Dr. Hrvoje Fulgosi
Ruđer Bošković Institute
Bijenička 54
HR-10000 Zagreb, Croatia
Education
- 1999 - 2002 Kiel, Christian-Albrechts Universität, Germany, Group J. Soll, plant molecular biology, postdoc
- 1999 München, Ludwig-Maximilians Universität, Germany, Group R.G.Herrmann, plant molecular biology, dr. rer. nat., doctoral degree
- 1993 Zagreb, Faculty of Science, University of Zagreb, molecular and cell biology, masters degree
- 1991 Zagreb, Faculty of Science, University of Zagreb, molecular biology, university diploma
Projects
- 2012 - 2013 Croatian - Austrian bilateral project, "Proteins linking photosynthesis with antioxidative plant stress responses"
- 2012 - 2015 International Center for Genetic Engineering and Biotechnology (ICGEB), "Dissecting complex regulators of photosynthetic energy conversion"
- 2011 Croatian Academy of Sciences and Arts (HAZU), "Molecular characterization of cyanobacterial system suitable for biological production of hydrogen"
- 2011 - 2012 Croatian - German bilateral project, "Control of plant growth and senescence by energetic status of chloroplasts"
- 2010 Industrial fonds, Croatian Electric Company (HEP), "Development of advanced biological system for production of hydrogen in photosynthetic bacteria"
- 2008 - 2010 Croatian - Austrian bilateral project, "Subcellular localization of glutathione and cysteine in cyanobacteria"
- 2007 - present Ministry of Science, Education and Sports (MZOŠ), "Regulatory mechanisms of photosynthesis and differentiation of plastids"
- 1998 - 2000 Ministry of Science, Education and Sports (MZOŠ), Project for the young scientists "Regulatory mechansms of photosynthesis"
- 1991 - 1993 Open Society Fund, "Overexpression of patatin in transgenic Sollanum tuberosum plants"
Awards and Achievements
- 2011 Ruđer Bošković Institutes' Director General Prize for significant international project
- 2010 Ruđer Bošković Institutes' Director General Prize for scientific achievement
- 2002 Prize for the best research publication, Croatian Association of University Teachers and Other Scientists in Zagreb
- 1990 University of Zagreb Rector's Prize
Classes
- Course "Structure and Function of Photosynthetic Membranes", Department of Biology, Faculty of Science, Zagreb
- Course "Photosynthesis", Department of Biology, University Josip Juraj Strossmayer, Osijek
- Course "Genome Evolution", Depatrment of Biology, University Josip Juraj Strossmayer, Osijek
- Course "Genetic Engineering", Department of Biology, University Josip Juraj Strossmayer, Osijek
- Course "Microbiology", "Marko Marulić" Polytechnics, Knin
- Course "Genetic Engineering in Biotechnology", University Interdisciplinary Doctoral Study "Molecular biosciences"
- Course "Genetics and Evolution of Photosynthetic Organisms", University Interdisciplinary Doctoral Study "Molecular biosciences""
Featured Publications
- S. Puthiyaveetil, I.M. Ibrahim, B. Jeličić, A. Tomašić, H. Fulgosi, J.F. Allen: Transcriptional control of photosynthesis genes: the evolutionarily conserved regulatory mechanism in plastid genome function. Genome Biology and Evolution. 2 (2010): 888-896.
- S. Jurić, K. Hazler Pilepić, A Tomašić, H. Lepeduš, B. Jeličić, S. Puthiyaveetil, T. Bionda, L. Vojta, J.F. Allen, E. Schleiff, H. Fulgosi: Tethering of ferredoxin:NADP+ oxidoreductase to thylakoid membranes is mediated by novel chloroplast protein TROL. The Plant Journal. 60 (2009): 783-794.
- B. Boelter, A. Nada, H. Fulgosi, J. Soll: A chloroplastic inner envelope membrane protease is essential for plant development. FEBS Letters 580 (2006): 789-794.
- P. Weber, H. Fulgosi, I Piven, L. Muller, K. Krupinska, V.H. Doung, R.G. Herrmann, A. Sokolenko: TCP34, a novel nuclear-encoded response regulator-lke TPR protein of higher plant chloroplasts. Journal of Molecular Biology 357 (2006): 535-549.
- H. Fulgosi, H. Lepeduš, V. Cesar, N. Ljubešić: Differential accumulation of plastid preprotein translocon components during spurce (Picea abies. L. Karst.) needle development. Biological Chemistry 386 (2005): 777-783.
- H. Fulgosi, L. Gerdes, S. Westphal, C. Glockman, J. Soll: Cell and organelle division requires ARTEMIS. Proceedings of National Academy of Sciences USA 99 (2002): 11501-11506.
- H. Fulgosi, J. Soll: The chloroplast protein import receptors Toc34 and Toc195 are phosphorylated by distinct protein kinases. Journal of Biological Chemistry 277 (2002): 8934-8940.
- H. Fulgosi, J. Soll, S. de Faria maracshin, H. Kourthout, M. Wang, C. Testernik. 14-3-3 proteins and plant development. Plant Molecular Biology 50 (2002): 1019-1029.
- A. Vener, A Rokka, H. Fulgosi, B. Andersson, R.G: Herrmann: A cyclophilin-regulated PP2A-like protein phosphatase in thylakoid membranes of plant chloroplasts. Biochemistry USA 39 (1999): 14955-14965.
- H. Fulgosi, A. Vener, L. altschmied, R.G. Herrmann, B. Andersson: A novel multi-functional chloroplast protein: identification of a 40 kDa immunophilin-like protein located in the thylakoid lumen. EMBO Journal (1998): 1577-1587.
- A. Sokolenko, H. Fulgosi, A. Gal, L. Altschmied, I. Ohad, R.G. Herrmann: The 64 kDa polypeptide of spinach may not be the LHCII kinase, but a lumen-located polyphenol oxidase. FEBS Letters 371 (1995): 176-180.
Publications
Books and book chapters
Authored books
Bosnić, M., Antunović, B., Fulgosi, H., Capak, K., Zupan, I., Žafran Novak, J. & Ljubenko Mihelj, S. (2005) The Framework for the Development of the National Biosafety Strategy. Zagreb, Državni zavod za zaštitu prirode. (https://www.bib.irb.hr/185129).
Books and book chapters
Book chapters
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Vojta, L., Čuletić, A. & Fulgosi, H. (2018) ffects of TROL Presequence Mutagenesis on Its Import and Dual Localization in Chloroplasts. U: Sabater, B. (ur.) Chloroplast. Basel, MDPI Books, str. 365-377 doi:10.3390/books978-3-03897-337-9.
doiwww.mdpi.com Fulgosi, H., Ljubešić, N. & Wrischer, M. (2013) Regreening of yelow leaves. U: Biswal, B., Krupinska, K. & Biswal, U. (ur.) Plastid development in leaves during growth and senescence. Dordrecht, Springer, str. 589-599.
Jurić, S., Vojta, L. & Fulgosi, H. (2013) Electron transfer routes in oxygenic photosynthesis : regulatory mechanisms and new perspectives. U: Dubinsky, Z. (ur.) Photosynthesis. Rijeka, IntechOpen, str. 23-46. (https://www.bib.irb.hr/632798).
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Vojta, L. & Fulgosi, H. (2012) Energy conductance from thylakoid complexes to stromal reducing equivalents. U: Najafpour, M. (ur.) Advances in Photosynthesis - Fundamental Aspects. Rijeka, IntechOpen, str. 175-190 doi:10.5772/26693.
doi Fulgosi, H., Soll, J. & Inaba-Sulpice, M. (2004) Protein translocation machinery in chloroplasts and mitochondria: structure, function and evolution. U: Hirt, R. & Horner, D. (ur.) Organelles, genomes and eukaryote phylogeny: an evolutionary synthesis in the age of genomics. Boca Raton (FL), Routledge, str. 259-287.
Weber, P., Sokolenko, A., Eshaghi, S., Fulgosi, H., Vener, A., Andersson, B., Ohad, I. & Herrmann, R. (2001) Elements of signal transduction involved in thylakoid membrane dynamics. U: Sopory, S., Oelmueller, R. & Maeshwari, S. (ur.) Signal transduction in plants: Current Advances. Dordrecht, Kluwer Academic Publishers, str. 222-237.
Vener, A., Fulgosi, H., Andersson, B. & Herrmann, R. (1998) Regualation of thylakoid protein dephosphorylation by cyclophilin TLP40. U: Garab, G. (ur.) Photosynthesis: Mechanisms and Effects. Dordrecht, Kluwer Academic Publishers.
Weber, P., Fulgosi, H., Sokolenko, A., Karnauchov, I., Andersson, B., Ohad, I. & Herrmann, R. (1998) Evidence for four thylakoid-located protein kinases. U: Garab, G. (ur.) Photosynthesis: Mechanisms and Effects. Dordrecht, Kluwer Academic Publishers, str. 1883-1886.
Andersson, B., Fulgosi, H., Vener, A., Altschmiedt, L. & Herrmann, R. (1998) TLP40: The first complex immunophilin-lke protein in plant photosynthetic membranes. U: Garab, G. (ur.) Photosynthesis: Mechanisms and Effects. Dordrecht, Kluwer Academic Publishers.
Gal, A., Zer, H., Roobol-Boza, M., Fulgosi, H., Herrmann, R., Ohad, I. & Andersson, B. (1995) Use of perfusion chromatography for the rapid isolation of thylakoid kinase enriched preparations. U: Mathis, P. (ur.) Photosynthesis : from light to biosphere. Dordrecht, Kluwer Academic Publishers, str. 341-344.
Journal articles
Scientific and review papers
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Vončina, D., Diaz-Lara, A., Preiner, D., Al Rwahnih, M., Stevens, K., Jurić, S., Malenica, N., Šimon, S., Meng, B., Maletić, E., Fulgosi, H. & Cvjetković, B. (2022) Virus and Virus-like Pathogens in the Grapevine Virus Collection of Croatian Autochthonous Grapevine Cultivars. Plants, 11 (11), 1485, 14 doi:10.3390/plants11111485.
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Kekić, T., Fulgosi, H., Vojta, L. & Bertoša, B. (2020) Molecular basis of ferredoxin:NADP(+) reductase interactions with FNR binding domains from TROL and Tic62 proteins. Journal of molecular structure, 1215, 128281, 12 doi:10.1016/j.molstruc.2020.128281.
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Fulgosi, H. & Vojta, L. (2020) Tweaking Photosynthesis: FNR-TROL Interaction as Potential Target for Crop Fortification. Frontiers in plant science, 11, 318, 4 doi:10.3389/fpls.2020.00318.
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Rac, A. & Fulgosi, H. (2020) Qualitative and quantitative dataset of TROL protein interaction with C3 and C4 ferredoxin: NADP+ oxidoreductases. Data in brief, 28, 105038, 4 doi:10.1016/j.dib.2019.105038.
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Vojta, L., Tomašić Paić, A., Horvat, L., Rac, A., Lepeduš, H. & Fulgosi, H. (2019) Complex lumenal immunophilin AtCYP38 influences thylakoid remodelling in Arabidopsis thaliana. Journal of plant physiology, 243, 153048, 5 doi:10.1016/j.jplph.2019.153048.
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Vojta, L. & Fulgosi, H. (2019) Topology of TROL protein in thylakoid membranes of Arabidopsis thaliana. Physiologia plantarum, 166 (1, Special Issue: Photosynthesis), 300-308 doi:10.1111/ppl.12927.
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Hsueh, Y., Nicolaisen, K., Gross, L., Nöthen, J., Schauer, N., Vojta, L., Ertel, F., Koch, I., Ladig, R., Fulgosi, H., Fernie, A. & Schleiff, E. (2018) The outer membrane Omp85-like protein P39 influences metabolic homeostasis in mature Arabidopsis thaliana. Plant biology, 20 (5), 825-833 doi:10.1111/plb.12839.
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Vojta, L., Čuletić, A. & Fulgosi, H. (2018) Effects of TROL Presequence Mutagenesis on Its Import and Dual Localization in Chloroplasts. International journal of molecular sciences, 19 (2), 569, 13 doi:10.3390/ijms19020569.
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Vojta, L. & Fulgosi, H. (2016) Data supporting the absence of FNR dynamic photosynthetic membrane recruitment in trol mutants. Data in brief, 7, 393-396 doi:10.1016/j.dib.2016.02.044.
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Vojta, L., Carić, D., Cesar, V., Antunović Dunić, J., Lepeduš, H., Kveder, M. & Fulgosi, H. (2015) TROL-FNR interaction reveals alternative pathways of electron partitioning in photosynthesis. Scientific reports, 5, 10085, 9 doi::10.1038/srep10085.
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Vojta, L., Ljuma-Skupnjak, L., Budimir, A., Vukičević, S. & Fulgosi, H. (2015) Rapid transient expression of human granulocyte-macrophage colony-stimulating factor in two industrial cultivars of tobacco (Nicotiana tabacum L.) by agroinfiltration. Biotechnology reports, 7, 81-86 doi::10.1016/j.btre.2015.05.006.
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Nicolaisen, K., Missbach, S., Hsueh, Y., Ertel, F., Fulgosi, H., Sommer, M. & Schleiff, E. (2015) The Omp85-type outer membrane protein p36 of Arabidopsis thaliana evolved by recent gene duplication. Journal of plant research, 128 (2), 317-325 doi:10.1007/s10265-014-0693-4.
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Hanzer, R., Ocvirk, D., Špoljarić Marković, S. & Fulgosi, H. (2012) Monitoring of GM Soybean in High Categories of Seed on the Croatian Seed Market. Agriculturae Conspectus Scientificus, 77 (3), 127-130.
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Vojta, L., Horvat, L. & Fulgosi, H. (2012) Balancing chloroplast redox status – regulation of FNR binding and release. Periodicum biologorum, 114 (1), 25-31. (https://www.bib.irb.hr/579681).
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Fulgosi, H., Ježić, M., Lepeduš, H., Peharec Štefanić, P., Ćurković Perica, M. & Cesar, V. (2012) Degradation of chloroplast DNA during natural senescence of maple leaves. Tree physiology, 32 (3), 346-354 doi:10.1093/treephys/tps014.
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Zechmann, B., Liou, L., Koffler, B., Horvat, L., Tomašić Paić, A., Fulgosi, H. & Zhang, Z. (2011) Subcellular distribution of glutathione and its dynamic changes under oxidative stress in the yeast Saccharomyces cerevisiae. Fems yeast research, 11 (8), 631-642 doi:10.1111/j.1567-1364.2011.00753.x.
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Bauer, N., Fulgosi, H. & Jelaska, S. (2011) Overexpression of Phenylalanine Ammonia-Lyase in Transgenic Roots of Coleus blumei Alters Growth and Rosmarinic Acid Synthesis. Food technology and biotechnology, 49 (1), 24-31.
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Lepeduš, H., Gaća, V., Viljevac, M., Kovač, S., Fulgosi, H., Šimić, D., Jurković, V. & Cesar, V. (2011) Changes in photosynthetic performance and antioxidative strategies during the maturation of Norway maple (Acer platanoides L.) leaves. Plant physiology and biochemistry, 49 (4), 368-376 doi:10.1016/j.plaphy2010.12.011.
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Puthiyaveetil, S., Ibrahim, I., Jeličić, B., Tomašić, A., Fulgosi, H. & Allen, J. (2010) Transcriptional control of photosynthesis genes: the evolutionarily conserved regulatory mechanism in plastid genome function. Genome biology and evolution, 2, 888-896 doi:10.1093/gbe/evq073.
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Lepeduš, H., Jurković, V., Štolfa, I., Ćurković-Perica, M., Fulgosi, H. & Cesar, V. (2010) Changes in photosystem II photochemistry in senescing maple leaves. Croatica chemica acta, 83 (4), 379-386.
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Zechmann, B., Tomašić, A., Horvat, L. & Fulgosi, H. (2010) Subcellular distribution of glutathione and cysteine in cyanobacteria. Protoplasma, 246 (1-4), 65-72 doi:10.1007/s00709-010-0126-8.
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Škrobot Vidaček, N., Ćukušić, A., Ivanković, M., Fulgosi, H., Huzak, M., Smith, J. & Rubelj, I. (2010) Abrupt Telomere Shortening in normal human fibroblasts. Experimental gerontology, 45 (3), 235-242 doi:10.1016/j.exger.2010.01.009.
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Jurić, S., Hazler-Pilepić, K., Ana Tomašić, A., Lepeduš, H., Jeličić, B., Puthiyaveetil, S., Bionda, T., Vojta, L., Allen, J., Schleiff, E. & Fulgosi, H. (2009) Tethering of ferredoxin : NADP+ oxidoreductase to thylakoid membranes is mediated by novel chloroplast protein TROL. Plant journal, 60 (5), 783-794 doi:10.1111/j.1365-313X.2009.03999.x.
doi Lepeduš, H., Tomašić, A., Jurić, S., Katanić, Z., Cesar, V. & Fulgosi, H. (2009) Photochemistry of PSII in CYP38 Arabidopsis thaliana deletion mutant. Food Technology and Biotechnology, 47 (3), 275-280.
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Lepeduš, H., Fulgosi, H., Benšić, M. & Cesar, V. (2008) Efficiency of the photosynthetic apparatus in developing needles of Notway spruce (Picea abies L. Karst). Acta Biologica Hungarica, 59 (2), 217-232 doi:10.1556/ABiol.59.2008.2.8.
doi Prebeg, T., Wrischer, M., Fulgosi, H. & Ljubešić, N. (2008) Ultrastructural characterization of the reversible differentiation of chloroplasts in cucumber fruit. Journal of Plant Biology, 51 (2), 122-131.
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Fulgosi, H., Jurić, S., Lepeduš, H., Hazler-Pilepić, K., Prebeg, T. & Ljubešić, N. (2008) Thylakoid system disassembly during bleaching of aurea mutant of maple Acer negundo Hassk. var. Odessanum. Croatica Chemica Acta, 81 (1), 89-95.
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Vojta, A., Fulgosi, H. & Schleiff, E. (2008) The molecular concept of protein translocation across the outer membrane of chloroplasts. Croatica chemica acta, 81 (3), 501-509.
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Boelter, B., Nada, A., Fulgosi, H. & Soll, J. (2006) A chloroplastic inner envelope membrane protease is essential for plant development. FEBS letters, 580 (3), 789-794 doi:10.1016/j.febslet.2005.12.098.
doi Weber, P., Fulgosi, H., Piven, I., Muller, L., Krupinska, K., Doung, V., Herrmann, R. & Sokolenko, A. (2006) TCP34, a novel nuclear-encoded response regulator-like TPR protein of higher plant chloroplasts. Journal of Molecular Biology, 357 (2), 535-549.
Fulgosi, H., Lepeduš, H., Cesar, V. & Ljubešić, N. (2005) Differential accumulation of plastid preprotein translocon components during spruce (Picea abies L. Karst.) needle development. Biological chemistry, 386 (8), 777-783.
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Clausen, C., Ilkavets, I., Thomson, R., Philippar, K., Vojta, A., Möhlmann, T., Neuhaus, E., Fulgosi, H. & Soll, J. (2004) Intracellular localization of VDAC proteins in plants. Planta, 220 (1), 30-37 doi:10.1007/s00425-004-1325-3.
doi Fulgosi, H. & Maglica, Ž. (2003) Protein trafficking into chloroplasts - country roads or super highways. Periodicum biologorum, 105 (3), 221-228.
Fulgosi, H., Ester, L. & Ljubešić, N. (2002) Essential role of peptidyl-prolyl isomerase sll0408 in Synechocystis sp. PCC 6803 development. Periodicum biologorum, 11 (4), 413-419.
Fulgosi, H., Gerdes, L., Westphal, S., Glockman, C. & Soll, J. (2002) Cell and organelle division requires ARTEMIS. Proceedings of National Academy of Sciences USA, 99 (17), 11501-11506.
Fulgosi, H., Soll, J., de Faria Maraschin, S., Korthout, H., Wang, M. & Testerink, C. (2002) 14-3-3 proteins and plant development. Plant Molecular Biology, 50, 1019-1029.
Fulgosi, H. & Soll, J. (2002) The chloroplast protein import receptors Toc34 and Toc 195 are phosphorylated by distinct protein kinases. Journal of Biological Chemistry, 277 (11), 8934-8940.
Fulgosi, H. & Soll, J. (2001) A gateway to chloroplasts - Protein translocation and beyond. Journal of Plant Physiology, 158, 273-284.
Vener, A., Rokka, A., Fulgosi, H., Andersson, B., Herrman, N. & Reinhold, G. (1999) A cyclophilin-regulated PP2A-like protein phosphatase in thylakoid membranes of plant chloroplasts. Biochemistry, 39 (8), 2130-2130.
Fulgosi, H., Vener, A., Altschmied, L., Herrmann, R. & Andersson, B. (1998) A novel multi-functional chloroplast protein: identification of a 40 kDa immunophilin-like protein located in the thylakod lumen. EMBO journal, 17 (6), 1577-1587.
Ljubešić, N., Dugonjić, B. & Fulgosi, H. (1997) Gamma-ray-induced changes in the chloroplasts of Hamatocactus setispinus. Periodicum biologorum, 99 (1), 61-66.
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Hornung, S., Fulgosi, H., Doerfel, P. & Herrmann, R. (1996) Sequence variation in the putative replication origins of the five genetically distinct basic Euoenothera plastid chromosomes (plastomes). MGG. Molecular & general genetics, 251 (5), 609-612 doi:10.1007/BF02173651.
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Sokolenko, A., Fulgosi, H., Gal, A., Altschmied, L., Ohad, I. & Herrmann, R. (1995) LHCII kinase, but a lumen-located polyphenol oxidase. FEBS letters, 371 (2), 176-180 doi:10.1016/0014-5793(95)00892-D.
doi Fulgosi, H. & Ljubešić, N. (1992) Dynamics of plastid nocleoids changes in wild- and aurea-type leaves of Ligustrum ovalifolium Hassk. Var. Aureum. Acta Botanica Croatica, 51, 21-26.
Conference proceedings papers
Scientific conference proceedings papers
Šimić, D., Franić, M., Fulgosi, H., Lončarić, Z., Sorić, R., Jambrović, A., Ledenčan, T., Zdunić, Z., Kovačević, V. & Brkić, I. (2012) Breeding strategies for metal accumulation in maize – from conventional breeding to cisgenesis. U: Bedo, Z. & Lang, L. (ur.)Plant Breeding for Future Generations.
Fulgosi, H., Jurić, S., Tomašić, A. & Lepeduš, H. (2009) Deficiency of TROL protein causes changes in chloroplast morphogenesis. U: Pabst, M. & Zellnig, G. (ur.)Proceedings from the First Joint Meeting of Dreiländertagung and Multinational Congress on Microscopy, Vol.2.
Zechmann, B. & Fulgosi, H. (2009) Subcellular localization of glutathione and cysteine in cyanobacteria. U: Pabst, M. & Zellnig Guenther (ur.)Book of abstracts MC 2009 Volume 2: Life Sciences.
Jurić, S., Lepeduš, H., Hazler-Pilepić, K., Jeličić, B. & Fulgosi, H. (2006) TROL integrates chloroplast redox signalling. U: Dolenc-Koce, J., Vodnik, D. & Dermastija, M. (ur.)Book of abstracts - 4th Slovenian Symposium on Plant Biology with International Participation.
Fulgosi, H. (2003) Functional genomics in research on biogenesis of chloroplasts. U: Žimbrek, T. (ur.)Priopćenja XXXVIII znanstvenog skupa hrvatskih agronoma.
Theses
Doctoral dissertation
Fulgosi, H. (1999) 'Molecular characterization of auxiliary thylakoid components involved in regulation of photosynthesis', doktorska disertacija, Fakultet fuer Biologie, Muenchen.
Membership in professional associations / societies
- Croatian Genetic Society
- Croatian Society for Plant Biology
- Croatian Society for Biochemistry and Molecular Biology
- Croatian Association of Genetic Engineers
- Croatian Biological Society
- International Photosynthesis Society
- President of the GMO Council of The Government of the Republic of Croatia
- Member of the Scientific Panel for Novel Food and Feed, Croatian Food Agency
- Expert for accreditation of GMO laboratories Croatian Accreditation Agency