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Testing biocompatibility of molybdenum and tungsten based nanoparticles: measuring cytotoxicity and inflammatory response in human cell lines

Principal investigator

Project type
Znanstveno-istraživački projekti
Programme
Program of scientific-technological cooperation between Republic of Croatia and Republic of Slovenia
Financier
Ministry of Science and Education of the Republic of Croatia
Start date
Jan 1st 2018
End date
Dec 31st 2019
Status
Done
Total cost
7420 HRK
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Molybdenum and tungsten nanoparticles synthesized at the Jožef Stefan Institute possess a unique form and degree of anisotropy, with confirmed antibacterial activity. In order to use nanomaterials for medical purposes it is necessary to demonstrate that once in contact with live tissue they do not cause tissue damage or allergic reaction, ie they do not induce an inflammatory response. Accordingly, it is necessary to determine the cytotoxicity of molybdenum and tungsten nanoparticles in human cells. Within this project we aim to investigate the biocompatibility of molybdenum and tungsten nanoparticles in human cells, ie examine their cytotoxicity and potentials to stimulate inflammatory response in human cells.

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