A recent study published in Biomedicines offers compelling insights into how resveratrol, a natural polyphenol, and its primary metabolite trans-resveratrol-3-O-glucuronide, may serve as allosteric modulators of monoamine oxidase A (MAO-A)—a key enzyme involved in regulating mood-related neurotransmitters.

Solving large-scale sparse eigenproblems in Density Functional Theory (DFT) simulations is a critical bottleneck, especially for computationally demanding biomolecular systems.

The Vera C. Rubin Observatory is a new NSF/DOE-funded facility on Cerro Pachón, Chile. It houses the 8.4m Simonyi Survey Telescope and the 3.2 Gigapixel LSSTCam camera. The Observatory is in the final stages of construction, and has just finished
its first phase of commissioning.Speaker will describe the Rubin system, provide an update on its construction and commissioning efforts, and discuss the areas where we will use HPC and  AI.

The World Science Forum (WSF) was held in Budapest from November 20 to 23, 2024, bringing together over 1,200 participants from 122 countries. The main theme of the forum was "The Science-Policy Interface in Times of Global Transformations," with a focus on strengthening trust in science and improving collaboration between the scientific community and policymakers to ensure sustainable development and a prosperous future for humanity.

We’re excited to invite you to the EBSI-NE Forum, a unique event dedicated to exploring Distributed Ledger Technology (DLT) and its pivotal role in enhancing the European Blockchain Services Infrastructure (EBSI).

We are delighted to invite researchers, academics, and professionals to submit their original research papers to the MDPI Journal for our upcoming Special Issue: "Parallel, Distributed Computing, and Computational Mathematics."

Prostate cancer ranks among the most common cancers affecting men worldwide. Despite significant advancements in available therapies, a critical challenge persists: preventing the disease from progressing to its most dangerous and treatment-resistant stage. Addressing this issue, a multidisciplinary team of researchers and doctors, led by scientists from the Ruđer Bošković Institute (IRB), has made a groundbreaking discovery. They have developed an innovative computational tool named Vini, designed to predict the most effective drug combinations for treating castration-resistant prostate cancer. The ultimate aim of this tool is to halt the progression of the disease to its deadly, therapy-resistant phase. This pioneering research was recently published in the prestigious journal Scientific Reports.