Liquid-Assisted Grinding - from Fundaments to Applications
Mechanochemistry using manual grinding or ball mill equipment is an attractive and sustainable alternative to traditional solution methods for synthesising composite solids. Using small volumes of water, liquid-assisted grinding can accelerate the kinetics reactions between different solids. The EU-funded GrindCore project aims to provide further insight into the reaction mechanisms that take place on a molecular level during liquid-assisted grinding. Researchers plan to monitor the real-time kinetic reactions of an organic compound called methylcyclohexane through advanced X-ray diffraction and Raman spectroscopy techniques. The project's results could help take this technology faster to the commercial stage. Liquid-assisted grinding produces novel solids with bespoke physical and chemical properties that can be used by the pharmaceutical industry to screen for new drugs.