-       UniversityofZagreb, Faculty of Science; B. Sc., 1994, Biology-Ecology

-       UniversityofZagreb, Faculty of Science; Mr. Sc., 1998, Biology-Toxicology

-       UniversityofZagreb, Faculty of Science; PhD, 1999, Biology-Ecotoxicology

Ongoing:

-        Ecotoxicological characterization of biologically active substances and complex marine environment samples – Project within the Centre for Excellence for Science and Technology – Integration of Mediterranean Region (ZCI-STIM;  https://stim.unist.hr/hr/) (2017-2021) – project funded by the European Union through the European Regional Development Fund – the Operational Programme Competitiveness and Cohesion 2014-2020 (KK.01.1.1.01); principal investigator.

-      Understanding the (eco)toxicological role of selected SLC and MATE transport proteins in zebrafish (Danio rerio) using functional genomics tools, (2020-2023) – Croatian Science Foundation research project – principal investigator;

• Assessment of efficacy and toxicity of biologically active substances - BioMolTox

  01.01.2024 - 31.12.2027 | 763,985.00 EUR

  CroRISIRB

• STIM-REI 2.0 (Research (R), Innovation (I) and Education (E)) - STIM-REI 2.0

  01.12.2023 - 01.12.2026 | 1,416,207.02 EUR

  CroRISIRB

• Razumijevanje (eko)toksikološke uloge odabranih SLC i MATE transportnih proteina zebrice (Danio rerio) korištenjem metoda funkcionalne genomike - DANIOTRANS

  23.03.2021 - 22.09.2025 | 0.00 EUR

  CroRISIRB

• Understanding the (eco)toxicological role of selected SLC and MATE transport proteins in zebrafish (Danio rerio) using functional genomics tools - DANIOTRANS

  01.03.2020 - 29.02.2024 | 125,688.50 EUR

  CroRISIRB

• STIM-REI (eng. Research, Education, Innovation) - STIM-REI

  15.10.2017 - 30.11.2023 | 37,999,788.07 HRK

  CroRISIRB

• Identification and functional characterization of (eco)toxicologically relevant polyspecific membrane transpord proteins in zebrafish (Danio rerio) - TRANS-ZEBRATOX

  01.10.2014 - 30.04.2018 | 108,979.67 EUR

  CroRISIRB

• Identification and characterization of cyanobacterial toxins based on their interaction with basic cellular detoxification systems in zebrafish (Danio rerio) and Daphnia magna

  01.04.2014 - 30.11.2017 | 75,000.00 CHF

  CroRISIRB

• Assessment of hazardous chemical contamination in the Sava River basin

  01.10.2007 - 01.10.2010 | 210,000.00 EUR

  CroRISIRB

• Ecotoxicological relevance of the ABC transport proteins in aquatic organisms

  01.01.2007 - 01.01.2009 | 0.00 EUR

  CroRISIRB

• Sava River Basin: Sustainable Use, Management and Protection of Resources - SARIB

  01.08.2004 - 31.07.2007 | 1,981,125.00 EUR

  CroRISIRB

Educational Activities/Lecturing

-        M. Erk, T. Smital – Course Biological effects of metals and organic pollutants on marine organisms; Postgraduate study, Oceanology, Faculty of Science, University of Zagreb;

-        T. Smital – Course Ecotoxicology; Postgraduate study "Protection of Nature and the Environment", University of Osijek;

-        G. Klobučar, M. Pavlica, V. Garaj-Vrhovac, T. Smital – Course Biomarkers in Biomonitoring of Environmental Contamination; Postgraduate study in Biology, Faculty of Science, University of Zagreb.

Science Citation Index Publications

1. Smital T, Pivčević B. and Kurelec B. (1996) Reversal of multidrug resistance by extract from the marine alga Caulerpa taxifolia. Period. Biol. 98: 165-171.
2. Smital T. and Kurelec B. (1997) Inhibitors of the multixenobiotic resistance mechanism in natural waters: In vivo demonstration of their effects. Environ. Toxicol. Chem. 16: 2164-2170.
3. Kurelec B., Smital T., Britvić S., Pivčević B., Krča S., Jelaska D., Balen S., Sauerborn R. and Mustajbegović S. (1997) Multixenobiotic defence mechanism in aquatic organisms. Period. Biol. 99: 319-328.
4. Smital. T. and Kurelec B. (1998) The chemosensitizers of multixenobiotic resistance mechanism in aquatic invertebrates; A new class of pollutants. Mutat. Res.-Fund. Mol. M. 399: 45-53.
5. Kurelec B., Britvić S. and Smital T. (1998) Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment. Mar. Environ. Res. 46: 415-419.
6. Smital T. and Kurelec B. (1998) The activity of multixenobiotic resistance mechanism determined by rhodamine B - efflux method as a biomarker of exposure. Mar. Environ. Res. 46: 443-447.
7. Osmak M., Brozović A., Ambriović-Ristov A., Hadžija M., Pivčević B., and Smital T. (1998) Inhibition of apoptosis is the cause of resistance to doxorubicin in human breast adenocarcinoma cells. Neoplasma 45: 223-230.
8. Kurelec, B., Smital, T., Pivčević, B., Eufemia, N. and Epel, D. (2000) Multixenobiotic resistance, P-glycoprotein, and chemosensitizers. Ecotoxicology 9: 307-327.
9. Smital, T., Sauerborn, R., Pivčević, B., Krča, S. and Kurelec, B. (2000) Interspecies differences in P-glycoprotein mediated activity of multixenobiotic resistance mechanism in several marine and freshwater invertebrates, Comp. Biochem. Physiol C., 126: 175-186.
10. Ramljak, S., Hackenberger, B.K., Smital, T. and Britvić, S. (2000) Evaluation of the genotoxic and cytochrome P450 monooxygenase-inhibitory potential of dicuran on procariotic and eucaryotic test systems, J.  Environ. Sci. Health B. B35: 751-770.
11. Smital, T. and Sauerborn, R. (2002) Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio. Mar. Environ. Res. 54: 449-453.
12. Smital, T., Sauerborn, R. and Hackenberger, B.K. (2003) Inducibility of the P-glycoprotein transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha. Aquat. Toxicol. 65: 443-465.
13. Sauerborn, R., Stupin Polancec, D., Zaja, R. and Smital, T. (2004) Identification of the multidrug resistance-associated protein (MRP) related gene in the red mullet (Mullus barbatus). Mar. Environ. Res., 58: 199-204.
14. Smital, T., Luckenbach, T., Sauerborn, R., Hamdoun, A.M., Vega, R.L. and Epel, D. (2004) Emerging contaminants – pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms. Mut. Res.-Fund. Mol. M., 552: 101-117.
15. Žaja, R., Klobučar, G.I.V., Sauerborn Klobučar, R., Hackenberger, B., and Smital, T. (2006) Haemolymph as compartment for efficient and non-destructive determination of Pgp mediated MXR activity in bivalves. Comp. Biochem. Physiol. C., 143: 103-112.
16. Žaja, R., Sauerborn Klobučar R. and Smital, T. (2007) Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line. Aquat. Toxicol., 81: 365-376.
17. Krča, S., Žaja, R., Čalić, V., Terzić, S., Grubešić, M.S., Ahel, M. and Smital, T. (2007) Hepatic biomarker responses to organic contaminants in feral chub (Leuciscus cephalus) – laboratory characterization and field study in the Sava River, Croatia. Environ. Toxicol. Chem., 26: 2620-2633.
18. Žaja, R., Caminada, D., Lončar, J., Fent, K. and Smital, T. (2008) Development and characterization of P-glycoprotein 1 (Pgp1; ABCB1) mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line. Toxicol. Appl. Pharmacol., 227: 207-218.
19. Žaja, R., Munić, V., and Smital, T. (2008) Cloning and mRNA expression analysis of an ABCG2 (BCRP) efflux transporter in rainbow trout (Oncorhynchus mykiss) liver and primary hepatocytes. Mar. Environ. Res., 66: 77-79.
20. Källqvist, T., Milačič, R., Smital, T., Thomas, K.V., Vranes, S. and Tollefsen, K-E. (2008) Chronic toxicity of the Sava River (SE Europe) sediments and river water to the algae Pseudokirchneriella subcapitata. Water Res., 42: 2146-2156.
21. Epel, D., Stevenson, C.N., MacManus-Spencer, L.A., Luckenbach, T., Hamdoun, A., and Smital, T. (2008) Efflux transporters: newly appreciated roles in protection against pollutants. Environ. Sci. Tech., 42: 3914-3920.
22. Traven, L., Žaja, R., Lončar, J., Smital, T. and Mićović, V. (2008) CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – In vitro evaluation using the PLHC-1 fish hepatoma cell line. Toxicol. In Vitro, 22: 1648-1656.
23. Caminada, D., Žaja, R., Smital, T. and Fent, K. (2008) Human pharmaceuticals modulate P-gp1 (ABCB1) transport activity in the fish cell line PLHC-1. Aquat. Toxicol., 90: 214–222.
24. Žaja, R., Munić, V., Sauerborn Klobučar, R., Ambriović-Ristov, A., Smital, T. (2008) Cloning and functional characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol. 90: 322-332.
25. Bošnjak, I., Heim, W., Smital, T., Epel, D., Coale, K., Franekić-Čolić, J., Hamdoun, A. (2009) Multidrug resistance associated protein transport activity mediates differences in accumulation and toxicity of inorganic and organic mercury in sea urchin embryos. Environ. Sci. Tech. 43: 8374-8380.
26. Lončar, J., Popović, M., Žaja, R., Smital, T. (2010) Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Physiol. C. 151: 209-215.
27. Popović, M., Žaja, R., Lončar, J., Smital, T. (2010) A novel ABC transporter: the first insight into zebrafish (Danio rerio) Abch1. Mar. Environ. Res. 69: S11-S13.
28. Popović, M., Žaja, R., Smital, T. (2010) Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): phylogenetic analysis and tissue distribution. Comp. Biochem. Physiol. A 155: 327-335.  
29. Sauerborn Klobučar, R., Zaja, R., Franjević, D., Brozović, A., Smital, T. (2010) Presence of Ecotoxicologically Relevant Pgp- and MRP- Transcripts and Proteins in Cyprinid Fish. Arh. Hig. Rada Toksikol. 61: 175-181.
30. Bošnjak, I., Šegvić, T., Smital, T., Franekić, J., Mladineo, I. (2011) Sea Urchin Embryotoxicity Test for Environmental Contaminants—Potential Role of the MRP Proteins. Water Air Soil Poll. 217: 627-636.
31. Fischer, S., Loncar, J., Zaja, R., Schnelle, S., Schirmer, K., Smital, T., Luckenbach, T. (2011) Constitutive mRNAexpression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 101: 438-446.
32. Smital, T., Terzic, S., Zaja, R., Senta, I., Pivcevic, B., Popovic, M., Mikac, I., Tollefsen, K.E., Thomas, K.V., Ahel, M. (2011) Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays. Ecotoxicol. Environ. Saf. 74: 844-851.
33. Zaja, R., Loncar, J., Popovic, M., Smital, T. (2011) First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line. Aquat. Toxicol. 103: 53-62.
34. Reifferscheid, G., Maes, H., Allner, B., Badurova, J., Belkin, S., Blum, K., Brauer, F., Bressling, J., Domeneghetti, S., Elad, T., Flückiger-Isler, S., Grummt, H.J., Guertler, R., Hecht, A., Heringa, M., Hollert, H., Huber, S., Kramer, M., Magdeburg, A., Ratte, T., Sauerborn-Klobucar, R., Sokolowski, A., Soldan, P., Smital, T., Stalter, D., Venier, P., Ziemann, C., Zipperle, J., Buchinger, S. (2012) International round-robin study on the Ames fluctuation test. Environ. Mol. Mutag. 53: 185-197.
35. Della Torre, C., Zaja, R., Loncar, J., Smital, T., Focardi, S., Corsi, I. (2012) Interaction of ABC transport proteins with toxic metals at the level of gene and transport activity in the PLHC-1 fish cell line. Chem. Biol. Interac. 198: 9-17.
36. Smital, T., Terzić, S., Lončar, J., Senta, I., Zaja, R., Popović, M., Mikac, I., Tollefsen, K-E., Thomas, K.V., Ahel, M. (2013) Prioritisation of organic contaminants in a river basin using chemical analyses and bioassays. Environ. Sci. Poll. Res. 20: 1384-1395.
37. Zaja, R., Terzić, S., Senta, I., Lončar, J., Popović, M., Ahel, M., Smital, T. (2013) Identification of P-glycoprotein (P-gp, Abcb1) inhibitors in contaminated freshwater sediments. Environ. Sci. Tech. 47: 4813-4821.
38. Traven, L., Mićović, V., Vukić Lušić, D., Smital, T. (2013) The responses of the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity in sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a polluted site: implications for their use in environmental risk assessment. Environ Monit Assess. 185: 9009-9018.
39. Bošnjak, I., Zaja, R., Klobučar, R.S., Sver, L., Franekić, J., Smital, T. (2013) Identification of ABC Transporter Genes in Gonad Tissue of Two Mediterranean Sea Urchin Species: Black, Arbacia lixula L., and Rocky, Paracentrotus lividus L. Bull. Environ. Contam. Toxicol. 91: 415-419. 
40. Popovic, M., Zaja, R., Fent, K., Smital, T. (2013) Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel Organic anion transporting polypeptide. J. Biol. Chem. 288: 33894–33911.
41. Ferreira, M., Santos, P., Rey-Salgueiro, L., Zaja, R., Reis-Henriques, M.A., Smital, T. (2014) The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European seabass (Dicentrarchus labrax) primary hepatocytes. Chemosphere 100: 152-159.
42. Popovic, M., Zaja, R., Fent, K., Smital, T. (2014) Interaction of environmental contaminants with zebrafish uptake transporter Oatp1d1 (Slco1d1). Toxicol. Appl. Pharmacol. 280: 149-158.
43. Glisic, B., Mihaljevic, I., Popovic, M., Zaja, R., Loncar, J., Fent, K., Kovacevic, R., Smital, T. (2015) Characterization of glutathione-S-transferases in zebrafish (Danio rerio). Aquat. Toxicol. 158: 50-62.
44. Lončar, J., Popović, M., Krznar, P., Zaja, R., Smital, T. (2016) The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio). Sci. Rep. 6: 28937, DOI: 10.1038/srep28937.
45. Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2016) Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio). BMC Genomics, 17: 626, DOI 10.1186/s12864-016-2981-y.
46. Zaja, R., Popović, M., Lončar, J., Smital, T. (2016) Functional characterization of rainbow trout (Oncorhynchus mykiss) Abcg2a (Bcrp) transporter. Comp. Biochem. Physiol. C, 190: 15-23.
47. Mihaljević, I., Popović, M., Žaja, R., Maraković, N., Šinko, G., Smital, T. (2017) Interaction between the zebrafish (Danio rerio) organic cation transporter 1 (Oct1) and endo- and xenobiotics. Aquat. Toxicol. 187: 18-28.
48. Marić, P., Ahel, M., Senta, I., Terzić, S., Mikac, I, Žuljević, A., Smital, T. (2017) Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia. Chemosphere 174: 643-654.
49. Dragojević, J., Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2017) In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e. Toxicol In Vitro 46: 246-256.
50. Terzić, S., Udikovic-Kolić, N., Jurina, T., Krizman-Matašica, I., Senta, I., Mihaljević, I., Lončar, J., Smital, T., Ahel, M. (2018) Biotransformation of macrolide antibiotics using enriched activated sludge culture: Kinetics, transformation routes and ecotoxicological evaluation. J. Haz. Mat. 349: 143-152.
51. Lončar, J., Smital, T. (2018) Interaction of environmental contaminants with zebrafish (Danio rerio) multidrug and toxin extrusion protein 7 (Mate7/Slc47a7). Aquat. Toxicol. 205: 193-203.
52. Dean Karaica, Davorka Breljak, Jovica Lončar, Mila Lovrić, Vedran Micek, Ivana Vrhovac Madunić, Hrvoje Brzica, Carol M. Herak-Kramberger, Jana Ivković Dupor, Marija Ljubojević, Tvrtko Smital, Željka Vogrinc, Gerhard Burckhardt, Birgitta C. Burckhardt, Ivan Sabolić (2018) Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys. Arh. Hig. Rada Toksikol. 69: 286-303.
53. Kostanjevecki, P., Petric, I., Loncar, J., Smital, T., Ahel, M., Terzic, S. (2019) Biodegradation study of methadone by adapted activated sludge: elimination kinetics, transformation products and ecotoxicological evaluation. Chemosphere 214: 719-728.
54. Bašica, B., Mihaljević, I., Maraković, N., Kovačević, R., Smital, T. (2019) Molecular characterization of zebrafish Gstr1, the only member of teleost-specific glutathione S- transferase class. Aquat. Toxicol. 208: 196-207.
55. Kostanjevecki, P., Petric, I., Loncar, J., Smital, T., Ahel, M., Terzic, S. (2019) Aerobic biodegradation of tramadol by pre-adapted activated sludge culture: Cometabolic transformations and bacterial community changes during enrichment. Sci. Total. Environ. 687: 858-866.
56. Dragojević, J., Mihaljević, I., Popović, M., Smital, T. (2019) Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds. Comp. Biochem. Physiol. B 236: 110309

Original scientific paper

• Smital, Tvrtko ; Ahel, Marijan | Ecotoxicological characterization of the Sava River – biomarker responses and biological assays // The Sava River. | Berlin : Heidelberg: Springer, 2015. str. 177-200

  link.springer.com

• Smital, Tvrtko | Acute and Chronic Effects of Emerging Contaminants // Emerging Contaminants from Industrial and Municipal Waste - Occurrence, Analysis and Effects. | Berlin: Springer, 2008. str. 154-193 . doi: 10.1007/978-3-540-74795-6_3

  doilink.springer.comdoi.org

• Epel, David ; Smital, Tvrtko | Multidrug-multixenobiotic transporters and their significance with respect to environmental levels of pharmaceuticals and personal care products // Pharmaceuticals and personal care products in the environment - scientific and regulatory issues. | Washington (MD): American Chemical Society (ACS) ; Oxford University Press, 2001. str. 244-263-x

Original scientific paper

• Vujica, Lana; Dragojević, Jelena; Lončar, Jovica; Otten, Cecile; Kutnjak, Marin; Babić, Sanja; Mihaljevic, Ivan; Smital, Tvrtko | Differential toxicity of perfluorooctane sulfonate (PFOS) in wild-type and Oatp1d1 mutant zebrafish larvae // Chemico-biological interactions, 428 (2026), 111955, 12. doi: 10.1016/j.cbi.2026.111955

  doiwww.sciencedirect.com

• Lončar, Jovica; Žaja, Roko; Mihaljević, Ivan; Dragojević, Jelena; Vujica, Lana; Kutnjak, Marin; Otten, Cecile; Smital, Tvrtko | Zebrafish Abcg2a mutant line as an in vivo model for evaluation of the interaction of Abcg2a with drugs and contaminants // Aquatic toxicology, 291 (2026), 107709, 11. doi: 10.1016/j.aquatox.2026.107709

  doiwww.sciencedirect.com

• Bakija Alempijević, Saranda; Strmečki, Slađana; Mihaljević, Ivan; Frka, Sanja; Dragojević, Jelena; Jakovljević, Ivana; Smital, Tvrtko | Ecotoxicity of Nitrated Monoaromatic Hydrocarbons in Aquatic Systems: Emerging Risks from Atmospheric Deposition of Biomass Burning and Anthropogenic Aerosols // Toxics, 13 (2025), 12; 1037, 22. doi: 10.3390/toxics13121037

  doifulir.irb.hrwww.mdpi.com

• Ivanković, Klaudija; Krizman-Matasić, Ivona; Dragojević, Jelena; Mihaljević, Ivan; Smital, Tvrtko; Ahel, Marijan; Terzić, Senka | Uptake/depuration kinetics, bioaccumulation potential and metabolic transformation of a complex pharmaceutical mixture in zebrafish (Danio rerio) // Journal of hazardous materials, 470 (2024), 134144, 12. doi: 10.1016/j.jhazmat.2024.134144

  doiwww.sciencedirect.comfulir.irb.hr

• Vujica, Lana; Mihaljević, Ivan; Dragojević, Jelena; Lončar, Jovica; Karaica, Dean; Dananić, Ana; Bošnjak, Arvena; Smital, Tvrtko | Functional knockout of the Oatp1d1 membrane transporter affects toxicity of diclofenac in zebrafish embryos // Aquatic toxicology, 273 (2024), 107031, 20. doi: 10.1016/j.aquatox.2024.107031

  doilinkinghub.elsevier.comfulir.irb.hr

• Vujica, Lana; Lončar, Jovica; Mišić, Lana; Lučić, Bono; Radman, Katarina; Mihaljević, Ivan; Bertoša, Branimir; Mesarić, Josip; Horvat, Marina; Smital, Tvrtko | Environmental contaminants modulate transport activity of zebrafish (Danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a2.1) // Science of the total environment, 901 (2023), 165956, 9. doi: 10.1016/j.scitotenv.2023.165956

  doiwww.sciencedirect.com

• Karaica, Dean; Mihaljević, Ivan; Vujica, Lana; Bošnjak, Arvena; Dragojević, Jelena; Otten, Cecile; Babić, Nency; Lončar, Jovica; Smital, Tvrtko | Stage-dependent localization of F-actin and Na+/K+-ATPase in zebrafish embryos detected using optimized cryosectioning immunostaining protocol // Microscopy research and technique, 86 (2022), 3; 294-310. doi: 10.1002/jemt.24270

  doianalyticalsciencejournals.onlinelibrary.wiley.com

• Frleta, Roberta ; Popović, Marijana ; Smital, Tvrtko ; Šimat, Vida | Comparison of Growth and Chemical Profile of Diatom Skeletonema grevillei in Bioreactor and Incubation-Shaking Cabinet in Two Growth Phases // Marine drugs, 20 (2022), 11; 697, 16. doi: 10.3390/md20110697

  doifulir.irb.hrwww.mdpi.com

• Marić, Petra; Ahel, Marijan; Maraković, Nikola; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter // Chemosphere, 283 (2021), 131155, 12. doi: 10.1016/j.chemosphere.2021.131155

  doiwww.sciencedirect.comfulir.irb.hr

• Dragojević, Jelena ; Marakovic, Nikola ; Popović, Marta ; Smital, Tvrtko | Zebrafish (Danio rerio) Oatp2b1 as a functional ortholog of the human OATP2B1 transporter // Fish physiology and biochemistry, 47 (2021), 6; 1837-1849. doi: 10.1007/s10695-021-01015-7

  doiwww.scopus.com

• Dragojević, Jelena ; Marić, Petra ; Lončar, Jovica ; Popović, Marta ; Mihaljević, Ivan ; Smital, Tvrtko | Environmental contaminants modulate transport activity of zebrafish organic anion transporters Oat1 and Oat3 // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 231 (2020), 108742, 8. doi: 10.1016/j.cbpc.2020.108742

  doiwww.sciencedirect.comdoi.org

• Mihaljević, Ivan ; Bašica, Branka ; Maraković, Nikola ; Kovačević, Radmila ; Smital, Tvrtko | Interaction of organotin compounds with three major glutathione S-transferases in zebrafish // Toxicology in vitro, 62 (2020), 104713, 9. doi: 10.1016/j.tiv.2019.104713

  doiwww.sciencedirect.comdoi.org

• Marić, Petra ; Ahel, Marijan ; Babić, Olivera ; Simeunović, Jelica ; Smital, Tvrtko | Ecotoxicological profiling of selected cyanobacterial strains using multi-endpoint effect-directed analysis // Ecotoxicology, 2020 (2020), s10646-020-02201-8, 16. doi: 10.1007/s10646-020-02201-8

  doidoi.orglink.springer.comlink.springer.com

• Kostanjevečki, Petra ; Sviličić Petrić, Ines ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Biodegradation study of methadone by adapted activated sludge: Elimination kinetics, transformation products and ecotoxicological evaluation // Chemosphere, 214 (2019), 719-728. doi: 10.1016/j.chemosphere.2018.09.153

  doiwww.sciencedirect.comdoi.org

• Bašica, Branka ; Mihaljević, Ivan ; Maraković, Nikola ; Kovačević, Radmila ; Smital, Tvrtko | Molecular characterization of zebrafish Gstr1, the only member of teleost-specific glutathione S- transferase class // Aquatic toxicology, 208 (2019), 196-207. doi: 10.1016/j.aquatox.2019.01.005

  doiwww.sciencedirect.com

• Kostanjevečki, Petra ; Petrić, Ines ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Aerobic biodegradation of tramadol by pre- adapted activated sludge culture: Cometabolic transformations and bacterial community changes during enrichment // Science of the total environment, 687 (2019), 858-866. doi: 10.1016/j.scitotenv.2019.06.118

  doiwww.sciencedirect.comdoi.org

• Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Smital, Tvrtko | Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds // Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 236 (2019), 110309, 11. doi: 10.1016/j.cbpb.2019.110309

  doiwww.sciencedirect.comdoi.org

• Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Lovrić, Mila ; Micek, Vedran ; Vrhovac Madunić, Ivana ; Brzica, Hrvoje ; Herak-Kramberger, Carol Mirna ; Ivković Dupor, Jana ; Ljubojević, Marija et al. | Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys // Arhiv za higijenu rada i toksikologiju, 69 (2018), 4; 286-303. doi: 10.2478/aiht-2018-69-3157

  doihrcak.srce.hr

• Terzić, Senka ; Udiković-Kolić, Nikolina ; Jurina, Tamara ; Krizman-Matasić, Ivona ; Senta, Ivan ; Mihaljević, Ivan ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan | Biotransformation of macrolide antibiotics using enriched activated sludge culture: Kinetics, transformation routes and ecotoxicological evaluation // Journal of hazardous materials, 349 (2018), 143-152. doi: 10.1016/j.jhazmat.2018.01.055

  doiwww.sciencedirect.com

• Lončar, Jovica ; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish multidrug and toxin extrusion protein 7 (Mate7/Slc47a7) // Aquatic toxicology, 205 (2018), 193-203. doi: 10.1016/j.aquatox.2018.10.016

  doidoi.org

• Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Šinko, Goran ; Smital, Tvrtko | Interaction between zebrafish Oct1 and endo- and xenobiotics // Aquatic toxicology, 187 (2017), 18-28. doi: 10.1016/j.aquatox.2017.03.012

  doiwww.sciencedirect.comdx.doi.org

• Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e // Toxicology in vitro, 46 (2017), 246-256. doi: 10.1016/j.tiv.2017.09.026

  doiwww.sciencedirect.com

• Marić, Petra ; Ahel, Marijan ; Senta, Ivan ; Terzić, Senka ; Mikac, Iva ; Žuljević, Ante ; Smital, Tvrtko | Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia // Chemosphere, 174 (2017), 643-654. doi: 10.1016/j.chemosphere.2017.02.007

  doiwww.sciencedirect.com

• Žaja, Roko ; Popović, Marta ; Lončar, Jovica ; Smital, Tvrtko | Functional characterization of rainbow trout (Oncorhynchus mykiss) Abcg2a (Bcrp) transporter // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 190 (2016), 15-23. doi: 10.1016/j.cbpc.2016.07.005

  doiwww.sciencedirect.com

• Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio) // Bmc genomics, 17 (2016), 626-1-626-13. doi: 10.1186/s12864-016-2981-y

  doibmcgenomics.biomedcentral.com

• Lončar, Jovica ; Popović, Marta ; Krznar, Petra ; Žaja, Roko ; Smital, Tvrtko | The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio) // Scientific reports, 6 (2016), 28937, 15. doi: 10.1038/srep28937

  doiwww.nature.comwww.nature.com

• Glišić, Branka ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Fent, Karl ; Kovačević, Radmila ; Smital, Tvrtko | Characterization of Glutathione-S-transferases in zebrafish (Danio rerio) // Aquatic toxicology, 158 (2015), 50-62. doi: 10.1016/j.aquatox.2014.10.013

  doiwww.sciencedirect.com

• Ferreira, Marta ; Santosa, Pedro ; Rey-Salgueiroa, Ledicia ; Žaja, Roko ; Reis-Henriques, Maria Armanda ; Smital, Tvrtko | The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European Seabass (Dicentrarchus labrax) primary hepatocytes // Chemosphere, 100 (2014), 152-159. doi: 10.1016/j.chemosphere.2013.11.051

  doiwww.sciencedirect.com

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish uptake transporter Oatp1d1 (Slco1d1) // Toxicology and applied pharmacology, 280 (2014), 149-158. doi: 10.1016/j.taap.2014.07.015

  doidx.doi.org

• Bošnjak, Ivana ; Zaja, Roko ; Sauerborn Klobučar, Roberta ; Šver, Lidija ; Franekić, Jasna ; Smital, Tvrtko | Identification of ABC Transporter Genes in Gonad Tissue of two Mediterranean Sea Urchin Species: Black, Arbacia lixula L., and Rocky, Paracentrotus lividus L. // Bulletin of environmental contamination and toxicology, 91 (2013), 4; 415-419. doi: 10.1007/s00128-013-1021-8

  doilink.springer.com

• Traven, Luka ; Mićović, Vladimir ; Vukić Lušić, Darija ; Smital, Tvrtko | The responses of the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity in sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a polluted site: implications for their use in environm // Environmental monitoring and assessment, 185 (2013), 11; 9009-9018. doi: 10.1007/s10661-013-3230-3

  doilink.springer.com

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel Organic anion transporting polypeptide // The Journal of biological chemistry, 288 (2013), 47; 33894-33911. doi: 10.1074/jbc.M113.518506

  doiwww.jbc.orgwww.jbc.org

• Zaja, Roko ; Terzić, Senka ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Ahel, Marijan ; Smital, Tvrtko | Identification of P-Glycoprotein Inhibitors in Contaminated Freshwater Sediments // Environmental science & technology, 47 (2013), 9; 4813-4821. doi: 10.1021/es400334t

  doipubs.acs.org

• Smital, Tvrtko ; Terzić, Senka ; Lončar, Jovica ; Senta, Ivan ; Žaja, Roko ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut-Erik ; Thomas, Kevin V. ; Ahel, Marijan | Prioritisation of organic contaminants in a river basin using chemical analyses and bioassays // Environmental science and pollution research, 20 (2013), 3; 1384-1395. doi: 10.1007/s11356-012-1059-x

  doird.springer.comlink.springer.com

• Della Torre, Camilla ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Focardi, Silvano ; Corsi, Ilaria | Interaction of ABC transport proteins with toxic metals at the level of gene and transport activity in the PLHC-1 fish cell line // Chemico-biological interactions, 198 (2012), 1/3; 9-17. doi: 10.1016/j.cbi.2012.04.008

  doiwww.sciencedirect.com

• Reifferscheid, Georg ; Maes, Hanna ; Allner, Bernhard ; Badurova, Jana ; Belkin, Shimshon ; Blum, Kerstin ; Brauer, Frank ; Bressling, Jana ; Domeneghetti, Stefania ; Elad, Tal et al. | International round-robin study on the Ames fluctuation test // Environmental and molecular mutagenesis, 53 (2012), 3; 185-197. doi: 10.1002/em.21677

  doionlinelibrary.wiley.com

• Ahel, Marijan ; Mikac, Nevenka ; Smital, Tvrtko | Water resources and wastewater management in the Sava River Basin // Danube News, 13 (2011), 24; 13-15

  www.iad.gs

• Fischer, Stephan ; Lončar, Jovica ; Žaja, Roko ; Schnell, Sabine ; Schirmer, Kristin ; Smital, Tvrtko ; Luckenbach, Till | Constitutive mRNAexpression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss) // Aquatic toxicology, 101 (2011), 2; 438-446. doi: 10.1016/j.aquatox.2010.11.010

  doiwww.sciencedirect.comdoi.org

• Žaja, Roko ; Lončar, Jovica ; Popović, Marta ; Smital, Tvrtko | First characterisation of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line // Aquatic toxicology, 103 (2011), 1/2; 53-62. doi: 10.1016/j.aquatox.2011.02.005

  doiwww.sciencedirect.comdoi.org

• Smital, Tvrtko ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Pivčević, Branka ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin. V. ; Ahel, Marijan | Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays // Ecotoxicology and environmental safety, 74 (2011), 4; 844-851. doi: 10.1016/j.ecoenv.2010.11.010

  doiwww.sciencedirect.comdoi.org

• Bošnjak, Ivana ; Šegvić, Tanja ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Mladineo, Ivona | Sea Urchin Embryotoxicity Test for Determination of Environmental Contaminants–Potential Role of the MRP Proteins // Water, air and soil pollution, 217 (2011), 1-4; 627-636. doi: 10.1007/s11270-010-0615-6

  doilink.springer.comdoi.org

• Sauerborn Klobučar, Roberta ; Žaja, Roko ; Franjević, Damjan ; Brozović, Anamaria ; Smital, Tvrtko | Presence of Ecotoxicologically Relevant Pgp- and MRP- Transcripts and Proteins in Cyprinid Fish // Arhiv za higijenu rada i toksikologiju, 61 (2010), 2; 175-181

  hrcak.srce.hrhrcak.srce.hr

• Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): phylogenetic analysis and tissue distribution // Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 155 (2010), 3; 327-335. doi: 10.1016/j.cbpa.2009.11.011

  doidoi.orgwww.sciencedirect.com

• Lončar, Jovica ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss) // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 151 (2010), 2; 209-215. doi: 10.1016/j.cbpc.2009.10.009

  doiwww.sciencedirect.comdoi.org

• Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko | A novel ABC transporter: the first insight into zebrafish (Danio rerio) Abch1 // Marine environmental research, 69 (2010), S1; S11-S13. doi: 10.1016/j.marenvres.2009.10.016

  doiwww.sciencedirect.comwww.sciencedirect.com

• Bošnjak, Ivana ; Uhlinger, Kevin R. ; Heim, Wesley ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Coale, Kenneth ; Epel, David ; Hamdoun, Amro | Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not Organic, Mercury in Sea Urchin Embryos // Environmental science & technology, 43 (2009), 21; 8374-8380. doi: 10.1021/es901677r

  doipubs.acs.org

• Žaja, Roko ; Munić, Vesna ; Sauerborn Klobučar, Roberta ; Ambriović-Ristov, Andreja ; Smital, Tvrtko | Cloning and molecular characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes // Aquatic toxicology, 90 (2008), 4; 322-332

• Žaja, Roko ; Munić, Vesna ; Smital, Tvrtko | Cloning and mRNA expression analysis of an ABCG2 (BCRP) efflux transporter in rainbow trout (Oncorhynchus mykiss) liver and primary hepatocytes // Marine environmental research, 66 (2008), 1; 77-79. doi: 10.1016/j.marenvres.2008.02.028

  doiwww.sciencedirect.comdoi.org

• Žaja, Roko ; Caminada, Daniel ; Lončar, Jovica ; Fent, Karl ; Smital, Tvrtko | Development and characterization of P-glycoprotein 1 (Pgp1 ; ABCB1) mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line // Toxicology and applied pharmacology, 227 (2008), 2; 207-218. doi: 10.1016/j.taap.2007.11.001

  doiwww.sciencedirect.comwww.sciencedirect.com

• Epel, David ; Stevenson, Charlotte N. ; MacManus-Spencer, Laura A. ; Luckenbach, Till ; Hamdoun, Amro ; Smital, Tvrtko | Efflux transporters: newly appreciated roles in protection against pollutants // Environmental science & technology, 42 (2008), 11; 3914-3920. doi: 10.1021/es087187v

  doipubs.acs.orgdoi.org

• Traven, Luka ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Mićović, Vladimir | CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – In vitro evaluation using the PLHC-1 fish hepatoma cell line // Toxicology in vitro, 22 (2008), 6; 1648-1656. doi: 10.1016/j.tiv.2008.06.012

  doiwww.sciencedirect.comwww.sciencedirect.com

• Källqvist, Torsten ; Milačič, Radmila ; Smital, Tvrtko ; Thomas, Kevin V ; Vranes, Sanja ; Tollefsen, Knut-Erik | Chronic toxicity of the Sava River (SE Europe) sediments and river water to the algae Pseudokirchneriella subcapitata // Water research, 42 (2007), 8-9; 2146-2156. doi: 10.1016/j.watres.2007.11.026

  doiwww.sciencedirect.com

• Žaja, Roko ; Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line // Aquatic toxicology, 81 (2007), 365-376

• Žaja, Roko ; Klobučar, Goran I.V. ; Sauerborn Klobučar, Roberta ; Hackenberger, Branimir K. ; Smital, Tvrtko | Haemolymph as compartment for efficient and non-destructive determination of Pgp mediated MXR activity in bivalves // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 143 (2006), 1; 103-112-x

• Smital, Tvrtko ; Luckenbach, Till ; Sauerborn, Roberta ; Hamdoun, M. Amro ; Vega, L. Rebecca ; Epel, David | Emerging contaminants - pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms // Mutation research, 552 (2004), 101-117-x

• Pivčević, Branka ; Sauerborn Klobučar, Roberta ; Krča, Sanja ; Žaja, Roko ; Jelaska, Dalibor ; Smital, Tvrtko ; Britvić Smiljana | Methods of molecular biology in ecotoxicological research // Periodicum biologorum, 106 (2004), 2; 121-125-x

• Sauerborn, Roberta ; Stupin Polancec, Darija ; Zaja, Roko ; Smital, Tvrtko | Identification of the multidrug resistance-associated protein (mrp) related gene in red mullet (Mullus barbatus) // Marine environmental research, 58 (2004), 2-5; 199-204. doi: 10.1016/j.marenvres.2004.03.120

  doidx.doi.orgwww.sciencedirect.com

• Smital, Tvrtko ; Sauerborn, Roberta ; Hackenberger, Branimir | Inducibility of the multixenobiotic resistance mechanism (MXR) transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha // Aquatic toxicology, 65 (2003), 443-465-x

• Smital, Tvrtko ; Sauerborn, Roberta | Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio // Marine environmental research, 54 (2002), 3/5; 449-453. doi: 10.1016/S0141-1136(02)00155-1

  doiwww.sciencedirect.comwww.sciencedirect.com

• Ramljak, Sanja ; Hackenberger, Branimir ; Smital, Tvrtko ; Britvić, Smiljana | Evaluation of the genotoxic and cytochrome P450 monooxigenase-inhibitory potential of Dicuran on procaryotic and eucaryotic test systems // Journal of environmental science and health. Part B, 35 (2000), 6; 751-770

• Smital, Tvrtko ; Sauerborn, Roberta ; Pivčević, Branka ; Krča, Sanja ; Kurelec, Branko | Interspecies differences in P-glycoprotein mediated activity of multixenobiotic resistance mechanism in several marine and freshwater invertebrates // Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 126 (2000), 2; 175-186. doi: 10.1016/s0742-8413(00)00110-9

  doiwww.sciencedirect.com

• Osmak, Maja ; Brozović, Anamaria ; Ambriović-Ristov, Andreja ; Hadžija, Mirko ; Pivčević, Branka ; Smital, Tvrtko | Inhibition of apoptosis is the cause of resistance to doxorubicin in human breast adenocarcinoma cells // Neoplasma, 45 (1998), 4; 223-230

  www.ncbi.nlm.nih.gov

• Kurelec, Branko ; Britvić, Smiljana ; Pivčević, Branka ; Smital, Tvrtko | Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment // Marine environmental research, 46 (1998), 1-5; 415-419-x. doi: 10.1016/S0141-1136(97)00065-2

  doiwww.sciencedirect.com

• Smital, Tvrtko ; Kurelec, Branko | The activity of multixenobiotic resistance mechanism determined by rhodamine B-efflux method as a biomarker of exposure // Marine environmental research, 46 (1998), 1-5; 443-447-x. doi: 10.1016/S0141-1136(97)00087-1

  doiwww.sciencedirect.com

• Smital, Tvrtko ; Kurelec, Branko | The concentrations of inhibitors of multixenobiotic resistance mechanism in natural waters: The direct in vivo demonstration of their effect // Environmental toxicology and chemistry, 16 (1997), 10; 2164-2170-x

• Smital, Tvrtko ; Pivčević, Branka ; Kurelec, Branko | Reversal of multidrug resistance by extract from a marine algae Caulerpa taxifolia // Periodicum biologorum, 98 (1996), 2; 197-203

Review article (scientific)

• Kurelec, Branko ; Smital, Tvrtko ; Britvić, Smiljana ; Pivčević, Branka ; Krča, Sanja ; Jelaska, Dalibor ; Balen, Sofija ; Sauerborn, Roberta ; Mustajbegović, Suada | Multixenobiotic resistance mechanism in aquatic organisms // Periodicum biologorum, 99 (1997), 3; 319-328

Other

• Smital, Tvrtko ; Kurelec, Branko | The chemosenzitizers of multixenobiotic resistance mechanism in aquatic invertebrates : a new class of pollutants // Mutation research. Fundamental and molecular mechanisms of mutagenesis, 399 (1998), 1; 43-53. doi: 10.1016/s0027-5107(97)00265-0

  doiwww.sciencedirect.com

Preliminary communication

• Kurelec, Branko ; Smital, Tvrtko ; Pivčević, Branka ; Eufemia, Nancy ; Epel, David | Multixenobiotic resistance, P-glycoprotein, and chemosensitizers // Ecotoxicology, 9 (2000), 5; 307-327-x

  www.springerlink.com

Professional paper

• Smital, Tvrtko ; Lončar, Jovica ; Bakran-Petricioli, Tatjana ; Petricioli, Donat | Pregled recentnih istraživanja usmjerenih određivanju ekotoksikološkog učinka proizvodnih plinskih platformi u sjevernom Jadranu // Naftaplin = Nafta i plin, 36 (2016), 145-146; 89-102

• Bakran-Petricioli, Tatjana ; Smital, Tvrtko ; Petricioli, Donat ; Mlinarić, Damir | Obraštaj na plinskim platformama u Jadranu kao pokazatelj stanja okoliša // Naftaplin = Nafta i plin, 35 (2015), 142; 72-80

  bib.irb.hr

Review, commentary, critique

• Smital, Tvrtko | Physiological adaptations of animals in the aquatic environment By Čedomil Lucu // Periodicum biologorum, 116 (2014), 3; 331-333

  hrcak.srce.hr

Review article (professional)

• Ahel, Marijan ; Antičić, Tome ; Balog, Tihomir ; Bilić, Nevenko ; Guberina, Branko ; Katušić Hećimović, Silva ; Jerić, Ivanka ; Klanjšček, Tin ; Legović, Tarzan ; Musić, Svetozar et al. | The Ruder Boskovic Institute – Today and Tomorrow // Periodicum biologorum, 112 (2010), 4; 369-374

  hrcak.srce.hr

Conference abstract

• Bakija Alempijević, Saranda; Mihaljević, Ivan; Dragojević, Jelena; Smital, Tvrtko; Frka, Sanja; Strmečki Kos, Slađana | The impact of nitrated monoaromatic hydrocarbons from atmospheric aerosols on different levels of biological organisation in aquatic systems // 8th Faculty of Science PhD Student Symposium: Book of Abstracts / Posarić, Laura; Gmižić, Daria; Ostojić, Tea et al. (ur.). | Zagreb: Faculty of Science, University of Zagreb, Zagreb, Croatia, 2024. str. 48-48

  drive.google.comdigitalna.nsk.hr

• Ivanković, Klaudija ; Dragojević, Jelena ; Mihaljević, Ivan ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Kinetics of uptake and elimination of complex drug mixture in zebrafish (Danio rerio) // Abstract book of SETAC Europe 33rd Annual Meeting “Data-driven environmental decision-making”. | Dublin: Society of Environmental Toxicology and Chemistry (SETAC), 2023. str. 274-274

• Karaica, Dean ; Mihaljević, Ivan ; Vujica, Lana ; Dragojević, Jelena ; Lončarić, Nora ; Bošnjak, Arvena ; Otten, Cecile ; Lončar, Jovica ; Smital, Tvrtko | Optimized protocol for whole-mount immunohistochemistry in zebrafish embryos (Danio rerio) // Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2022. str. 90-90

  congress2022.hdbmb.hrcongress2022.hdbmb.hr

• Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Frka, Sanja ; Smital, Tvrtko ; Strmečki Kos, Slađana | Kvantifikacija i ekotoksikologija nitro-monoaromatskih ugljikovodika u atmosferskim lebdećim česticama PM10 izgaranja biomase // Znanstvena škola o okolišu 2022: Multidisciplinarni pristup istraživanju mikro- i nano- čestica u prirodnim sustavima : knjiga sažetaka. | Zagreb, 2022. str. 6-6

  znanskola2022.com.hr

• Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Dragojević, Jelena ; Frka, Sanja ; Smital, Tvrtko ; Strmečki Kos, Slađana | Exploring ecotoxicological effects of nitromonoaromatic compounds by in vitro and in vivo bioassays / Ispitivanje ekotoksičnih učinaka nitromonoaromatskih spojeva in vitro i in vivo biotestovima // 6. Simpozij studenata doktorskih studija PMF-a : Knjiga sažetaka = 6th Faculty of Science PhD Student Syposium : Book of Abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2022. str. 300-301

  www.pmf.unizg.hr

• Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Dragojević, Jelena ; Strmečki Kos, Slađana ; Frka, Sanja ; Smital, Tvrtko | Ekotoksični učinci metil-nitrokatehola // Znanstvena škola o okolišu 2021: Sveobuhvatni pristup istraživanju antropogenih pritisaka na okoliš : knjiga sažetaka. | Zagreb, 2022. str. 9-9

  znanskola2021.com.hr

• Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Dragojević, Jelena ; Strmečki Kos, Slađana ; Frka, Sanja ; Smital, Tvrtko | Ecotoxicological Effects of Methylnitrocatechols // 21st European Meeting on Environmental Chemistry : Book of Abstracts. | Beograd: Serbian Chemical Society, 2021. str. 161-161

  emec21.rs

• Miloloža, Martina ; Bule, Kristina ; Cvetnić, Matija ; Ukić, Šime ; Markić, Marinko ; Bolanča, Tomislav ; Ocelić Bulatović, Vesna ; Dragojević, Jelena ; Smital, Tvrtko ; Kučić Grgić, Dajana | Ispitivanje toksičnosti mikroplastike na Chlorellu sp., Pseudomonas putidu i Danio rerio // 18. Ružičkini dani: Danas znanost – sutra indistrija. | Zagreb : Osijek: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Prehrambeno tehnološki fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku, 2020. str. 152-152

  www.hdki.hr

• Katalinić, Maja ; Lončar, Jovica ; Miš, Katarina ; Vrhovac Madunić, Ivana ; Smital, Tvrtko ; Pirkmajer, Sergej | Human muscle cells as a model to study the expression and physiological role of the NRE enzyme // 44th FEBS Congress. | Krakov, 2019, P25001, 1

  2019.febscongress.org2019.febscongress.org

• Dragojević, Jelena ; Mihaljević, Ivan ; Smital, Tvrtko | Interaction of zebrafish (Danio rerio) organic anion transporter 2d (Oat2d) with xeno- and endobiotics // 10th Congress of Toxicology in Developing Countries : book of abstracts. | Beograd: Serbian Society of Toxicology, 2018. str. 135-136

  dais.sanu.ac.rs

• Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Smital, Tvrtko | Characterization of zebrafish (Danio rerio) organic anion transporters Oat1 and Oat3 // 2nd International FishMed Conference on Zebrafish Research : Abstract Book. | Varšava: International Institute of Molecular and Cell Biology in Warsaw, 2018. str. 60-60

• Terzić, Senka ; Kostanjevečki, Petra ; Krizman Matasić, Ivona ; Senta, Ivan ; Jurina, Tamara ; Udiković-Kolić, Nikolina ; Ćurko, Josip ; Matošić, Marin ; Lončar, Jovica ; Mihaljević, Ivan et al. | Evaluation of macrolide antibiotic transformation in model biodegradation and ozonation experiments using target and non-target analyses and ecotoxicological bioassays // SETAC Europe 28th Annual Meeting : Abstract Book. | Bruxelles: ociety of Environmental Toxicology and Chemistry Europe, 2018. str. 19-19

  www.setac.org

• Dragojević, Jelena ; Mihaljević, Ivan ; Marić, Petra ; Popović, Marta ; Smital, Tvrtko | Interaction of zebrafish Organic anion transporters (Oats) with endo- and xenobiotics // Workshop "Cyanotoxins - Toxicity, Health and Environmental Impact" : Programme and abstracts. | Novi Sad: Faculty of Sciences, 2017. str. 31-31

• Dragojević, Jelena ; Mihaljević, Ivan ; Smital, Tvrtko | Functional characterization of zebrafish (Danio rerio) organic anion transporter 2d (Oat2d) // Book of abstracts of 10th European Zebrafish Meeting. | 2017. str. 572-572

• Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Smital, Tvrtko | Determining the type of interaction between zebrafish Oct1 and endo- and xenobiotics // Abstract Book - International FishMed Conference on Zebrafish Research. | Varšava: International Institute of Molecular and Cell Biology in Warsaw, 2016. str. 64-64

• Smital, Tvrtko ; Hamer, Bojan ; Bakran-Petricioli, Tatjana ; Petricioli, Donat ; Mlinarić, Damir | Current practices in environmental impact assessment of drilling and gas exploitation activities in the Croatian part of the Adriatic Sea // Knjiga sažetaka s 8th International Oil & Gas Conference and Exhibition (Šibenik, Hrvatska, 13. - 16. 10. 2015.). | Zagreb: Hrvatska udruga naftnih inženjera i geologa (HUNIG), 2015. str. 191-192

• Lončar, Jovica ; Krznar, Petra ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | First characterization of Multidrug and Toxin Extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 168-168

• Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Smital, Tvrtko | Characterization of organic cation transporters in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 61-61

• Marić, Petra ; Mihaljević, Ivan ; Lončar, Jovica ; Dragojević , Jelena ; Smital, Tvrtko | Interactions of secondary metabolites from cyanobacteria and invasive tropical algae with the cellular detoxification mechanism in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 176-176

• Mihaljević, Ivan ; Glisić, Branka ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Fent, Karl ; Kovačević Radmila ; Smital, Tvrtko | Characterization of glutathione-S-transferases in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 180-180

• Smital, Tvrtko ; Mihaljević, Ivan ; Lončar, Jovica ; Popović, Marta ; Žaja, Roko | Functional characterization of MATE (SLC47A) and OCT (SLC22A) transporters in zebrafish (Danio rerio) // PRIMO 18 - 18th International symposium on Pollutant Responses in Marine Organisms. | Trondheim: University of Trondheim, Norway, 2015. str. 119-119

• Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Ljubojević, Marija ; Carol Herak Kramberger ; Micek, Vedran ; Vrhovac, Ivana ; Ivković Dupor, Jana ; Mihaljević, Ivan ; Marić, Petra et al. | Chloride formate exchanger (CFEX - slc26a6) in rat organs ; sex-dependent expression in kidneys // Book of Abstracts of the FEBS3+Meeting “Molecules of Life”. | Ljubljana: Slovenian Biochemical Society, 2015. str. 28-28

• Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković, Jana ; Mihaljević, Ivan ; Marić, Petra et al. | Cell localization and sex-dependent expression of chloride/formate exchanger CFEX (Slc26a6) in rat kidneys // The Interplay of Biomolecules. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2014. str. 100-100

• Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Mihaljević, Ivan ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković, Jana ; Burckhardt, Birgitta et al. | Immunolocalization of chloride-formate exchanger (Slc26a6) in various rat tissues ; sex-dependent expression in kidneys // Experimental animals in scientific research. | Zagreb, 2014. str. 56-57

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | First insight into non-mammalian SLCs: functional characterization of zebrafish (Danio rerio) uptake transporters (Solute Carrier families SLC21 and SLC22) // The EMBO Meeting 2011. | Beč, 2011. str. 139-139

• Ahel, Marijan ; Terzić, Senka ; Lončar, Jovica ; Mikac, Iva ; Žaja, Roko ; Senta, Ivan ; Popović, Marta ; Sauerborn Klobučar, Roberta ; Tollefsen, Knut-Erik ; Thomas, Kevin V et al. | Effects-directed Analysis of Contaminated Sediments from the Sava River, Croatia // Ecosystem Protection in a Sustainable World: A Challenge for Science and Regulation. | Milano: Society of Environmental Toxicology and Chemistry (SETAC), Europe Office, 2011. str. 31-31

• Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin V ; Smital, Tvrtko | Prioritization of hazardous chemical contaminants in the Sava River basin using EDA approach // Characterization of hazardous chemical contamination-from environmental chemistry and toxicology to risk assessment. | Zagreb: Institute Ruđer Bošković, 2010. str. 20-20

• Loncar, Jovica ; Fischer, Stephan ; Zaja, Roko ; Wellner, Peggy ; Luckenbach, Till ; Schirmer, Kristin ; Smital, Tvrtko | Gene expression and functional analysis of toxicologically important ABC transporters in rainbow trout (Oncorhynchus mykiss) tissues and cell lines // ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Disease: Abstract Book. | Innsbruck: Federation of European Biochemical Societies (FEBS), 2010. str. 162-162

• Lončar, Jovica ; Fischer, Stephan ; Žaja, Roko ; Wellner, Peggy ; Luckenbach, Till ; Schirmer, Kristin ; Smital, Tvrtko | Gene expression and functional analysis of toxicologically important ABC transporters in rainbow trout (Oncorhynchus mykiss) tissues and cell lines // ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases. | Beč, 2010. str. 162-162

• Smital, Tvrtko ; Terzić, Senka ; Žaja, Roko ; Lončar, Jovica ; Mikac, Iva ; Popović, Marta ; Senta, Ivan ; Ahel, Marijan | Effect-directed analyses of hazardous chemical contaminants in freshwater sediments impacted by industrial effluents // Science and Technology for Environmental Protection: Book of Abstracts. | Sevilla: Society of Environmental Toxicology and Chemistry (SETAC), Europe Office, 2010. str. 139-139

• Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Mjerenje genotoksičnog učinka Ames testom u XAD-7 koncentratima morske vode Sjevernog, Srednjeg i Južnog Jadrana // 11. stručni sastanak laboratorija ovlaštenih za ispitivanje voda. | 2010. str. 61-63

• Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Ames versus Ames II assay - genotoxicity assessment of environmental samples // NATO SfP 982590 project workshop: Characterisation of hazardous chemical contamination – from environmental chemistry and toxicology to risk assessment. | Zagreb: IRB, Zagreb, 2010. str. 38-38

• Terzić, Senka ; Lončar, Jovica ; Mikac, Iva ; Popović, Marta ; Senta, Ivan ; Žaja, Roko ; Smital, Tvrtko ; Ahel, Marijan | Assessment of hazardous organic contamination in freshwater sediments impacted by industrial effluents // The First Joint PSE-SETAC Conference on Ecotoxicology - Ecotoxicology in the real world : Book of abstracts. | Krakov, 2009. str. 51-51

• Bošnjak, Ivana ; Uhlinger, Kevin R. ; Heim, Wesley ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Coale, Kenneth ; Epel, David ; Hamdoun, Amro | Multidrug efflux transporters limit accumulation of inorganic, but not organic, mercury in sea urchin embryos // EMBO Young Scientists Forum. | Zagreb, 2009. str. 10-10

  www.bioinfo.hr

• Ahel, Marijan ; Lončar, Jovica ; Mikac, Iva ; Popović, Marta ; Senta, Ivan ; Terzić, Senka ; Žaja, Roko ; Tollefsen, Knut-Erik ; Thomas, Kevin V. ; Smital, Tvrtko | Characterization of organic contaminants in municipal wastewater of the city of Zagreb by chemical methods and bioassays // The First Joint PSE-SETAC Conference on Ecotoxicology - Ecotoxicology in the real world : Book of abstracts. | Krakov: Jagiellonian University & Polish Society of Ecotoxicology & Society of Environmental Toxicology and Chemistry - Central and Eastern Europe Branch, 2009. str. 50-50

• Hamer, Bojan; Jakšić, Željko; Vucelić, Vedran; Krča, Sanja; Smital, Tvrtko; Reifferscheid, Georg; Smodlaka, Nenad; Batel, Renato | Temporal and Spatial variations of Seawater Genotoxicity, Mutagenicity and mussel DNA integrity along the Adriatic coast, Croatia: A long term study - "Project Adriatic" (1998-2007) // 14th International Symposium on Toxicity Assessment - Program and abstract book. | Metz, 2009. str. 103-103

• Lončar, Jovica ; Popovic, Marta ; Caminada, Daniel ; Fent, Karl ; Smital, Tvrtko | Development and characterization of the P- glycoprotein 1 (Pgp1 ; ABCB1) mediated doxorubicin-reistant PLHC-1 hepatoma fish cell line // TP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases: Book of Abstracts. | Innsbruck: Federation of European Biochemical Societies (FEBS), 2008. str. 131-131

• Bošnjak, Ivana ; Coale, Kenneth ; Franekić Čolić, Jasna ; Smital, Tvrtko ; Epel, David ; Hamdoun, Amro | Transportna aktivnost multidrug resistance associated proteina (MRP) posreduje razlike u akumulaciji i toksičnosti anorganske i organske žive u embrijima morskih ježinaca // 50 godina molekularne biologije u Hrvatskoj - zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 81-81

• Pivčević, Branka ; Skukan, Ivana ; Lončar, Jovica ; Smital, Tvrtko | Ecotoxicological analysis of daily and weekly profile of influent and effluent waste waters of the city of Čakovec, Croatia // Emerging contaminants in wastewaters: monitoring tools and treatment technologies : 2nd EMCO workshop : Abstracts. | 2007. str. 111-111

• Bošnjak, Ivana ; Epel, David ; Johnson, Ken ; Franekić Čolić, Jasna ; Smital, Tvrtko ; Hamdoun, Amro M. | Multidrug resistance-associated protein (MRP) protects sea urchin embryos (Strongylocentrotus purpuratus) against mercuric chloride // Pollutant responses in marine organisms ; 14th International symposium. | Florianopolis: Universidade Federal de Santa Catalina, 2007. str. 126-126

• Bošnjak, Ivana ; Coale, Kenneth ; Franekić Čolić, Jasna ; Smital, Tvrtko ; Epel, David ; Hamdoun, Amro | Multidrug resistance associated protein (MRP) transport activity mediates differences in susceptibility to inorganic and organic mercury in sea urchin (Strongylocentrotus purpuratus) embryos // ABC Transport Proteins in Environmental Health and Toxicology. | Siena, 2007. str. 22-22

• Pivčević, Branka ; Skukan, Ivana ; Smital, Tvrtko | Elimination of MXR inhibitory pharmaceuticals from waste waters by membrane bioreactor, reversal osmosis, nanofiltration and ozonization // ABC transport proteins in environmental health and toxicology. | Siena: University of Siena, 2007

• Lončar, Jovica ; Žaja, Roko ; Ahel, Marijan ; Smital, Tvrtko | Ekotoksikološka karakterizacija otpadnih voda Erod biotestom (PLHC-1 stanična linija) i testom toksičnosti na algama (Pseudokirchneriella subcapitata). // Zbornik sažetaka. | Rovinj: HDB 1885, 2006. str. 358-359

• Pivčević, Branka ; Maltar Tanja ; Smital, Tvrtko | Određivanje estrogenosti uzoraka priobalne vode Jadranskog mora i vode iz pročišćivača miješanih otpadnih voda upotrebom YES (“yeast estrogen screen”) biotesta // 9th Croatian Biological Congress with International Participation. | 2006. str. 350-351

• Dražić, Marica Maja ; Bubalo, Dragan ; Smital, Tvrtko ; Krča, Sanja ; Britvić, Smilja ; Kezić, Nikola | Ekspresija mehanizma multiksenobiotičke otpornosti izlaganjem pčela aktivnim tvarima lijekova // Zbornik radova. | Osijek: Poljoprivredni fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku, 2005. str. 291-292-x

• Sauerborn Klobučar, Roberta ; Krča, Sanja ; Brozović, Anamaria ; Stupin Polančec, Darija ; Žaja, Roko ; Smital, Tvrtko | Determination of the presence of P-gp- and MRP-related transcripts and proteins in cyprinid fish species // Abstracts of the 13rd International Symposyum on Pollutant Responses In Marine Organisms (PRIMO). | 2005

• Raspor, Biserka ; Erk, Marijana ; Filipović, Vlatka ; Pavičić, Jasenka ; Jurič, Dušica ; Dragun, Zrinka ; Britvić, Smilja ; Krča, Sanja ; Pivčević, Branka ; Smital, Tvrtko et al. | An integrated environmental monitoring system for Croatian freshwater, estuarine and coastal marine areas : the CROWAT project // Abstracts of the SETAC Europe 14th Annual Meeting on Environmental Science Solutions : A Pan-European Perspective. | Prag: Society of Environmental Toxicology and Chemistry (SETAC), 2004. str. 244-244

• Raspor, Biserka ; Erk, Marijana ; Filipović, Vlatka ; Pavičić, Jasenka ; Jurič, Dušica ; Dragun, Zrinka ; Britvić, Smilja ; Krča, Sanja ; Pivčević, Branka ; Smital, Tvrtko et al. | CROWAT projekt : sustav monitoringa okoliša za kopnene vode, estuarije i more u Hrvatskoj // 8. hrvatski biološki kongres s međunarodnim sudjelovanjem : Zbornik sažetaka = 8th Croatian Biological Congress with International Participation : Proceeding of abstracts. | Zagreb: Hrvatsko biološko društvo, 2003. str. 347-348

• Dražić, Marica Maja ; Smital, Tvrtko ; Britvić, Smilja ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Kezić, Nikola | EXPRESSION OF MULTIXENOBIOTIC RESISTANCE IN EUROPEAN HONEYBEE STRAINS (Apis mellifera L.) // Final Programe and Book of Abstract, XXXVIIIth APIMONDIA, International Apicultural Congress, Ljubljana, Slovenia, August 24 - 29. 2003.. | Ljubljana: APIMONDIA, 2003. str. 674-675-x

• Hackenberger K., Branimir ; Britvić-Budicin, Smiljana ; Smital, Tvrtko ; Stepić, Sandra | The possible influence of some physiological parameters on EROD-activity data valuation // Risk Assessment and Management of Large Contamination Sites : Congress Proceedings. | Halle, 2002

• Hackenberger K., Branimir ; Smital, Tvrtko ; Britvić-Budicin, Smiljana ; Stepić, Sandra ; Pavlić, Želimira ; Klobučar I.V., Goran | Eksperimentalni organizmi u suvremenom praćenju zagađenja vodenog okoliša / Experimental organisms in modern monitoring water pollution // Prva hrvatska konferencija Hrvatskog društvo kemijskih inženjera i tehnologa - Ekoinženjerstvo 2002 : knjiga sažetaka. | Zagreb, 2002. str. 108-108

• Dražić, Marica Maja ; Smital, Tvrtko ; Britvić Budicin, Smiljana ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Kezić, Nikola | Multixenobiotic resistance mechanism in honeybees // Report of the 47th seminar in Blaubeuren near Ulm Heinrich-Fabri-Insitut of the Ebergard-Karls-University Tubingen 3-5 April 2000. | Pariz: INRA/DIB-AGIB/EDPm Sciences, 2000. str. 601-601-x

• Dražić, Marica Maja ; Smital, Tvrtko ; Britvić-Budučin, Smiljana ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Berg, Stefan ; Buchler, Ralph ; Kezić, Nikola | Activity of multixenobiotic resistance mechanism in honeybees // Schedule and Summaries. Molecular Mechanisms of Disease Tolerance in Honeybees.. | Prag, 2000. str. 8-8-x

Original scientific paper

• Dražić, Maja ; Bubalo, Dragan ; Smital, Tvrtko ; Krča, Sanja, Britvić, Smilja ; Kezić, Nikola | Ekspresija mehanizma multiksenobiotičke otpornosti izlaganjem pčela aktivnim tvarima lijekova // Proceedings, XL Croatian Symposium on Agriculture. | Opatija: Poljoprivredni fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku, 2005. str. 291-293

• Sauerborn, Roberta ; Stupin Polancec, Darija ; Zaja, Roko ; Smital, Tvrtko | Identification of the multidrug resistance-associated protein (MRP) related genes in several marine and freshwater fish species // 12th International Symposium on Pollutant Responses in Marine Organisms (PRIMO12) : conference proceedings. | 2003

Conference abstract

• Karaica, Dean ; Mihaljević, Ivan ; Vujica, Lana ; Dragojević, Jelena ; Bošnjak, Arvena ; Babić, Nency ; Otten Cecile ; Smital, Tvrtko | Improved histological approach for localization and expression analysis of (non)membrane proteins in zebrafish cryosections // FEBS Open Bio, 12, S1, 2022. str. 240-240

• Karaica, Dean ; Breljak, Davorka ; Brzica, Hrvoje ; Lončar, Jovica ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković Dupor, Jana ; Mihaljević, Ivan et al. | CFEX (Slc26a6) in rat kidneys, liver, and small intestine in an experimental model of oxalate nephrolitiasis // Arhiv za higijenu rada i toksikologiju, 2015. str. 228-228

  hrcak.srce.hrhrcak.srce.hr

• Smital, Tvrtko ; Epel, David ; Britivić, Smiljana ; KrČa, Sanja ; Pivčević, Branka ; Sauerborn Klobučar, Roberta ; Žaja, Roko | Inhibitors of the ABC transport proteins as emerging pollutants— Determination and ecotoxicological relevance // Toxicology letters, 2006. str. S43-S44

  www.sciencedirect.com

• Sauerborn Klobučar, Roberta ; Žaja, Roko ; Smital, Tvrtko | ABC transport proteins as mediators of the multixenobiotic resistance (MXR) defence mechanism in aquatic organisms // The FEBS journal, 2005

  onlinelibrary.wiley.com

Unpublished conference paper

• Vujica, Lana; Mihaljević, Ivan; Dragojević, Jelena; Lončar, Jovica; Smital, Tvrtko | Phenotype changes in zebrafish Oatp1d1 mutants // Pollutant Responses in Marine Organisms | Nantes, Francuska, 26.05.2024-29.05.2024

  primo22.org

• Vujica, Lana; Lončar, Jovica; Lučić, Bono; Radman, Katarina; Mihaljević, Ivan; Bertoša, Branimir; Mesarić, Josip; Horvat, Marina; Smital, Tvrtko | First in vitro and in silico characterization of zebrafish (Danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a2.1) // 12th European Zebrafish Meeting | Krakov, Poljska, 09.07.2023-13.07.2023

• Ivanković Koprivić, Klaudija; Dragojević, Jelena; Mihaljević, Ivan; Smital, Tvrtko; Ahel, Marijan; Terzić, Senka | Kinetika akumulacije i eliminacije smjese farmaceutski aktivnih spojeva u modelnom organizmu Danio rerio // Znanstvena škola o okolišu 2023 : Nekonvencionalni pristupi konvencionalnim izazovima | Zagreb, Hrvatska, 27.11.2023-29.11.2023

• Vujica, Lana; Mišić, Lana; Horvat, Marina; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish (danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a3) // HDBMB 2022 Congress – From Science to Knowledge | Brela, Hrvatska, 28.09.2022-01.10.2022

• Vujica, Lana; Mišić, Lana; Horvat, Marina; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish (Danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a3) // 21st International Symposium on Pollutant Responses In Marine Organisms (PRIMO21) | Göteborg, Švedska, 22.05.2022-25.05.2022

• Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Mikac, Iva ; Smital, Tvrtko | Comprehensive Scheme for Non-target Screening of Wastewater and Its Application for the Effect- directed Analysis Municipal Sewage // 13th EuCheMS International Conference on Chemistry and the Environment | Zürich, Švicarska, 11.09.2011-15.09.2011

• Della Torre, Camilla ; Lončar, Jovica ; Žaja, Roko ; Focardi Silvano ; Smital, Tvrtko ; Corsi, Ilaria | INVOLVEMENT OF ABC TRANSPORT PROTEINS IN RESPONSE TO TOXIC HEAVY METALS IN THE PLHC-1 FISH CELL LINE // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | FIRST CHARACTERIZATION OF ZEBRAFISH (Danio rerio) UPTAKE TRANSPORTERS (Solute Carrier families SLC21 and SLC22) // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Glišic, Branka ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Kovačević, Radmila | Phylogenetic and tissue distribution analysis of glutathione-S-transferase family in zebrafish (Danio rerio) // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Smital, Tvrtko ; Žaja, Roko ; Popović, Marta ; Lončar, Jovica | Uptake and efflux transporters versus the adme-tox concept in aquatic toxicology // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Lončar, Jovica ; Žaja, Roko ; Popović, Marta ; Medvedović, Jasna ; Smital, Tvrtko | Tissue distribution and gene expression regulation of MRP9 (abcc12) in rainbow trout and zebrafish // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Terzić, Senka ; Ahel, Marijan ; Smital, Tvrtko | IDENTIFICATION OF POTENT P-GLYCOPROTEIN (ABCB1) INHIBITORS IN CONTAMINATED SEDIMENT SAMPLES // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Žaja, Roko ; Popović, Marta ; Lončar, Jovica ; Fent, Karl, Smital, Tvrtko | Expression and characterization of rainbow trout (Oncorhynchus Mykiss) BCRP (ABCG2) in SF9 insect cells // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica, Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin V ; Smital, Tvrtko | Relative contribution of polar contaminants to the toxicological profiles of the wastewater effluents of the city of Zagreb (Croatia) // SETAC Europe 20th Annual Meeting | Sevilla, Španjolska, 23.05.2010-27.05.2010

Master of Science thesis

• Stepić, Sandra | Utjecaj oksidativnog stresa na izraženost molekularnih biljega kod babuške (Carassius auratus gibelio) i šarana (Cyprinus carpio) / Hackenberger, Dubravka (mentor); Smital, Tvrtko (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2006

• Smital, Tvrtko | In vivo određivanje koncentracije inhibitora mehanizma multiksenobiotičke otpornosti (MXR) u riječnim vodama / Kurelec, Branko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1998

Doctoral thesis

• Frleta Matas, Roberta | BIOAKTIVNI POTENCIJAL I KEMIJSKI SASTAV HIDROALKOHOLNIH EKSTRAKATA DIJATOMEJA SJEVERNOG JADRANA / Šimat, Vida; Smital, Tvrtko (mentor). | Split, Prirodoslovno-matematički fakultet u Splitu, 2025

• Dragojević, Jelena | Characterization of organic anion transporters in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, 2018

• Lončar, Jovica | Function and regulation of ABC transport proteins in rainbow trout (Onchorynchus mykiss) tissues and cell lines / Smital, Tvrtko (mentor). | Zagreb, Sveučilište u Zagrebu, 2015

• Mihaljević, Ivan | Characterization of organic cation transporters in zebrafish (Danio rerio Hamilton, 1882) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku / Sveučilište u Dubrovniku, 2015

• Marić, Petra | Ecotoxicological characterization of cyanobacteria and invasive algae from the genus Caulerpa using the concept of effects-directed analyses (EDA) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku / Sveučilište u Dubrovniku, 2015

• Popović, Marta | Identification, characterization and ecotoxicological relevance of membrane transport protein families SLC21 and SLC22 in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2014

  mobi.unios.hr

• Popović, Marta | Identification, characterization and ecotoxicological relevance of membrane transport protein families SLC21 and SLC22 in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2014

  mobi.unios.hr

• Bošnjak, Ivana | Zaštitna uloga ABC transportnih proteina tijekom ranog embrionalnog razvoja morskih ježinaca / Smital, Tvrtko ; Šver, Lidija (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010

• Žaja, Roko | Karakterizacija apikalnih transportera ABC u hepatocitima kalifornijske pastrve (Oncorhynchus mykiss) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010

• Sauerborn Klobučar, Roberta | Karakterizacija mehanizma multiksenobiotičke otpornosti (MXR) vodenih životinja određivanjem MRP-protein kodirajućih gena / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

• Traven, Luka | Ekotoksikološka karakterizacija sedimenata Riječkog zaljeva upotrebom in vitro biotestova / Mićović, Vladimir ; Smital, Tvrtko (mentor). | Rijeka, Medicinski fakultet u Rijeci, 2009

• Smital, Tvrtko | Aktivnost mehanizma multiksenobiotičke otpornosti u vodenih organizama kao pokazatelj kvalitete okoliša / Kurelec, Branko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1999

Master's thesis (university)

• Bule, Kristina | Određivanje toksičnosti mikroplastike / Kučić Grgić, Dajana ; Smital, Tvrtko (mentor); Miloloža, Martina (neposredni voditelj) . | Zagreb, Fakultet kemijskog inženjerstva i tehnologije, 2020

• Kerkez, Josip | Toksičnost ekstrakata invazivnih tropskih algi roda Caulerpa / Smital, Tvrtko ; Radić Brkanac, Sandra (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2019

  urn.nsk.hr

• Krznar, Petra | Genska ekspresija i filogenija MATE (Multidrug and toxin extrusion) proteina u zebrici, Danio rerio (Hamilton, 1822) / Smital, Tvrtko ; Klobučar, Goran (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013

  urn.nsk.hr

• Krznar, Petra | Genska ekspresija i filogenija MATE (Multidrug and toxin extrusion) proteina u zebrici, Danio rerio (Hamilton, 1822) / Smital, Tvrtko; Klobučar, Goran (mentor); Popović, Marta (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013

  repozitorij.pmf.unizg.hr

• Bartolić, Damir | UTVRĐIVANJE ESTROGENOSTI UZORAKA SEDIMENTA I POVRŠINSKE VODE RIJEKE SAVE BIOTESTOM YES / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2011

• Crnjak, Martina | Utvrđivanje genotoksičnog potencijala uzoraka sedimenta i površinske vode rijeke Save Ames biotestom / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

  zir.nsk.hr

• Šestak, Ivana | Određivanje toksičnosti uzoraka sedimenta potoka Gorjak in vitro biotestovima / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

  zir.nsk.hrurn.nsk.hr

• Marić, Petra | Estrogeni potencijal i koncentracija inhibitora mehanizma multiksenobiotičke otpornosti u sedimentu potoka Gorjak / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

• Šestak, Ivana | Određivanje toksičnosti uzoraka sedimenta potoka Gorjak biotestovima in vitro / Smital, Tvrtko ; Klobučar, Goran (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

  urn.nsk.hr

• Medvedović, Jasna | Molekularna identifikacija i funkcionalna karakterizacija P-glikoproteina (ABCB1) u slatkovodnog školjkaša vrste Unio pictorum (Linnaeus 1758) / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2007

Other articles/contributions

• Britvić, Smiljana ; Krča, Sanja ; Kurelec, Branko ; Lucić, Davor ; Pivčević, Branka ; Smital, Tvrtko | Functional and protein expression of multixenobiotic resistance mechanism in a marine mussel as a biomarker of exposure to polluted environments // MAP Technical Report Series No. 103, UNEP, Athens, pp. 29-41, 1998

  wedocs.unep.orgagris.fao.org

Report

• Raspor, Biserka ; Teskeredžić, Emin ; Smital, Tvrtko ; Picer, Mladen ; Ahel, Marijan | SARIB project Annual Report of Partner 3 (RBI) // Sixth Framework Programme FP6-2002-INCO-WBC-1, 2005

• Raspor, Biserka ; Smital, Tvrtko ; Klobučar, Goran ; Hackenberger, Branimir | An integrated environmental monitoring system for Croatian freshwater, estuarine and coastal marine areas // Research Council of Norway, Project No. 150463, 2005

Member of Croatian Biological Society, Croatian Toxicological Society and International Society of Ecotoxicology and Environmental Safety (SECOTOX).