dr. sc. Tvrtko Smital

voditelj laboratorija

predstojnik zavoda znanstveni savjetnik u trajnom izboru

E-mail

Tvrtko.Smital@irb.hr

Telefon

+385 1 456 1088

Interni broj

1538

Znanstveno-nastavno zvanje

Docent

Zavod

Zavod za istraživanje mora i okoliša

Laboratorij

Laboratorij za molekularnu ekotoksikologiju

Adresa

Institut Ruđer Bošković
Zavod za istraživanje mora i okoliša
Laboratorij za molekularnu eokotoksikologiju
Bijenička 54, 10000 Zagreb
Hrvatska

Životopis

Preuzmi

Obrazovanje

- Osnovna i srednja škola (Gimnazija M.A. Reljković) završena u Vinkovcima, maturirao 1987. god.;

- 1994. god. diplomirao biologiju, smjer dipl. inž. biologije-ekologije na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu;

- 1998. god. magisterij iz prirodnih znanosti, polje biologija, grana toksikologija, na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu;

- 1999. god. doktorat iz prirodnih znanosti, polje biologija, grana ekotoksikologija, na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu.

Područja znanosti

Biologija Biokemija i molekularna biologija

Specifični znanstveni interesi

ekotoksikologija i molekularna biologija

Projekti

Aktualni projekti:

- Ecotoxicological characterization of biologically active substances and complex marine environment samples – Project within the Centre for Excellence for Science and Technology – Integration of Mediterranean Region (ZCI-STIM; https://stim.unist.hr/hr/) (2017-2021) – leading institution University of Split, other partners Ruđer Bošković Institute, Zagreb (IRB) and Mediteranean Institute for Life Sciences (MEDILS); principal investigator.

- Understanding the (eco)toxicological role of selected SLC and MATE transport proteins in zebrafish (Danio rerio) using functional genomics tools, (2020-2023) – Croatian Science Foundation research project – principal investigator;

Nastava

- M. Erk, T. Smital – Kolegij Biološki učinci metala i organskih zagađivala na morske organizme; Doktorski studij iz Oceanologije, Prirodoslovno-matematički fakultet, Sveučilište u Zagrebu;

- T. Smital – Kolegij Ekotoksikologija; Doktorski studij “Zaštita prirode i okoliša”, Sveučilište u Osijeku;

- G. Klobučar, M. Pavlica, V. Garaj-Vrhovac, T. Smital – Kolegij Biomarkeri u biomonitoringu zagađenja okoliša; Doktorski studij iz Biologije, Prirodoslovno-matematički fakultet, Sveučilište u Zagrebu

Istaknute publikacije

SCI publikacije

Smital T, Pivčević B. and Kurelec B. (1996) Reversal of multidrug resistance by extract from the marine alga Caulerpa taxifolia. Period. Biol., 98: 165-171.
Smital T. and Kurelec B. (1997) Inhibitors of the multixenobiotic resistance mechanism in natural waters: In vivo demonstration of their effects. Environ. Toxicol. Chem. 16: 2164-2170.
Kurelec B., Smital T., Britvić S., Pivčević B., Krča S., Jelaska D., Balen S., Sauerborn R. and Mustajbegović S. (1997) Multixenobiotic defence mechanism in aquatic organisms. Period. Biol. 99: 319-328.
Smital. T. and Kurelec B. (1998) The chemosensitizers of multixenobiotic resistance mechanism in aquatic invertebrates; A new class of pollutants. Mutat. Res.-Fund. Mol. M. 399: 45-53.
Kurelec B., Britvić S. and Smital T. (1998) Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment. Mar. Environ. Res. 46: 415-419.
Smital T. and Kurelec B. (1998) The activity of multixenobiotic resistance mechanism determined by rhodamine B - efflux method as a biomarker of exposure. Mar. Environ. Res. 46: 443-447.
Osmak M., Brozović A., Ambriović-Ristov A., Hadžija M., Pivčević B., and Smital T. (1998) Inhibition of apoptosis is the cause of resistance to doxorubicin in human breast adenocarcinoma cells. Neoplasma 45: 223-230.
Kurelec, B., Smital, T., Pivčević, B., Eufemia, N. and Epel, D. (2000) Multixenobiotic resistance, P-glycoprotein, and chemosensitizers. Ecotoxicology 9: 307-327.
Smital, T., Sauerborn, R., Pivčević, B., Krča, S. and Kurelec, B. (2000) Interspecies differences in P-glycoprotein mediated activity of multixenobiotic resistance mechanism in several marine and freshwater invertebrates, Comp. Biochem. Physiol C., 126: 175-186.
Ramljak, S., Hackenberger, B.K., Smital, T. and Britvić, S. (2000) Evaluation of the genotoxic and cytochrome P450 monooxygenase-inhibitory potential of dicuran on procariotic and eucaryotic test systems, J. Environ. Sci. Health B. B35: 751-770.
Smital, T. and Sauerborn, R. (2002) Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio. Mar. Environ. Res. 54: 449-453.
Smital, T., Sauerborn, R. and Hackenberger, B.K. (2003) Inducibility of the P-glycoprotein transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha. Aquat. Toxicol. 65: 443-465.
Sauerborn, R., Stupin Polancec, D., Zaja, R. and Smital, T. (2004) Identification of the multidrug resistance-associated protein (MRP) related gene in the red mullet (Mullus barbatus). Mar. Environ. Res., 58: 199-204.
Smital, T., Luckenbach, T., Sauerborn, R., Hamdoun, A.M., Vega, R.L. and Epel, D. (2004) Emerging contaminants – pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms. Mut. Res.-Fund. Mol. M., 552: 101-117.
Žaja, R., Klobučar, G.I.V., Sauerborn Klobučar, R., Hackenberger, B., and Smital, T. (2006) Haemolymph as compartment for efficient and non-destructive determination of Pgp mediated MXR activity in bivalves. Comp. Biochem. Physiol. C., 143: 103-112.
Žaja, R., Sauerborn Klobučar R. and Smital, T. (2007) Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line. Aquat. Toxicol., 81: 365-376.
Krča, S., Žaja, R., Čalić, V., Terzić, S., Grubešić, M.S., Ahel, M. and Smital, T. (2007) Hepatic biomarker responses to organic contaminants in feral chub (Leuciscus cephalus) – laboratory characterization and field study in the Sava River, Croatia. Environ. Toxicol. Chem., 26: 2620-2633.
Žaja, R., Caminada, D., Lončar, J., Fent, K. and Smital, T. (2008) Development and characterization of P-glycoprotein 1 (Pgp1; ABCB1) mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line. Toxicol. Appl. Pharmacol., 227: 207-218.
Žaja, R., Munić, V., and Smital, T. (2008) Cloning and mRNA expression analysis of an ABCG2 (BCRP) efflux transporter in rainbow trout (Oncorhynchus mykiss) liver and primary hepatocytes. Mar. Environ. Res., 66: 77-79.
Källqvist, T., Milačič, R., Smital, T., Thomas, K.V., Vranes, S. and Tollefsen, K-E. (2008) Chronic toxicity of the Sava River (SE Europe) sediments and river water to the algae Pseudokirchneriella subcapitata. Water Res., 42: 2146-2156.
Epel, D., Stevenson, C.N., MacManus-Spencer, L.A., Luckenbach, T., Hamdoun, A., and Smital, T. (2008) Efflux transporters: newly appreciated roles in protection against pollutants. Environ. Sci. Tech., 42: 3914-3920.
Traven, L., Žaja, R., Lončar, J., Smital, T. and Mićović, V. (2008) CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – In vitro evaluation using the PLHC-1 fish hepatoma cell line. Toxicol. In Vitro, 22: 1648-1656.
Caminada, D., Žaja, R., Smital, T. and Fent, K. (2008) Human pharmaceuticals modulate P-gp1 (ABCB1) transport activity in the fish cell line PLHC-1. Aquat. Toxicol., 90: 214–222.
Žaja, R., Munić, V., Sauerborn Klobučar, R., Ambriović-Ristov, A., Smital, T. (2008) Cloning and functional characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol. 90: 322-332.
Bošnjak, I., Heim, W., Smital, T., Epel, D., Coale, K., Franekić-Čolić, J., Hamdoun, A. (2009) Multidrug resistance associated protein transport activity mediates differences in accumulation and toxicity of inorganic and organic mercury in sea urchin embryos. Environ. Sci. Tech. 43: 8374-8380.
Lončar, J., Popović, M., Žaja, R., Smital, T. (2010) Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Physiol. C. 151: 209-215.
Popović, M., Žaja, R., Lončar, J., Smital, T. (2010) A novel ABC transporter: the first insight into zebrafish (Danio rerio) Abch1. Mar. Environ. Res. 69: S11-S13.
Popović, M., Žaja, R., Smital, T. (2010) Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): phylogenetic analysis and tissue distribution. Comp. Biochem. Physiol. A 155: 327-335.
Bošnjak, I., Šegvić, T., Smital, T., Franekić, J., Mladineo, I. (2011) Sea Urchin Embryotoxicity Test for Environmental Contaminants—Potential Role of the MRP Proteins. Water Air Soil Poll. 217: 627-636.
Fischer, S., Loncar, J., Zaja, R., Schnelle, S., Schirmer, K., Smital, T., Luckenbach, T. (2011) Constitutive mRNAexpression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 101: 438-446.
Smital, T., Terzic, S., Zaja, R., Senta, I., Pivcevic, B., Popovic, M., Mikac, I., Tollefsen, K.E., Thomas, K.V., Ahel, M. (2011) Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays. Ecotoxicol. Environ. Saf. 74: 844-851.
Sauerborn Klobučar, R., Zaja, R., Franjević, D., Brozović, A., Smital, T. (2011) Presence of Ecotoxicologically Relevant Pgp- and MRP- Transcripts and Proteins in Cyprinid Fish. Arh. Hig. Rada Toksikol. 61: 175-181.
Zaja, R., Loncar, J., Popovic, M., Smital, T. (2011) First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line. Aquat. Toxicol. 103: 53-62.
Reifferscheid, G., Maes, H., Allner, B., Badurova, J., Belkin, S., Blum, K., Brauer, F., Bressling, J., Domeneghetti, S., Elad, T., Flückiger-Isler, S., Grummt, H.J., Guertler, R., Hecht, A., Heringa, M., Hollert, H., Huber, S., Kramer, M., Magdeburg, A., Ratte, T., Sauerborn-Klobucar, R., Sokolowski, A., Soldan, P., Smital, T., Stalter, D., Venier, P., Ziemann, C., Zipperle, J., Buchinger, S. (2012) International round-robin study on the Ames fluctuation test. Environ. Mol. Mutag. 53: 185-197.
Della Torre, C., Zaja, R., Loncar, J., Smital, T., Focardi, S., Corsi, I. (2012) Interaction of ABC transport proteins with toxic metals at the level of gene and transport activity in the PLHC-1 fish cell line. Chem. Biol. Interac. 198: 9-17.
Smital, T., Terzić, S., Lončar, J., Senta, I., Zaja, R., Popović, M., Mikac, I., Tollefsen, K-E., Thomas, K.V., Ahel, M. (2013) Prioritisation of organic contaminants in a river basin using chemical analyses and bioassays. Environ. Sci. Poll. Res. 20: 1384-1395.
Zaja, R., Terzić, S., Senta, I., Lončar, J., Popović, M., Ahel, M., Smital, T. (2013) Identification of P-glycoprotein (P-gp, Abcb1) inhibitors in contaminated freshwater sediments. Environ. Sci. Tech. 47: 4813-4821.
Traven, L., Mićović, V., Vukić Lušić, D., Smital, T. (2013) The responses of the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity in sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a polluted site: implications for their use in environmental risk assessment. Environ Monit Assess. 185: 9009-9018.
Bošnjak, I., Zaja, R., Klobučar, R.S., Sver, L., Franekić, J., Smital, T. (2013) Identification of ABC Transporter Genes in Gonad Tissue of Two Mediterranean Sea Urchin Species: Black, Arbacia lixula L., and Rocky, Paracentrotus lividus L. Bull. Environ. Contam. Toxicol. 91: 415-419.
Popovic, M., Zaja, R., Fent, K., Smital, T. (2013) Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel Organic anion transporting polypeptide. J. Biol. Chem. 288: 33894–33911.
Ferreira, M., Santos, P., Rey-Salgueiro, L., Zaja, R., Reis-Henriques, M.A., Smital, T. (2014) The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European seabass (Dicentrarchus labrax) primary hepatocytes. Chemosphere 100: 152-159.
Popovic, M., Zaja, R., Fent, K., Smital, T. (2014) Interaction of environmental contaminants with zebrafish uptake transporter Oatp1d1 (Slco1d1). Toxicol. Appl. Pharmacol. 280: 149-158.
Glisic, B., Mihaljevic, I., Popovic, M., Zaja, R., Loncar, J., Fent, K., Kovacevic, R., Smital, T. (2015) Characterization of glutathione-S-transferases in zebrafish (Danio rerio). Aquat. Toxicol. 158: 50-62.
Lončar, J., Popović, M., Krznar, P., Zaja, R., Smital, T. (2016) The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio). Sci. Rep. 6: 28937, DOI: 10.1038/srep28937.
Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2016) Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio). BMC Genomics, 17: 626, DOI 10.1186/s12864-016-2981-y.
Zaja, R., Popović, M., Lončar, J., Smital, T. (2016) Functional characterization of rainbow trout (Oncorhynchus mykiss) Abcg2a (Bcrp) transporter. Comp. Biochem. Physiol. C, 190, 15-23.
Mihaljević, I., Popović, M., Žaja, R., Maraković, N., Šinko, G., Smital, T. (2017) Interaction between the zebrafish (Danio rerio) organic cation transporter 1 (Oct1) and endo- and xenobiotics. Aquat. Toxicol. 187: 18-28.
Marić, P., Ahel, M., Senta, I., Terzić, S., Mikac, I, Žuljević, A., Smital, T. (2017) Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia. Chemosphere 174: 643-654.
Dragojević, J., Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2017) In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e. Toxicol In Vitro 46: 246-256.
Terzić, S., Udikovic-Kolić, N., Jurina, T., Krizman-Matašica, I., Senta, I., Mihaljević, I., Lončar, J., Smital, T., Ahel, M. (2018) Biotransformation of macrolide antibiotics using enriched activated sludge culture: Kinetics, transformation routes and ecotoxicological evaluation. J. Haz. Mat. 349: 143-152.
Lončar, J., Smital, T. (2018) Interaction of environmental contaminants with zebrafish (Danio rerio) multidrug and toxin extrusion protein 7 (Mate7/Slc47a7). Aquat. Toxicol. 205: 193-203.
Dean Karaica, Davorka Breljak, Jovica Lončar, Mila Lovrić, Vedran Micek, Ivana Vrhovac Madunić, Hrvoje Brzica, Carol M. Herak-Kramberger, Jana Ivković Dupor, Marija Ljubojević, Tvrtko Smital, Željka Vogrinc, Gerhard Burckhardt, Birgitta C. Burckhardt, Ivan Sabolić (2018) Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys. Arh. Hig. Rada Toksikol. 69: 286-303
Kostanjevecki, P., Petric, I., Loncar, J., Smital, T., Ahel, M., Terzic, S. (2019) Biodegradation study of methadone by adapted activated sludge: elimination kinetics, transformation products and ecotoxicological evaluation. Chemosphere 214: 719-728.
Bašica, B., Mihaljević, I., Maraković, N., Kovačević, R., Smital, T. (2019) Molecular characterization of zebrafish Gstr1, the only member of teleost-specific glutathione S- transferase class. Aquat. Toxicol. 208: 196-207.
Kostanjevecki, P., Petric, I., Loncar, J., Smital, T., Ahel, M., Terzic, S. (2019) Aerobic biodegradation of tramadol by pre-adapted activated sludge culture: Cometabolic transformations and bacterial community changes during enrichment. Sci. Total. Environ. 687: 858-866.
Dragojević, J., Mihaljević, I., Popović, M., Smital, T. (2019) Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds. Comp. Biochem. Physiol. B 236: 110309
Mihaljević, I., Bašica, B., Maraković, N., Kovačević, R., Smital, T. (2020) Interaction of organotin compounds with three major glutathione S-transferases in zebrafish. Toxicol. In Vitro 62: 104713.
Dragojević, J., Marić, P., Lončar, J., Popović, M., Mihaljević, I., Smital, T. (2020) Environmental contaminants modulate transport activity of zebrafish organic anion transporters Oat1 and Oat3. Comp. Biochem. Physiol. C 231: 108742
Marić, P., Ahel, M., Babić, O., Simeunović, J., Smital, T. (2020) Ecotoxicological profiling of selected cyanobacterial strains using multi-endpoint effect-directed analysis. Ecotoxicology 10.1007/s10646-020-02201-8

Publikacije - prilozi u knjigama

Izvorni znanstveni rad

Smital, Tvrtko ; Ahel, Marijan | Ecotoxicological characterization of the Sava River – biomarker responses and biological assays // The Sava River. | Berlin : Heidelberg: Springer, 2015. str. 177-200
link.springer.com
Smital, Tvrtko | Acute and Chronic Effects of Emerging Contaminants // Emerging Contaminants from Industrial and Municipal Waste - Occurrence, Analysis and Effects. | Berlin: Springer, 2008. str. 154-193 . doi: 10.1007/978-3-540-74795-6_3
doilink.springer.comdoi.org
Epel, David ; Smital, Tvrtko | Multidrug-multixenobiotic transporters and their significance with respect to environmental levels of pharmaceuticals and personal care products // Pharmaceuticals and personal care products in the environment - scientific and regulatory issues. | Washington (MD): American Chemical Society (ACS) ; Oxford University Press, 2001. str. 244-263-x

Publikacije - prilozi u časopisima

Izvorni znanstveni rad

Karaica, Dean; Mihaljević, Ivan; Vujica, Lana; Bošnjak, Arvena; Dragojević, Jelena; Otten, Cecile; Babić, Nency; Lončar, Jovica; Smital, Tvrtko | Stage-dependent localization of F-actin and Na+/K+-ATPase in zebrafish embryos detected using optimized cryosectioning immunostaining protocol // Microscopy research and technique, 86 (2022), 3; 294-310. doi: 10.1002/jemt.24270
doianalyticalsciencejournals.onlinelibrary.wiley.com
Vujica, Lana; Mihaljević, Ivan; Dragojević, Jelena; Lončar, Jovica; Karaica, Dean; Dananić, Ana; Bošnjak, Arvena; Smital, Tvrtko | Functional knockout of the Oatp1d1 membrane transporter affects toxicity of diclofenac in zebrafish embryos // Aquatic toxicology, 273 (2024), 107031, 20. doi: 10.1016/j.aquatox.2024.107031
doilinkinghub.elsevier.com
Vujica, Lana; Lončar, Jovica; Mišić, Lana; Lučić, Bono; Radman, Katarina; Mihaljević, Ivan; Bertoša, Branimir; Mesarić, Josip; Horvat, Marina; Smital, Tvrtko | Environmental contaminants modulate transport activity of zebrafish (Danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a2.1) // Science of the total environment, 901 (2023), doi: 10.1016/j.scitotenv.2023.165956
doiwww.sciencedirect.com
Karaica, Dean ; Mihaljević, Ivan ; Vujica, Lana ; Bošnjak, Arvena ; Dragojević, Jelena ; Otten, Cecile ; Babić, Nency ; Lončar, Jovica ; Smital, Tvrtko | Stage‐dependent localization of F‐actin and <scp> Na <sup>+</sup> /K <sup>+</sup> </scp> ‐ <scp>ATPase</scp> in zebrafish embryos detected using optimized cryosectioning immunostaining protocol // Microscopy research and technique, 2022 (2022), 1-17. doi: 10.1002/jemt.24270
doipubmed.ncbi.nlm.nih.govanalyticalsciencejournals.onlinelibrary.wiley.com
Frleta, Roberta ; Popović, Marijana ; Smital, Tvrtko ; Šimat, Vida | Comparison of Growth and Chemical Profile of Diatom Skeletonema grevillei in Bioreactor and Incubation-Shaking Cabinet in Two Growth Phases // Marine drugs, 20 (2022), 11; 697, 16. doi: 10.3390/md20110697
doiwww.mdpi.com
Marić, Petra ; Ahel, Marijan ; Maraković, Nikola ; Lončar, Jovica ; Mihaljević, Ivan ; Smital, Tvrtko | Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter // Chemosphere, 283 (2021), 131155, 12. doi: 10.1016/j.chemosphere.2021.131155
doiwww.sciencedirect.comdoi.org
Dragojević, Jelena ; Marakovic, Nikola ; Popović, Marta ; Smital, Tvrtko | Zebrafish (Danio rerio) Oatp2b1 as a functional ortholog of the human OATP2B1 transporter // Fish physiology and biochemistry, 47 (2021), 6; 1837-1849. doi: 10.1007/s10695-021-01015-7
doiwww.scopus.com
Dragojević, Jelena ; Marić, Petra ; Lončar, Jovica ; Popović, Marta ; Mihaljević, Ivan ; Smital, Tvrtko | Environmental contaminants modulate transport activity of zebrafish organic anion transporters Oat1 and Oat3 // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 231 (2020), 108742, 8. doi: 10.1016/j.cbpc.2020.108742
doiwww.sciencedirect.comdoi.org
Mihaljević, Ivan ; Bašica, Branka ; Maraković, Nikola ; Kovačević, Radmila ; Smital, Tvrtko | Interaction of organotin compounds with three major glutathione S-transferases in zebrafish // Toxicology in vitro, 62 (2020), 104713, 9. doi: 10.1016/j.tiv.2019.104713
doiwww.sciencedirect.comdoi.org
Marić, Petra ; Ahel, Marijan ; Babić, Olivera ; Simeunović, Jelica ; Smital, Tvrtko | Ecotoxicological profiling of selected cyanobacterial strains using multi-endpoint effect-directed analysis // Ecotoxicology, 2020 (2020), s10646-020-02201-8, 16. doi: 10.1007/s10646-020-02201-8
doidoi.orglink.springer.comlink.springer.com
Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Smital, Tvrtko | Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds // Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 236 (2019), 110309, 11. doi: 10.1016/j.cbpb.2019.110309
doiwww.sciencedirect.comdoi.org
Kostanjevečki, Petra ; Petrić, Ines ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Aerobic biodegradation of tramadol by pre- adapted activated sludge culture: Cometabolic transformations and bacterial community changes during enrichment // Science of the total environment, 687 (2019), 858-866. doi: 10.1016/j.scitotenv.2019.06.118
doiwww.sciencedirect.comdoi.org
Bašica, Branka ; Mihaljević, Ivan ; Maraković, Nikola ; Kovačević, Radmila ; Smital, Tvrtko | Molecular characterization of zebrafish Gstr1, the only member of teleost-specific glutathione S- transferase class // Aquatic toxicology, 208 (2019), 196-207. doi: 10.1016/j.aquatox.2019.01.005
doiwww.sciencedirect.com
Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Lovrić, Mila ; Micek, Vedran ; Vrhovac Madunić, Ivana ; Brzica, Hrvoje ; Herak-Kramberger, Carol Mirna ; Ivković Dupor, Jana ; Ljubojević, Marija et al. | Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys // Arhiv za higijenu rada i toksikologiju, 69 (2018), 4; 286-303. doi: 10.2478/aiht-2018-69-3157
doihrcak.srce.hr
Kostanjevečki, Petra ; Sviličić Petrić, Ines ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Biodegradation study of methadone by adapted activated sludge: Elimination kinetics, transformation products and ecotoxicological evaluation // Chemosphere, 214 (2019), 719-728. doi: 10.1016/j.chemosphere.2018.09.153
doiwww.sciencedirect.comdoi.org
Terzić, Senka ; Udiković-Kolić, Nikolina ; Jurina, Tamara ; Krizman-Matasić, Ivona ; Senta, Ivan ; Mihaljević, Ivan ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan | Biotransformation of macrolide antibiotics using enriched activated sludge culture: Kinetics, transformation routes and ecotoxicological evaluation // Journal of hazardous materials, 349 (2018), 143-152. doi: 10.1016/j.jhazmat.2018.01.055
doiwww.sciencedirect.com
Lončar, Jovica ; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish multidrug and toxin extrusion protein 7 (Mate7/Slc47a7) // Aquatic toxicology, 205 (2018), 193-203. doi: 10.1016/j.aquatox.2018.10.016
doidoi.org
Marić, Petra ; Ahel, Marijan ; Senta, Ivan ; Terzić, Senka ; Mikac, Iva ; Žuljević, Ante ; Smital, Tvrtko | Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia // Chemosphere, 174 (2017), 643-654. doi: 10.1016/j.chemosphere.2017.02.007
doiwww.sciencedirect.com
Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Šinko, Goran ; Smital, Tvrtko | Interaction between zebrafish Oct1 and endo- and xenobiotics // Aquatic toxicology, 187 (2017), 18-28. doi: 10.1016/j.aquatox.2017.03.012
doiwww.sciencedirect.comdx.doi.org
Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e // Toxicology in vitro, 46 (2017), 246-256. doi: 10.1016/j.tiv.2017.09.026
doiwww.sciencedirect.com
Žaja, Roko ; Popović, Marta ; Lončar, Jovica ; Smital, Tvrtko | Functional characterization of rainbow trout (Oncorhynchus mykiss) Abcg2a (Bcrp) transporter // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 190 (2016), 15-23. doi: 10.1016/j.cbpc.2016.07.005
doiwww.sciencedirect.com
Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio) // Bmc genomics, 17 (2016), 626-1-626-13. doi: 10.1186/s12864-016-2981-y
doibmcgenomics.biomedcentral.com
Lončar, Jovica ; Popović, Marta ; Krznar, Petra ; Žaja, Roko ; Smital, Tvrtko | The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio) // Scientific reports, 6 (2016), 28937, 15. doi: 10.1038/srep28937
doiwww.nature.comwww.nature.com
Glišić, Branka ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Fent, Karl ; Kovačević, Radmila ; Smital, Tvrtko | Characterization of Glutathione-S-transferases in zebrafish (Danio rerio) // Aquatic toxicology, 158 (2015), 50-62. doi: 10.1016/j.aquatox.2014.10.013
doiwww.sciencedirect.com
Ferreira, Marta ; Santosa, Pedro ; Rey-Salgueiroa, Ledicia ; Žaja, Roko ; Reis-Henriques, Maria Armanda ; Smital, Tvrtko | The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European Seabass (Dicentrarchus labrax) primary hepatocytes // Chemosphere, 100 (2014), 152-159. doi: 10.1016/j.chemosphere.2013.11.051
doiwww.sciencedirect.com
Traven, Luka ; Mićović, Vladimir ; Vukić Lušić, Darija ; Smital, Tvrtko | The responses of the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity in sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a polluted site: implications for their use in environm // Environmental monitoring and assessment, 185 (2013), 11; 9009-9018. doi: 10.1007/s10661-013-3230-3
doilink.springer.com
Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish uptake transporter Oatp1d1 (Slco1d1) // Toxicology and applied pharmacology, 280 (2014), 149-158. doi: 10.1016/j.taap.2014.07.015
doidx.doi.org
Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel Organic anion transporting polypeptide // The Journal of biological chemistry, 288 (2013), 47; 33894-33911. doi: 10.1074/jbc.M113.518506
doiwww.jbc.orgwww.jbc.org
Bošnjak, Ivana ; Zaja, Roko ; Sauerborn Klobučar, Roberta ; Šver, Lidija ; Franekić, Jasna ; Smital, Tvrtko | Identification of ABC Transporter Genes in Gonad Tissue of two Mediterranean Sea Urchin Species: Black, Arbacia lixula L., and Rocky, Paracentrotus lividus L. // Bulletin of environmental contamination and toxicology, 91 (2013), 4; 415-419. doi: 10.1007/s00128-013-1021-8
doilink.springer.com
Zaja, Roko ; Terzić, Senka ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Ahel, Marijan ; Smital, Tvrtko | Identification of P-Glycoprotein Inhibitors in Contaminated Freshwater Sediments // Environmental science & technology, 47 (2013), 9; 4813-4821. doi: 10.1021/es400334t
doipubs.acs.org
Ahel, Marijan ; Mikac, Nevenka ; Smital, Tvrtko | Water resources and wastewater management in the Sava River Basin // Danube News, 13 (2011), 24; 13-15
www.iad.gs
Smital, Tvrtko ; Terzić, Senka ; Lončar, Jovica ; Senta, Ivan ; Žaja, Roko ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut-Erik ; Thomas, Kevin V. ; Ahel, Marijan | Prioritisation of organic contaminants in a river basin using chemical analyses and bioassays // Environmental science and pollution research, 20 (2013), 3; 1384-1395. doi: 10.1007/s11356-012-1059-x
doird.springer.comlink.springer.com
Della Torre, Camilla ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Focardi, Silvano ; Corsi, Ilaria | Interaction of ABC transport proteins with toxic metals at the level of gene and transport activity in the PLHC-1 fish cell line // Chemico-biological interactions, 198 (2012), 1/3; 9-17. doi: 10.1016/j.cbi.2012.04.008
doiwww.sciencedirect.com
Reifferscheid, Georg ; Maes, Hanna ; Allner, Bernhard ; Badurova, Jana ; Belkin, Shimshon ; Blum, Kerstin ; Brauer, Frank ; Bressling, Jana ; Domeneghetti, Stefania ; Elad, Tal et al. | International round-robin study on the Ames fluctuation test // Environmental and molecular mutagenesis, 53 (2012), 3; 185-197. doi: 10.1002/em.21677
doionlinelibrary.wiley.com
Fischer, Stephan ; Lončar, Jovica ; Žaja, Roko ; Schnell, Sabine ; Schirmer, Kristin ; Smital, Tvrtko ; Luckenbach, Till | Constitutive mRNAexpression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss) // Aquatic toxicology, 101 (2011), 2; 438-446. doi: 10.1016/j.aquatox.2010.11.010
doiwww.sciencedirect.comdoi.org
Žaja, Roko ; Lončar, Jovica ; Popović, Marta ; Smital, Tvrtko | First characterisation of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line // Aquatic toxicology, 103 (2011), 1/2; 53-62. doi: 10.1016/j.aquatox.2011.02.005
doiwww.sciencedirect.comdoi.org
Smital, Tvrtko ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Pivčević, Branka ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin. V. ; Ahel, Marijan | Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays // Ecotoxicology and environmental safety, 74 (2011), 4; 844-851. doi: 10.1016/j.ecoenv.2010.11.010
doiwww.sciencedirect.comdoi.org
Sauerborn Klobučar, Roberta ; Žaja, Roko ; Franjević, Damjan ; Brozović, Anamaria ; Smital, Tvrtko | Presence of Ecotoxicologically Relevant Pgp- and MRP- Transcripts and Proteins in Cyprinid Fish // Arhiv za higijenu rada i toksikologiju, 61 (2010), 2; 175-181
hrcak.srce.hrhrcak.srce.hr
Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): phylogenetic analysis and tissue distribution // Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 155 (2010), 3; 327-335. doi: 10.1016/j.cbpa.2009.11.011
doidoi.orgwww.sciencedirect.com
Lončar, Jovica ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss) // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 151 (2010), 2; 209-215. doi: 10.1016/j.cbpc.2009.10.009
doiwww.sciencedirect.comdoi.org
Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko | A novel ABC transporter: the first insight into zebrafish (Danio rerio) Abch1 // Marine environmental research, 69 (2010), S1; S11-S13. doi: 10.1016/j.marenvres.2009.10.016
doiwww.sciencedirect.comwww.sciencedirect.com
Bošnjak, Ivana ; Šegvić, Tanja ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Mladineo, Ivona | Sea Urchin Embryotoxicity Test for Determination of Environmental Contaminants–Potential Role of the MRP Proteins // Water, air and soil pollution, 217 (2011), 1-4; 627-636. doi: 10.1007/s11270-010-0615-6
doilink.springer.comdoi.org
Traven, Luka ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Mićović, Vladimir | CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – In vitro evaluation using the PLHC-1 fish hepatoma cell line // Toxicology in vitro, 22 (2008), 6; 1648-1656. doi: 10.1016/j.tiv.2008.06.012
doiwww.sciencedirect.comwww.sciencedirect.com
Bošnjak, Ivana ; Uhlinger, Kevin R. ; Heim, Wesley ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Coale, Kenneth ; Epel, David ; Hamdoun, Amro | Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not Organic, Mercury in Sea Urchin Embryos // Environmental science & technology, 43 (2009), 21; 8374-8380. doi: 10.1021/es901677r
doipubs.acs.org
Epel, David ; Stevenson, Charlotte N. ; MacManus-Spencer, Laura A. ; Luckenbach, Till ; Hamdoun, Amro ; Smital, Tvrtko | Efflux transporters: newly appreciated roles in protection against pollutants // Environmental science & technology, 42 (2008), 11; 3914-3920. doi: 10.1021/es087187v
doipubs.acs.orgdoi.org
Žaja, Roko ; Munić, Vesna ; Sauerborn Klobučar, Roberta ; Ambriović-Ristov, Andreja ; Smital, Tvrtko | Cloning and molecular characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes // Aquatic toxicology, 90 (2008), 4; 322-332
Žaja, Roko ; Caminada, Daniel ; Lončar, Jovica ; Fent, Karl ; Smital, Tvrtko | Development and characterization of P-glycoprotein 1 (Pgp1 ; ABCB1) mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line // Toxicology and applied pharmacology, 227 (2008), 2; 207-218. doi: 10.1016/j.taap.2007.11.001
doiwww.sciencedirect.comwww.sciencedirect.com
Källqvist, Torsten ; Milačič, Radmila ; Smital, Tvrtko ; Thomas, Kevin V ; Vranes, Sanja ; Tollefsen, Knut-Erik | Chronic toxicity of the Sava River (SE Europe) sediments and river water to the algae Pseudokirchneriella subcapitata // Water research, 42 (2007), 8-9; 2146-2156. doi: 10.1016/j.watres.2007.11.026
doiwww.sciencedirect.com
Žaja, Roko ; Munić, Vesna ; Smital, Tvrtko | Cloning and mRNA expression analysis of an ABCG2 (BCRP) efflux transporter in rainbow trout (Oncorhynchus mykiss) liver and primary hepatocytes // Marine environmental research, 66 (2008), 1; 77-79. doi: 10.1016/j.marenvres.2008.02.028
doiwww.sciencedirect.comdoi.org
Žaja, Roko ; Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line // Aquatic toxicology, 81 (2007), 365-376
Žaja, Roko ; Klobučar, Goran I.V. ; Sauerborn Klobučar, Roberta ; Hackenberger, Branimir K. ; Smital, Tvrtko | Haemolymph as compartment for efficient and non-destructive determination of Pgp mediated MXR activity in bivalves // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 143 (2006), 1; 103-112-x
Smital, Tvrtko ; Luckenbach, Till ; Sauerborn, Roberta ; Hamdoun, M. Amro ; Vega, L. Rebecca ; Epel, David | Emerging contaminants - pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms // Mutation research, 552 (2004), 101-117-x
Pivčević, Branka ; Sauerborn Klobučar, Roberta ; Krča, Sanja ; Žaja, Roko ; Jelaska, Dalibor ; Smital, Tvrtko ; Britvić Smiljana | Methods of molecular biology in ecotoxicological research // Periodicum biologorum, 106 (2004), 2; 121-125-x
Sauerborn, Roberta ; Stupin Polancec, Darija ; Zaja, Roko ; Smital, Tvrtko | Identification of the multidrug resistance-associated protein (mrp) related gene in red mullet (Mullus barbatus) // Marine environmental research, 58 (2004), 2-5; 199-204. doi: 10.1016/j.marenvres.2004.03.120
doidx.doi.orgwww.sciencedirect.com
Smital, Tvrtko ; Sauerborn, Roberta ; Hackenberger, Branimir | Inducibility of the multixenobiotic resistance mechanism (MXR) transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha // Aquatic toxicology, 65 (2003), 443-465-x
Smital, Tvrtko ; Sauerborn, Roberta | Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio // Marine environmental research, 54 (2002), 3/5; 449-453. doi: 10.1016/S0141-1136(02)00155-1
doiwww.sciencedirect.comwww.sciencedirect.com
Ramljak, Sanja ; Hackenberger, Branimir ; Smital, Tvrtko ; Britvić, Smiljana | Evaluation of the genotoxic and cytochrome P450 monooxigenase-inhibitory potential of Dicuran on procaryotic and eucaryotic test systems // Journal of environmental science and health. Part B, 35 (2000), 6; 751-770
Smital, Tvrtko ; Sauerborn, Roberta ; Pivčević, Branka ; Krča, Sanja ; Kurelec, Branko | Interspecies differences in P-glycoprotein mediated activity of multixenobiotic resistance mechanism in several marine and freshwater invertebrates // Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 126 (2000), 2; 175-186. doi: 10.1016/s0742-8413(00)00110-9
doiwww.sciencedirect.com
Kurelec, Branko ; Britvić, Smiljana ; Pivčević, Branka ; Smital, Tvrtko | Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment // Marine environmental research, 46 (1998), 1-5; 415-419-x. doi: 10.1016/S0141-1136(97)00065-2
doiwww.sciencedirect.com
Smital, Tvrtko ; Kurelec, Branko | The activity of multixenobiotic resistance mechanism determined by rhodamine B-efflux method as a biomarker of exposure // Marine environmental research, 46 (1998), 1-5; 443-447-x. doi: 10.1016/S0141-1136(97)00087-1
doiwww.sciencedirect.com
Osmak, Maja ; Brozović, Anamaria ; Ambriović-Ristov, Andreja ; Hadžija, Mirko ; Pivčević, Branka ; Smital, Tvrtko | Inhibition of apoptosis is the cause of resistance to doxorubicin in human breast adenocarcinoma cells // Neoplasma, 45 (1998), 4; 223-230
www.ncbi.nlm.nih.gov
Smital, Tvrtko ; Kurelec, Branko | The concentrations of inhibitors of multixenobiotic resistance mechanism in natural waters: The direct in vivo demonstration of their effect // Environmental toxicology and chemistry, 16 (1997), 10; 2164-2170-x
Smital, Tvrtko ; Pivčević, Branka ; Kurelec, Branko | Reversal of multidrug resistance by extract from a marine algae Caulerpa taxifolia // Periodicum biologorum, 98 (1996), 2; 197-203

Pregledni rad (znanstveni)

Kurelec, Branko ; Smital, Tvrtko ; Britvić, Smiljana ; Pivčević, Branka ; Krča, Sanja ; Jelaska, Dalibor ; Balen, Sofija ; Sauerborn, Roberta ; Mustajbegović, Suada | Multixenobiotic resistance mechanism in aquatic organisms // Periodicum biologorum, 99 (1997), 3; 319-328

Ostalo

Smital, Tvrtko ; Kurelec, Branko | The chemosenzitizers of multixenobiotic resistance mechanism in aquatic invertebrates : a new class of pollutants // Mutation research. Fundamental and molecular mechanisms of mutagenesis, 399 (1998), 1; 43-53-x. doi: 10.1016/S0027-5107(97)00265-0
doiwww.sciencedirect.com

Prethodno priopćenje

Kurelec, Branko ; Smital, Tvrtko ; Pivčević, Branka ; Eufemia, Nancy ; Epel, David | Multixenobiotic resistance, P-glycoprotein, and chemosensitizers // Ecotoxicology, 9 (2000), 5; 307-327-x
www.springerlink.com

Stručni rad

Smital, Tvrtko ; Lončar, Jovica ; Bakran-Petricioli, Tatjana ; Petricioli, Donat | Pregled recentnih istraživanja usmjerenih određivanju ekotoksikološkog učinka proizvodnih plinskih platformi u sjevernom Jadranu // Naftaplin = Nafta i plin, 36 (2016), 145-146; 89-102
Bakran-Petricioli, Tatjana ; Smital, Tvrtko ; Petricioli, Donat ; Mlinarić, Damir | Obraštaj na plinskim platformama u Jadranu kao pokazatelj stanja okoliša // Naftaplin = Nafta i plin, 35 (2015), 142; 72-80
bib.irb.hr

Prikaz, osvrt, kritika

Smital, Tvrtko | Physiological adaptations of animals in the aquatic environment By Čedomil Lucu // Periodicum biologorum, 116 (2014), 3; 331-333
hrcak.srce.hr

Pregledni rad (stručni)

Ahel, Marijan ; Antičić, Tome ; Balog, Tihomir ; Bilić, Nevenko ; Guberina, Branko ; Katušić Hećimović, Silva ; Jerić, Ivanka ; Klanjšček, Tin ; Legović, Tarzan ; Musić, Svetozar et al. | The Ruder Boskovic Institute – Today and Tomorrow // Periodicum biologorum, 112 (2010), 4; 369-374
hrcak.srce.hr

Publikacije - prilozi sa skupa (u zborniku)

Sažetak izlaganja sa skupa

Bakija Alempijević, Saranda; Mihaljević, Ivan; Dragojević, Jelena; Smital, Tvrtko; Frka, Sanja; Strmečki Kos, Slađana | The impact of nitrated monoaromatic hydrocarbons from atmospheric aerosols on different levels of biological organisation in aquatic systems // 8th Faculty of Science PhD Student Symposium: Book of Abstracts / Posarić, Laura; Gmižić, Daria; Ostojić, Tea et al. (ur.). | Zagreb: Faculty of Science, University of Zagreb, Zagreb, Croatia, 2024. str. 48-48
drive.google.com
Ivanković, Klaudija ; Dragojević, Jelena ; Mihaljević, Ivan ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Kinetics of uptake and elimination of complex drug mixture in zebrafish (Danio rerio) // Abstract book of SETAC Europe 33rd Annual Meeting “Data-driven environmental decision-making”. | Dublin: Society of Environmental Toxicology and Chemistry (SETAC), 2023. str. 274-274
Karaica, Dean ; Mihaljević, Ivan ; Vujica, Lana ; Dragojević, Jelena ; Lončarić, Nora ; Bošnjak, Arvena ; Otten, Cecile ; Lončar, Jovica ; Smital, Tvrtko | Optimized protocol for whole-mount immunohistochemistry in zebrafish embryos (Danio rerio) // Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2022. str. 90-90
congress2022.hdbmb.hrcongress2022.hdbmb.hr
Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Frka, Sanja ; Smital, Tvrtko ; Strmečki Kos, Slađana | Kvantifikacija i ekotoksikologija nitro-monoaromatskih ugljikovodika u atmosferskim lebdećim česticama PM10 izgaranja biomase // Znanstvena škola o okolišu 2022: Multidisciplinarni pristup istraživanju mikro- i nano- čestica u prirodnim sustavima : knjiga sažetaka. | Zagreb, 2022. str. 6-6
znanskola2022.com.hr
Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Dragojević, Jelena ; Frka, Sanja ; Smital, Tvrtko ; Strmečki Kos, Slađana | Exploring ecotoxicological effects of nitromonoaromatic compounds by in vitro and in vivo bioassays / Ispitivanje ekotoksičnih učinaka nitromonoaromatskih spojeva in vitro i in vivo biotestovima // 6. Simpozij studenata doktorskih studija PMF-a : Knjiga sažetaka = 6th Faculty of Science PhD Student Syposium : Book of Abstracts. | Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2022. str. 300-301
www.pmf.unizg.hr
Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Dragojević, Jelena ; Strmečki Kos, Slađana ; Frka, Sanja ; Smital, Tvrtko | Ekotoksični učinci metil-nitrokatehola // Znanstvena škola o okolišu 2021: Sveobuhvatni pristup istraživanju antropogenih pritisaka na okoliš : knjiga sažetaka. | Zagreb, 2022. str. 9-9
znanskola2021.com.hr
Bakija Alempijević, Saranda ; Mihaljević, Ivan ; Dragojević, Jelena ; Strmečki Kos, Slađana ; Frka, Sanja ; Smital, Tvrtko | Ecotoxicological Effects of Methylnitrocatechols // 21st European Meeting on Environmental Chemistry : Book of Abstracts. | Beograd: Serbian Chemical Society, 2021. str. 161-161
emec21.rs
Miloloža, Martina ; Bule, Kristina ; Cvetnić, Matija ; Ukić, Šime ; Markić, Marinko ; Bolanča, Tomislav ; Ocelić Bulatović, Vesna ; Dragojević, Jelena ; Smital, Tvrtko ; Kučić Grgić, Dajana | Ispitivanje toksičnosti mikroplastike na Chlorellu sp., Pseudomonas putidu i Danio rerio // 18. Ružičkini dani: Danas znanost – sutra indistrija. | Zagreb : Osijek: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Prehrambeno tehnološki fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku, 2020. str. 152-152
www.hdki.hr
Pivčević, Branka ; Maltar Tanja ; Smital, Tvrtko | Određivanje estrogenosti uzoraka priobalne vode Jadranskog mora i vode iz pročišćivača miješanih otpadnih voda upotrebom YES (“yeast estrogen screen”) biotesta // 9th Croatian Biological Congress with International Participation. | 2006. str. 350-351
Katalinić, Maja ; Lončar, Jovica ; Miš, Katarina ; Vrhovac Madunić, Ivana ; Smital, Tvrtko ; Pirkmajer, Sergej | Human muscle cells as a model to study the expression and physiological role of the NRE enzyme // 44th FEBS Congress. | Krakov, 2019, P25001, 1
2019.febscongress.org2019.febscongress.org
Terzić, Senka ; Kostanjevečki, Petra ; Krizman Matasić, Ivona ; Senta, Ivan ; Jurina, Tamara ; Udiković-Kolić, Nikolina ; Ćurko, Josip ; Matošić, Marin ; Lončar, Jovica ; Mihaljević, Ivan et al. | Evaluation of macrolide antibiotic transformation in model biodegradation and ozonation experiments using target and non-target analyses and ecotoxicological bioassays // SETAC Europe 28th Annual Meeting : Abstract Book. | Bruxelles: ociety of Environmental Toxicology and Chemistry Europe, 2018. str. 19-19
www.setac.org
Dragojević, Jelena ; Mihaljević, Ivan ; Smital, Tvrtko | Interaction of zebrafish (Danio rerio) organic anion transporter 2d (Oat2d) with xeno- and endobiotics // 10th Congress of Toxicology in Developing Countries : book of abstracts. | Beograd: Serbian Society of Toxicology, 2018. str. 135-136
dais.sanu.ac.rs
Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Smital, Tvrtko | Characterization of zebrafish (Danio rerio) organic anion transporters Oat1 and Oat3 // 2nd International FishMed Conference on Zebrafish Research : Abstract Book. | Varšava: International Institute of Molecular and Cell Biology in Warsaw, 2018. str. 60-60
Dragojević, Jelena ; Mihaljević, Ivan ; Marić, Petra ; Popović, Marta ; Smital, Tvrtko | Interaction of zebrafish Organic anion transporters (Oats) with endo- and xenobiotics // Workshop "Cyanotoxins - Toxicity, Health and Environmental Impact" : Programme and abstracts. | Novi Sad: Faculty of Sciences, 2017. str. 31-31
Dragojević, Jelena ; Mihaljević, Ivan ; Smital, Tvrtko | Functional characterization of zebrafish (Danio rerio) organic anion transporter 2d (Oat2d) // Book of abstracts of 10th European Zebrafish Meeting. | 2017. str. 572-572
Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Smital, Tvrtko | Determining the type of interaction between zebrafish Oct1 and endo- and xenobiotics // Abstract Book - International FishMed Conference on Zebrafish Research. | Varšava: International Institute of Molecular and Cell Biology in Warsaw, 2016. str. 64-64
Smital, Tvrtko ; Hamer, Bojan ; Bakran-Petricioli, Tatjana ; Petricioli, Donat ; Mlinarić, Damir | Current practices in environmental impact assessment of drilling and gas exploitation activities in the Croatian part of the Adriatic Sea // Knjiga sažetaka s 8th International Oil & Gas Conference and Exhibition (Šibenik, Hrvatska, 13. - 16. 10. 2015.). | Zagreb: Hrvatska udruga naftnih inženjera i geologa (HUNIG), 2015. str. 191-192
Lončar, Jovica ; Krznar, Petra ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | First characterization of Multidrug and Toxin Extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 168-168
Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Smital, Tvrtko | Characterization of organic cation transporters in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 61-61
Marić, Petra ; Mihaljević, Ivan ; Lončar, Jovica ; Dragojević , Jelena ; Smital, Tvrtko | Interactions of secondary metabolites from cyanobacteria and invasive tropical algae with the cellular detoxification mechanism in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 176-176
Mihaljević, Ivan ; Glisić, Branka ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Fent, Karl ; Kovačević Radmila ; Smital, Tvrtko | Characterization of glutathione-S-transferases in zebrafish (Danio rerio) // Molecules of Life - FEBS3+ Meeting. | Ljubljana: Slovenian Biochemical Society, 2015. str. 180-180
Smital, Tvrtko ; Mihaljević, Ivan ; Lončar, Jovica ; Popović, Marta ; Žaja, Roko | Functional characterization of MATE (SLC47A) and OCT (SLC22A) transporters in zebrafish (Danio rerio) // PRIMO 18 - 18th International symposium on Pollutant Responses in Marine Organisms. | Trondheim: University of Trondheim, Norway, 2015. str. 119-119
Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Ljubojević, Marija ; Carol Herak Kramberger ; Micek, Vedran ; Vrhovac, Ivana ; Ivković Dupor, Jana ; Mihaljević, Ivan ; Marić, Petra et al. | Chloride formate exchanger (CFEX - slc26a6) in rat organs ; sex-dependent expression in kidneys // Book of Abstracts of the FEBS3+Meeting “Molecules of Life”. | Ljubljana: Slovenian Biochemical Society, 2015. str. 28-28
Lončar, Jovica ; Fischer, Stephan ; Žaja, Roko ; Wellner, Peggy ; Luckenbach, Till ; Schirmer, Kristin ; Smital, Tvrtko | Gene expression and functional analysis of toxicologically important ABC transporters in rainbow trout (Oncorhynchus mykiss) tissues and cell lines // ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases. | Beč, 2010. str. 162-162
Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Mihaljević, Ivan ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković, Jana ; Burckhardt, Birgitta et al. | Immunolocalization of chloride-formate exchanger (Slc26a6) in various rat tissues ; sex-dependent expression in kidneys // Experimental animals in scientific research. | Zagreb, 2014. str. 56-57
Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković, Jana ; Mihaljević, Ivan ; Marić, Petra et al. | Cell localization and sex-dependent expression of chloride/formate exchanger CFEX (Slc26a6) in rat kidneys // The Interplay of Biomolecules. | Zagreb: Hrvatsko Društvo za Biotehnologiju, 2014. str. 100-100
Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | First insight into non-mammalian SLCs: functional characterization of zebrafish (Danio rerio) uptake transporters (Solute Carrier families SLC21 and SLC22) // The EMBO Meeting 2011. | Beč, 2011. str. 139-139
Ahel, Marijan ; Terzić, Senka ; Lončar, Jovica ; Mikac, Iva ; Žaja, Roko ; Senta, Ivan ; Popović, Marta ; Sauerborn Klobučar, Roberta ; Tollefsen, Knut-Erik ; Thomas, Kevin V et al. | Effects-directed Analysis of Contaminated Sediments from the Sava River, Croatia // Ecosystem Protection in a Sustainable World: A Challenge for Science and Regulation. | Milano: Society of Environmental Toxicology and Chemistry (SETAC), Europe Office, 2011. str. 31-31
Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin V ; Smital, Tvrtko | Prioritization of hazardous chemical contaminants in the Sava River basin using EDA approach // Characterization of hazardous chemical contamination-from environmental chemistry and toxicology to risk assessment. | Zagreb: Institute Ruđer Bošković, 2010. str. 20-20
Loncar, Jovica ; Fischer, Stephan ; Zaja, Roko ; Wellner, Peggy ; Luckenbach, Till ; Schirmer, Kristin ; Smital, Tvrtko | Gene expression and functional analysis of toxicologically important ABC transporters in rainbow trout (Oncorhynchus mykiss) tissues and cell lines // ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Disease: Abstract Book. | Innsbruck: Federation of European Biochemical Societies (FEBS), 2010. str. 162-162
Smital, Tvrtko ; Terzić, Senka ; Žaja, Roko ; Lončar, Jovica ; Mikac, Iva ; Popović, Marta ; Senta, Ivan ; Ahel, Marijan | Effect-directed analyses of hazardous chemical contaminants in freshwater sediments impacted by industrial effluents // Science and Technology for Environmental Protection: Book of Abstracts. | Sevilla: Society of Environmental Toxicology and Chemistry (SETAC), Europe Office, 2010. str. 139-139
Lončar, Jovica ; Popovic, Marta ; Caminada, Daniel ; Fent, Karl ; Smital, Tvrtko | Development and characterization of the P- glycoprotein 1 (Pgp1 ; ABCB1) mediated doxorubicin-reistant PLHC-1 hepatoma fish cell line // TP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases: Book of Abstracts. | Innsbruck: Federation of European Biochemical Societies (FEBS), 2008. str. 131-131
Lončar, Jovica ; Žaja, Roko ; Ahel, Marijan ; Smital, Tvrtko | Ekotoksikološka karakterizacija otpadnih voda Erod biotestom (PLHC-1 stanična linija) i testom toksičnosti na algama (Pseudokirchneriella subcapitata). // Zbornik sažetaka. | Rovinj: HDB 1885, 2006. str. 358-359
Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Mjerenje genotoksičnog učinka Ames testom u XAD-7 koncentratima morske vode Sjevernog, Srednjeg i Južnog Jadrana // 11. stručni sastanak laboratorija ovlaštenih za ispitivanje voda. | 2010. str. 61-63
Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Ames versus Ames II assay - genotoxicity assessment of environmental samples // NATO SfP 982590 project workshop: Characterisation of hazardous chemical contamination – from environmental chemistry and toxicology to risk assessment. | Zagreb: IRB, Zagreb, 2010. str. 38-38
Hamer, Bojan; Jakšić, Željko; Vucelić, Vedran; Krča, Sanja; Smital, Tvrtko; Reifferscheid, Georg; Smodlaka, Nenad; Batel, Renato | Temporal and Spatial variations of Seawater Genotoxicity, Mutagenicity and mussel DNA integrity along the Adriatic coast, Croatia: A long term study - "Project Adriatic" (1998-2007) // 14th International Symposium on Toxicity Assessment - Program and abstract book. | Metz, 2009. str. 103-103
Terzić, Senka ; Lončar, Jovica ; Mikac, Iva ; Popović, Marta ; Senta, Ivan ; Žaja, Roko ; Smital, Tvrtko ; Ahel, Marijan | Assessment of hazardous organic contamination in freshwater sediments impacted by industrial effluents // The First Joint PSE-SETAC Conference on Ecotoxicology - Ecotoxicology in the real world : Book of abstracts. | Krakov, 2009. str. 51-51
Ahel, Marijan ; Lončar, Jovica ; Mikac, Iva ; Popović, Marta ; Senta, Ivan ; Terzić, Senka ; Žaja, Roko ; Tollefsen, Knut-Erik ; Thomas, Kevin V. ; Smital, Tvrtko | Characterization of organic contaminants in municipal wastewater of the city of Zagreb by chemical methods and bioassays // The First Joint PSE-SETAC Conference on Ecotoxicology - Ecotoxicology in the real world : Book of abstracts. | Krakov: Jagiellonian University & Polish Society of Ecotoxicology & Society of Environmental Toxicology and Chemistry - Central and Eastern Europe Branch, 2009. str. 50-50
Bošnjak, Ivana ; Uhlinger, Kevin R. ; Heim, Wesley ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Coale, Kenneth ; Epel, David ; Hamdoun, Amro | Multidrug efflux transporters limit accumulation of inorganic, but not organic, mercury in sea urchin embryos // EMBO Young Scientists Forum. | Zagreb, 2009. str. 10-10
www.bioinfo.hr
Sauerborn Klobučar, Roberta ; Krča, Sanja ; Brozović, Anamaria ; Stupin Polančec, Darija ; Žaja, Roko ; Smital, Tvrtko | Determination of the presence of P-gp- and MRP-related transcripts and proteins in cyprinid fish species // Abstracts of the 13rd International Symposyum on Pollutant Responses In Marine Organisms (PRIMO). | 2005
Bošnjak, Ivana ; Epel, David ; Johnson, Ken ; Franekić Čolić, Jasna ; Smital, Tvrtko ; Hamdoun, Amro M. | Multidrug resistance-associated protein (MRP) protects sea urchin embryos (Strongylocentrotus purpuratus) against mercuric chloride // Pollutant responses in marine organisms ; 14th International symposium. | Florianopolis: Universidade Federal de Santa Catalina, 2007. str. 126-126
Bošnjak, Ivana ; Coale, Kenneth ; Franekić Čolić, Jasna ; Smital, Tvrtko ; Epel, David ; Hamdoun, Amro | Transportna aktivnost multidrug resistance associated proteina (MRP) posreduje razlike u akumulaciji i toksičnosti anorganske i organske žive u embrijima morskih ježinaca // 50 godina molekularne biologije u Hrvatskoj - zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 81-81
Bošnjak, Ivana ; Coale, Kenneth ; Franekić Čolić, Jasna ; Smital, Tvrtko ; Epel, David ; Hamdoun, Amro | Multidrug resistance associated protein (MRP) transport activity mediates differences in susceptibility to inorganic and organic mercury in sea urchin (Strongylocentrotus purpuratus) embryos // ABC Transport Proteins in Environmental Health and Toxicology. | Siena, 2007. str. 22-22
Pivčević, Branka ; Skukan, Ivana ; Smital, Tvrtko | Elimination of MXR inhibitory pharmaceuticals from waste waters by membrane bioreactor, reversal osmosis, nanofiltration and ozonization // ABC transport proteins in environmental health and toxicology. | Siena: University of Siena, 2007
Pivčević, Branka ; Skukan, Ivana ; Lončar, Jovica ; Smital, Tvrtko | Ecotoxicological analysis of daily and weekly profile of influent and effluent waste waters of the city of Čakovec, Croatia // Emerging contaminants in wastewaters: monitoring tools and treatment technologies : 2nd EMCO workshop : Abstracts. | 2007. str. 111-111
Dražić, Marica Maja ; Bubalo, Dragan ; Smital, Tvrtko ; Krča, Sanja ; Britvić, Smilja ; Kezić, Nikola | Ekspresija mehanizma multiksenobiotičke otpornosti izlaganjem pčela aktivnim tvarima lijekova // Zbornik radova. | Osijek: Poljoprivredni fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku, 2005. str. 291-292-x
Raspor, Biserka ; Erk, Marijana ; Filipović, Vlatka ; Pavičić, Jasenka ; Jurič, Dušica ; Dragun, Zrinka ; Britvić, Smilja ; Krča, Sanja ; Pivčević, Branka ; Smital, Tvrtko et al. | An integrated environmental monitoring system for Croatian freshwater, estuarine and coastal marine areas : the CROWAT project // Abstracts of the SETAC Europe 14th Annual Meeting on Environmental Science Solutions : A Pan-European Perspective. | Prag: Society of Environmental Toxicology and Chemistry (SETAC), 2004. str. 244-244
Raspor, Biserka ; Erk, Marijana ; Filipović, Vlatka ; Pavičić, Jasenka ; Jurič, Dušica ; Dragun, Zrinka ; Britvić, Smilja ; Krča, Sanja ; Pivčević, Branka ; Smital, Tvrtko et al. | CROWAT projekt : sustav monitoringa okoliša za kopnene vode, estuarije i more u Hrvatskoj // 8. hrvatski biološki kongres s međunarodnim sudjelovanjem : Zbornik sažetaka = 8th Croatian Biological Congress with International Participation : Proceeding of abstracts. | Zagreb: Hrvatsko biološko društvo, 2003. str. 347-348
Hackenberger K., Branimir ; Britvić-Budicin, Smiljana ; Smital, Tvrtko ; Stepić, Sandra | The possible influence of some physiological parameters on EROD-activity data valuation // Risk Assessment and Management of Large Contamination Sites : Congress Proceedings. | Halle, 2002
Dražić, Marica Maja ; Smital, Tvrtko ; Britvić, Smilja ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Kezić, Nikola | EXPRESSION OF MULTIXENOBIOTIC RESISTANCE IN EUROPEAN HONEYBEE STRAINS (Apis mellifera L.) // Final Programe and Book of Abstract, XXXVIIIth APIMONDIA, International Apicultural Congress, Ljubljana, Slovenia, August 24 - 29. 2003.. | Ljubljana: APIMONDIA, 2003. str. 674-675-x
Hackenberger K., Branimir ; Smital, Tvrtko ; Britvić-Budicin, Smiljana ; Stepić, Sandra ; Pavlić, Želimira ; Klobučar I.V., Goran | Eksperimentalni organizmi u suvremenom praćenju zagađenja vodenog okoliša / Experimental organisms in modern monitoring water pollution // Prva hrvatska konferencija Hrvatskog društvo kemijskih inženjera i tehnologa - Ekoinženjerstvo 2002 : knjiga sažetaka. | Zagreb, 2002. str. 108-108
Dražić, Marica Maja ; Smital, Tvrtko ; Britvić Budicin, Smiljana ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Kezić, Nikola | Multixenobiotic resistance mechanism in honeybees // Report of the 47th seminar in Blaubeuren near Ulm Heinrich-Fabri-Insitut of the Ebergard-Karls-University Tubingen 3-5 April 2000. | Pariz: INRA/DIB-AGIB/EDPm Sciences, 2000. str. 601-601-x
Dražić, Marica Maja ; Smital, Tvrtko ; Britvić-Budučin, Smiljana ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Berg, Stefan ; Buchler, Ralph ; Kezić, Nikola | Activity of multixenobiotic resistance mechanism in honeybees // Schedule and Summaries. Molecular Mechanisms of Disease Tolerance in Honeybees.. | Prag, 2000. str. 8-8-x

Izvorni znanstveni rad

Dražić, Maja ; Bubalo, Dragan ; Smital, Tvrtko ; Krča, Sanja, Britvić, Smilja ; Kezić, Nikola | Ekspresija mehanizma multiksenobiotičke otpornosti izlaganjem pčela aktivnim tvarima lijekova // Proceedings, XL Croatian Symposium on Agriculture. | Opatija: Poljoprivredni fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku, 2005. str. 291-293
Sauerborn, Roberta ; Stupin Polancec, Darija ; Zaja, Roko ; Smital, Tvrtko | Identification of the multidrug resistance-associated protein (MRP) related genes in several marine and freshwater fish species // 12th International Symposium on Pollutant Responses in Marine Organisms (PRIMO12) : conference proceedings. | 2003

Publikacije - prilozi sa skupa (u časopisu)

Sažetak izlaganja sa skupa

Karaica, Dean ; Mihaljević, Ivan ; Vujica, Lana ; Dragojević, Jelena ; Bošnjak, Arvena ; Babić, Nency ; Otten Cecile ; Smital, Tvrtko | Improved histological approach for localization and expression analysis of (non)membrane proteins in zebrafish cryosections // FEBS Open Bio, 2022. str. 240-240. doi: 10.1002/2211-5463.13440
doi
Karaica, Dean ; Breljak, Davorka ; Brzica, Hrvoje ; Lončar, Jovica ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković Dupor, Jana ; Mihaljević, Ivan et al. | CFEX (Slc26a6) in rat kidneys, liver, and small intestine in an experimental model of oxalate nephrolitiasis // Arhiv za higijenu rada i toksikologiju, 2015. str. 228-228
hrcak.srce.hrhrcak.srce.hr
Sauerborn Klobučar, Roberta ; Žaja, Roko ; Smital, Tvrtko | ABC transport proteins as mediators of the multixenobiotic resistance (MXR) defence mechanism in aquatic organisms // The FEBS journal, 2005
onlinelibrary.wiley.com
Smital, Tvrtko ; Epel, David ; Britivić, Smiljana ; KrČa, Sanja ; Pivčević, Branka ; Sauerborn Klobučar, Roberta ; Žaja, Roko | Inhibitors of the ABC transport proteins as emerging pollutants— Determination and ecotoxicological relevance // Toxicology letters, 2006. str. S43-S44
www.sciencedirect.com

Publikacije - prilozi sa skupa (neobjavljeni)

Neobjavljeni prilog sa skupa

Vujica, Lana; Mišić, Lana; Horvat, Marina; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish (Danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a3) // 21st International Symposium on Pollutant Responses In Marine Organisms (PRIMO21) | Göteborg, Švedska, 22.05.2022-25.05.2022
Vujica, Lana; Mišić, Lana; Horvat, Marina; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | INTERACTION OF ENVIRONMENTAL CONTAMINANTS WITH ZEBRAFISH (Danio rerio) MULTIDRUG AND TOXIN EXTRUSION PROTEIN 3 (Mate3/Slc47a3) // HDBMB 2022 Congress – From Science to Knowledge | Brela, Hrvatska, 28.09.2022-01.10.2022
Vujica, Lana; Mihaljević, Ivan; Dragojević, Jelena; Lončar, Jovica; Smital, Tvrtko | Phenotype changes in zebrafish Oatp1d1 mutants // Pollutant Responses in Marine Organisms | Nantes, Francuska, 26.05.2024-29.05.2024
primo22.org
Lana Vujica, Jovica Lončar, Lana Mišić, Bono Lučić, Katarina Radman, Ivan Mihaljević, Branimir Bertoša , Josip Mesarić, Marina Horvat, Tvrtko Smital | FIRST IN VITRO AND IN SILICO CHARACTERIZATION OF ZEBRAFISH (DANIO RERIO) MULTIDRUG AND TOXIN EXTRUSION PROTEIN 3 (MATE3/SLC47A2.1) // 12th European Zebrafish Meeting | Krakov, Poljska, 09.07.2023-13.07.2023
Ivanković Koprivić, Klaudija; Dragojević, Jelena; Mihaljević, Ivan; Smital, Tvrtko; Ahel, Marijan; Terzić, Senka | Kinetika akumulacije i eliminacije smjese farmaceutski aktivnih spojeva u modelnom organizmu Danio rerio // 4. Znanstvena škola o okolišu "Nekonvencionalni pristupi konvencionalnim izazovima" | Zagreb, Hrvatska, 27.11.2023-29.11.2023
Žaja, Roko ; Popović, Marta ; Lončar, Jovica ; Fent, Karl, Smital, Tvrtko | Expression and characterization of rainbow trout (Oncorhynchus Mykiss) BCRP (ABCG2) in SF9 insect cells // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Terzić, Senka ; Ahel, Marijan ; Smital, Tvrtko | IDENTIFICATION OF POTENT P-GLYCOPROTEIN (ABCB1) INHIBITORS IN CONTAMINATED SEDIMENT SAMPLES // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Lončar, Jovica ; Žaja, Roko ; Popović, Marta ; Medvedović, Jasna ; Smital, Tvrtko | Tissue distribution and gene expression regulation of MRP9 (abcc12) in rainbow trout and zebrafish // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Smital, Tvrtko ; Žaja, Roko ; Popović, Marta ; Lončar, Jovica | Uptake and efflux transporters versus the adme-tox concept in aquatic toxicology // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Glišic, Branka ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Kovačević, Radmila | Phylogenetic and tissue distribution analysis of glutathione-S-transferase family in zebrafish (Danio rerio) // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | FIRST CHARACTERIZATION OF ZEBRAFISH (Danio rerio) UPTAKE TRANSPORTERS (Solute Carrier families SLC21 and SLC22) // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Della Torre, Camilla ; Lončar, Jovica ; Žaja, Roko ; Focardi Silvano ; Smital, Tvrtko ; Corsi, Ilaria | INVOLVEMENT OF ABC TRANSPORT PROTEINS IN RESPONSE TO TOXIC HEAVY METALS IN THE PLHC-1 FISH CELL LINE // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011
Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Mikac, Iva ; Smital, Tvrtko | Comprehensive Scheme for Non-target Screening of Wastewater and Its Application for the Effect- directed Analysis Municipal Sewage // 13th EuCheMS International Conference on Chemistry and the Environment | Zürich, Švicarska, 11.09.2011-15.09.2011
Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica, Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin V ; Smital, Tvrtko | Relative contribution of polar contaminants to the toxicological profiles of the wastewater effluents of the city of Zagreb (Croatia) // SETAC Europe 20th Annual Meeting | Sevilla, Španjolska, 23.05.2010-27.05.2010

Publikacije - ocjenski radovi

Magistarski rad (znanstveni)

Stepić, Sandra | Utjecaj oksidativnog stresa na izraženost molekularnih biljega kod babuške (Carassius auratus gibelio) i šarana (Cyprinus carpio) / Hackenberger, Dubravka (mentor); Smital, Tvrtko (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2006
Smital, Tvrtko | In vivo određivanje koncentracije inhibitora mehanizma multiksenobiotičke otpornosti (MXR) u riječnim vodama / Kurelec, Branko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1998

Doktorski rad

Dragojević, Jelena | Characterization of organic anion transporters in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, 2018
Marić, Petra | Ecotoxicological characterization of cyanobacteria and invasive algae from the genus Caulerpa using the concept of effects-directed analyses (EDA) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku / Sveučilište u Dubrovniku, 2015
Lončar, Jovica | Function and regulation of ABC transport proteins in rainbow trout (Onchorynchus mykiss) tissues and cell lines / Smital, Tvrtko (mentor). | Zagreb, Sveučilište u Zagrebu, 2015
Mihaljević, Ivan | Characterization of organic cation transporters in zebrafish (Danio rerio Hamilton, 1882) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku / Sveučilište u Dubrovniku, 2015
Popović, Marta | Identification, characterization and ecotoxicological relevance of membrane transport protein families SLC21 and SLC22 in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2014
mobi.unios.hr
Popović, Marta | Identification, characterization and ecotoxicological relevance of membrane transport protein families SLC21 and SLC22 in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2014
mobi.unios.hr
Bošnjak, Ivana | Zaštitna uloga ABC transportnih proteina tijekom ranog embrionalnog razvoja morskih ježinaca / Smital, Tvrtko ; Šver, Lidija (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010
Žaja, Roko | Karakterizacija apikalnih transportera ABC u hepatocitima kalifornijske pastrve (Oncorhynchus mykiss) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010
Traven, Luka | Ekotoksikološka karakterizacija sedimenata Riječkog zaljeva upotrebom in vitro biotestova / Mićović, Vladimir ; Smital, Tvrtko (mentor). | Rijeka, Medicinski fakultet u Rijeci, 2009
Sauerborn Klobučar, Roberta | Karakterizacija mehanizma multiksenobiotičke otpornosti (MXR) vodenih životinja određivanjem MRP-protein kodirajućih gena / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009
Smital, Tvrtko | Aktivnost mehanizma multiksenobiotičke otpornosti u vodenih organizama kao pokazatelj kvalitete okoliša / Kurelec, Branko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1999

Diplomski rad (sveučilišni)

Bule, Kristina | Određivanje toksičnosti mikroplastike / Kučić Grgić, Dajana ; Smital, Tvrtko (mentor); Miloloža, Martina (neposredni voditelj) . | Zagreb, Fakultet kemijskog inženjerstva i tehnologije, 2020
Kerkez, Josip | Toksičnost ekstrakata invazivnih tropskih algi roda Caulerpa / Smital, Tvrtko ; Radić Brkanac, Sandra (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2019
urn.nsk.hr
Šestak, Ivana | Određivanje toksičnosti uzoraka sedimenta potoka Gorjak biotestovima in vitro / Smital, Tvrtko ; Klobučar, Goran (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009
urn.nsk.hr
Krznar, Petra | Genska ekspresija i filogenija MATE (Multidrug and toxin extrusion) proteina u zebrici, Danio rerio (Hamilton, 1822) / Smital, Tvrtko ; Klobučar, Goran (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013
urn.nsk.hr
Krznar, Petra | Expression profiling and phylogeny of MATE (Multidrug and toxin extrusion) proteins in zebrafish, Danio rerio (Hamilton, 1822) / Smital, Tvrtko (mentor); Popović, Marta (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013
Bartolić, Damir | UTVRĐIVANJE ESTROGENOSTI UZORAKA SEDIMENTA I POVRŠINSKE VODE RIJEKE SAVE BIOTESTOM YES / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2011
Crnjak, Martina | Utvrđivanje genotoksičnog potencijala uzoraka sedimenta i površinske vode rijeke Save Ames biotestom / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009
zir.nsk.hr
Marić, Petra | Estrogeni potencijal i koncentracija inhibitora mehanizma multiksenobiotičke otpornosti u sedimentu potoka Gorjak / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009
Šestak, Ivana | Određivanje toksičnosti uzoraka sedimenta potoka Gorjak in vitro biotestovima / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009
zir.nsk.hrurn.nsk.hr
Medvedović, Jasna | Molekularna identifikacija i funkcionalna karakterizacija P-glikoproteina (ABCB1) u slatkovodnog školjkaša vrste Unio pictorum (Linnaeus 1758) / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2007

Publikacije - druge vrste radova

Ostali članci/prilozi

Britvić, Smiljana ; Krča, Sanja ; Kurelec, Branko ; Lucić, Davor ; Pivčević, Branka ; Smital, Tvrtko | Functional and protein expression of multixenobiotic resistance mechanism in a marine mussel as a biomarker of exposure to polluted environments // MAP Technical Report Series No. 103, UNEP, Athens, pp. 29-41, 1998
wedocs.unep.orgagris.fao.org

Izvještaj

Raspor, Biserka ; Smital, Tvrtko ; Klobučar, Goran ; Hackenberger, Branimir | An integrated environmental monitoring system for Croatian freshwater, estuarine and coastal marine areas // Research Council of Norway, Project No. 150463, 2005
Raspor, Biserka ; Teskeredžić, Emin ; Smital, Tvrtko ; Picer, Mladen ; Ahel, Marijan | SARIB project Annual Report of Partner 3 (RBI) // Sixth Framework Programme FP6-2002-INCO-WBC-1, 2005

Članstva u profesionalnim udrugama / društvima

Član Hrvatskog biološkog društva, Hrvatskog toksikološkog društva i Society of Ecotoxicology and Environmental Safety (SECOTOX).

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Pretraži Institut Ruđer Bošković

dr. sc. Tvrtko Smital

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Članstva u profesionalnim udrugama / društvima

Institut Ruđer Bošković

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