Mechanochemistry using manual grinding or ball mill equipment is an attractive and sustainable alternative to traditional solution methods for synthesising composite solids. Using small volumes of water, liquid-assisted grinding can accelerate the kinetics reactions between different solids. The EU-funded GrindCore project aims to provide further insight into the reaction mechanisms that take place on a molecular level during liquid-assisted grinding. Researchers plan to monitor the real-time kinetic reactions of an organic compound called methylcyclohexane through advanced X-ray diffraction and Raman spectroscopy techniques. The project's results could help take this technology faster to the commercial stage. Liquid-assisted grinding produces novel solids with bespoke physical and chemical properties that can be used by the pharmaceutical industry to screen for new drugs.