Laboratory for biocolloids and surface chemistry

Laboratory for biocolloids and surface chemistry

Research in the Laboratory for biocolloids and surface chemistry is based on physico-chemical characterization of model bio(colloids) and interactions on various surfaces and interfaces. The main research goal is the design and preparation of novel, functional materials with improved physico-chemical properties, with the aimed use in biotechnology and biomedicine.

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Research in the Laboratory for biocolloids and surface chemistry is based on physico-chemical characterization of model bio(colloids) and interactions on various surfaces and interfaces. The main research goal is the design and preparation of novel, functional materials with improved physico-chemical properties, with the aimed use in biotechnology and biomedicine.

The main research directions in our laboratory are (i) physico-chemical characterization, and (ii) research of interaction mechanisms for the following systems:

a) organic/inorganic interfaces:

  • the effect of different organic additives (surface active agents, amino acids,etc.) on the formation and transformation rates and mechanisms of calcium phosphates, as well as properties of solid phase, formed in solutions and on organic matrices, at conditions close to physiological
  • the control of colloidal stability of TiO2 nanostructures (different stage of hierarchy), with the help of organic additives such as structurally different surface active agents

b) surface active agents (surfactants):

  • physico-chemical characterization and examination of structure-property relationship of new surface active agents, functionalized with biologically important groups, which includes experiments of adsorption at the air/solution surface, self-organization of surfactants in solution, as well as their thermal properties in solid state

c) model membranes:

  • interaction and effect of natural and synthetic organic molecules (flavonoids, proteins,etc.) on structural, surface, thermotropic and nanomechanical properties of model membranes at physiological conditions

d) organic and inorganic nanocarriers for drugs and bioactive molecules

  • design and characterization of organic (multilayers of polyelectrolites, liposomes) and inorganic (mesporous nanoparticles, nanotubes) nanomaterials of different morphologies for targeted drug delivery and delivery of other biologically active molecules

Atiđa Selmani

38514560941
1372

Darija Domazet Jurašin
dr.sc.

Research Associate
38514561074
1489 1727

Elizabeta Stojaković

+385 1 456 0942
1555 1489

Ina Erceg

38514560941
1372

Maja Dutour Sikirić
Ph D

Senior Research Associate
38514561074
1727

Suzana Šegota
PhD

Senior Research Associate
+385 1 456 1185
1585 1489

Tea Mihelj
Ph.D.

Senior Research Assistant
+385 1 457 1211
1311

Vida Čadež
PhD

Research Assistant
+385 1 456 1185
1585
Characterization of nanoparticles by dynamic light scattering (DLS)

Characterization of nanoparticles by dynamic light scattering (DLS)

Determination of particle size and zeta potential in suspensions by dynamic light scattering on the instrument Zetasizer Nano-ZS, Malvern.

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Light Microscopy

Light Microscopy

Light Microscopy is used for visualization of inorganic and organic crystals morphology and polymeric composites, as well as identification of lyotropic and thermotropic liquid crystals. Hot stage enables monitoring the changes of polymorphs and liquid crystals textures during heating and cooling.

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Surface Tension Measurement

Surface Tension Measurement

Surface tension measurement at the solution/air interface, and interfacial tension measurement at the liquid/liquid interface with Tensiometer K100 MK2 by using ring tear-off method.

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European and Latin American Technology based Business Network - Europa Aid Project

European and Latin American Technology based Business Network - Europa Aid Project

Glavni istraživač / voditelj: Maja Dutour Sikirić

The ELAN Network is a space for collaboration, co-generation and development of technology based business opportunities between Europe and Latin America. It brings together key European and Latin American research and innovation actors (R&I), who promote technology based transformation processes and economic growth.

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Protective mechanisms and effects of nano-delivered flavonoids  in model cell membranes and neurons (NanoFlavNeuroProtect)

Protective mechanisms and effects of nano-delivered flavonoids in model cell membranes and neurons (NanoFlavNeuroProtect)

Glavni istraživač / voditelj: Suzana Šegota

NanoFlavoNeuroProtect will pave the way towards development of inovative and improved therapies for oxidative stress-associated neurological disorders. In addition, the knowledge obtained within NanoFlavNeuroProtect could be extended to designing effective delivery systems for the incorporation, protection and release of other unstable bioactive molecules with an aim to improve human health or to increase the shelf life of pharmaceutical or food products.

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The lipid-peroxidation inhibition governed by interactions between nanocarried flavonoids and model lipid membranes

Principal investigator: Suzana Šegota

We expect to find out how the biocompatible mesoporous NPs made of silica, magnetite and/or goethite loaded with flavonoids affect the organization and fluidity of the model membranes and whether the flavonoids embedded in NPs themselves permeate through and alter the membrane structure protecting their structure under oxidative stress conditions. Within this study we hope to gain more complete understanding of the mechanism of flavonoid action at the molecular level.

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Biocompatible nanoparticles with enhanced therapeutic efficacy of flavonoids in food

Biocompatible nanoparticles with enhanced therapeutic efficacy of flavonoids in food

Glavni istraživač / voditelj: Suzana Šegota

The goal of this project is preparation of a functional prototype of biodegradable nanoparticles (NP) having built-in flavonoids as an original solution up to date not present on the market.

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 Nanostructured carriers for controlled release of flavonoids as a potential therapeutics for treatment of Alzheimers' disease

Nanostructured carriers for controlled release of flavonoids as a potential therapeutics for treatment of Alzheimers' disease

Glavni istraživač / voditelj: Suzana Šegota

The project is the unique opportunity for young researchers in both teams to exchange knowledge, skills and for their further improvement. For researchers with more experience, this will be opportunity to find more efficient approaches for Alzheimer’s disease treatment.

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