Dr. Irena Dokli
Ruđer Bošković Institute
Bijenička 54
HR-10000 Zagreb
Education
- 2006.-2010. Ph. D. in Organic Chemistry, Faculty of Science, University of Zagreb.
- 2000.-2005. B. Sc. / M. Sc. in Chemistry, Faculty of Science, University of Zagreb.
Featured projects
Publications - book chapters
Original scientific paper
Hameršak, Zdenko ; Dokli, Irena ; Ivšić, Trpimir | Chapter 15:Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon–Heteroatom Bond-forming Reactions // Sustainable Catalysis : Without Metals or Other Endangered Elements, Part 2. | Cambridge: RSC Publishing Home, 2016. str. 44-81
Publications - journal articles
Original scientific paper
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Kolman, Robert Junior; Milčić, Nevena; Leščić Ašler, Ivana; Štefanić, Zoran; Švaco, Petra; Stepanić, Višnja; Brkljača, Zlatko; Dokli, Irena; Findrik Blažević, Zvjezdana; Majerić Elenkov, Maja | Biocatalytic synthesis of fluorine-containing chiral azido compounds in a two-phase system // Tetrahedron letters, 178 (2026), 155982, 6. doi: 10.1016/j.tetlet.2026.155982
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Ožegović, Antonija; Šimanović, Aleksandra; Dokli, Irena; Davidson, Patrick; Dozov, Ivan; Novak, Jurica; Knežević, Anamarija; Lesac, Andreja | Temperature-induced helix inversion in naphthyl-based cholesteric liquid crystals // Materials chemistry frontiers, 9 (2025), 19; 2900-2908. doi: 10.1039/d5qm00456j
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Ožegović, Antonija; Dokli, Irena; Knežević, Anamarija; Šegota, Suzana; Lesac, Andreja | Bent-shaped dimers with chiral spacer – unravelling the potential of the naphthyl mesogenic unit // Liquid crystals, 52 (2025), 1390-1400. doi: 10.1080/02678292.2024.2441355
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Mehić, Emina; Kolman, Robert Junior; Dokli, Irena; Majerić Elenkov, Maja | Biocatalytically Generated Library of Chiral Building Blocks Containing a Quaternary Stereocenter // Organic letters, 26 (2024), 49; 10430-10434. doi: 10.1021/acs.orglett.4c03399
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Barešić, Luka; Marijanović, Monika; Dokli, Irena; Margetić, Davor; Glasovac, Zoran | Cocatalytic Activity of the Furfuryl and Oxanorbornane-Substituted Guanidines in the Aldol Reaction Catalyzed by (S)-Proline // International journal of molecular sciences, 25 (2024), 10; 5570, 14. doi: 10.3390/ijms25105570
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Kolman, Robert Junior; Švaco, Petra; Majerić Elenkov, Maja; Dokli, Irena | Synthesis and HHDH‐Catalyzed Kinetic Resolution of Propargylic Epoxides // Advanced synthesis & catalysis, 366 (2024), 24; 5066-5072. doi: 10.1002/adsc.202400734
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Meyer, Claire; Sergan, Tatiana; Sergan, Vassili; Stoenescu, Daniel; Davidson, Patrick; Knežević, Anamarija; Dokli, Irena; Lesac, Andreja; Dozov, Ivan | Theoretical model for the Frank elastic moduli in the intercalated SmAb phase of bent-shaped dimers // Liquid crystals, 51 (2024), 6; 961-974. doi: 10.1080/02678292.2024.2306318
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Milčić, Nevena; Sudar, Martina; Dokli, Irena; Majerić Elenkov, Maja; Findrik Blažević, Zvjezdana | Halohydrin dehalogenase-catalysed synthesis of enantiopure fluorinated building blocks: bottlenecks found and explained by applying a reaction engineering approach // Reaction chemistry & engineering, 8 (2023), 3; 673-686. doi: 10.1039/D2RE00461E
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Meyer, Claire ; Davidson, Patrick ; Sergan, Tatiana ; Sergan, Vassili ; Stoenescu, Daniel ; Knežević, Anamarija ; Dokli, Irena ; Lesac, Andreja ; Dozov, Ivan | Nematic-like elastic coefficients of the SmAb phase // Liquid crystals, 50 (2023), 1; 157-173. doi: 10.1080/02678292.2022.2114026
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Meyer, Claire ; Davidson, Patrick ; Luckhurst, Geoffrey R. ; Dokli, Irena ; Knežević, Anamarija ; Lesac, Andreja ; Paterson, Daniel A. ; Walker, Rebecca ; Storey, John M. D. ; Imrie, Corrie T. et al. | Temperature Dependence of the Electroclinic Effect in the Twist-Bend Nematic Phase // Crystals, 13 (2023), 3; 465, 22. doi: 10.3390/cryst13030465
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Dokli, Irena ; Brkljača, Zlatko ; Švaco, Petra ; Tang, Lixia ; Stepanić, Višnja ; Majerić Elenkov, Maja | Biocatalytic approach to chiral fluoroaromatic scaffolds // Organic & biomolecular chemistry, 20 (2022), 9734-9741. doi: 10.1039/D2OB01955H
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Dokli, Irena ; Ožegović, Antonija ; Šimanović, Aleksandra ; Hromin, Matija ; Knežević, Anamarija ; Višnjevac, Aleksandar ; Lesac, Andreja | Enantioselective Synthesis of 3-Aryl-3- hydroxypropanoic Esters as Subunits for Chiral Liquid Crystals // Journal of organic chemistry, 87 (2022), 21; 14045-14057. doi: 10.1021/acs.joc.2c01662
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Mehić, Emina ; Hok, Lucija ; Wang, Qian ; Dokli, Irena ; Svetec Miklenić, Marina ; Findrik Blažević, Zvjezdana ; Tang, Lixia ; Vianello, Robert ; Majerić Elenkov, Maja | Expanding the scope of enantioselective halohydrin dehalogenases – group B // Advanced synthesis & catalysis, 364 (2022), 15; 2576-2588. doi: 10.1002/adsc.202200342
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Meyer, Claire ; Davidson, Patrick ; Constantin, Doru ; Sergan, Vassili ; Stoenescu, Daniel ; Knežević, Anamarija ; Dokli, Irena ; Lesac, Andreja ; Dozov, Ivan | Fréedericksz-Like Transition in a Biaxial Smectic- A Phase // Physical review. X, 11 (2021), 3; 031012, 25. doi: 10.1103/physrevx.11.031012
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Knežević, Anamarija ; Dokli, Irena ; Novak, Jurica ; Kontrec, Darko ; Lesac, Andreja | Fluorinated twist-bend nematogens: the role of intermolecular interaction // Liquid crystals, 48 (2021), 5; 756-766. doi: 10.1080/02678292.2020.1817585
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Dokli, Irena ; Pohl, Radek ; Klepetářová, Blanka ; Jahn, Ullrich | First total synthesis of ent-asperparaline C and assignment of the absolute configuration of asperparaline C // Chemical communications, 55 (2019), 27; 3931-3934. doi: 10.1039/C9CC00945K
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Buljan, Anđela ; Knežević, Anamarija ; Dokli, Irena ; Lesac, Andreja | Synthesis and Mesomorphic Properties of Novel Bent-shaped Naphthyl Diketones // Croatica chemica acta, 92 (2019), 2; 3541, 7. doi: 10.5562/cca3541
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Knežević, Anamarija ; Sapunar, Marin ; Buljan, Anđela ; Dokli, Irena ; Hameršak, Zdenko ; Kontrec, Darko ; Lesac, Andreja | Fine-tuning effect of p–p interactions on the stability of the NTB phase // Soft matter, 14 (2018), 8466-8474. doi: 10.1039/c8sm01569d
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Lesac, Andreja ; Baumeister, Ute ; Dokli, Irena ; Hameršak, Zdenko ; Ivšić, Trpimir ; Kontrec, Darko ; Viskić, Marko ; Knežević, Anamarija ; Mandle, Richard J. | Geometric aspects influencing N-NTB transition - implication of intramolecular torsion // Liquid crystals, 45 (2018), 7; 1101-1110. doi: 10.1080/02678292.2018.1453556
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Knežević, Anamarija ; Dokli, Irena ; Sapunar, Marin ; Šegota, Suzana ; Baumeister, Ute ; Lesac, Andreja | Induced smectic phase in binary mixture of twist- bend nematogens // Beilstein journal of nanotechnology, 9 (2018), 1297, 11. doi: 10.3762/bjnano.9.122
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Orehovec, Iva ; Glavač, Danijel ; Dokli, Irena ; Gredičak, Matija ; Piantanida, Ivo | Impact of the Supramolecular Organisation of Pyrene – Quinoline Conjugates on their Interaction with ds – DNA // Croatica chemica acta, 90 (2017), 4; 603-611. doi: 10.5562/cca3269
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Glavač, Danijel ; Zheng, Chao ; Dokli, Irena ; You, Shu-Li ; Gredičak, Matija | Chiral Brønsted Acid Catalyzed Enantioselective aza-Friedel–Crafts Reaction of Cyclic α-Diaryl N-Acyl Imines with Indoles // Journal of organic chemistry, 82 (2017), 16; 8752-8760. doi: 10.1021/acs.joc.7b01420
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Glavač, Danijel ; Dokli, Irena ; Gredičak, Matija | Synthesis of 3–aryl 3–hydroxyisoindolinones by the Addition of Grignard and Organolithium Reagents to Phthalimides // Current organic chemistry, 21 (2017), 14; 1335-1340. doi: 10.2174/1385272821666170222100150
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Ivšić, Trpimir ; Baumeister, Ute ; Dokli, Irena ; Mikleušević, Ana ; Lesac, Andreja | Sensitivity of the NTB Phase Formation to the Molecular Structure of Imino-linked Dimers // Liquid crystals, 44 (2017), 1; 93-105. doi: 10.1080/02678292.2016.1225832
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Suć, Josipa ; Dokli, Irena ; Gredičak, Matija | Chiral Brønsted Acid-Catalysed Enantioselective Synthesis of Isoindolinone-Derived N(acyl), S- Acetals // Chemical communications, 52 (2016), 2071-2074. doi: 10.1039/C5CC08813E
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Dokli, Irena ; Gredičak, Matija | Mechanochemical Ritter reaction : a rapid approach to functionalized amides at room temperature // European journal of organic chemistry, 2015 (2015), 12; 2727-2732. doi: 10.1002/ejoc.201500051
doionlinelibrary.wiley.com Ivšić, Trpimir ; Dokli, Irena ; Rimac, Ana ; Hameršak, Zdenko | Synthesis of GABOB and GABOB-based chiral units possessing distinct protecting groups // European journal of organic chemistry, 2014 (2014), 3; 631-638
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Dokli, Irena ; Navarini, Luciano ; Hameršak, Zdenko | Syntheses of 3-, 4- and 5-O-Feruloylquinic Acids // Tetrahedron: asymmetry, 24 (2013), 13/14; 785-790. doi: 10.1016/j.tetasy.2013.06.002
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Majerić Elenkov,Maja; Primožič, Ines; Hrenar, Tomica; Smolko, Ana; Dokli, Irena; Salopek-Sondi,Branka; Tang, Lixia | Catalytic activity of halohydrin dehalogenases towards spiroepoxides // Organic & biomolecular chemistry, 10 (2012), 5063-5072. doi: 10.1039/C2OB25470K
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Knežević, Anamarija ; Landek, Goran ; Dokli, Irena ; Vinković, Vladimir | An efficient enzymatic approach to (S)-1-aryl-allylamines // Tetrahedron: asymmetry, 22 (2011), 9; 936-941. doi: 10.1016/j.tetasy.2011.06.004
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Dokli, Irena ; Matanović, Ivana ; Hameršak, Zdenko | Sulfur Ylide Promoted Synthesis of N-Protected Aziridines : A Combined Experimental and Computational Approach // Chemistry : a European journal, 16 (2010), 38; 11744-11752. doi: 10.1002/chem.201001436
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Horvat, Štefica ; Hameršak, Zdenko ; Stipetić, Irena ; Jolas, Thierry | Synthesis, Characterization and in Vitro Pharmacology of Novel Pregabalin Derivatives // European journal of medicinal chemistry, 45 (2010), 4; 1447-1452. doi: 10.1016/j.ejmech.2009.12.049
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Pandurić, Vlatko ; Tarle, Zrinka ; Hameršak, Zdenko ; Stipetić, Irena ; Matošević, Danijela ; Negovetić-Mandić, Višnja ; Prskalo, Katica | Detection of HEMA in self-etching adhesive systems with high performance liquid chromatography // Journal of molecular structure, 924-926 (2009), SI; 358-360. doi: 10.1016/j.molstruc.2008.12.024
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Stipetić, Irena ; Roje, Marin ; Hameršak, Zdenko | Highly Enantioselective Aziridination of N-Protected Imines : Comparison of the Phosphazene EtP2 and Sodium Hydride as Bases // Synlett, 2008 (2008), 20; 3149-3152. doi: 10.1055/s-0028-1087367
doiwww.thieme-connect.de Hameršak, Zdenko ; Stipetić, Irena ; Avdagić, Amir | An efficient synthesis of (S)-3-Aminomethyl-5-methylhexanoic acid (Pregabalin) via quinine-mediated desymmetrization of cyclic anhydride // Tetrahedron: asymmetry, 18 (2007), 12; 1481-1485
Short communication
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Dokli, Irena; Milčić, Nevena; Marin, Petra; Svetec Miklenić, Marina; Sudar, Martina; Tang, Lixia; Findrik Blažević, Zvjezdana; Majerić Elenkov, Maja | Halohydrin dehalogenase-catalysed synthesis of fluorinated aromatic chiral building blocks // Catalysis communications, 152 (2021), 106285, 5. doi: 10.1016/j.catcom.2021.106285
doiwww.sciencedirect.comfulir.irb.hrdx.doi.org
Review article (scientific)
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Glavač, Danijel; Majerić Elenkov, Maja; Dokli, Irena | Halohydrin dehalogenases in organic synthesis // Tetrahedron Chem, 19 (2026), 100169--. doi: 10.1016/j.tchem.2026.100169
doiwww.tetrahedron-chem.com