2015 Dr., University of Zagreb, Faculty of Science, Department of Chemistry, Zagreb, Croatia

2008 B.Sc., University of Zagreb, Faculty of Science, Department of Chemistry, Zagreb, Croatia

2007. award for excellent success during the study, Faculty of Science, Zagreb, Croatia

assistant in laboratory exercises in physical chemistry at Faculty of Science, University of Zagreb, Croatia

1. Antonija Tomić; Hrvoje Brkić; Antonia Matić; Sanja Tomić. Unravelling the inhibitory zinc ion binding site and the metal exchange mechanism in human DPP III. Physical chemistry chemical physics 23 (2021), 13267-13275.

2. Antonija Tomić; Gordan Horvat; Michael Ramek; Dejan Agić; Hrvoje Brkić; Sanja Tomić. New zinc ion parameters suitable for classical MD simulations of zinc metallo-peptidases. Journal of chemical information and modeling 59 (2019), 8; 3437-3453.

3. Antonija Tomić; Borislav Kovačević; Sanja Tomić. Concerted nitrogen inversion and hydrogen bonding to Glu451 are responsible for protein-controlled suppression of the reverse reaction in the human DPP III. Physical Chemistry Chemical Physics 18 (2016), 39; 27245-27256.

4. Antonija Tomić; Sanja Tomić. Hunting the human DPP III active conformation: combined thermodynamic and QM/MM calculations. Dalton transactions 43 (2015) 15503-15514.

5. Antonija Tomić; Miguel Gonzalez; Sanja Tomić. The large scale conformational change of the human DPP III - substrate preferes the "closed" form. Journal of chemical information and modeling 52 (2012) 1583-1594.

6. Antonija Tomić; Marija Abramić; Jasminka Špoljarić; Dejan Agić; David M. Smith; Sanja Tomić. Human Dipeptidyl Peptidase III: Insights into Ligand Binding from a Combined Experimental and Computational Approach, Journal of Molecular Recognition, 24 (2011) 804-814.

Journal articles

Scientific and review papers

• Karačić, Z., Šupljika, F., Tomić, A., Brkljačić, L., Tomašić Paić, A., Ćehić, M. & Tomić, S. (2022) Neuropeptides, substrates and inhibitors of human dipeptidyl peptidase III, experimental and computational study — A new substrate identified. International journal of biological macromolecules, 220, 1390-1401 doi:10.1016/j.ijbiomac.2022.09.119.

  doi

• Tomić, A. & Tomić, S. (2022) Demystifying DPP III Catalyzed Peptide Hydrolysis—Computational Study of the Complete Catalytic Cycle of Human DPP III Catalyzed Tynorphin Hydrolysis. International journal of molecular sciences, 23 (3), 1858, 24 doi:10.3390/ijms23031858.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Tomić, A., Brkić, H., Matić, A. & Tomić, S. (2021) Unravelling the inhibitory zinc ion binding site and the metal exchange mechanism in human DPP III. PCCP. Physical chemistry chemical physics, 23, 13267-13275 doi:10.1039/D1CP01302E.

  doi

• Tomić, A., Horvat, G., Ramek, M., Agić, D., Brkić, H. & Tomić, S. (2019) New zinc ion parameters suitable for classical MD simulations of zinc metallo-peptidases. Journal of chemical information and modeling, 59 (8), 3437-3453 doi:10.1021/acs.jcim.9b00235.

  doi

• Agić, D., Brkić, H., Kazazić, S., Tomić, A. & Abramić, M. (2019) Aprotinin interacts with substrate-binding site of human dipeptidyl peptidase III. Journal of Biomolecular Structure and Dynamics, 37 (14), 3596-3606 doi:10.1080/07391102.2018.1521343.

  doifulir.irb.hrdoi.orgwww.tandfonline.com

• Tomin, M., Tomić, A., Kovačević, B. & Tomić, S. (2018) The Mechanism of Peptide Hydrolysis Catalysed by Dipeptidyl Peptidase III from Bacteroides thetaiotaomicron. Croatica chemica acta, 91 (2), 187-193 doi:10.5562/cca3343.

  doihrcak.srce.hrfulir.irb.hr

• Kazazić, S., Karačić, Z., Sabljić, I., Agić, D., Tomin, M., Abramić, M., Dadlez, M., Tomić, A. & Tomić, S. (2018) Conservation of the conformational dynamics and ligand binding within M49 enzyme family. RSC Advances, 8 (24), 13310-13322 doi:10.1039/c7ra13059g.

  doipubs.rsc.orgpubs.rsc.orgfulir.irb.hr

• Sabljić, I., Tomin, M., Matovina, M., Sučec, I., Tomašić Paić, A., Tomić, A., Abramić, M. & Tomić, S. (2018) The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity. PLoS One, 13 (2), e0192488, 25 doi:10.1371/journal.pone.0192488.

  doifulir.irb.hrfulir.irb.hr

• Gundić, M., Tomić, A., Wade, R., Matovina, M., Karačić, Z., Kazazić, S. & Tomić, S. (2016) Human DPP III – Keap1 Interactions : A Combined Experimental And Computational study. Croatica chemica acta, 89 (2), 217-228 doi:10.5562/cca2916.

  doihrcak.srce.hr

• Tomić, A., Kovačević, B. & Tomić, S. (2016) Concerted nitrogen inversion and hydrogen bonding to Glu451 are responsible for protein-controlled suppression of the reverse reaction in the human DPP III. Physical Chemistry Chemical Physics, 18 (39), 27245-27256 doi:10.1039/C6CP04580D.

  doi

• Tomić, A., Berynskyy, M., Wade, R. & Tomić, S. (2015) Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding. Molecular biosystems, 11, 3068-3080 doi:10.1039/c5mb00465a.

  doi

• Tomić, A. & Tomić, S. (2014) Hunting the human DPP III active conformation : combined thermodynamic and QM/MM calculations. Dalton transactions, 43, 15503-15514 doi:10.1039/C4DT02003K.

  doi

• Tomić, A., Gonzalez, M. & Tomić, S. (2012) The large scale conformational change of the human DPP III – substrate prefers the "closed" form. Journal of chemical information and modeling, 52 (6), 1583-1594 doi:10.1021/ci300141k.

  doi

• Špoljarić, J., Tomić, A., Vukelić, B., Salopek-Sondi, B., Agić, D., Tomić, S. & Abramić, M. (2011) Human Dipeptidyl Peptidase III : the Role of Asn406 in Ligand Binding and Hydrolysis. Croatica chemica acta, 84 (2), 259-268 doi:10.5562/cca1808.

  doihrcak.srce.hr

• Tomić, A., Abramić, M., Špoljarić, J., Agić, D., Smith, D. & Tomić, S. (2011) Human Dipeptidyl Peptidase III: Insights into Ligand Binding from a Combined Experimental and Computational Approach. Journal of molecular recognition, 24 (5), 804-814 doi:10.1002/jmr.1115.

  doi

• Tomić, A. & Živković, T. (2009) On the vibrational interlacing rule in deuterated thiophenes : I. Out-of-plane vibrations. Croatica chemica acta, 82 (2), 561-566.

  hrcak.srce.hr

Conference proceedings papers

Scientific conference proceedings papers

• Tomić, S., Brkić, H., Grabar Branilović, M., Tomić, A., Branimir, B. & Mile, Š. (2013) Proteins and Nucleic Acids in Space and Time. U: Paar, V. (ur.)Bioinformatics and biological physics: proceedings of the scientific meeting. (https://www.bib.irb.hr/689340).

Theses

Doctoral dissertation

• Tomić, A. (2015) 'Multi scale computational approaches to understand a structure, dynamics and activity of the human dipeptidyl-peptidase III', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.

  repozitorij.pmf.unizg.hr

Member of the Croatian Chemical Society