Three research groups in the Laboratory for Molecular Genetics (LMG) are studying specific evolutionarily conserved aspects of biology of the complex Streptomyces bacteria, sponges – simple ancient animals with complex genomes, and the molecular basis of adaptations in cave animals.
Main research areas within the Laboratory are:
1) posttranslational modification ADP-ribosylation in Streptomyces bacteria and its impact on metabolism, with a special focus on antibiotic production
2) studying evolutionary conserved sponge genes/proteins with an emphasis on the homologs related to human diseases, especially cancer
3) molecular basis of adaptations to novel environments using cave animals as a model