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A multidisciplinary approach to discover selective drugs targeting cancer stem cells: The role of potassium transport - MultiCaST

The main goal of the proposed research is to understand cancer stem cell (CSC) biology and to develop novel CSC-directed compounds. We will strive to elucidate the molecular basis of potassium ion transport involvement in CSC-phenotype acquisition, modulation and targeting and identify key mechanisms of these processes as novel biomarkers for improved diagnostic options and innovative mechanism-based therapeutic approaches.

Principal investigator: Marijeta Kralj

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