Dr. Maja Herak Bosnar
Education
1976-1984 - elementary school, Zagreb
1984-1988 - 16. gymnasium, Zagreb
1988 - 1993 - graduate school, Faculty of Sciences and Mathematics, University of Zagreb, B.Sc. in molecular biology
1993-1996 - postgraduate study in molecular and cellular biology, Faculty of Sciences and Mathematics, University of Zagreb, M.Sc. in molecular and cellular biology
1996-2002 - doctoral study, Faculty of Sciences and Mathematics, University of Zagreb, PhD in molecular biology
Projects
2023-2027.-principal investigator: Exploring the unique properties of mitochondrial NME6 protein-EXTEND-project of the Croatian Scientifc Foundation
2017.-2021. principal investigator - "Structure, function and evolution of Nme6/Nm23-H6 gene/protein-project of the Croatian Scientifc Foundation www.irb.hr/Nemo6 2014-today-collaborator- New protein networks for novel therapeutic avenues in human melanoma, PI dr.sc. Neda Slade, Croatian Scientific Foundation 2013.-today,work package leader-FP7-Regpot project „Enhancement of the Innovation Potential in SEE through new Molecular Solutions in Research and Development“ InnoMol– coordinator: dr.sc. Oliver Vugrek 2007-2013. -principal investigator- The role of nm23 genes in oral squamous cell carcinoma, Ministry of Science, Technology and Sports, Republic of Croatia 2009-2010 -principal investigator- The study of intracellular localization and dynamics of NDPK A and B subunits (Nm23-H1 and Nm23-H2) – French-Croatian bilateral project “Cogito” 2008. –principal investigator- The role of nm23 genes in oral squamous cell carcinoma, Lutrija Hrvatske (Croatian Lottery) 2002.- 2006 collaborator,“Gene therapy using tumor-suppressor genes“ Ministry of Science, Technology and Sports, Republic of Croatia, principal investigator dr. sc. Jasminka Pavelić 1996.-2002 collaborator, projekt MZOŠ „Human tumor DNA bank“ – Ministry of Science, Technology and Sports, Republic of Croatia, principal investigator acad. Šime Spaventi 1993.-1996.collaborator– „Formation of human tumor bank for basic research“ - Ministry of Science, Technology and Sports, Republic of Croatia, principal investigator, acad. Šime Spaventi
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Awards and Achievements
Annual reward of the Ruđer Bošković Institute for the scientific publication Dominko K, Talajić A, Radić M, Vidaček NŠ, Vlahoviček K, Bosnar MH, Ćetković H. Transfection of Sponge Cells and Intracellular Localization of Cancer-Related MYC, RRAS2, and DRG1 Proteins. Mar Drugs. 2023 Feb 10;21(2):119. doi: 10.3390/md21020119. PMID: 36827160; PMCID: PMC9964533
Annual reward of the Ruđer Bošković Institute for the scientific publication Radić M, Vlašić I, Jazvinšćak Jembrek M, Horvat A, Tadijan A, Sabol M, Dužević M, Herak Bosnar M, Slade N. Characterization of Vemurafenib-Resistant Melanoma Cell Lines Reveals Novel Hallmarks of Targeted Therapy Resistance. Int J Mol Sci. 2022 Aug 31;23(17):9910. doi: 10.3390/ijms23179910. PMID: 36077308; PMCID: PMC9455970.
Annual reward of the Ruđer Bošković Institute for the scientific publication Proust B, Radić M, Škrobot Vidaček N, Cottet C, Attia S, Lamarche F, Ačkar L, Godinić Mikulčić, Tokarska-Schlattner M, Schlattner U, Herak Bosnar M. NME6 is a phosphotransfer-inactive, monomeric NME/NDPK family member and functions in complexes at the interface of mitochondrial inner membrane and matrix. Cell Bioscience 11, 1, 2021.
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Annual reward of the Ruđer Bošković Institute for the scientific publication Radić M, Šoštar M, Weber I, Ćetković H, Slade N, Herak Bosnar M*. The Subcellular Localization and Oligomerization Preferences of NME1/NME2 upon Radiation-Induced DNA Damage, Int J Mol Sci 21: 2363, 2020.
Annual reward “Josip Juraj Strossmayer“ for the best scientific publication (Croatian Academy of Science and Arts and Zagreb Fair), 2007, for the textbook: Metode u molekularnoj biologiji(Methods in Molecular Biology) (editors): Andreja Ambriović Ristov, Anamaria Brozović, Branka Bruvo Mađarić, Helena Ćetković, Maja Herak Bosnar, Dubravka Hranilović, Silva Katušić Hećimović, Nevenka Meštrović Radan, Snježana Mihaljević, Neda Slade and Dušica Vujaklija, publisher: Institut Ruđer Bošković, Zagreb, 2007. |
Classes
Course holder (PhD studies)
2008-present: Molekularne osnove metastaziranja (Molecular Basis of Metstasis Formation), doctoral study in Molekular Bioscience, University Josip Juraj Strossmayer Osijek), University in Dubrovnik and Rudjer Bošković Institute
2010-present: Genetika raka i biologija tumorskih stanica (Cancer Genetics and Tumor Cell Biology), doctoral study in Biology, Faculty of Science, University of Zagreb
Featured Publications
Stojanovic N, Brozovic A, Majhen D, Herak Bosnar M, Fritz G, Osmak M, Ambriovic-Ristov A. Integrin αβ3 expression in tongue squamous cell carcinoma cells Cal27 confers anticancer drug resistance trough loss of pSrc(Y418). BBA-Molecular Cell Research, 2016
Cetkovic H, Perina D, Harcet M, Mikoc A, Herak Bosnar M*. Nme family of proteins – clues from simple animals. N-S Arch Pharmacol 388, 133-142, 2015.
Franczalsky L, Monostori E, Farkas, Z, Pourkarimi E, Masoudi N, Hargitai B, Herak Bosnar M, Dezeljin M, Zsakaj A, Vellai T, Mehta A, Takacz-Vellai, K. NDK-1, the Homolog of NM23-H1/H” regulates cell migration and apoptotic engulfment in C. elegans. PLoS One, 9,e92687, 2014
Horvat T, Dezeljin M, Redzic I, Barisic D, Herak Bosnar M, Lauc G, Zoldos V. Reversibility of membrane N-Glycome of HeLa cells upon treatment with epigenetic inhibitors. PLoS One, 8, e54672.2013. Deželjin M, Herak Bosnar M*. Metastasis - recent scientific insights and challenging new therapeutic approaches. Periodicum biologorum 114: 453-459, 2012. Horvat T, Mužinić I, Barišić D, Herak Bosnar M, Zoldoš V. Epigenetic modulation od HeLa cell membrane N-glycome. BBA general subjects, 1820, SI, 1412-1419, 2012.
Annesley SJ, Bago R, Herak Bosnar M, Filić V, Marinović M, Weber I, Mehta A, Fisher PR. Dictyostelium discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis. PLoS One, 6:e26024. 2011.
Perina D+, Herak Bosnar M*+, Mikoč A, Müller WEG, Ćetković H. Characterization of Nme6-like gene/protein from marine sponge Suberites domuncula. N-S Arch Pharmacol 384:451-60, 2011. +Equal contribution
Perina D, Herak Bosnar M, Bago R, Mikoč A, Harcet M, Deželjin M, Ćetković H. Sponge non-metastatic Group I Nme gene/protein - structure and function is conserved from sponges to humans. BMC Evol Biol 11:87, 2011. |
Publications - authored books
Zbornik
- Levanat, Sonja ; Levačić Cvok, Mirela ; Musani, Vesna ; Car, Diana ; Osmak, Maja ; Herak Bosnar, Maja ; Slade, Neda ; Stojanović | Periodicum Biologorum HDIR-2 ''From Bench to Clinic''Second Meeting of the Croatian Association for Cancer research with International Participation. Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2012
Publications - editorial books
Priručnik
Metode u molekularnoj biologiji / Ambriović Ristov, Andreja (ur.). Zagreb: Institut Ruđer Bošković, 2007
Publications - book chapters
Stručni rad
Herak Bosnar, Maja | Transfekcija eukariotskih stanica u kulturi // Metode u molekularnoj biologiji. | Zagreb: Instutut Ruđer Bošković, 2007. str. 499-503-x
Herak Bosnar, Maja ; Bago, Ružica | Zaustavljanje i praćenje stanica u fazama staničnog ciklusa // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 83-86-x
Bago, Ružica ; Herak Bosnar, Maja | Izdvajanje genomske DNA iz uzorka pune krvi isoljavanjem // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 165-167-x
Herak Bosnar, Maja | Priprema uzoraka za razdvajanje proteina iz stanica // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 563-564-x
Herak Bosnar, Maja | Fluorescencijska mikroskopija // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 735-736-x
Herak Bosnar, Maja | Zeleni fluorescentni protein (GFP) // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 737-739-x
Herak Bosnar, Maja | Bojenje aktina fluorescentno obojenim faloidinom // Metode umolekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 739-741-x
Bago, Ružica ; Herak Bosnar, Maja | Adhezijska svojstva stanica // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 840-842-x
Publications - journal articles
Izvorni znanstveni rad
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Dominko, Kristina ; Talajić, Antea ; Radić, Martina ; Škrobot Vidaček, Nikolina ; Vlahoviček, Kristian ; Herak Bosnar, Maja ; Ćetković, Helena | Transfection of Sponge Cells and Intracellular Localization of Cancer-Related MYC, RRAS2, and DRG1 Proteins // Marine drugs, 21 (2023), 2; 119, 21. doi: 10.3390/md21020119
doiwww.mdpi.comfulir.irb.hr -
Radić, Martina ; Vlašić, Ignacija ; Jazvinšćak Jembrek, Maja ; Horvat, Anđela ; Tadijan, Ana ; Sabol, Maja ; Dužević, Marko ; Herak Bosnar, Maja ; Slade, Neda | Characterization of Vemurafenib-Resistant Melanoma Cell Lines Reveals Novel Hallmarks of Targeted Therapy Resistance // International journal of molecular sciences, 23 (2022), 17; 9910, 19. doi: 10.3390/ijms23179910
doiwww.mdpi.comdoi.orgfulir.irb.hr -
Beljan, Silvestar ; Dominko, Kristina ; Talajić, Antea ; Hloušek-Kasun, Andrea ; Škrobot Vidaček, Nikolina ; Herak Bosnar, Maja ; Vlahoviček, Kristian ; Ćetković, Helena | Structure and function of cancer-related developmentally regulated GTP-binding protein 1 (DRG1) is conserved between sponges and humans // Scientific reports, 12 (2022), 11379, 20. doi: 10.1038/s41598-022-15242-2
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Proust, Bastien ; Radić, Martina ; Škrobot Vidaček, Nikolina ; Cottet, Cécile ; Attia, Stéphane ; Lamarche, Frédéric ; Ačkar, Lucija ; Godinić Mikulčić, Vlatka ; Tokarska-Schlattner, Malgorzata ; Ćetković, Helena et al. | NME6 is a phosphotransfer-inactive, monomeric NME/NDPK family member and functions in complexes at the interface of mitochondrial inner membrane and matrix // Cell and Bioscience, 11 (2021), 1; 195, 23. doi: 10.1186/s13578-021-00707-0
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Šafranko, Silvija ; Stanković, Anamarija ; Hajra, Sugato ; Kim, Hoe Joon ; Strelec, Ivica ; Dutour-Sikirić, Maja ; Weber, Igor ; Herak Bosnar, Maja ; Grbčić, Petra ; Kraljević Pavelić, Sandra et al. | Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing // Pharmaceuticals, 14 (2021), 9; 857, 18. doi: 10.3390/ph14090857
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Radić, Martina ; Šoštar, Marko ; Weber, Igor ; Ćetković, Helena ; Slade, Neda ; Herak Bosnar, Maja | The Subcellular Localization and Oligomerization Preferences of NME1/NME2 upon Radiation-Induced DNA Damage // International journal of molecular sciences, 21 (2020), 7; 2363, 19. doi: 10.3390/ijms21072363
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Perina, Dragutin ; Korolija, Marina ; Mikoč, Andreja ; Halasz, Mirna ; Herak Bosnar, Maja ; Ćetković, Helena | Characterization of Nme5-Like Gene/Protein from the Red Alga Chondrus Crispus // Marine drugs, 18 (2020), 1; 13, 20. doi: 10.3390/md18010013
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Ozretić, Petar ; Hanžić, Nikolina ; Proust, Bastien ; Sabol, Maja ; Trnski, Diana ; Radić, Martina ; Musani, Vesna ; Ciribilli, Yari ; Milas, Ivan ; Puljiz, Zvonimir et al. | Expression profiles of p53/p73, NME and GLI families in metastatic melanoma tissue and cell lines // Scientific reports, 9 (2019), 1; 12470, 13. doi: 10.1038/s41598-019-48882-y
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Ćetković, Helena ; Herak Bosnar, Maja ; Perina, Dragutin ; Mikoč, Andreja ; Deželjin, Martina ; Belužić, Robert ; Bilandžija, Helena ; Ruiz-Trillo, Inaki ; Harcet, Matija | Characterization of a Group I Nme protein of Capsaspora owczarzaki – a close unicellular relative of animals // Laboratory investigation, 98 (2018), 3; 304-314. doi: 10.1038/labinvest.2017.134
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Ćetković, Helena ; Harcet, Matija ; Roller, Maša ; Herak Bosnar, Maja | A survey of metastasis suppressors in Metazoa // Laboratory investigation, 98 (2018), 554-570. doi: 10.1038/s41374-018-0024-9
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Stojanović, Nikolina ; Brozovic, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Fritz, Gerhard ; Osmak, Maja ; Ambriović-Ristov, Andreja | Integrin αvβ3 Expression in Tongue Squamous Carcinoma Cells Cal27 Confers Anticancer Drug Resistance Through Loss of pSrc(Y418) // Biochimica et biophysica acta. Molecular cell research, 1863 (2016), 8; 1969-1978. doi: 10.1016/j.bbamcr.2016.04.019
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Fanczalszky, Luca ; Monostori, Eszter ; Farkas, Zsolt, Pourkarimi, Ahsan ; Masoudi, Neda ; Hargitai, Balazs ; Herak Bosnar, Maja ; Deželjin, Martina ; Zsakai, Annamaria ; Vellai Tibor ; Mehta, Anil et al. | NDK-1, the Homolog of NM23-H1/H2 Regulates Cell Migration and Apoptotic Engulfment in C. elegans // PLoS One, 9 (2014), 3; e92687-e92687. doi: 10.1371/journal.pone.0092687
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Horvat, Tomislav ; Deželjin, Martina ; Redžić, Irma ; Barišić, Darko ; Herak Bosnar, Maja ; Lauc, Gordan ; Zoldoš, Vlatka | Reversibility of Membrane N-Glycome of HeLa Cells upon Treatment with Epigenetic Inhibitors // PLoS One, 8 (2013), doi: 10.1371/journal.pone.0054672
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Horvat, Tomislav ; Mužinić, Ana ; Barišić, Darko ; Herak Bosnar, Maja ; Zoldoš, Vlatka | Epigenetic modulation of HeLa cell membrane N-glycome // Biochimica et biophysica acta. G, General subjects, 1820 (2011), 9; 1412-1420. doi: 10.1016/j.bbagen.2011.12.007
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Annesley, Sarah J. ; Bago, Ružica ; Herak Bosnar, Maja ; Filić, Vedrana ; Marinović, Maja ; Weber, Igor ; Mehta, Anil ; Fisher, Paul R. | Dictyostelim discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis // PLoS One, 6 (2011), 10; e26024, 11. doi: 10.1371/journal.pone.0026024
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Perina, Drago ; Herak Bosnar, Maja ; Mikoč, Andreja ; Ćetković, Helena | Characterization of Nme6-like gene/protein from marine sponge Suberites domuncula // Naunyn-Schmiedeberg's archives of pharmacology, 384 (2011), 4/5; 451-460. doi: 10.1007/s00210-011-0635-9
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Perina, Dragutin ; Herak Bosnar, Maja ; Bago, Ružica ; Mikoč, Andreja ; Harcet, Matija ; Deželjin, Martina ; Ćetković, Helena | Sponge non-metastatic Group I Nme gene/protein - structure and function is conserved from sponges to humans // Bmc evolutionary biology, 11 (2011), 87, 0. doi: 10.1186/1471-2148-11-87
doiwww.biomedcentral.comwww.ncbi.nlm.nih.gov -
Peršec, Zoran ; Peršec, Jasminka ; Sović, Tomislav ; Romić, Željko ; Herak Bosnar, Maja ; Hrgović, Zlatko | Metastatic Prostate Cancer in an Asymptomatic Patient with an Initial Prostate-Specific Antigen (PSA) Serum Concentration of 21, 380 ng/ml // Onkologie, 33 (2010), 3; 110-112. doi: 10.1159/000277743
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Bago, Ružica ; Pavelić, Jasminka ; Maravić Vlahoviček, Gordana ; Herak Bosnar, Maja | Nm23-H1 promotes adhesion of CAL 27 cells in vitro // Molecular carcinogenesis, 48 (2009), 9; 779-789. doi: 10.1002/mc.20536
doionlinelibrary.wiley.comdoi.org Herak Bosnar, Maja ; Bago, Ružica ; Konjevoda, Paško ; Pavelić, Jasminka | Gene expression profiling of Nm23-H2 overexpressing CAL 27 cells using DNA microarray // Neoplasma, 55 (2008), 5; 447-454
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Deželjin, Martina ; Herak Bosnar, Maja ; Dubravčić, Klara ; Bago, Ružica ; Pavelić, Jasminka | The utilization of pEGFP reporter system in cell-cycle analysis of adherent cells // Periodicum biologorum, 110 (2008), 1; 73-76
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Herak Bosnar, Maja ; Dubravčić, Klara ; Bago, Ružica ; Pavelić, Jasminka | Head and neck tumor cells exhibit altered proliferation upon overexpression of nm23 genes // Croatica chemica acta, 81 (2008), 1; 183-189
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Herak Bosnar, Maja ; Bago, Ružica ; Gall-Trošelj, Koraljka ; Streichert, Thomas ; Pavelić, Jasminka | Downstream targets of nm23-H1: Gene expression profiling of CAL 27 cells using DNA microarray // Molecular carcinogenesis, 45 (2006), 8; 627-633. doi: 10.1002/mc.20243
doipubmed.ncbi.nlm.nih.gov Popović Hadžija, Marijana ; Hrašćan, Reno ; Herak Bosnar, Maja ; Zeljko, Žarko ; Hadžija, Mirko ; Čadež, Josip ; Pavelić, Krešimir ; Kapitanović, Sanja | Alterations of the DPC4 tumor-suppressor gene in renal cell carcinoma // Urological research, 32 (2004), 3; 229-235-x
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Pavelić, Krešimir ; Hadžija, Mirko ; Bedrica, Ljiljana ; Pavelić, Jasminka ; Đikić, Ivan ; Katić, Maša ; Kralj, Marijeta ; Herak Bosnar, Maja ; Kapitanović, Sanja ; Poljak-Blaži, Marija et al. | Natural zeolite clinoptilolite: new adjuvant in anticancer therapy // Journal of molecular medicine, 78 (2001), 12; 708-720
www.sciencedirect.com Pavelić, Krešimir ; Čabrijan, Tomislav ; Hrašćan, Reno ; Vrkljan, Milan ; Lipovac, Mirna ; Kapitanović, Sanja ; Gall-Trošelj, Koraljka ; Herak Bosnar, Maja ; Tomac, Aran ; Gršković, Branka et al. | Molecular pathology of hemangiopericytomas accompanied by severe hypoglycemia: oncogenes, tumor-suppressor genes and the insulin-like growth factor family // Journal of Cancer Research and Clinical Oncology, 124 (1998), 307-314-x
Pavelić, Jasminka ; Herak Bosnar, Maja ; Gall-Trošelj, Koraljka | Limitations of p53 gene intron 6 MSP1 restriction fragment lenght polymorphism analysis // European journal of cancer (1990), 34 (1998), 6; 941-942-x
Herak Bosnar, Maja ; Pavelić, Krešimir ; Križanac, Šimun ; Slobodnjak, Zoran ; Pavelić, Jasminka | Squamous cell lung carcinomas - the role of nm23-H1 gene // Journal of molecular medicine, 75 (1997), 8; 609-613-x
Herak Bosnar, Maja ; Pavelić, Krešimir ; Hrašćan, Reno ; Zeljko, Žarko ; Krhen, Ivan ; Mareković, Zvonimir ; Križanac, Šimun ; Pavelić, Jasminka | Loss of heterozygosity of the nm23-H1 gene in human renal cell carcinomas // Journal of Cancer Research and Clinical Oncology, 123 (1997), 9; 485-488
Pavelić, Jasminka ; Gall-Trošelj, Koraljka ; Herak Bosnar, Maja ; Kardum, Mirjana ; Pavelić, Krešimir | PCR amplification of DNA from archival specimens - A methodological approach // Neoplasma, 43 (1996), 2; 75-81
Pregledni rad (znanstveni)
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Beljan, Silvestar ; Herak Bosnar, Maja ; Ćetković, Helena | Rho Family of Ras-Like GTPases in Early-Branching Animals // Cells, 9 (2020), 10; 2279, 27. doi: 10.3390/cells9102279
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Herak Bosnar, Maja ; Radić, Martina ; Ćetković, Helena | A young researcher’s guide to NME/Nm23/NDP Kinase // Periodicum biologorum, 120 (2018), 1; 3-9. doi: 10.18054/pb.v120i1.6229
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Ćetković, Helena ; Halasz, Mirna ; Herak Bosnar, Maja | Sponges: A Reservoir of Genes Implicated in Human Cancer // Marine drugs, 16 (2018), 1; 20, 17. doi: 10.3390/md16010020
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Ćetković, Helena ; Perina, Dragutin ; Harcet, Matija ; Mikoč, Andreja ; Herak Bosnar, Maja | Nme family of proteins—clues from simple animals // Naunyn-Schmiedeberg's archives of pharmacology, 388 (2015), 2; 133-142. doi: 10.1007/s00210-014-1017-x
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Deželjin, Martina ; Herak Bosnar, Maja | Metastasis - recent scientific insights and challenging new therapeutic approaches // Periodicum biologorum, 114 (2012), 4; 453-459
hrcak.srce.hr -
Herak Bosnar, Maja ; Bago, Ružica ; Ćetković, Helena | Subcellular localization of Nm23/NDPK A and B isoforms : A reflection of their biological function? // Molecular and cellular biochemistry, 329 (2009), 1-2; 63-71. doi: 10.1007/s11010-009-0107-4
doilink.springer.comdoi.org Pavelić, Jasminka ; Herak Bosnar, Maja ; Kralj, Marijeta | Gene therapy: concept, current status, moral and ethical aspects // Periodicum biologorum, 106 (2004), 3; 239-244-x
Pavelić, Jasminka ; Zeljko, Žarko ; Herak Bosnar, Maja | Molecular genetic aspects of prostate transition zone lesions // Urology, 62 (2003), 607-613-x
Pregledni rad (stručni)
Herak Bosnar, Maja | Stanica // Priroda (Zagreb), 106 (2016), 1049; 69-70
Uvodnik
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Herak Bosnar, Maja ; Ćetković, Helena ; Harcet, Matija | Genetics of Marine Organisms Associated with Human Health // Marine drugs, 18 (2020), 11; 548, 3. doi: 10.3390/md18110548
doiwww.mdpi.comfulir.irb.hr
Publications - conference proceedings
Sažetak izlaganja sa skupa
Antolčić, Mia; Perina, Dragutin; Mikoč, Andreja; Herak Bosnar, Maja; Ćukušić Kalajžić, Andrea; Imešek, Mirna; Ćetković, Helena | Telomere Binding Protein TRF1 modulates the kinase activities of Nme1/2 // 10th International Congres of the NDP kinase/Nm23/awd Family (NDPK2016): Book of Abstracts. | Zagreb: Institut Ruđer Bošković, 2016. str. 42-42
Ćetković, Helena; Herak Bosnar, Maja; Perina, Dragutin; Mikoč, Andreja; Belužić, Robert; Deželjin, Martina; Ruiz- Trillo, Innaki; Harcet, Matija | Group I Nme proteins in transition to multicellularity // 10th International Congres of the NDP kinase/Nm23/awd Family (NDPK2016): Book of Abstracts. | Zagreb: Institut Ruđer Bošković, 2016. str. 9-9
Hanžić, Nikolina ; Petrović, Lidija ; Sabol, Maja ; Herak Bosnar, Maja ; Levanat, Sonja ; Slade, Neda | The expression of p53/p73 isoforms, nm23/NDPK and Gli in MEL505 melanoma cell line upon gamma-irradiation // HDBMB2016 – on the Occasion of the 40th Anniversary. | Zagreb: Hrvatsko biološko društvo, 2016. str. 83-83
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Osmak, Maja ; Fritz, Gerhard ; Ambriović Ristov, Andreja | Integrin αVβ3 expression in tongue squamous carcinoma cells CAL27 confers anticancer drug resistance through loss of pSRC(Y418) // 40th Anniversary HDBMB2016 Book of Abstracts. | Zagreb, 2016. str. 65-65
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Fritz, Gerhard ; Osmak, Maja ; Ambriović-Ristov, Andreja | De novo expression of integrin alpha v beta 3 in Cal27 cells results in pSrc (Y418) inhibition and resistance to antitumor drugs // EACR-AACR-SIC Special conference Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic Proceedings book. | 2015. str. 140-140
Ćetković, Helena; Herak Bosnar, Maja; Perina, Dragutin; Mikoč, Andreja; Belužić, Robert; Ruiz- Trillo, Innaki; Harcet, Matija | NMEGP1 Gene/Protein from Capsaspora owcarzaki - Structure, Function AND Evolution // Knjiga sažetaka Kongresa Hrvatskog društva za biokemiju i molekularnu biologiju, "Međuigra biomolekula", HDBMB 2014 / Katalinić, Maja ; Kovarik, Zrinka (ur.). | Zagreb: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB), 2014. str. 95-95
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Osmak, Maja ; Fritz, Gerhard ; Ambriović Ristov, Andreja | Integrin αvβ3 mediated drug resistance in human tongue squamous carcinoma cells // Power of viral vectors in gene therapy and basic science Book of Abstracts. | Zagreb: Recedo d.o.o, 2014. str. 1-1
Herak Bosnar, Maja ; Perina, Dragutin ; Harcet, Matija ; Mikoč, Andreja ; Deželjin, Martina ; Ćetković, Helena | Nme family members in non-bilaterian Metazoans. | 2013
Perina, Dragutin ; Mikoč, Andreja ; Ćukušić, Andrea ; Herak Bosnar, Maja ; Ćetković Helena | INTERACTION OF SPONGE NON-METASTATIC GROUP I NME GENE/PROTEIN WITH TELOMERES // "From molecules to life and back" FEBS 3+Meeting. | Rijeka: Hrvatsko Društvo za Biotehnologiju, 2012. str. 160-160
Perina, Dragutin ; Herak Bosnar, Maja ; Mikoč, Andreja ; Müller, E.G. Werner ; Ćetković Helena | Nme6-like gene/protein from marine sponge Suberites domuncula - structure, function and evolution // "From molecules to life and back" FEBS 3+Meeting. | Rijeka: Hrvatsko Društvo za Biotehnologiju, 2012. str. 274-274
Deželjin, Martina ; Herak Bosnar, Maja | The effect of Nm23-H1 expression level on migration and adhesion of Cal27 cells // From molecules to life and back FEBS3+ Meeting Book of Abstracts. | Rijeka: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB), 2012. str. 1-1
Stojanović, Nikolina ; Brozović , Anamaria ; Majhen , Dragomira ; Bressy , Christian ; Benihoud, Karim ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | OVEREXPRESSION OF INTEGRIN αVβ3 IN HUMAN LARYNGEL CARCINOMA (HEp2) AND TONGUE SQUAMOUS CARCINOMA (Cal27) CELLS: ADHESION, MIGRATION, INVASION AND RESISTANCE TO ANTITUMOR DRUGS // Book of Abstracts of the 3rd Congress of Croatian Geneticists with international participation. | 2012
Horvat, Tomislav ; Barišić, Darko ; Knežević, Ana ; Herak Bosnar, Maja ; Zoldoš, Vlatka | Epigenetic modulation of HeLa cell membrane N-glycome // Book of abstracts, 3rd Congress of Croatian geneticists with international participation. | Sveti Ivan Zelina, 2012. str. 82-82
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | OVEREXPRESSION OF αvβ3 AND αvβ5 INTEGRINS IN TONGUE SQUAMOUS CARCINOMA CELLS (Cal27) INHIBITS MIGRATION AND CONFERS RESISTANCE TO SEVERAL ANTITUMOR DRUGS // Book od Abstract FEBS/EACR advanced lecture course : Molecular Mechanisms in Signal Transduction and Cancer, Spetses-Greece, 2011. | 2011
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of integrin αVβ3 in tongue squamous carcinoma cells (CAL27) inhibits migration and confers resistance several antitumor drugs // Book od Abstract HDIR-1 From Bench to Clinic. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2010. str. 75-75
Herak Bosnar, Maja ; Perina, Dragutin ; Bago, Ružica ; Mikoč, Andreja ; Harcet, Matija ; Deželjin, Martina ; Ćetković, Helena | Characterization of ancestral-type Grope I Nm23 gene/protein - structure and function is conserved from sponges to humans // 8th International Congres of the NDP kinase/Nm23/awd Family-From Basic Science to Clinical Application, Heidelberg, Germany. | 2010
Bago, Ružica ; Herak Bosnar, Maja | Nm23-H1 overexpressing CAL 27 carcinoma cells exhibit reduced migratory and invasive potential // HDBMB 2008, Congress of the Croatian society of biochemistry and molecular biology. | Osijek, 2008. str. 97-97
Deželjin, Martina ; Herak-Bosnar, Maja | Nm23-H1 gene silencing in CAL 27 cells // HDBMB2008. | Osijek: Hrvatsko Društvo za Biotehnologiju, 2008. str. 80-80
Dezeljin, Martina ; Slade Neda ; Herak Bosnar Maja | Downregulation of nm23-H1 increases sensitivity of CAL 27 cells to cytostatics // 50 godina molekularne biologije u Hrvatskoj. | Zagreb: Institut Ruđer Bošković, 2008. str. 95-95
Perina, Dragutin ; Herak Bosnar, Maja ; Mikoč, Andreja ; Bago, Ružica ; Müller, Werner E.G. ; Ćetković, Helena | Strukturna analiza gena nm23-SD1 i biokemijska karakterizacija proteina Nm23-SD1 iz morske spužve Suberites domuncula // Zbornik sažetaka znanstvenog simpozija 50 godina molekularne biologije u Hrvatskoj. | Zagreb: Institut Ruđer Bošković, 2008
Perina, Dragutin ; Herak Bosnar, Maja ; Mikoč, Andreja ; Bago, Ružica ; Müller, Werner E.G. ; Ćetković, Helena | Nm23-SD1 protein from marine sponge Suberites domuncula // HDBMB2008 Congress of the Croatian Society of Biochemistry and Molecular Biology with international participation. | Osijek: Hrvatsko Društvo za Biotehnologiju, 2008. str. 1-1
Perina, Dragutin; Herak Bosnar, Maja; Mikoč, Andreja; Bago, Ružica; Müller, Werner E.G.; Ćetković, Helena | Nm23-SD1 protein from marine sponge Suberites domuncula // EMBO Meeting Cellular Signaling & Molecular Medicine. | Split: Mediterranean Institute for Life Sciences (MedILS), 2008. str. 201-202
Herak Bosnar, Maja ; de Gunzburg, J. ; Bago, Ružica ; Brečević, Lukrecija ; Weber, Igor ; Pavelić, Jasminka | NM23/NDPK Subunits in Head and Neck Tumor Cells : Where do they go? // Proceedings of Abstracts of the 12th World Congress on Advances in Oncology and 10th International Symposium of Molecular Medicine and Cancer Chemoprevention Symposium ; u: International Journal of Molecular Medicine. Supplement 20 (2007) (S). | Heraklion, 2007. str. S44-S44
Herak Bosnar, Maja ; de Gunzburg, Jean ; Bago, Ružica ; Weber, Igor ; Pavelić, Jasminka ; Perina, Dragutin ; Mikoč, Andreja ; Ćetković, Helena | Subcellular localization of NDPKs: How far is a sponge from a human? // 7th International Congress of the NDP Kinase/NM23/Awd Family. | Dundee, 2007
Bago, Ružica ; Marjanović, Marko ; Herak Bosnar, Maja | Overexpression of NM23-H1 enhences proliferation of CAL 27 cells // Kongres Hrvatskog društva za biokemiju i molekularnu biologiju prigodom 30. obljetnice osnutka : knjiga sažetaka. | 2006. str. 1-1
Herak Bosnar, Maja ; Gall-Trošelj, Koraljka ; Pavelić, Krešimir ; Pavelić, Jasminka | Utjecaj ektopične ekspresije gfp-Nm23-H1 na obrazac ekspresije gena u stanicama tumora glave i vrata // Paediatria Croatica. | Zagreb: Klinika za dječje bolesti, 2003. str. 4-4-x
Kušić, Borka ; Bačić, Sanja ; Herak Bosnar, Maja ; Dominis, Marija ; Antica, Mariastefania | Ikaros expression in human lymphoproliferative disorders // Signal transduction. | Zagreb: Institut Ruđer Bošković, 2000. str. 103-103-x
Kušić, Borka ; Herak Bosnar, Maja ; Bačić, Sanja ; Antica, Mariastefania | Transcription factors in human malignancies // Immunology in the next millenium. | Dunedin, 1999
Herak Bosnar, Maja ; Bačić, Sanja ; Antica, Mariastefania | Ikaros transcription factors in human leukaemia // T lymphocyte development and function. | Kerkrade, 1999
Kušić, Borka ; Gršković, Marica ; Herak Bosnar, Maja ; Bačić, Sanja ; Dominis, Marija ; Antica, Mariastefania | Transcription factors of the zinc finger family in human disorders // Annual meeting of the Croatian immunological society. | Zagreb, 1999
Herak Bosnar, Maja ; Bačić, Sanja ; Antica, Mariastefania | Ikaros gene expression in human lymphoid disorders // Periodicum Biologorum, 1997 Annual Meeting of the Croatian Immunological Society. | Zagreb: Hrvatsko prirodoslovno društvo, 1997. str. 13-13-x
Izvorni znanstveni rad
Herak Bosnar, Maja | Mikrosatelitna nestabilnost i gubitak heterozigotnosti u oboljelih od raka dojke // Zbornik radova osmog znanstvenog sastanka bolesti dojke. | Zagreb: Hrvatska akademija znanosti i umjetnosti (HAZU), 1998. str. 12-17-x
Publications - Conference journals
Sažetak izlaganja sa skupa
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Herak Bosnar, Maja ; Perina, Drago ; Harcet, Matija ; Mikoč, Andreja ; Bago, Ružica ; Deželjin, Martina ; Ćetković, Helena | The metastasis suppressor gene family Nme/Nm23/NDPK- lessons from model organisms // Libri oncologici : Croatian journal of oncology, 2016. str. 9-9
hrcak.srce.hr Stojanović, Nikolina; Brozović, Anamaria; Majhen, Dragomira; Herak Bosnar, Maja; Osmak, Maja; Fritz, Gerhard; Ambriović Ristov, Andreja | Integrin αvβ3 mediated drug resistance in human tongue squamous carcinoma cells // Periodicum biologorum. Supplement, 116, S1, 2014. str. 1-1
Horvat, Tomislav ; Barisic, Darko ; Dezeljin, Martina ; Muzinic, Ana ; Herak Bosnar, Maja ; Lauc, Gordan ; Zoldos, Vlatka | Epigenetic modulation of HeLa cell membrane N-glycome by epigenetic inhibitors and reversibility of inhibition effects in a drug-free environment // Glycoconjugate journal, 2013. str. 419-419
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Bressy, Christian ; Benihoud, Karim ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of integrin αvβ3 in human laryngel carcinoma (Hep2) and tongue squamous carcinoma (Cal27) cells: adhesion, migration, invasion and resistance to antitumor drugs // European journal of cancer (1990), 2012. str. S48-S48
Publications - Conference unpublished
Neobjavljeni prilog sa skupa
Deželjin, Martina; Ambriović-Ristov, Andreja; Herak-Bosnar, Maja | Nm23-H1 and Nm23-H2 cooperate to reduce prostate cancer cell migration // Summer school “Power of viral vectors in gene therapy and basic science” | Primošten, Hrvatska, 17.09.2014-20.09.2014
Herak Bosnar, Maja | Mogu li DNA čipovi biti od koristi u biomedicini? // Svečani sastanak hrvatskih biokemičara uz 50. obljetnicu otkrića DNA: Quo vadis, biochemia? | Zagreb, Hrvatska, 17.10.2003-17.10.2003
Herak Bosnar, Maja ; Bago, Ružica ; Gall-Trošelj, Koraljka ; Pavelić, Jasminka | Tumor metastasis supressor gene nm23-H1 promotes transcription of matrix metalloproteinase-13 in CAL 27 cells // FEBS-EMBO Advanced lecture course ; Molecular mechanisams in signal transduction and cancer | Spétses, Grčka, 01.01.2003-01.01.2003
Publications - Graded papers
Doktorski rad
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Radić, Martina | Interakcije proteina p53 te karakterizacija stanica otpornih na ciljanu terapiju vemurafenibom u melanomu čovjeka / Herak Bosnar, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2021
urn.nsk.hr Deželjin, Martina | Utjecaj razine ekspresije gena nm23 na metastatski potencijal tumorskih stanica in vitro / Herak Bosnar, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2011
Peršec, Zoran | Uloga nm23-H1 u stanicama karcinoma prostate tijekom procesa lipidne peroksidacije / Herak Bosnar, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010
Bago, Ružica | Uloga gena nm23-H1 u adheziji stanica CAL 27 / Herak Bosnar, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2007
Herak Bosnar, Maja | Uloga gena nm23 u proliferaciji i diferencijaciji stanica in vitro / Pavelić, Jasminka (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2002
Diplomski rad (sveučilišni)
Bradić, Ivan | Interakcije proteina p53 s proteinima obitelji p53, NME i GLI / Herak Bosnar, Maja (mentor); Radić, Martina (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2019
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Bobić, Ivana | Ispitivanje fenotipa stanica humanog melanoma nakon tretmana vemurafenibom / Herak Bosnar, Maja (mentor); Radić, Martina (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2019
repozitorij.pmf.unizg.hr -
Ačkar, Lucija | Lokalizacija proteina NME6 i testiranje antitijela anti-NME6 / Herak Bosnar, Maja (mentor); Radić, Martina (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2018
urn.nsk.hr Barabaš, Ivana | Uspostava klonova stanica CAL 27 s trajno utišanim genom nm23-H2 / Herak Bosnar, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2011
Nakić, Nikolina | Uspostava stabilnih klonova stanica CAL 27 koji konstitutivno ispoljavaju mutirani oblik gena nm23-H2 / Herak Bosnar, Maja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2007
Other Publications
Ostalo
Levanat, Sonja ; Levačić Cvok, Mirela ; Musani, Vesna ; Car, Diana ; Osmak, Maja ; Herak Bosnar, Maja ; Slade, Neda ; Stojanović | Periodicum Biologorum HDIR-2 ''From Bench to Clinic''Second Meeting of the Croatian Association for Cancer research with International Participation / Vitale, Branko (ur.). Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2012. 87
Membership in professional associations / societies
Croatian Microscopy society-vice president -2020 today
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Member of the Oversight Commitee of Croatian Association for Cancer Research (branch of the EACR) – 2015-today Member of the Executive Committee of Croatian Society of Biochemistry and Molecular Biology – 2013-today Membership in scientific societies: Croatian Association for Cancer Research (branch of the EACR) 2009 - today Croatian Biological Society 2007.-today Croatian Society of Biochemistry and Molecular Biology, 1996.-today Hrvatsko Society of Human Genetics, 1994.-today European Urology Association, 1995-2000. |
Supervisor of doctoral thesis:
Ružica Bago: Uloga gena nm23-H1 u adheziji stanica CAL 27, 2007
Zoran Peršec: The role of nm23-H1 in prostate cancer cells during the process of lipid peroxidation, 2010
Martina Deželjin – The effect of Nm23 gene expression level on metstatic potential of tumor cells in vitro, 2011
Supervisor of diploma thesis:
Nikolina Nakić: Formation of stable CAL 27 clones constitutively expressing the mutated form of nm23-H2, 2007
Ivana Barabaš – Formation of CAL clones with permanently silenced nm23-H2 gene
Training:
Short-term fellowship of the French Republic 1999. Laboratory for intracellular signaling and oncogenesis, Curie Institut, France
Editor and author of several chapters in the textbook:
“Metode u molekularnoj biologiji” urednice: Andreja Ambriović Ristov, Anamaria Brozović, Branka Bruvo Mađarić, Helena Ćetković, Maja Herak Bosnar, Dubravka Hranilović, Silva Katušić Hećimović, Nevenka Meštrović Radan, Snježana Mihaljević, Neda Slade i Dušica Vujaklija, izdavač:Institut Ruđer Bošković, Zagreb, 2007.
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Main organizer, chair of the Organizing Committee and a member of the Scientific Committee of the 10th International Congress of the NDP Kinase/Nm23/awd Gene Family, October 9-13 2016, Dubrovnik, Croatia
Member of the organizing committee:
Member of the scientific committee:
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