.org

• Dabić, Dario ; Brkljačić, Lidija ; Tandarić, Tana ; Žinić, Mladen ; Vianello, Robert ; Frkanec, Leo ; Kobetić, Renata | The Metal effect on self-assembling of oxalamide gelators explored by mass spectrometry and DFT calculations // Journal of the American Society for Mass Spectrometry, 28 (2018), 1; 103-113. doi: 10.1007/s13361-017-1834-5

  doidx.doi.orglink.springer.com

• Tandarić, Tana ; Vianello, Robert | Design of Exceptionally Strong Organic Superbases Based on Aromatic Pnictogen Oxides: Computational DFT Analysis of the Oxygen Basicity in the Gas Phase and Acetonitrile Solution // The journal of physical chemistry. A, 122 (2018), 5; 1464-1471. doi: 10.1021/acs.jpca.7b11945

  doipubs.acs.org

• Hok, Lucija ; Ulm, Lea ; Tandarić, Tana ; Krivohlavek, Adela ; Šakić, Davor ; Vrček, Valerije | Chlorination of 5-fluorouracil: Reaction mechanism and ecotoxicity assessment of chlorinated products // Chemosphere, 207 (2018), 18; 612-619. doi: 10.1016/j.chemosphere.2018.05.140

  doiwww.sciencedirect.com

• Matić, Josipa ; Šupljika, Filip ; Tandarić, Tana ; Dukši, Marko ; Piotrowski, Patryciusz ; Vianello, Robert ; Brozović, Anamaria ; Piantanida, Ivo ; Schmuck, Carsten ; Radić Stojković, Marijana | DNA/RNA recognition controlled by the glycine linker and the guanidine moiety of phenanthridine peptides // International journal of biological macromolecules, 134 (2019), 422-434. doi: 10.1016/j.ijbiomac.2019.05.063

  doiwww.sciencedirect.comdoi.orgfulir.irb.hr

• Tandarić, Tana ; Vianello, Robert | Computational Insight into the Mechanism of the Irreversible Inhibition of Monoamine Oxidase Enzymes by the Antiparkinsonian Propargylamine Inhibitors Rasagiline and Selegiline // ACS Chemical Neuroscience, 10 (2019), 8; 3532-3542. doi: 10.1021/acschemneuro.9b00147

  doipubs.acs.orgdoi.orgfulir.irb.hr

• Toma, Mateja ; Božičević, Lucija ; Lapić, Jasmina ; Djaković, Senka ; Šakić, Davor ; Tandarić, Tana ; Vianello, Robert ; Vrček, Valerije | Transacylation in Ferrocenoyl-Purines. NMR and Computational Study of the Isomerization Mechanism // Journal of organic chemistry, 84 (2019), 19; 12471-12480. doi: 10.1021/acs.joc.9b01944

  doidoi.orgpubs.acs.org

• Tandarić, Tana ; Hok, Lucija ; Vianello, Robert | From Hydrogen Peroxide-Responsive Boronated Nucleosides Towards Antisense Therapeutics – A Computational Mechanistic Study // Croatica chemica acta, 92 (2019), 2; 287-295. doi: 10.5562/cca3592

  doihrcak.srce.hrdoi.orgfulir.irb.hr

• Perković, Ivana ; Raić-Malić, Silvana ; Fontinha, Diana ; Prudêncio, Miguel ; Pessanha de Carvalho, Lais ; Held, Jana ; Tandarić, Tana ; Vianello, Robert ; Zorc, Branka ; Rajić, Zrinka | Harmicines − harmine and cinnamic acid hybrids as novel antiplasmodial hits // European journal of medicinal chemistry, 187 (2020), 111927, 16. doi: 10.1016/j.ejmech.2019.111927

  doidoi.orgwww.sciencedirect.com

• Rimac, Hrvoje ; Tandarić, Tana ; Vianello, Robert ; Bojić, Mirza | Indomethacin increases quercetin affinity for human serum albumin: a combined experimental and computational study and its broader implications // International journal of molecular sciences, 21 (2020), 16; 5740, 14. doi: 10.3390/ijms21165740

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Tandarić, Tana ; Prah, Alja ; Stare, Jernej ; Mavri, Janez ; Vianello, Robert | Hydride Abstraction as the Rate-Limiting Step of the Irreversible Inhibition of Monoamine Oxidase B by Rasagiline and Selegiline: A Computational Empirical Valence Bond Study // International journal of molecular sciences, 21 (2020), 17; 6151, 13. doi: 10.3390/ijms21176151

  doifulir.irb.hrwww.mdpi.com

• Marinović, Marina ; Perković, Ivana ; Fontinha, Diana ; Prudêncio, Miguel ; Held, Jana ; Pessanha de Carvalho, Lais ; Tandarić, Tana ; Vianello, Robert ; Zorc, Branka ; Rajić, Zrinka | Novel Harmicines with Improved Potency against Plasmodium // Molecules, 25 (2020), 19; 4376, 19. doi: 10.3390/molecules25194376

  doiwww.mdpi.comfulir.irb.hr

• Matić, Josipa ; Jukić, Marijana ; Ismaili, Hamit ; Saftić, Dijana ; Ban, Željka ; Tandarić, Tana ; Vianello, Robert ; Opačak-Bernardi, Teuta ; Glavaš-Obrovac, Ljubica ; Žinić, Biserka | 6-Morpholino- and 6-amino-9-sulfonylpurine derivatives. Synthesis, computational analysis, and biological activity // Nucleosides, nucleotides & nucleic acids, 40 (2021), 4; 470-503. doi: 10.1080/15257770.2021.1896001

  doiwww.tandfonline.comdoi.org

• Marinović, Marina ; Poje, Goran ; Perković, Ivana ; Fontinha, Diana ; Prudêncio, Miguel ; Held, Jana ; Pessanha de Carvalho, Lais ; Tandarić, Tana ; Vianello, Robert ; Rajić, Zrinka | Further investigation of harmicines as novel antiplasmodial agents: synthesis, structure-activity relationship and insight into the mechanism of action // European journal of medicinal chemistry, 224 (2021), 113687, 20. doi: 10.1016/j.ejmech.2021.113687

  doiwww.sciencedirect.comdoi.org

• Poje, Goran ; Pessanha de Carvalho, Lais ; Held, Jana ; Moita, Diana ; Prudêncio, Miguel ; Perković, Ivana ; Tandarić, Tana ; Vianello, Robert ; Rajić, Zrinka | Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents // European journal of medicinal chemistry, 238 (2022), 114408, 15. doi: 10.1016/j.ejmech.2022.114408

  doiwww.sciencedirect.comdoi.org

• Pantalon Juraj, Natalija ; Tandarić, Tana ; Tadić, Vanja ; Perić, Berislav ; Moreth, Dominik ; Schatzschneider, Ulrich ; Brozovic, Anamaria ; Vianello, Robert ; Kirin, Srećko I. | Tuning the coordination properties of chiral pseudopeptide bis(2-picolyl)amine and iminodiacetamide ligands in Zn(II) and Cu(II) complexes // Dalton transactions, 51 (2022), 44; 17008-17021. doi: 10.1039/d2dt02895f

  doipubs.rsc.org

• Matić, Josipa ; Tandarić, Tana ; Radić Stojković, Marijana ; Šupljika, Filip ; Karačić, Zrinka ; Tomašić Paić, Ana ; Horvat, Lucija ; Vianello, Robert ; Tumir, Lidija-Marija | Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme // Beilstein journal of organic chemistry, 19 (2023), 550-565. doi: 10.3762/bjoc.19.40

  doiwww.beilstein-journals.orgfulir.irb.hr

• Prieto-Díaz, Rubén; Fojo-Carballo, Hugo; Majellaro, Maria; Tandarić, Tana; Azuaje, Jhonny; Brea, José; Loza, María I.; Barbazán, Jorge; Salort, Glòria; Chotalia, Meera et al. | Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents // Biomedicine & pharmacotherapy, 173 (2024), 116345, 27. doi: 10.1016/j.biopha.2024.116345

  doiwww.sciencedirect.com

Sažetak izlaganja sa skupa

• Šonjić, Pavica ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Influence of Various Moieties on Resistance of Derivatives of Barbituric Acid in Reaction of Chlorination with Hypochlorous Acid. Quantum- Chemical Study. // XXIV. HRVATSKI SKUP KEMIČARA I KEMIJSKIH INŽENJERA Knjiga sažetaka / Ukić, Šime ; Bolanča, Tomislav (ur.). Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko društvo, 2015. str. 68-68

  www.24hskiki.hr

• Šakić, Davor ; Tandarić, Tana ; Vrček, Valerije | Why Hypochlorous Acid Chlorinates Amines Rather than Hydroxylates Them // 15th European Symposium of Organic Reactivity, Book of Abstracts / Reiner Harges (ur.). Kiehl, 2015. str. 165-165

  www.esor2015.org

• Šonjić, Pavica ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Utjecaj supstituenata na reaktivnost derivata barbiturne kiseline s hipoklornom kiselinom // 5. hrvatski kongres farmacije s međunarodnim sudjelovanjem. Farmaceutska izvrsnost u službi zdravlja. / Zorc, Branka (ur.). Rovinj: Hrvatsko farmaceutsko društvo, 2015. str. 165-165

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• Hok, Lucija ; Pem, Barbara ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | The chlorination of barbiturates. Quantum-chemical study of the reaction mechanism // 25. Hrvatski skup kemičara i kemijskih inženjera s međunarodnim sudjelovanjem ; 3. simpozij Vladimir Prelog : knjiga sažetaka = 25th Croatian Meeting of Chemist and Chemical Engineers with international participation. 3rd symposium “Vladimir Prelog” : Book of Abstracts / Ana Šantić, Marijana Đaković (ur.). Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko drustvo, 2017. str. 115-115

  drive.google.comwww.hdki.hr

• Tandarić, Tana ; Hok, Lucija ; Šakić, Davor ; Vrček, Valerije | Mehanizam reakcije između 5-fluorouracila i hipokloraste kiseline // 6. simpozij studenata farmacije i medicinske biokemije : Knjiga sažetaka / Bojić, Mirza ; Sertić, Miranda (ur.). Zagreb: Zinam d.o.o., 2017. str. 20-20

  drive.google.com

• Hok, Lucija ; Pem, Barbara ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Kloriranje barbiturata. Kvantno - kemijska studija reakcijskog mehanizma // 6. simpozij studenata farmacije i medicinske biokemije : knjiga sažetaka / Bojić, Mirza ; Sertić, Miranda (ur.). Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2017. str. 56-56

• Petrović Peroković, Vesna ; Car, Željka ; Meglić, Karlo ; Ribić, Rosana ; Tandarić, Tana ; Vianello, Robert ; Tomić, Srđanka | Novel para substituted n-aryl 3-hydroxypyridin- 4-one mannosides: synthesis, hemagglutination inhibitory properties and molecular modeling // Book of Abstracts of the 10th Joint Meeting on Medicinal Chemistry / Basarić, Nikola ; Namjesnik, Danijel ; Perković, Ivana et al. (ur.). Zagreb: Hrvatsko kemijsko društvo, 2017. str. 119-119

• Tandarić, Tana ; Vianello, Robert | Novel and efficient bicyclic guanidine catalyst for the cyclotrimerization of isocyanates : a quantum chemical study // Book of Abstracts of the 10th Joint Meeting on Medicinal Chemistry / Basarić, Nikola ; Namjesnik, Danijel ; Perković, Ivana et al. (ur.). Zagreb: Hrvatsko kemijsko društvo, 2017. str. 226-226

• Tandarić, Tana ; Vianello, Robert | Computational insight into the cyclotrimerization of isocyanates using bicyclic guanidine catalyst // 25. Hrvatski skup kemičara i kemijskih inženjera s međunarodnim sudjelovanjem ; 3. simpozij Vladimir Prelog : knjiga sažetaka = 25th Croatian Meeting of Chemist and Chemical Engineers with international participation. 3rd symposium “Vladimir Prelog” : Book of Abstracts / Šantić, Ana ; Đaković, Marijana (ur.). Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko drustvo, 2017. str. 81-81

  drive.google.comwww.hdki.hr

• Tandarić, Tana ; Vianello, Robert | Irreversible inhibition of monoamine oxidase B enzyme. A computational insight // Computational Chemistry Day : Book of Abstracts. Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 32-32

  www.pmf.unizg.hr

• Vrček, Valerije ; Hok, Lucija ; Šakić, Davor ; Toma, Mateja ; Djaković, Senka ; Lapić, Jasmina ; Tandarić, Tana | Mechanistic insights into chemical reactions via “in situ” NMR // Adriatic NMR Conference : Book of abstracts / Bregović, Nikola ; Namjesnik, Danijel ; Novak, Predrag et al. (ur.). Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 37-37

  adriatic-nmr-conference.chem.pmf.hr

• Tandarić, Tana ; Vianello, Robert | RAČUNALNI UVID U IREVERZIBILNU INHIBICIJU ENZIMA MONOAMINOOKSIDAZE B // Knjiga sažetaka 2. Simpozija doktorskih studija PMF-a. / Ines Primožić (ur.). Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 38-38

• Tandarić, Tana ; Vianello Robert | Irreversible inhibition of monoamine oxidase B enzyme. A computational insight. // Book of abstracts EFMC-ISMC 2018 XXV EFMC International Symposium on Medicinal Chemistry.. 2018. str. 417-417

• Tandarić, Tana ; Robert Vianello | Irreversible inhibition of monoamine oxidase B enzyme. A computational insight. // Book of abstracts - 5th EFMC Young Medicinal Chemist Symposium.. 2018. str. 112-112

• Tandarić, Tana ; Vianello, Robert | Computational insight into the MAO B enzyme irreversible inhibition // Computational Chemistry Day 2019, Book of abstracts. Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2019. str. 9-9

  ccd19.pharma.hr

• Tandarić, Tana ; Vianello, Robert | Irreversible inhibition of the MAO B enzyme. A computational insight into the inactivation mechanism // 17th European Symposium on Organic Reactivity (ESOR 2019), Book of abstracts / Vančik, Hrvoj ; Namjesnik, Danijel (ur.). Zagreb: Hrvatsko kemijsko društvo, 2019. str. 92-92

  esor.chem.pmf.hrwww.bib.irb.hr

• Toma, Mateja ; Božičević, Lucija ; Tandarić, Tana ; Vianello, Robert ; Šakić, Davor ; Vrček, Valerije | Reakcijski mehanizam transaciliranja ferocenoil-purina. Računalna studija // 8. Simpozij studenata farmacije i medicinske biokemije, FARMEBS 2019. - Knjiga Sažetaka / Bojić, Mirza ; Somborac Bačura, Anita (ur.). Zagreb: Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, 2019. str. 34-34

  drive.google.com

• Tandarić, Tana ; Vianello, Robert | A computational insight into the mechanism of the irreversible inhibition of monoamine oxidase enzymes by the antiparkinsonian propargylamine inhibitors rasagiline and selegiline // 18th Hellenic Symposium on Medicinal Chemistry : Abstract Book. 2021

• Hok, Lucija ; Tandarić, Tana ; Šakić, Davor ; Vrček, Valerije | Mehanizam reakcije kloriranja 5-fluorouracila i ekotoksikološka analiza kloriranih produkata // 4. Simpozij studenata kemičara : Knjiga sažetaka. Zagreb: Studentska sekcija HKD, 2017. str. 17-17

  www.hkd.hr

• Hok, Lucija ; Ulm, Lea ; Tandarić, Tana ; Krivohlavek, Adela ; Šakić, Davor ; Vrček, Valerije | Chlorination of 5-Fluorouracil: Reaction Mechanism and Ecotoxicity Assessment of Chlorinated Products // Computational Chemistry Day : Book of Abstracts. Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2018. str. 24-24

  www.pmf.unizg.hr

• Rajić, Zrinka ; Poje, Goran ; Pessanha de Carvalho, Lais ; Held, Jana ; Perković, Ivana ; Tandarić, Tana ; Vianello, Robert | Harmiquins, novel potent antiplasmodial hits // 9th BBBB International Conference on Pharmaceutical Sciences, Book of Abstracts / Obreza, Aleš ; Dreu, Rok ; Zvonar Pobirk, Alenka et al. (ur.). Ljubljana: Slovensko farmacevtsko društvo in Univerza v Ljubljani, Fakulteta za farmacijo, 2022. str. 224-225

  bbbb2022.sfd.si

• Boček, Ida ; Hok, Lucija ; Tandarić, Tana ; Hranjec, Marijana ; Vianello, Robert | Design and Development of Novel pH-Sensors Based on Iminocoumarin Derived Imidazo[4,5-b]pyridines // Computational Chemistry Day 2022 : Book of Abstracts. Zagreb: Institut Ruđer Bošković, 2022. str. 47-47

• Tandarić, Tana ; Vianello, Robert | An insight into the mechanism of the irreversible inhibition of monoamine oxidase enzymes by propargylamine inhibitors // 12th JMMC – Joint meeting on medicinal chemistry: book of abstracts / Májeková, Magdaléna ; Heger, Vladimir ; Kováčiková, Lucia et al. (ur.). Bratislava: Slovenská toxikologická spoločnosť SETOX, 2022. str. 29-29

• Boček Pavlinac, Ida ; Hok, Lucija ; Tandarić, Tana ; Hranjec, Marijana ; Vianello, Robert | Photophysical and computational study of iminocoumarin and imidazo[4,5-b]pyridines conjugates as novel pH sensitive probes // 28th Croatian Meeting of Chemists and Chemical Engineers (28HSKIKI): Book of Abstracts. Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023. str. 142-142

Diplomski rad

• Tandarić, Tana | Mehanizam reakcije kloriranja 5-fluorouracila / Vrček, Valerije (mentor); | Zagreb, Farmaceutsko-biokemijski fakultet, . 2016

Doktorska disertacija

• Tandarić, Tana | Računalno istraživanje mehanizma ireverzibilne inhibicije enzima monoamin-oksidaze B / Vianello, Robert (mentor); | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, . 2021

  repozitorij.pmf.unizg.hr

Croatian Chemical Society 2016- present