Marie Sklodowska-Curie Action - postdoktorska stipendija

Kako se životinjske skupine nose s problemom povećane osjetljivosti na uzročnike bolesti? Život u grupama iznimno je koristan, ali zbog učestalijih kontakata između jedinki, potiče i širenje uzročnika bolesti. Zadružni kukci, kao što su mravi, pčele i termiti, pokazuju izvanrednu bihevioralnu i fiziološku obranu od epidemija u svojim zajednicama, koju pojedinci provode na razini kolonije (tzv. društveni imunitet). Međutim, koji evolucijski procesi upravljaju pojavom takvih i sličnih uzoraka ponašanja protiv uzročnika bolesti na razini skupine? U svojim istraživanjima koristim kukce brašnare koje je moguće eksperimentalno manipulirati u vidu srodsta, veličine skupine i njezine strukture.

Obrazovanje

2014 - Sveučilište u Münsteru, Njemačka, Dr. sc. evolucijske biologije

2009 - Sveučilište u Zagrebu, Hrvatska, Prof. biologije

Publikacije

Stock M*, Milutinović B*, Hoenigsberger M, Grasse AV, Wiesenhofer F, Kampleitner N, Narasimhan M, Schmitt M, Cremer S (2023). Pathogen evasion of social immunity, Nat Ecol Evol 7, 450–460, https://doi.org/10.1038/s41559-023-01981-6

Lo LK, Tewes LJ, Milutinović B, Müller C, Kurtz J (2022). Immune stimulation via wounding alters chemical profiles of adult Tribolium castaneum, J Chem Ecol, doi.org/10.1007/s10886-022-01395-x

Armitage SAO, Milutinović B (2022). Editorial overview: Evolutionary ecology of insect immunity, Curr Opin Insect Sci, doi: 10.1016/j.cois.2022.100948

Milutinović B, Schmitt T (2022). Chemical cues in disease recognition and their immunomodulatory role in insects, Curr Opin Insect Sci, doi: 10.1016/j.cois.2022.100884

Milutinović B, Stock M, Grasse AV, Naderlinger E, Hilbe C, Cremer S (2020). Social immunity modulates competition between coinfecting pathogens, Ecol Lett, doi: 10.1111/ele.13458., research featured as issue cover image.

Greenwood JM*, Milutinović B*, Peuß R, Behrens S, Esser D, Rosenstiel F, Schulenburg H, Kurtz J (2017).  Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae, BMC Genomics; 18:329, doi: 10.1186/s12864-017-3705-7

Milutinović B, Kurtz J (2016). Review article: Immune memory in invertebrates. Semin Immunol. 2016 Aug; 28(4):328-42

Milutinović B*, Peuβ R*, Ferro K, Kurtz J (2016). Review article: Immune priming in arthropods: an update focusing on the red flour beetle. Zoology Mar 24. pii: S0944-2006(16)30018-6

Peuß R, Wensing KU, Woestmann L, Eggert H, Milutinović B, Sroka MGU, Scharsack JP, Kurtz J, Armitage SAO (2016). Down syndrome cell adhesion molecule 1: testing for a role in insect immunity behaviour and reproduction. R Soc Open Sci. 2016 Apr 20;3(4):160138

Milutinović B, Höfling C, Futo M, Scharsack JP, Kurtz J (2015) Infection of Tribolium castaneum with Bacillus thuringiensis: Quantification of bacterial replication within cadavers, transmission via cannibalism, and inhibition of spore germination. Appl Environ Microbiol. 2015 Dec; 81(23):8135-44

Milutinović B, Fritzlar S, Kurtz J (2014) Increased survival in the red flour beetle after oral priming with bacteria-conditioned media. J Innate Immun; 6 (3):306-314

Behrens S, Peuß R, Milutinović B, Eggert H, Esser D, Rosenstiel P, Schulenburg H, Bornberg-Bauer E, Kurtz J (2014): Infection routes matter in population-specific responses of the red flour beetle to the entomopathogen Bacillus thuringiensis, BMC Genomics; 15:445, doi:10.1186/1471-2164-15-445

Milutinović B, Stolpe C, Peuβ R, Armitage SAO, Kurtz J (2013) The red flour beetle as a model for bacterial oral infections. PLoS ONE; 8(5), doi:10.1371/journal.pone.0064638