Skip to main content
  1. Ruđer Bošković Institute
  2. Research
  3. Projects
  4. A new approach in the structural...

A new approach in the structural characterization of drug delivery systems

Principal investigator

Danijela Bakarić, dr. sc.

danijela.bakaric@irb.hr

+385 1 457 1382
Project type
Znanstveno-istraživački projekti
Financier
Ruđer Bošković Institute
Start date
Jan 15th 2025
End date
Jan 14th 2026
Status
Active
Total cost
65000 EUR
More information
CroRIS project page

Liposomes, spherical structures that can incorporate water-soluble (in)soluble drugs, have proven to be very powerful therapeutics in the treatment of chronic conditions. The effectiveness of liposomes resulting from delivery to a targeted site in the body after a sufficiently long circulation in the bloodstream is, unfortunately, accompanied by shortcomings such as their aggregation and premature drug release. Since the quality of liposomes is validated by various structural and physicochemical techniques, this project proposal proposes the inclusion of two techniques in the routine protocol of their characterization. They will also improve the quality control of prepared drug carriers, and more precise design will facilitate the administration and final effect of personalized drugs.