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Dr. Tvrtko Smital

Head of laboratory
Head of division
+385 1 456 1088
Internal phone number
Academic title
Assistant Professor
Rudjer Boskovic Institute
Division for Marine and Environmental Research
Laboratory for Molecular Ecotoxicology
Bijenicka 54, 10000 Zagreb
Curriculum vitae


-       UniversityofZagreb, Faculty of Science; B. Sc., 1994, Biology-Ecology

-       UniversityofZagreb, Faculty of Science; Mr. Sc., 1998, Biology-Toxicology

-       UniversityofZagreb, Faculty of Science; PhD, 1999, Biology-Ecotoxicology

Research Areas

Specific research interests



-        Ecotoxicological characterization of biologically active substances and complex marine environment samples – Project within the Centre for Excellence for Science and Technology – Integration of Mediterranean Region (ZCI-STIM; (2017-2021) – project funded by the European Union through the European Regional Development Fund – the Operational Programme Competitiveness and Cohesion 2014-2020 (KK.; principal investigator.

-      Understanding the (eco)toxicological role of selected SLC and MATE transport proteins in zebrafish (Danio rerio) using functional genomics tools, (2020-2023) – Croatian Science Foundation research project – principal investigator;


Educational Activities/Lecturing

-        M. Erk, T. Smital – Course Biological effects of metals and organic pollutants on marine organisms; Postgraduate study, Oceanology, Faculty of Science, University of Zagreb;

-        T. Smital – Course Ecotoxicology; Postgraduate study "Protection of Nature and the Environment", University of Osijek;

-        G. Klobučar, M. Pavlica, V. Garaj-Vrhovac, T. Smital – Course Biomarkers in Biomonitoring of Environmental Contamination; Postgraduate study in Biology, Faculty of Science, University of Zagreb.


Books and book chapters

Book chapters

Journal articles

Scientific and review papers

Conference proceedings papers

Scientific conference proceedings papers


  • Kurelec, B., Smital, T. & Pivčević, B. (1996) Exstract from marine tropic alga introduced into Mediterranean, Caulerpa taxifolia, reverts multidrug resistance (MDR) in tumor cell culture.


Doctoral dissertation

  • Smital, T. (1999) 'Activity of the multixenobiotic resistance mechanism in aquatic organisms as an indicator of the environmental quality', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.

Master thesis

  • Smital, T. (1998) 'In vivo determination of the concentration of inhibitors of the multixenobiotic resistance mechanism (MXR) in river waters', magistarski rad, Prirodoslovno-matematički fakultet, Zagreb.

Membership in professional associations / societies

Member of Croatian Biological Society, Croatian Toxicological Society and International Society of Ecotoxicology and Environmental Safety (SECOTOX).

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